Our grouping. This page groups the registry's lead sponsor names by company — our grouping, not the registry's. It can be wrong or incomplete: an acquired company whose name never mentions its owner may be missing. Use “Something wrong?” under any name below to correct it.
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Cytokinetics clinical trials
The registry lists 41 studies whose lead sponsor is Cytokinetics. 3 are recruiting or about to start. Per ClinicalTrials.gov, last updated Oct 13, 2026.
Keep track of what changes. Save the Cytokinetics studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesRegistry sponsor names on this page
Each name exactly as ClinicalTrials.gov lists it, and how it relates to Cytokinetics.
- Cytokinetics41 studiesSame company
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Focus areas
Conditions Cytokinetics leads ten or more studies in, by study count. A broader condition is left out when almost all its studies are already in a narrower one listed here.
Studies
Recruiting first, then most recently updated. Showing 41 of 41.
- Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection FractionRecruitingNCT06736574Phase 3
- Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCMEnrolling by invitationNCT04848506Phase 2/3
- AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEFRecruitingNCT06793371Phase 2
- A Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)Active, not recruitingNCT06081894Phase 3
- A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).Active, not recruitingNCT06412666Phase 2/3
- Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCMCompletedNCT05767346Phase 3
- Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCMCompletedNCT05186818Phase 3
- Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic CardiomyopathyCompletedNCT04219826Phase 2
- A Single and Multiple Ascending Dose Study of CK-4021586 in Healthy Adult ParticipantsCompletedNCT05877053Phase 1
- Study to Assess the Effect of Omecamtiv Mecarbil (OM) on QT/QTc Intervals in Healthy AdultsCompletedNCT04175808Phase 1
- A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult SubjectsCompletedNCT03767855Phase 1
- A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04944784Phase 3
- A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult ParticipantsTerminatedNCT05662215Phase 1
- A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031)TerminatedNCT05442775Phase 3
- Study to Evaluate the Effect of Aficamten Administration on QT/QTc IntervalCompletedNCT05924815Phase 1
- Study to Assess the Effect of Omecamtiv Mecarbil on Exercise Capacity in Subjects With Heart FailureCompletedNCT03759392Phase 3
- Registrational Study With Omecamtiv Mecarbil (AMG 423) to Treat Chronic Heart Failure With Reduced Ejection FractionCompletedNCT02929329Phase 3
- COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart FailureCompletedNCT01786512Phase 2
- Pharmacokinetics Study of AMG 423 in Healthy Subjects and Subjects With Various Degrees of Renal InsufficiencyCompletedNCT01737866Phase 1
- Pharmacokinetic Study of Omecamtiv Mecarbil in Heart Failure PatientsWithdrawnNCT01077167Phase 2
- Omecamtiv Mecarbil Post-trial Access StudyWithdrawnNCT04464525Phase 3
- Safety, PK, and Efficacy of Omecamtiv Mecarbil in Japanese Subjects With Heart Failure With Reduced Ejection FractionCompletedNCT02695420Phase 2
- Pharmacokinetics and Safety Study of Omecamtiv Mecarbil in Healthy Japanese AdultsCompletedNCT02601001Phase 1
- Study to Evaluate the Safety and Efficacy of IV Infusion Treatment With Omecamtiv Mecarbil in Subjects With Left Ventricular Systolic Dysfunction Hospitalized for Acute Heart Failure (ATOMIC-AHF)CompletedNCT01300013Phase 2
- A Study for Patients Who Completed VITALITY-ALS (CY 4031)CompletedNCT02936635Phase 3
- A Study of CK-1827452 Infusion in Stable Heart FailureCompletedNCT00624442Phase 2
- A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT03160898Phase 2
- Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a YearCompletedNCT02496767Phase 3
- A Study of CK-2127107 in Patients With Spinal Muscular AtrophyCompletedNCT02644668Phase 2
- Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01709149Phase 2
- Phase II Study of the Effect of CK-1827452 Injection on Myocardial EfficiencyTerminatedNCT00748579Phase 2
- A Study of SB-743921 in Non-Hodgkin Lymphoma and Hodgkin LymphomaCompletedNCT00343564Phase 1/2
- Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia GravisTerminatedNCT01268280Phase 2
- A Study of CK-2017357 in Patients With Peripheral Artery Disease and Symptomatic ClaudicationCompletedNCT01131013Phase 2
- A Study of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01089010Phase 2
- A Study to Evaluate the Effects of Multiple Doses of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01378676Phase 2
- A Study of Ispinesib in Metastatic Breast CancerTerminatedNCT00607841Phase 1
- Dose Titration Study to Test Safety and Effects of CK-2017357 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01486849Phase 2
- PK and Tolerability of IV and Oral CK-1827452 in Patients With Ischemic Cardiomyopathy and AnginaCompletedNCT00682565Phase 2
- A Pharmacokinetic and Pharmacodynamic Study of Omecamtiv Mecarbil in Healthy VolunteersCompletedNCT01380223Phase 1
- Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart FailureCompletedNCT00941681Phase 2