H. Lee Moffitt Cancer Center and Research Institute: Breast Neoplasms trials

The registry lists 49 Breast Neoplasms studies with H. Lee Moffitt Cancer Center and Research Institute as lead sponsor. 13 are open to participants now and 12 have results posted.

Early Phase 1 4Phase 1 14Phase 2 22Phase 3 1Phase 4 1No phase 12(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Trial of Therapies With IT cDC1s Combined w/ IT Trastuzamab for Her+ or IT Nivolumab for Her- BC LMDRecruitingNCT07694986Phase 2
• Evaluation and Outcomes of SAVI Scout MD for Localized Breast SurgeryRecruitingNCT07686250Phase 2
• PRehabilitation Intervention to Modify Eating for Breast Cancer Patients (PRIME)Not yet recruitingNCT07638150Not applicable
• Phase III Trial of Brain MRI Surveillance in Stage IV Breast CancerRecruitingNCT07357298Phase 3
• The MIND-BC Study: MIND Diet for Breast Cancer CognitionRecruitingNCT07018986Not applicable
• Phase II Study of Systemic Screening in Pathologic Node Positive Breast CancerRecruitingNCT06833502Phase 2
• Personalized Dendritic Cell Vaccine Pilot for High Risk TNBC After Neoadjuvant TherapyRecruitingNCT06435351Early Phase 1
• Sequential Therapies Modeled on Evolutionary Dynamics for Breast CancerRecruitingNCT06409390Phase 2
• Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain MetastasesRecruitingNCT06238921Phase 1/2
• Genomically Guided Radiation Therapy in the Management of Triple Negative Breast CancerRecruitingNCT05528133Phase 2
• DecipHER Trial - DC1 Tx for Early-Stage TNBC and ER Low Positive Breast CancerRecruitingNCT05504707Phase 1
• Study of HER2 Directed Dendritic Cell (DC1) Vaccine + Weekly Paclitaxel, Trastuzumab & PertuzumabRecruitingNCT05325632Phase 2
• Study of Screening Brain MRIs in Stage IV Breast CancerRecruitingNCT05115474Phase 2
• Aromatase Inhibitor and Durvalumab in Postmenopausal Breast CancerTerminatedNCT03874325Phase 2Results posted
• Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast CancerTerminatedNCT03137693Not applicableResults posted
• Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast CancerCompletedNCT03112590Phase 1/2Results posted
• Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast CancerCompletedNCT02779855Phase 1/2Results posted
• TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast CancerCompletedNCT02586675Phase 1Results posted
• Multicenter Study of Pharmacokinetic-Guided Docetaxel in Breast Cancer Patients Receiving Docetaxel and CyclophosphamideCompletedNCT02502864Phase 4Results posted
• Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC)CompletedNCT02402764Phase 2Results posted
• Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast CancerCompletedNCT02139358Phase 1/2Results posted
• HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast CancerCompletedNCT02063724Phase 1Results posted
• COGNUTRIN in Breast Cancer SurvivorsCompletedNCT01823991Early Phase 1Results posted
• Vaccine Therapy and 1-MT in Treating Patients With Metastatic Breast CancerCompletedNCT01042535Phase 1/2Results posted
• Phase II Trial of SAHA & Tamoxifen for Patients With Breast CancerCompletedNCT00365599Phase 2Results posted
• Breast Cancer Survivors RESET (Reducing Weight and Elevated Stress Levels Using Educational and Behavioral Tools): A Pilot, Feasibility StudyCompletedNCT07101861Not applicable
• Immunologic Targeting of ESR1 Receptor for Hormone Receptor Expressing Metastatic Breast CancerActive, not recruitingNCT06691035Phase 1
• Adoptive T Cell Therapy Following HER2-Pulsed Dendritic Cell Vaccine & Pepinemab /Trastuzumab in Patients w/ Metastatic HER2+ Breast CancerSuspendedNCT05378464Phase 1
• Capecitabine In Combination With Cemiplimab In Patient With Metastatic Breast CancerCompletedNCT05064085Phase 1
• Evaluation of EnVisio SmartClip for Intraoperative Localization of Breast MassesCompletedNCT04604561
• Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain MetastasesCompletedNCT03807765Phase 1
• Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1TerminatedNCT03630809Phase 2
• HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast CancerCompletedNCT03387553Early Phase 1
• Vaccine to Prevent Recurrence in Patients With HER-2 Positive Breast CancerActive, not recruitingNCT03384914Phase 2
• PET-CT Imaging Using FDG-labeled Human Erythrocytes in Breast Cancer PatientWithdrawnNCT03295695Early Phase 1
• Genetic Counseling for Breast Cancer Survivors (GC for BC)CompletedNCT02451735Not applicable
• HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer Post Neoadjuvant ChemotherapyCompletedNCT02061423Phase 1
• Yoga for Aromatase Inhibitor-associated Joint PainCompletedNCT01951976Not applicable
• A Phase I Dose Escalation Study of Eribulin Plus Weekly Carboplatin for Metastatic Breast PatientsCompletedNCT01795586Phase 1
• Promoting a Healthier Lifestyle Among Breast Cancer SurvivorsCompletedNCT01419613Not applicable
• C11 AMT Positron Emission Tomography (PET) Imaging in Patients With Metastatic Invasive Breast CancerWithdrawnNCT01302821Not applicable
• Liposuction for Arm Lymphedema Following Breast Cancer SurgeryCompletedNCT00816985Not applicable
• Pilot Study to Validate Metallic Markers for Image Guided Radiation Therapy for Breast Cancer TxCompletedNCT00802932
• Isoflavones in Treating Women Who Have Breast Cancer and Are Planning to Undergo Mastectomy or LumpectomyTerminatedNCT00036686Not applicable
• ERA-923 in Treating Postmenopausal Women With Metastatic Breast CancerStatus unknownNCT00006369Phase 2
• Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast CancerTerminatedNCT00006032Phase 2
• Doxorubicin and Docetaxel in Treating Women With Stage III Breast CancerCompletedNCT00005800Phase 2
• Combination Chemotherapy Followed By Peripheral Stem Cell Transplantation in Treating Women With Breast CancerCompletedNCT00005798Phase 2
• Management of Metastatic Breast Cancer in Frail PatientsWithdrawnNCT00005614Phase 2