Fudan University: Rectal Neoplasms trials

The registry lists 38 Rectal Neoplasms studies with Fudan University as lead sponsor. 18 are open to participants now and 0 have results posted.

Phase 1 2Phase 2 20Phase 3 4No phase 15(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Total Neoadjuvant mFOLFOX6 Plus Suvemcitug and Enlonstobart With Selective Omission of Pelvic Radiotherapy for High-Risk Mid-Rectal Locally Advanced Rectal CancerNot yet recruitingNCT07810114Phase 2
• Low Rectal Cancer Treated With Total Neoadjuvant Therapy Plus Concurrent Tislelizumab ImmunotherapyRecruitingNCT07561060Phase 1/2
• Neoadjuvant Moderately Hypofractionated Radiotherapy Combined With Chemotherapy and Immunotherapy for High-risk pMMR/MSS Locally Advanced Rectal Cancer: A Prospective, Multi-center Randomized Control Phase II TrialNot yet recruitingNCT07527520Phase 2
• Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 StudyRecruitingNCT07132463Phase 3
• Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal CancerNot yet recruitingNCT06956976Not applicable
• Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal CancerRecruitingNCT06928584Phase 2
• MRD-Guided Surveillance in Locally Advanced Mid-Low Rectal Cancer (SURVEILLANCE-III)Not yet recruitingNCT06879899
• MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal CancerRecruitingNCT06840665Phase 2
• CGA Guided Ultrafractionated RT and First-line Systemic Treatment in Elderly or Frail Patients with MCRCNot yet recruitingNCT06665087Phase 2
• CGA Guided Ultrafractionated RT and Systemic Treatment in Elderly or Frail Patients with Inoperable Localized CRCNot yet recruitingNCT06652412Phase 2
• Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)RecruitingNCT06455124Phase 2
• Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 StudyNot yet recruitingNCT06390982Phase 2
• Neoadjuvant Envafolimab in Resectable and Locally Advanced MSI-H/dMMR Rectal CancerNot yet recruitingNCT05645094
• The Combination of Hypofractionated Radiotherapy and Immunotherapy in Locally Recurrent Rectal CancerRecruitingNCT05628038Phase 2
• The Combination of Immunotherapy and Neoadjuvant Short-course Radiotherapy in Early Rectal CancerRecruitingNCT05555888Phase 2
• A Combination Therapy Including Anti-PD-1 Immunotherapy in MSS Rectal Cancer With Resectable Distal MetastasisNot yet recruitingNCT05359393Phase 2
• Neoadjuvant FOLFOXIRI Versus CapeOX Chemotherapy for Local Advanced Rectal CancerRecruitingNCT05201430Phase 3
• An Adaptive-design Prospective Cohort Study of Watch and Wait Strategy in Patients With Locally Advanced Rectal CancerNot yet recruitingNCT04443543Phase 2
• Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal CancerCompletedNCT06542354Not applicable
• Dosimetric Limitation of Pelvic Bone and Peritoneal Space in Rectal Cancer Patients During ChemoradiotherapyStatus unknownNCT05688033Not applicable
• Short-course Radiotherapy Based TNT Combined With PD-1 Inhibitor for Locally Advanced Rectal CancerCompletedNCT04518280Phase 2
• The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSS Locally Advanced Rectal CancerStatus unknownNCT04411537Phase 2
• The Combination of Immunotherapy and Neoadjuvant Chemoradiotherapy in MSI-H Locally Advanced Rectal CancerStatus unknownNCT04411524Phase 2
• A Study of Chinese Herbal Compound Dendrobium Huoshanense Granules in NCRT for Patients With Locally Advanced Rectal CancerStatus unknownNCT04394598Phase 2
• Study on Predictive Biomarkers of Neoadjuvant Chemoradiotherapy for Rectal CancerStatus unknownNCT04227886
• Fluorescent Lymphography-Guided Lymphadenectomy In Laparoscopic ProctectomyStatus unknownNCT03854890Not applicable
• UGT1A1 Combined With Pharmacokinetics of SN-38 in CPT-11-based CRT in Patients With Advanced Rectal CancerStatus unknownNCT03824899Not applicable
• Radiation-protection Effect of Amifostine in Locally Advanced Rectal CancerStatus unknownNCT03702985Phase 2
• Application of Left Colic Artery Preservation, Anastomotic Reinforcing Sutures and Transanal Tube in Robotic Low Anterior ResectionStatus unknownNCT03609710Not applicable
• Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal CancerStatus unknownNCT02905968Phase 2/3
• Robot-assisted Versus Laparoscopic Surgery for Mid/Low Rectal CancerStatus unknownNCT02817126Not applicable
• A Prospective Clinical Study for Laparoscopic D3 Dissection With Preservation of Left Colic Artery in Rectal CancerStatus unknownNCT02753465Not applicable
• A Prospective Clinical Study for Transanal Double Purse-string Rectal Anastomosis Preformed With KOL StaplerStatus unknownNCT02565667Not applicable
• A Trial of Robotic-assisted Versus Laparoscopic Abdominoperineal Resection for Treating Low Rectal CancerCompletedNCT01985698Not applicable
• Detection and Enumeration of Circulating Tumor Cells in Rectal CancerStatus unknownNCT01671891
• Genotype-driven Phase I Study of Irinotecan Administered in Neoadjuvant Chemoradiotherapy in Patients With Stage II/III Rectal CancerStatus unknownNCT01474187Phase 1
• A Trial of High Intensity Versus Low Intensity Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal CancerStatus unknownNCT01064999Phase 2/3
• Simultaneous Versus Staged Resection for Initially Resectable Synchronous Rectal Cancer Liver-limited MetastasisCompletedNCT00677586Not applicable