M.D. Anderson Cancer Center: Carcinoma trials

The registry lists 112 Carcinoma studies with M.D. Anderson Cancer Center as lead sponsor. 3 are open to participants now and 56 have results posted.

Early Phase 1 6Phase 1 31Phase 2 67Phase 3 3Phase 4 1No phase 17(a study in two phases counts in both)

Studies

Page 1 of 2. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial")RecruitingNCT07411599Phase 1/2
• A Phase II Study of Perioperative Paclitaxel in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyRecruitingNCT05977998Phase 2
• Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck CancerRecruitingNCT03010150
• A Phase II Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Mitotane in Patients With Advanced Adrenocortical CarcinomaTerminatedNCT05634577Phase 2Results posted
• Grapiprant and Eribulin for the Treatment of Metastatic Inflammatory Breast CancerTerminatedNCT05041101Phase 1/2Results posted
• A Dual Channel Supraglottic Airway Device (LMA Gastro) for Oxygenation in Patients Undergoing ERCPCompletedNCT04740164Not applicableResults posted
• Alisertib and Pembrolizumab for the Treatment of Patients With Rb-deficient Head and Neck Squamous Cell CancerCompletedNCT04555837Phase 1/2Results posted
• Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial CancerTerminatedNCT04228042Phase 1/2Results posted
• Bintrafusp Alfa and Stereotactic Body Radiation Therapy for the Treatment of Recurrent or Second Primary Head and Neck Squamous Cell CancerTerminatedNCT04220775Phase 1/2Results posted
• An Investigational Scan (18F-Fluciclovine PET-CT) for the Measurement of Therapeutic Response in Patients With Metastatic Prostate CancerTerminatedNCT04134208Phase 4Results posted
• AVB-S6-500 and Durvalumab in Treating Patients With Platinum-Resistant or Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerTerminatedNCT04019288Phase 1/2Results posted
• Axitinib and Avelumab in Treating Patients With Recurrent or Metastatic Adenoid Cystic CarcinomaCompletedNCT03990571Phase 2Results posted
• Atorvastatin in Treating Patients With Stage IIb-III Triple Negative Breast Cancer Who Did Not Achieve a Pathologic Complete Response After Receiving Neoadjuvant ChemotherapyTerminatedNCT03872388Phase 2Results posted
• Bronchoscopic Laser Ablation of Peripheral Lung TumorsTerminatedNCT03707925Not applicableResults posted
• Linear Energy Transfer (LET)-Optimized Intensity Modulated Proton Therapy (IMPT) as a Component of Definitive Chemoradiation for Newly Diagnosed Squamous Cell Carcinoma of the Anal Canal: a Feasibility TrialCompletedNCT03690921Phase 2Results posted
• Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal AdenocarcinomaTerminatedNCT03610490Phase 2Results posted
• DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated CancersTerminatedNCT03439085Phase 2Results posted
• Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical CarcinomaCompletedNCT03370718Phase 2Results posted
• Nivolumab With or Without Ipilimumab in Treating Patients With Resectable Liver CancerCompletedNCT03222076Phase 2Results posted
• Cobimetinib and Atezolizumab in Treating Participants With Advanced or Refractory Rare TumorsCompletedNCT03108131Phase 2Results posted
• Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney CancerCompletedNCT03015740Phase 1/2Results posted
• Paclitaxel and Bevacizumab With or Without Emactuzumab in Treating Patients With Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal CancerTerminatedNCT02923739Phase 2Results posted
• Pemetrexed Disodium in Treating Patients With Previously Treated Metastatic Urothelial CancerTerminatedNCT02693717Phase 2Results posted
• Compassionate Use of Brontictuzumab for Adenoid Cystic Carcinoma (ACC)CompletedNCT02662608Not applicableResults posted
• Talimogene Laherparepvec in Treating Patients With Recurrent Breast Cancer That Cannot Be Removed by SurgeryTerminatedNCT02658812Phase 2Results posted
• Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by SurgeryCompletedNCT02520141Phase 2Results posted
• Liposomal Doxorubicin, Bevacizumab, and Everolimus in Patients With Locally Advanced TNBC With Tumors Predicted Insensitive to Standard Chemotherapy; A Moonshot InitiativeCompletedNCT02456857Phase 2Results posted
• Gemcitabine Hydrochloride, Cisplatin, and Nab-Paclitaxel in Treating Patients With Advanced or Metastatic Biliary CancersCompletedNCT02392637Phase 2Results posted
• Use of High-Resolution Microendoscopy (HRME) in Patients With Adenocarcinoma In-Situ (AIS) of the CervixCompletedNCT02206048Not applicableResults posted
• Sunitinib Scheduling in Metastatic Renal Cell Carcinoma (mRCC)CompletedNCT02060370Phase 2Results posted
• Sorafenib Tosylate and Yttrium Y 90 Glass Microspheres in Treating Patients With Liver Cancer That Cannot Be Removed by SurgeryCompletedNCT01900002Phase 2Results posted
• Telaprevir Plus Standard of Care (SOC) in HCV Associated Hepatocellular Carcinoma (HCC)TerminatedNCT01821963Phase 3Results posted
• Carfilzomib in Refractory Renal Cell Carcinoma (RCC)CompletedNCT01775930Phase 2Results posted
• Cabazitaxel With or Without Carboplatin in Treating Patients With Previously Treated Metastatic Castration-Resistant Prostate CancerCompletedNCT01505868Phase 1/2Results posted
• Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)CompletedNCT01392183Phase 2Results posted
• Cryoablation for Invasive Breast Carcinoma Following Neoadjuvant TherapyTerminatedNCT01388777Phase 2Results posted
• Extraperitoneal Para-aortic Lymph Node Dissection (EPLND) for CervixCompletedNCT01365156Phase 3Results posted
• Neoadjuvant Axitinib in Locally Advanced Renal Cell Carcinoma (RCC)CompletedNCT01263769Phase 2Results posted
• Erlotinib in Treating Patients With Recurrent or Metastatic Skin Squamous Cell CarcinomaCompletedNCT01198028Phase 2Results posted
• Everolimus Versus Sunitinib in Non-Clear Cell Renal Cell CarcinomaTerminatedNCT01185366Phase 2Results posted
• Erlotinib Plus Bevacizumab in Hepatocellular Carcinoma (HCC) as Second-line TherapyCompletedNCT01180959Phase 2Results posted
• First-Line Treatment of Bevacizumab, Carboplatin, and Paclitaxel in Treating Participants With Stage III-IV Ovarian, Primary Peritoneal, and Fallopian Tube CancerCompletedNCT01097746Phase 2Results posted
• Combination Chemotherapy With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and NeckCompletedNCT01064479Phase 2Results posted
• Preoperative Treatment With Cetuximab and/or IMC-A12CompletedNCT00957853Phase 2Results posted
• Trial of Image-Guided Adaptive Conformal Photon vs Proton Therapy, With Concurrent Chemotherapy, for Locally Advanced Non-Small Cell Lung Carcinoma: Treatment Related Pneumonitis and Locoregional RecurrenceCompletedNCT00915005Phase 2Results posted
• Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial CancerCompletedNCT00749892Phase 2Results posted
• Avastin (Bevacizumab) and RAD001 (Everolimus) in Advanced Low or Intermediate Grade Neuroendocrine CarcinomaCompletedNCT00607113Phase 2Results posted
• Low Dose Decitabine + Interferon Alfa-2b in Advanced Renal Cell CarcinomaTerminatedNCT00561912Phase 2Results posted
• Papillary Serous Carcinoma of the EndometriumCompletedNCT00515073Phase 2Results posted
• Neoadjuvant Chemotherapy for Patients With Squamous Cell Carcinoma of the PenisCompletedNCT00512096Phase 2Results posted
• Gleevec/Taxol for Patients With Uterine Papillary Serous CarcinomaTerminatedNCT00506779Phase 1/2Results posted
• Neoadjuvant Herceptin for Ductal Carcinoma In Situ of the BreastCompletedNCT00496808Not applicableResults posted
• Capecitabine, Gemcitabine, and Bevacizumab in Combination for Patients With Sarcomatoid Renal Cell CarcinomaCompletedNCT00496587Phase 2Results posted
• Zoledronate With Atorvastatin in Renal Cell CarcinomaCompletedNCT00490698Phase 2Results posted
• Gemcitabine, Paclitaxel, Doxorubicin in Metastatic or Unresectable Bladder Cancer With Decreased Kidney FunctionCompletedNCT00478361Phase 2Results posted
• Purged Circulating Tumor Cells (CTCs) From Metastatic Breast CancerCompletedNCT00429182Phase 2Results posted
• Efficacy and Safety Study of Bevacizumab and Erlotinib to Treat Primary Liver Cancer That Cannot be Removed By SurgeryCompletedNCT00242502Phase 2Results posted
• Neoadjuvant Clinical Trial to Evaluate the Efficacy of Bevacizumab for Renal Cell CarcinomaCompletedNCT00113217Phase 2Results posted
• ZD1839 (Iressa) for Recurrent or Metastatic Squamous Cell Carcinoma of the SkinCompletedNCT00054691Phase 2Results posted
• Study of VG2025 Delivered Intraperitoneally in Patients With Advanced Solid Tumors With CarcinomatosisWithdrawnNCT06365918Phase 1
• A Study Evaluating Atezolizumab and Bevacizumab Plus ADI-PEG 20 in Patients With Locally Advanced / Metastatic Hepatocellular CarcinomaWithdrawnNCT06006286Phase 1/2
• Phase 2 Study of Neoadjuvant SAR444245 Plus Cemiplimab in HPV Related Oropharynx Squamous Cell CarcinomaWithdrawnNCT05535023Phase 2
• Phase II Trial of Immunotherapy in Patients With Carcinomas Arising From the Renal MedullaActive, not recruitingNCT05347212Phase 2
• A Pilot Study of Glutamine PET Imaging of Head and Neck Squamous Cell CarcinomaTerminatedNCT05322135Early Phase 1
• Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast CancerWithdrawnNCT05177796Phase 2
• Psychological, Psychophysical and Epigenetic Determinants of Chronic Pain After Cytoreductive - Hyperthermic Intraoperative ChemotherapyCompletedNCT05083338
• Treatment Decision Making in African American Women Diagnosed With Triple Negative Breast CancerCompletedNCT05071677
• Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the CervixActive, not recruitingNCT05063916Phase 2
• Gallium-68 PSMA-11 PET in Participants With Prostate CancerWithdrawnNCT05034562Phase 2
• Sapanisertib and Nivolumab for the Treatment of Stage I-IV Non-small Cell Lung Cancer in Patients Who Have Progressed on Prior PD-1/PD-L1 Inhibitor Therapy, I-OVERCOME StudyWithdrawnNCT05022394Phase 1/2
• Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid NoduleTerminatedNCT05003856Not applicable
• An Investigational Scan (rh PSMA 7.3 PET/MRI) for the Detection of Recurrent Disease and Aid in Radiotherapy Planning in Biochemically Recurrent Prostate CancerCompletedNCT04978675Phase 1
• Nivolumab and ADI-PEG 20 Before Surgery for the Treatment of Resectable Liver CancerWithdrawnNCT04965714Phase 2
• Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck CancerCompletedNCT04870840Phase 1
• Re-irradiation With NBTXR3 in Combination With Pembrolizumab for the Treatment of Inoperable Locoregional Recurrent Head and Neck Squamous Cell CancerWithdrawnNCT04834349Phase 2
• Androgen Deprivation Therapy and Apalutamide With or Without Radiation Therapy for the Treatment of Biochemically Recurrent Prostate Cancer, RESTART StudyWithdrawnNCT04585932Phase 2
• Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine CancersWithdrawnNCT04106843Phase 2
• Nutritional Supplementation in Reducing Complications in Patients With Locally Advanced Esophageal Cancer Undergoing Chemotherapy, Radiation Therapy, and/or SurgeryWithdrawnNCT04029857Phase 3
• Effect of PACK Health Support Program on Patient Reported Outcomes in Patients With Breast CancerCompletedNCT04022772Not applicable
• An Investigational Scan (Magnetic Resonance Elastography) in Detecting Treatment Response in Patients With Advanced Liver CancerCompletedNCT04022746Not applicable
• Nurse-Driven Telephone Intervention in Improving Side Effects in Cancer Patients Undergoing ChemotherapyCompletedNCT03964896Not applicable
• Fluciclovine F18 PET/CT in Identifying the Origin of Head and Neck Squamous Cell Carcinoma in Patients With Metastatic Cervical Nodal DiseaseCompletedNCT03868020Early Phase 1
• A Phase I Study of SOR-C13 in Patients With Advanced Solid TumorsCompletedNCT03784677Phase 1
• TAK-659 and Paclitaxel in Treating Patients With Advanced Solid TumorsCompletedNCT03756818Phase 1
• Nivolumab With or Without Ipilimumab in Treating Patients With Recurrent or High Grade Gynecologic Cancer With Metastatic Peritoneal CarcinomatosisCompletedNCT03508570Phase 1
• Daratumumab in Treating Patients with Muscle Invasive Bladder Cancer or Metastatic Kidney CancerCompletedNCT03473730Early Phase 1
• Stereotactic Body Radiation Therapy, Tremelimumab and Durvalumab in Treating Participants With Recurrent or Metastatic Cervical, Vaginal, or Vulvar CancersCompletedNCT03452332Phase 1
• Study of Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Patients With Gastric Adenocarcinoma and Carcinomatosis or Positive CytologyCompletedNCT03330028Phase 1
• Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast CancerCompletedNCT03207529Phase 1
• Durvalumab With or Without Tremelimumab in Treating Participants With Stage II-IVA Oropharyngeal Squamous Cell CancerCompletedNCT03144778Phase 1
• Danvatirsen and Durvalumab in Treating Patients With Advanced and Refractory Pancreatic, Non-Small Cell Lung Cancer, and Mismatch Repair Deficient Colorectal CancerActive, not recruitingNCT02983578Phase 2
• PD 0360324 and Cyclophosphamide in Treating Patients With Recurrent High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube CancerWithdrawnNCT02948101Phase 2
• CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal TumorsTerminatedNCT02757391Phase 1
• Intensity-Modulated Proton Therapy (IMPT) or TransOral Robotic Surgery (TORS) for the Treatment of Low-Risk Oropharynx Squamous CellStatus unknownNCT02663583
• Adavosertib Before Surgery in Treating Patients With Advanced High Grade Ovarian, Fallopian Tube, or Primary Peritoneal CancerActive, not recruitingNCT02659241Early Phase 1
• Tremelimumab With or Without Cryoablation in Treating Patients With Metastatic Kidney CancerCompletedNCT02626130Early Phase 1
• Effect of Cabozantinib S-Malate or Lenvatinib Mesylate on Weight and Body Composition in Patients With Metastatic Endocrine CancerCompletedNCT02592356Not applicable
• Phase IB Study to Evaluate the Safety of Selinexor (KPT-330) in Combination With Multiple Standard Chemotherapy or Immunotherapy Agents in Patients With Advanced MalignanciesTerminatedNCT02419495Phase 1
• Cisplatin, Docetaxel, and Nintedanib Before Surgery in Treating Patients With Previously Untreated Stage IB-IIIA Non-small Cell Lung CancerCompletedNCT02225405Phase 1
• Everolimus, Letrozole and Trastuzumab in HR- and HER2/Neu-positive PatientsCompletedNCT02152943Phase 1