Dompé Farmaceutici S.p.A: all 52 studies

Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.

• An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCEDRecruitingNCT07519902Phase 3
• An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye DiseaseRecruitingNCT07503886Phase 2
• Efficacy and Safety of Intranasal Cenegermin in Adult Participants With Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)RecruitingNCT07453888Phase 3
• An Efficacy and Safety Study of DFL24498 in the Treatment of AKCRecruitingNCT07395232Phase 3
• A Safety and Efficacy Study of 2 Dosing Regimens of Recombinant Human Nerve Growth Factor (rhNGF) Eye Drop Solution Compared With Vehicle in Patients With Dry Eye Disease.CompletedNCT06244316Phase 2Results posted
• DEFENDO Long Term Follow-up Study in Stage 1 NK PatientsCompletedNCT05552261Results posted
• Add-on Reparixin in Adult Patients With ARDSCompletedNCT05496868Phase 2Results posted
• Clinical Trial on Ladarixin Adjunctive Therapy to Improve Glycemic Control in Type 1 Diabetes.TerminatedNCT05368402Phase 2Results posted
• Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired PneumoniaTerminatedNCT05254990Phase 3Results posted
• Multicenter Double Blind, Parallel-group Phase 2/3 Trial, to Study Raloxifene in Adult COVID-19 Patients.CompletedNCT05172050Phase 2/3Results posted
• Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye DiseaseCompletedNCT05136170Phase 3Results posted
• Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)CompletedNCT05133180Phase 3Results posted
• A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.TerminatedNCT04899271Phase 2Results posted
• Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneumonia.CompletedNCT04878055Phase 3Results posted
• A Single Dose Study About the Influence of Food on the Oral Bioavailability of Ladarixin Capsule in Healthy VolunteersCompletedNCT04854642Phase 1Results posted
• Ascending Dose Tolerability Trial and PK Assessment in Healthy Volunteers After Single & Multiple Oral Intake of DF2755ATerminatedNCT04803396Phase 1Results posted
• A Study on Ketoprofen Lysine Salt (KLS) + Gabapentin (GABA) vs KLS to Investigate Their Pharmacodynamic in Healthy MalesCompletedNCT04802967Phase 1Results posted
• Reparixin in COVID-19 Pneumonia - Efficacy and SafetyTerminatedNCT04794803Phase 2/3Results posted
• A Study of Oral Ladarixin in Recent Onset Type 1 Diabetes and a Low Residual β-cell FunctionTerminatedNCT04628481Phase 2Results posted
• Study to Evaluate OXERVATE® in Patients With Stage 1 Neurotrophic KeratitisCompletedNCT04485546Phase 4Results posted
• A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry EyeCompletedNCT03982368Phase 2Results posted
• Clinical Trial of Efficacy and Safety of Levopront® 30 mg/5 ml in Patients With Dry CoughCompletedNCT03837938Phase 3Results posted
• Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy VolunteersCompletedNCT03836859Phase 1Results posted
• A Study to Assess Efficacy and Tolerability of Ketoprofen 40 mg Granules vs PlaceboCompletedNCT03836807Phase 3Results posted
• A 8 Weeks Study to Evaluate Efficacy & Safety of rhNGF vs Vehicle in Patients After Cataract and Refractive SurgeryCompletedNCT03035864Phase 2Results posted
• Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver TransplantationTerminatedNCT03031470Phase 2Results posted
• Safety and Efficacy of 2 Concentrations of Lubricin vs Sodium Hyaluronate in Ocular Discomfort After Refractive Surgery.CompletedNCT03031327Not applicableResults posted
• An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry EyeCompletedNCT03019627Phase 2Results posted
• Crossover, Single Dose, Two-stage Bioequivalence Study of SCMC-Lys Salt 1.35 g Powder vs SCMC-Lys Salt 90 mg/mL SyrupCompletedNCT02858193Phase 1Results posted
• Study to Evaluate Safety and Efficacy of rhNGF Eye Drops Solution Versus Vehicle in Patients With GlaucomaCompletedNCT02855450Phase 1Results posted
• A Phase 2, Multicentre, Randomized, Double-blind, Placebo-controlled Study in Patients With New-onset Type 1 DiabetesCompletedNCT02814838Phase 2Results posted
• Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry EyeCompletedNCT02510235Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry EyeCompletedNCT02507934Not applicableResults posted
• A Double-blind Study of Paclitaxel in Combination With Reparixin or Placebo for Metastatic Triple-Negative Breast CancerCompletedNCT02370238Phase 2Results posted
• Crossover, Single Dose Randomized, Bioequivalence of Ketoprofen Lysine Salt Immediate Release vs Oral SolutionCompletedNCT02350296Phase 1Results posted
• Evaluation of Efficacy of 20 µg/ml rhNGF New Formulation (With Anti-oxidant) in Patients With Stage 2 and 3 NKCompletedNCT02227147Phase 2Results posted
• A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)CompletedNCT02110225Phase 1/2Results posted
• Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry EyeCompletedNCT02101281Phase 2Results posted
• Pilot Study to Evaluate Reparixin With Weekly Paclitaxel in Patients With HER 2 Negative Metastatic Breast Cancer (MBC)CompletedNCT02001974Phase 1Results posted
• Efficacy and Safety of Reparixin in Pancreatic Islet Auto-transplantationCompletedNCT01967888Phase 2/3Results posted
• Pilot Study to Evaluate Safety & Biological Effects of Orally Administered Reparixin in Early Breast CancerTerminatedNCT01861054Phase 2Results posted
• Study to Assess Efficacy & Safety of Reparixin in Pancreatic Islet TransplantationCompletedNCT01817959Phase 3Results posted
• Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.CompletedNCT01756456Phase 1/2Results posted
• Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy VolunteersCompletedNCT01744704Phase 1Results posted
• Reparixin in Pancreatic Islet TransplantationCompletedNCT01220856Phase 2Results posted
• Reparixin in Prevention of Delayed Graft Function After Kidney TransplantationCompletedNCT00248040Phase 2Results posted
• Repertaxin in Prevention of Primary Graft Dysfunction After Lung TransplantationCompletedNCT00224406Phase 2Results posted
• Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic KeratitisWithdrawnNCT06411145Phase 4
• Study to Evaluate Corneal Neurosensory Abnormalities in Patients With Sjögren's Dry EyeTerminatedNCT06411132
• To Assess Efficacy and Safety of Oral Reparixin in Patients With Fatigue and Locally Advanced / Metastatic Breast CancerWithdrawnNCT05212701Phase 2
• Ladarixin as Adjunctive Therapy to Improve Insulin Sensitivity and Glucometabolic Outcomes in Type 1 DiabetesWithdrawnNCT05035368Phase 2
• Pilot Efficacy and Safety Study of Oral DF2156A in Patients With Active Bullous PemphigoidTerminatedNCT01571895Phase 2

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