Imperial College London: Asthma trials

The registry lists 38 Asthma studies with Imperial College London as lead sponsor. 5 are open to participants now and 19 have results posted.

Early Phase 1 1Phase 2 2Phase 4 7No phase 28(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• London Asthma Diagnostics StudyNot yet recruitingNCT06383130
• Non-Eosinophilic Biological Effects of IL-5RecruitingNCT06026202
• Early Antiviral Responses to Rhinovirus Infection in AsthmaRecruitingNCT05050903
• Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic SettingRecruitingNCT05012033
• Pulmonary Epithelium, Immunology and Development of Asthma: Breathing TogetherRecruitingNCT04063631
• Financial Incentives to Improve AsthmaCompletedNCT05322044Not applicableResults posted
• Novel Electronic Monitoring Devices (NEMD) to Monitor Adherence in Children With AsthmaCompletedNCT04289714Not applicableResults posted
• Safety of Nasal Influenza Immunisation in Children With AsthmaCompletedNCT02866942Phase 4Results posted
• In Vitro Evaluation of a Novel Drug on Airway Epithelial Cells Obtained From Participants With Severe AsthmaCompletedNCT02740049Early Phase 1Results posted
• Exhaled Hydrogen Sulphide as a Biomarker of Airways Disease in AsthmaCompletedNCT02703467Results posted
• Exacerbations in Severe Asthma Patients: Mechanisms and BiomarkersCompletedNCT02660853Not applicableResults posted
• Effect of OC459 on the Response to Rhinovirus Challenge in AsthmaCompletedNCT02660489Phase 2Results posted
• Conducting Annual Asthma Reviews Using Telehealthcare: Comparison With Standard Care (Face-to-face Consultations)CompletedNCT02545998Not applicableResults posted
• Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT01721291Phase 4Results posted
• The Clinical Effect of Monodisperse Fluticasone Propionate in AsthmaCompletedNCT01662778Phase 4Results posted
• Airway Smooth Muscle and Asthma SeverityCompletedNCT00779870Results posted
• The Natural History of Small Airways Physiology in Diseased and Healthy StatesCompletedNCT00677560Results posted
• p38 Mitogen-Activated Protein Kinase (MAPK) and Steroid Insensitivity in AsthmaCompletedNCT00676572Results posted
• Prednisolone Pharmacokinetics in Severe AsthmaCompletedNCT00662298Phase 4Results posted
• Inflammation and Corticosteroid Responsiveness in Severe AsthmaCompletedNCT00180661Results posted
• Effect of Symbicort on GR Localisation in AsthmaCompletedNCT00159263Not applicableResults posted
• Leukocyte Function in Asthma and COPDCompletedNCT00147069Results posted
• Trial of Lay-led Individualised Self-management Education for Adults With AsthmaCompletedNCT00129987Not applicableResults posted
• Health Effects of Diesel Exhaust in Asthmatic Patients: A Real-world Study in a London StreetCompletedNCT00127062Not applicableResults posted
• Mechanisms of Adverse Effects of Long-Acting Beta-Agonists in AsthmaStatus unknownNCT04503460Phase 4
• Phenotyping Circulating and Lung Resident Eosinophils in Severe Asthma (P-CLESA)Status unknownNCT04463836
• Disclosure of Smoking in Adolescents With AsthmaStatus unknownNCT03047902Not applicable
• Fluctuation of Airway Function in Children With AsthmaCompletedNCT02252289
• Mechanisms of Interplay Between Allergy and Viruses in AsthmaCompletedNCT01773590Not applicable
• AZithromycin Against pLacebo in Exacerbations of AsthmaCompletedNCT01444469Phase 4
• Mechanisms of Rhinovirus Induced Asthma ExacerbationsCompletedNCT01159782Not applicable
• Inhaled Corticosteroids on Airway Smooth Muscle in AsthmaWithdrawnNCT00661973Phase 4
• TNF-alpha Directed Therapy in AsthmaCompletedNCT00278083Phase 2
• Molecular Mechanism of AsthmaWithdrawnNCT00180726Not applicable
• Nitric Oxide (NO) Donors and Inhibitors Study: Study to Evaluate L-Arginine and Aminoguanidine in Asthmatic SubjectsCompletedNCT00159380Not applicable
• ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)CompletedNCT00159315Not applicable
• Biomarkers of iNOS Activity in COPD, Asthma, Healthy ControlWithdrawnNCT00159302
• Comprehension and Evaluation of a Pictorial Action Plan for Those With Asthma or COPDCompletedNCT00129662Not applicable