City of Hope Medical Center: all 674 studies

Page 2 of 7. Open to participants first (178), then studies with results posted, then the rest; newest registration first within each.

• Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell TransplantRecruitingNCT06543381Phase 1
• Telehealth Intervention for Ostomy Self-ManagementRecruitingNCT06528990Phase 2
• Telehealth Self-Management Coaching Sessions to Improve Quality of Life in Pancreatic Cancer Survivors and Their Family Care GiversRecruitingNCT06524973Not applicable
• Denosumab for Type 1 DiabetesRecruitingNCT06524960Phase 1/2
• Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell TransplantRecruitingNCT06498973Phase 1
• Predicting Peripheral Neuropathy of Paclitaxel for Gastric CancerRecruitingNCT06490159
• Predicting Postoperative Chemotherapy Efficacy in Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT06490003
• Predicting Early Tumor Recurrence in Patients With Esophageal Squamous Cell CarcinomaRecruitingNCT06476067
• Gemcitabine and Leflunomide in Patients With Advanced Unresectable Pancreatic CancerRecruitingNCT06454383Phase 1
• Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular LymphomaRecruitingNCT06453044Phase 2
• Vemurafenib and Cobimetinib for the Treatment of Patients With High Risk Differentiated Thyroid Carcinoma With BRAFV600E MutationRecruitingNCT06440850Phase 2
• Risk Assessment Evaluation for Identifying Participants at High Risk for Stomach CancerRecruitingNCT06408220Not applicable
• Pancreatic Cancer Detection ConsortiumRecruitingNCT06388967
• Early Detection of Advanced Adenomas and Colorectal CancerRecruitingNCT06342440
• An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver CancerRecruitingNCT06342414
• Early Onset Colorectal Cancer DetectionRecruitingNCT06342401
• Stage II/III Colorectal Cancer RecurrenceRecruitingNCT06314958
• 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic SyndromeRecruitingNCT06287944Phase 1
• Stereotactic Body Radiation Therapy and FES PET/CT Imaging for the Treatment of Oligoprogressive Estrogen Receptor Positive Metastatic Breast CancerRecruitingNCT06260033Phase 2
• CMV-specific HIV-CAR T Cells as Immunotherapy for HIV/AIDSRecruitingNCT06252402Early Phase 1
• Carfilzomib in Combination With Sotorasib for the Treatment of Patients With KRAS G12C Mutated Advanced or Metastatic Non-small Cell Lung CancerRecruitingNCT06249282Phase 1
• Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their CaregiversRecruitingNCT06196008Not applicable
• Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation TherapyRecruitingNCT06139627Not applicable
• Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic SyndromeRecruitingNCT06128070Phase 2
• CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell TransplantRecruitingNCT06059391Phase 2
• Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell LymphomaRecruitingNCT06054776Phase 2
• Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART StudyRecruitingNCT06052826Phase 2
• Mezigdomide (CC-92480) Post Idecabtagene Vicleucel in Treating Patients With Relapsed Multiple MyelomaRecruitingNCT06048250Phase 1
• Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY TrialRecruitingNCT06042569Phase 2
• Telemedicine for Improvement of Care for Older Adults With Cancer in the Underserved Community, The GAIN-S TrialRecruitingNCT06022965Not applicable
• Bright White Light Therapy in Reducing Cancer-Related Fatigue and Depression in Advanced Prostate Cancer Patients Undergoing Treatment With ADT Combination TherapyRecruitingNCT05869682Phase 2
• Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell LymphomaRecruitingNCT05861050Phase 1/2
• Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell CarcinomaRecruitingNCT05830058Phase 2
• PSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate CancerRecruitingNCT05805371Phase 1
• Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) for the Treatment of Intermediate or High Grade B-Cell Non-Hodgkin LymphomaRecruitingNCT05801913Phase 1
• Evaluation of Bridging Radiation Therapy Before CAR T-Cell Infusion for the Treatment of Relapsed or Refractory Large B-Cell LymphomaRecruitingNCT05800405Early Phase 1
• Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE StudyRecruitingNCT05772130Not applicable
• A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic AnemiaRecruitingNCT05757310Phase 1
• A Study on the Effects of Exercise Therapy on Signs of Prostate CancerRecruitingNCT05751434Phase 2
• Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid TumorsRecruitingNCT05733949Early Phase 1
• The da Vinci Single Port Robotic System for Use in Abdominal and Pelvic Surgical ProceduresRecruitingNCT05672368Phase 2
• Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell LymphomaRecruitingNCT05672251Phase 2
• CD33-CAR T Cell Therapy for the Treatment of Recurrent or Refractory Acute Myeloid LeukemiaRecruitingNCT05672147Phase 1
• Phase II Trial of Lung ChemoemobolizationRecruitingNCT05672108Phase 2
• Intracerebroventricular Administration of CD19-CAR T Cells (CD19CAR-CD28-CD3zeta-EGFRt-expressing Tn/Mem T-lymphocytes) for the Treatment of Central Nervous System LymphomaRecruitingNCT05625594Phase 1
• Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary CancersRecruitingNCT05519878Not applicable
• Circulating Biomarkers in the Development of Type 1 DiabetesRecruitingNCT05505669
• Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic MalignanciesRecruitingNCT05443425Phase 1
• Genetically Modified T-cells (CMV-Specific CD19-CAR T-cells) Plus a Vaccine (CMV-MVA Triplex) Following Stem Cell Transplantation for the Treatment of Intermediate or High Grade B-cell Non-Hodgkin LymphomaRecruitingNCT05432635Phase 1
• An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain MetastasisRecruitingNCT05376878Phase 4
• Study to Evaluate CD8 PET Imaging as a Marker of Immune Response to Stereotactic Body Radiation Therapy (ELIXR)RecruitingNCT05371132Phase 1
• Radioimmunotherapy (111Indium/225Actinium-DOTA-daratumumab) for the Treatment of Relapsed/Refractory Multiple MyelomaRecruitingNCT05363111Phase 1
• Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal MetastasesRecruitingNCT05285358Phase 1
• Evaluation of DNA Methylation Signatures for the Diagnosis and Management of Thyroid NodulesRecruitingNCT05229341Not applicable
• AOH1996 for the Treatment of Refractory Solid TumorsRecruitingNCT05227326Phase 1
• Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian CancerRecruitingNCT05225363Phase 1
• Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic CancersRecruitingNCT05204147Phase 1
• Multiple Intracerebral Doses of Neural Stem Cell-Based Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade GliomasRecruitingNCT05139056Phase 1
• Radiotherapy in Combination With Atezolizumab in Locally Advanced Borderline Resectable or Unresectable Cutaneous SCCRecruitingNCT05085496Phase 1
• Extracorporeal Photopheresis and Mogamulizumab for the Treatment of Erythrodermic Cutaneous T Cell LymphomaRecruitingNCT04930653Phase 2
• Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast CancerRecruitingNCT04913064Not applicable
• Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin LymphomaRecruitingNCT04871607Phase 2
• Study to Detect Changes in Urinary and Gut Microbiome During Androgen Deprivation Therapy and Radiation Therapy in Patients With Prostate CancerRecruitingNCT04775355
• Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate CancerRecruitingNCT04734730Phase 2
• Quality of Life in Cutaneous Lymphoma Patients Using the Skindex29RecruitingNCT04670874
• Researching the Effect of Exercise on CancerRecruitingNCT04589468Not applicable
• Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin LymphomaRecruitingNCT04561206Phase 2
• CAR T Cells After Lymphodepletion for the Treatment of IL13Rα2 Positive Recurrent or Refractory Brain Tumors in ChildrenRecruitingNCT04510051Phase 1
• Leflunomide, Pomalidomide, and Dexamethasone for the Treatment of Relapsed or Refractory Multiple MyelomaRecruitingNCT04508790Phase 2
• PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
• Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.RecruitingNCT04305834Phase 2
• Molecular Genetics Studies of Cancer Patients and Their RelativesRecruitingNCT04185935
• Biospecimen Analysis in Detecting Chemical Concentrations in Patients With Chronic or Infectious Diseases Receiving MeditationsRecruitingNCT04160429
• Improving Islet Transplantation Outcomes With Gastrin for Type I DiabetesRecruitingNCT03746769Phase 1/2
• Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid NodulesRecruitingNCT03676647
• Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell LymphomaRecruitingNCT03523975Phase 1/2
• Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell TransplantRecruitingNCT03354728Phase 1/2
• Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell LymphomaRecruitingNCT03011814Phase 1/2
• RefleXion PET/CT Imaging Performance in Patients With Prostate CancerActive, not recruitingNCT05470699Not applicableResults posted
• Perioperative Telemonitoring to Optimize Cancer Care and OutcomesActive, not recruitingNCT04986566Not applicableResults posted
• Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction CancerActive, not recruitingNCT04929392Phase 2Results posted
• HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of GenomicsActive, not recruitingNCT04905082Not applicableResults posted
• Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell LymphomaActive, not recruitingNCT04783415Phase 2Results posted
• Polatuzumab Vedotin, Rituximab, Ifosfamide, Carboplatin, and Etoposide (PolaR-ICE) as Initial Salvage Therapy for the Treatment of Relapsed/Refractory Diffuse Large B-Cell LymphomaActive, not recruitingNCT04665765Phase 2Results posted
• Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic LeukemiaActive, not recruitingNCT04657094Phase 2Results posted
• Home Base Telemonitoring in Gastrointestinal, Genitourinary, or Gynecologic Cancer Patients Undergoing Abdominal SurgeryActive, not recruitingNCT04596384Not applicableResults posted
• Leflunomide for the Treatment of Severe COVID-19 in Patients With a Concurrent MalignancyCompletedNCT04532372Phase 1/2Results posted
• Leflunomide for the Treatment of Relapsed or Refractory CD30+ Lymphoproliferative DisordersCompletedNCT04463615Phase 2Results posted
• Itacitinib, Tacrolimus, and Sirolimus for the Prevention of GVHD in Patients With Acute Leukemia, Myelodysplastic Syndrome, or Myelofibrosis Undergoing Reduced Intensity Conditioning Donor Stem Cell TransplantationCompletedNCT04339101Phase 2Results posted
• Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue SarcomaActive, not recruitingNCT04200443Phase 2Results posted
• Triplex Vaccine in Preventing CMV Infection in Patients Undergoing Hematopoietic Stem Cell TransplantationActive, not recruitingNCT04060277Phase 2Results posted
• Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaActive, not recruitingNCT03961672Phase 2Results posted
• IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction CancerCompletedNCT03918499Phase 1/2Results posted
• PSCA-CAR T Cells in Treating Patients With PSCA+ Metastatic Castration Resistant Prostate CancerActive, not recruitingNCT03873805Phase 1Results posted
• Ipatasertib in Combination With Carboplatin, Carboplatin/Paclitaxel, or Capecitabine/Atezolizumab in Treating Patients With Metastatic Triple Negative Breast CancerCompletedNCT03853707Phase 1/2Results posted
• Conquer Fear SUPPORT Intervention in Supporting Patients With Stage III-IV Lung or Gynecologic CancerCompletedNCT03776253Not applicableResults posted
• Multimedia Self-Management Intervention for Lung Cancer Surgery Family Caregivers and PatientsActive, not recruitingNCT03686007Not applicableResults posted
• Megestrol Acetate With or Without Pterostilbene in Treating Patients With Endometrial Cancer Undergoing HysterectomyActive, not recruitingNCT03671811Phase 2Results posted
• Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell LymphomasActive, not recruitingNCT03598998Phase 1/2Results posted
• CMV-MVA Triplex Vaccination of Stem Cell Donors in Preventing CMV Viremia in Participants With Allogeneic TransplantActive, not recruitingNCT03560752Phase 1Results posted

← City of Hope Medical Center overview and focus areas