Idorsia Pharmaceuticals Ltd.: all 103 studies

Page 1 of 2. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• A Trial to See if Daridorexant Can Help Adults and Elderly People With Insomnia Sleep Better During the Night and Function Better During the DayNot yet recruitingNCT07843329Phase 3
• A Study to Learn How Well Lucerastat Works and How Safe it is in Untreated Adult Male Participants With Fabry DiseaseNot yet recruitingNCT07778667Phase 3
• Post Trial Access to Lucerastat for Patients With Fabry Disease Who Participated in Study ID-069A302AvailableNCT07762638
• A Study to Learn How Safe ACT-777991 is and How Well it Works in Adults With Non-segmental VitiligoNot yet recruitingNCT07667569Phase 2
• Registry to Collect Information on Pregnancy, Neonatal, and Infant Outcomes in Pregnant Women Exposed to QUVIVIQ®RecruitingNCT06498128
• A Study to Find Out if Daridorexant is Safe and Efficacious in Patients With Insomnia and Comorbid NocturiaCompletedNCT05597020Phase 4Results posted
• Multicenter Study to Evaluate the Efficacy and Safety of Oral ACT-539313 in the Treatment of Adults With Moderate to Severe Binge Eating DisorderCompletedNCT04753164Phase 2Results posted
• A Study to Evaluate the Effect of ACT-774312 in Subjects With Bilateral Nasal PolyposisCompletedNCT03688555Phase 2Results posted
• Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to SleepCompletedNCT03679884Phase 3Results posted
• Clinical Research Study With Clazosentan to Evaluate Its Effects on Preventing Complications Due to the Narrowing of the Blood Vessels (Vasospasm) in the Brain, Caused by Bleeding Onto the Surface of the BrainCompletedNCT03585270Phase 3Results posted
• Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to SleepCompletedNCT03575104Phase 3Results posted
• Study to Assess the Efficacy and Safety of ACT-541468 (Daridorexant) in Adult and Elderly Subjects With Insomnia DisorderCompletedNCT03545191Phase 3Results posted
• A Research Study to Show the Effect of Aprocitentan in the Treatment of Difficult to Control (Resistant) High Blood Pressure (Hypertension) and Find Out More About Its SafetyCompletedNCT03541174Phase 3Results posted
• Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry DiseaseCompletedNCT03425539Phase 3Results posted
• Efficacy and Safety of ACT-541468 in Elderly Subjects With Insomnia DisorderCompletedNCT02841709Phase 2Results posted
• Efficacy and Safety of ACT-541468 in Adult Subjects With Insomnia DisorderCompletedNCT02839200Phase 2Results posted
• Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential HypertensionCompletedNCT02603809Phase 2Results posted
• Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy SubjectsCompletedNCT02223871Phase 1Results posted
• A Drug-drug Interaction Trial in Healthy Female Participants to Investigate the Effect of Aprocitentan on Combined Hormonal ContraceptivesCompletedNCT06799884Phase 1
• Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)Active, not recruitingNCT06393504
• A Phase 1 Trial to Investigate the Biological Equivalence of 5 × 10 mg Tablets and 2 × 25 mg Tablets of Daridorexant in Healthy Male and Female Japanese ParticipantsCompletedNCT05877222Phase 1
• A Study of the Effect of Daridorexant on Nighttime Body Posture, the Noise Level Required to Wake up, and the Ability to Remember Words Previously PresentedCompletedNCT05702177Phase 1
• A Study to Measure Daridorexant in Breast Milk of Healthy Lactating WomenCompletedNCT05632393Phase 1
• A Study to Investigate the Effect of Itraconazole on the Way the Body Absorbs, Distributes, and Gets Rid of ACT-1004-1239 Given as a Single Dose of 10 mg to Healthy Male SubjectsCompletedNCT05549531Phase 1
• A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Midazolam and Warfarin in Healthy Male SubjectsCompletedNCT05480488Phase 1
• A Study to Examine the Effect of Daridorexant on the Way the Body Absorbs, Distributes, and Gets Rid of Dabigatran and Rosuvastatin in Healthy Male SubjectsCompletedNCT05480475Phase 1
• A Study to Investigate the Effects of Daridorexant on Nighttime Breathing in Patients With Shallow or Paused Breath During SleepCompletedNCT05458193Phase 1
• Dose-finding Study Assessing the Efficacy, Safety, and Pharmacokinetics of Daridorexant in Subjects Aged 10 to < 18 Years With Insomnia DisorderCompletedNCT05423717Phase 2
• A Study to Investigate the Effect of Single and Repeated Oral Doses of ACT-539313 on What the Body Does to Flurbiprofen, Omeprazole, Midazolam in Healthy SubjectsCompletedNCT05254548Phase 1
• Bioequivalence Study of Different Aprocitentan Tablet FormulationsCompletedNCT05196399Phase 1
• Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470CompletedNCT05123820Phase 1
• A Study to Investigate the Pharmacokinetics of ACT-1014-6470 in Subjects With Severe Renal Impairment Compared to Control SubjectsCompletedNCT04899219Phase 1
• A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-777991 in Healthy SubjectsCompletedNCT04798209Phase 1
• A Placebo-controlled Phase 1 Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy SubjectsCompletedNCT04608513Phase 1
• Natural History Study for Pediatric Patients With Early Onset of Either GM1 Gangliosidosis, GM2 Gangliosidoses, or Gaucher Disease Type 2CompletedNCT04470713
• A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478TerminatedNCT04452006Phase 1
• A Study in Healthy Male Subjects to Investigate the Effect of Famotidine and Efavirenz on the Way the Body Takes up, Distributes, and Gets Rid of Daridorexant.CompletedNCT04390334Phase 1
• Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239CompletedNCT04286750Phase 1
• To Study the Effect of Aprocitentan on the Electrical Activity of the Heart in Healthy Men and WomenCompletedNCT04281342Phase 1
• The Effect of Hepatic Impairment on Aprocitentan PharmacokineticsCompletedNCT04252495Phase 1
• A Study to Assess the Effect of Single Doses of Daridorexant on Electrocardiogram Parameters in Healthy SubjectsCompletedNCT04250506Phase 1
• A Study to Examine the Safety, Tolerability, and Pharmacokinetics of Single- and Multiple-ascending Doses of ACT-1014-6470 in Healthy SubjectsCompletedNCT04183686Phase 1
• A Research Study to Show Aprocitentan is Efficacious and Safe to Treat Patients With Uncontrolled Blood Pressure and Chronic Kidney Disease.WithdrawnNCT04162366Phase 3
• A Study to Compare a Single-dose of Two Different Formulations of ACT-709478 in Healthy MenCompletedNCT04123288Phase 1
• Study of the Way the Body Takes up, Distributes, and Gets Rid of ACT-541468 in Subjects With Abnormal Kidney Function Compared to Healthy SubjectsCompletedNCT04024332Phase 1
• A Study to Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney DiseaseCompletedNCT03913000Phase 1
• A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female SubjectsCompletedNCT03907215Phase 1
• A Clinical Study to Assess Next-day Driving Performance Following Administration of ACT-541468 in Middle-aged and Elderly SubjectsCompletedNCT03892902Phase 1
• A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of ACT-1004-1239 in Healthy Male SubjectsCompletedNCT03869320Phase 1
• A Study in Healthy Subjects to Investigate Whether Administration of Lucerastat Can Affect Normal Heart FunctionCompletedNCT03832452Phase 1
• A Clinical Study to Investigate the Food Effect on the Pharmacokinetics of ACT-541468 in Healthy Male SubjectsCompletedNCT03799978Phase 1
• A Study to Investigate the Effects of ACT-541468 on Nighttime Respiratory Function in Patients With Mild to Moderate Obstructive Sleep ApneaCompletedNCT03765294Phase 1
• A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry DiseaseActive, not recruitingNCT03737214Phase 3
• A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic ImpairmentCompletedNCT03713242Phase 1
• A Study in Healthy Subjects to Investigate Whether Administration of Clazosentan Can Affect Normal Heart FunctionCompletedNCT03657446Phase 1
• Study to Evaluate the Abuse Potential of ACT-541468 in Healthy Recreational Drug UsersCompletedNCT03657355Phase 1
• A Study to Evaluate the Effects of ACT-541468 on Respiration in Patients With Moderate Chronic Obstructive Pulmonary DiseaseCompletedNCT03646864Phase 1
• A Study to Investigate the Drug-drug Interactions Between ACT-541468 and Ethanol in Healthy SubjectsCompletedNCT03609775Phase 1
• A Study in Healthy Male Subjects to Investigate Whether Administration of Rifampicin Can Affect the Fate of Clazosentan in the Body of ClazosentanCompletedNCT03596294Phase 1
• A Study to Evaluate How Aprocitentan is Safe and How it is Absorbed and Broken Down in the Body of Japanese and Caucasian SubjectsCompletedNCT03586570Phase 1
• Effect of Cimetidine on the Pharmacokinetics of Lucerastat in Healthy SubjectsCompletedNCT03380455Phase 1
• A Study to Evaluate if ID-085 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy SubjectsCompletedNCT03372629Phase 1
• Pharmacokinetic Interaction Between Midazolam and ID-082 in Healthy SubjectsCompletedNCT03363984Phase 1
• A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of RosuvastatinCompletedNCT03339752Phase 1
• A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-132577 Can Affect Rosuvastatin's Fate in the Body (Amount and Time of Presence in the Blood)CompletedNCT03245229Phase 1
• A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy PatientsCompletedNCT03239691Phase 2
• Study to Evaluate Safety and Tolerability of ACT-709478 in Healthy SubjectsCompletedNCT03165097Phase 1
• A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney DiseaseCompletedNCT03165071Phase 1
• A Study of ACT-541468 in Healthy Japanese and Caucasian SubjectsCompletedNCT03101189Phase 1
• A Study to Evaluate ACT-132577 in Healthy Male SubjectsCompletedNCT03100591Phase 1
• Study to Validate the Questionnaire Called IDSIQ™ in Patients With Insomnia DisorderCompletedNCT03056053Phase 2
• A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and MidazolamCompletedNCT03017495Phase 1
• A Study to Assess the Safety and Pharmacokinetics of Lucerastat (OGT 923) in Healthy SubjectsCompletedNCT02944487Phase 1
• A Study to Assess the Safety, Tolerability and Pharmacokinetics of Lucerastat (CDP923) After Multiple Dosing in Healthy SubjectsCompletedNCT02944474Phase 1
• A Study to Assess the Safety and Tolerability of Lucerastat in Subjects With Fabry DiseaseCompletedNCT02930655Phase 1
• A Single Ascending Dose Study of ACT-541468 in Healthy Male SubjectsCompletedNCT02919319Phase 1
• A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy SubjectsTerminatedNCT02905253Phase 1
• A Study to Investigate the Effect of ACT-132577 on the Pharmacokinetics of Midazolam and 1-hydroxy Midazolam in Healthy Male SubjectsCompletedNCT02841761Phase 1
• First-in-man Study of Single Ascending Dose of a New Drug for Neurological DisordersCompletedNCT02719197Phase 1
• Clinical Study to Assess Body Fluid Homeostasis After Administration of ACT-132577 in Healthy SubjectsCompletedNCT02708004Phase 1
• First-in-man Study of Single and Multiple Ascending Doses of a New Drug for Neurological DisordersCompletedNCT02702648Phase 1
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly SubjectsCompletedNCT02571855Phase 1
• Evaluation of the Efficacy and Safety of Clazosentan in Reversing Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid HemorrhageCompletedNCT02560532Phase 2
• Pharmacokinetic Interaction Between Diltiazem and ACT-541468 in Healthy SubjectsCompletedNCT02526888Phase 1
• A Study to Assess the Tolerability, Safety, Pharmacodynamics, and Pharmacokinetics of Ascending Single Doses (Including Food Interaction) and Ascending Multiple Doses of ACT-453859, and Multiple Doses of Setipiprant (ACT-129968)CompletedNCT02381496Phase 1
• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-451840 in Healthy Subjects (Part A)CompletedNCT02186002Phase 1
• Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-389949 in Healthy SubjectsCompletedNCT02099201Phase 1
• Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-389949CompletedNCT02099071Phase 1
• Single-ascending Oral Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT-281959 / ACT-246475 in Healthy Male SubjectsCompletedNCT01954615Phase 1
• Single-ascending Dose Study to Investigate the Tolerability, Safety, Pharmacokinetics, and Pharmacodynamics of ACT-462206CompletedNCT01954589Phase 1
• Clinical Study to Assess the Pharmacokinetics, Safety, and Tolerability of ACT-129968 in Healthy SubjectsCompletedNCT01877629Phase 1
• Efficacy, Safety, and Tolerability Study of ACT-129968 in Patients With Seasonal Allergic RhinitisCompletedNCT01484119Phase 3
• Essential HypertensionCompletedNCT01264692Phase 2
• Study of ACT-129968 in Adult Patients With Seasonal Allergic RhinitisCompletedNCT01241214Phase 2
• Clinical Study to Explore the Efficacy of ACT-129968 in Patients With Partly Controlled AsthmaCompletedNCT01225315Phase 2
• Tezosentan in Patients With Pulmonary Arterial HypertensionTerminatedNCT01094067Phase 2
• Tezosentan in Pulmonary Arterial HypertensionTerminatedNCT01077297Phase 2
• Clazosentan in Aneurysmal Subarachnoid HemorrhageTerminatedNCT00940095Phase 3
• Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical ClippingCompletedNCT00558311Phase 3
• Tezosentan in Acute Heart FailureCompletedNCT00525707Phase 3

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