Medulloblastoma: all 242 studies
Page 1 of 3. Open to participants first (52), then studies with results posted, then the rest; newest registration first within each.
- Study of CDK8 Inhibitor RVU120 in Combination With Everolimus in Children With Recurrent or Progressive Group 3 or 4 MedulloblastomaNot yet recruitingNCT07865130Phase 1
- Arsenic Trioxide Combined With Chemotherapy for Relapsed SHH-Activated and/or TP53-Mutant MedulloblastomaNot yet recruitingNCT07856069Phase 2
- Cognitive Rehabilitation for Survivors of Childhood Medulloblastoma Using Real Time Hemodynamic NeurofeedbackRecruitingNCT07830134Not applicable
- AI-Assisted MRI Molecular Subtyping in Pediatric Brain TumorsNot yet recruitingNCT07703605
- A Study of 177Lu-DTPA-Omburtamab in Children and Adolescents With Brain Cancer or Cancer That Has Spread to the Central Nervous System (CNS)RecruitingNCT07698899Phase 1
- Targeting MYC in High-Risk MedulloblastomaNot yet recruitingNCT07694622Not applicable
- Safety and Efficacy of Vertebral Body-Sparing Craniospinal Irradiation With Proton Therapy in Pediatric TumorsNot yet recruitingNCT07589361
- Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid TumorsRecruitingNCT07584499Phase 1
- my.naviGATE: A Guide to After-Treatment Effects for Adolescents and Young AdultsNot yet recruitingNCT07516353Not applicable
- B7-H3.CD28Z.CART in CNS NeoplasmsRecruitingNCT07390539Phase 1
- Liothyronine in Combination With BIT Regimen for Medulloblastoma With or Without Minimal Residual DiseaseRecruitingNCT07346157Phase 1/2
- Comparison of Neurocognitive Outcome in Two Standard Regimen for Treatment of Low-risk MedulloblastomaNot yet recruitingNCT07291102Phase 3
- Relapsed and Progressive Sonic Hedgehog Medulloblastoma With U1 Mutation Registry StudyRecruitingNCT07242963
- GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young AdultsRecruitingNCT07087002Phase 1
- CSIMEMPHIS: Long-term Follow-up of Medulloblastoma Survivors That Received Craniospinal IrradiationRecruitingNCT07085325
- Novel Molecular Targets and Innovative Therapeutic Perspective in MedulloblastomaRecruitingNCT06959979Early Phase 1
- Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post ConsolidationRecruitingNCT06942039Early Phase 1
- Medulloblastoma Online Video-based Exercise Pilot StudyRecruitingNCT06898684Not applicable
- Intraoperatively Observed Site of Origin and Growth Pattern of MedulloblastomaEnrolling by invitationNCT06814353
- Pharmacoscopy for Patients With Refractory Primary Brain TumorsRecruitingNCT06804655Phase 2
- Systemic Biomarkers to Predict Radiation-Induced Neurocognitive DeclineRecruitingNCT06779487
- Digoxin Medulloblastoma StudyRecruitingNCT06701812Phase 2
- Atovaquone Combined With Radiation in Children With Malignant Brain TumorsRecruitingNCT06624371Phase 1
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/2
- Adoptive T Cell Therapy, DC Vaccines, and Hematopoietic Stem Cells Combined With Immune checkPOINT Blockade in Patients With MedulloblastomaRecruitingNCT06514898Phase 1
- In Vitro Models From Pediatric Brain TumorsNot yet recruitingNCT06499636
- Axitinib and Oral Metronomic Etoposide for Pediatric Children and AYA Refractory/Relapsing Medulloblastoma and EpendymomaNot yet recruitingNCT06485908Phase 1/2
- Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant GliomaNot yet recruitingNCT06396481Early Phase 1
- Integrated Analysis of Therapy Response and Resistence in Embryonal Tumors and GliomasNot yet recruitingNCT06323408
- Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)RecruitingNCT06193759Phase 1
- PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN AmplificationsRecruitingNCT06161519Phase 1/2
- Horse Therapy for Children, Adolescents and Young Adults in Remission From MedulloblastomaRecruitingNCT05755295Not applicable
- Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in ChinaRecruitingNCT05672043
- Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed MedulloblastomaRecruitingNCT05535166Phase 2
- Establishment and Clinical Application of Risk Classification Model Based on Molecular Typing of Medulloblastoma in ChildrenNot yet recruitingNCT05406947
- A Study of Treatment for Medulloblastoma Using Sodium Thiosulfate to Reduce Hearing LossRecruitingNCT05382338Phase 3
- GD2-CAR T Cells for Pediatric Brain TumoursRecruitingNCT05298995Phase 1
- Lutathera for Treatment of Recurrent or Progressive High-Grade CNS TumorsRecruitingNCT05278208Phase 1/2
- Effect of Metformin on Behaviour and the Brain in Children Treated for a Brain TumourRecruitingNCT05230758Phase 3
- Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain CancerRecruitingNCT05106296Phase 1
- PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent MedulloblastomaRecruitingNCT05096481Phase 2
- Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and EpendymomaRecruitingNCT05057702Not applicable
- DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed MedulloblastomaRecruitingNCT04696029Phase 2
- Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsRecruitingNCT04541082Phase 1
- Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in ChildrenRecruitingNCT04501718Phase 2
- Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.RecruitingNCT04474964Not applicable
- Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System TumorsRecruitingNCT04185038Phase 1
- 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.RecruitingNCT04081701Phase 4
- HSV G207 in Children With Recurrent or Refractory Cerebellar Brain TumorsRecruitingNCT03911388Phase 1
- An Intermediate Expanded Use Trial of DFMOAvailableNCT03581240
- International HIT-MED Registry (I-HIT-MED)RecruitingNCT02417324
- Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS TumorsRecruitingNCT01356290Phase 2
- Fluorescence Detection of Adult Primary Central Nervous System Tumors With Tozuleristide and the Canvas SystemCompletedNCT04743310Phase 2Results posted
- A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant CancerTerminatedNCT04730349Phase 1/2Results posted
- Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04320888Phase 2Results posted
- Tipifarnib for the Treatment of Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With HRAS Gene Alterations, a Pediatric MATCH Treatment TrialActive, not recruitingNCT04284774Phase 2Results posted
- A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaCompletedNCT04238819Phase 1/2Results posted
- Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT04195555Phase 2Results posted
- 177Lu-DTPA-Omburtamab Radioimmunotherapy for Recurrent or Refractory MedulloblastomaTerminatedNCT04167618Phase 1/2Results posted
- Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have SurgeryTerminatedNCT03904862Phase 1/2Results posted
- Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid TumorsCompletedNCT03709680Phase 2Results posted
- Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03698994Phase 2Results posted
- Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent MedulloblastomaCompletedNCT03615404Phase 1Results posted
- Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS TumorsActive, not recruitingNCT03598244Phase 1Results posted
- Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03526250Phase 2Results posted
- Phase I Study of APX005M in Pediatric Central Nervous System TumorsCompletedNCT03389802Phase 1Results posted
- Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain TumorsCompletedNCT03387020Phase 1Results posted
- Dosimetry-Guided, Peptide Receptor Radiotherapy (PRRT) With 90Y-DOTA- tyr3-Octreotide (90Y-DOTATOC)CompletedNCT03273712Phase 2Results posted
- A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain TumorsCompletedNCT03257631Phase 2Results posted
- Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)CompletedNCT03233204Phase 2Results posted
- Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03213704Phase 2Results posted
- Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213678Phase 2Results posted
- Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations (A Pediatric MATCH Treatment Trial)CompletedNCT03213665Phase 2Results posted
- Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03213652Phase 2Results posted
- Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)Active, not recruitingNCT03210714Phase 2Results posted
- Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS CancersTerminatedNCT03173950Phase 2Results posted
- Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)Active, not recruitingNCT03155620Phase 2Results posted
- Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in ChildrenCompletedNCT03043391Phase 1Results posted
- Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)TerminatedNCT02624388Phase 2Results posted
- Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine TumorsCompletedNCT02441062Phase 2Results posted
- Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETsTerminatedNCT02332889Phase 1/2Results posted
- Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System TumorsTerminatedNCT02255461Phase 1Results posted
- Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive MedulloblastomaTerminatedNCT02212574Early Phase 1Results posted
- Molecular-Guided Therapy for Childhood CancerCompletedNCT02162732Not applicableResults posted
- Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT02095132Phase 1/2Results posted
- Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic MedulloblastomaCompletedNCT02017964Phase 2Results posted
- Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With CancerTerminatedNCT01987596Phase 3Results posted
- Plerixafor After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed High Grade GliomaCompletedNCT01977677Phase 1/2Results posted
- Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CTCompletedNCT01869725Phase 2Results posted
- Molecular-Guided Therapy for Relapsed and Refractory Childhood CancerCompletedNCT01802567Not applicableResults posted
- A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB)CompletedNCT01708174Phase 2Results posted
- Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid TumorsCompletedNCT01619865Phase 1/2Results posted
- Concurrent Carboplatin and Reduced Dose Craniospinal Radiation for Medulloblastoma and Primitive Neuroectodermal Tumor (PNET)CompletedNCT01542736Phase 2Results posted
- Safety and Efficacy Study of TPI-287 in Neuroblastoma and MedulloblastomaTerminatedNCT01483820Phase 1/2Results posted
- Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal TumorCompletedNCT01326104Phase 2Results posted
- Vismodegib in Treating Younger Patients With Recurrent or Refractory MedulloblastomaCompletedNCT01239316Phase 2Results posted
- Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal TumorsCompletedNCT01217437Phase 2Results posted
- A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MBCompletedNCT01125800Phase 1/2Results posted
- Proton Beam Radiotherapy for Medulloblastoma and PineoblastomaCompletedNCT01063114Not applicableResults posted
- Vismodegib in Treating Patients With Recurrent or Refractory MedulloblastomaCompletedNCT00939484Phase 2Results posted