Chiesi Farmaceutici S.p.A.: all 299 studies

Page 1 of 3. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.

• A Study to Assess the Safety, Tolerability and Pharmacokinetics of Repeated Doses of Inhaled CHF10073 in Participants With Idiopathic Pulmonary FibrosisNot yet recruitingNCT07876284Phase 1
• Safety and Efficacy Comparison Between CHF5993 100/6 12.5µg pMDI to Seretide Evohaler 125/25µg pMDI in Adolescent Subjects With AsthmaNot yet recruitingNCT07858123Phase 3
• Evaluation of Safety, Side Effects, and How the Drug, Inhaled CHF10136, Is Absorbed, Modified and Removed From the Body in Healthy Adults and Adults With AsthmaRecruitingNCT07851623Phase 1
• A Study in Healthy Male Participants to Compare How CHF10196 Affects How the Body Absorbs and Processes Two Commonly Used Medicines: Dabigatran, a Blood Thinner, and Rosuvastatin, a Medicine Used to Lower CholesterolNot yet recruitingNCT07744386Phase 1
• A Study to Compare How CHF10196 (Florensocatib) is Absorbed Into the Blood When Given Alone and With a Drug That Reduces Stomach Acid in Healthy Male ParticipantsNot yet recruitingNCT07683793Phase 1
• BETRI-Prospective: Asthma Control in Single Inhaler ICS/LABA/LAMA (87/5/9 pMDI [BDP/FF/GB - 100/6/12.5 μg]) vs Single Inhaler ICS/LABA (200/6 pMDI [BDP/FF - 200/6 μg])RecruitingNCT07666490Phase 4
• Safety and Effectiveness of Sebetralstat (KVD900) for Short-Term Prophylaxis Before Procedures in People With Hereditary Angioedema (KONTROL)RecruitingNCT07654829Phase 4
• A Study to Evaluate the Efficacy and Safety of CHF10196 Tablets (Florensocatib) Compared With Placebo in Male and Female Participants 12 to 85 Years of Age With BronchiectasisNot yet recruitingNCT07577804Phase 3
• Efficacy and Safety of CHF 5993 100/6/12.5 μg HFA-152a pMDI in Patients With Asthma Uncontrolled on Medium Doses of Inhaled Corticosteroids in Combination With Long-acting ß2-agonistsRecruitingNCT07546981Phase 3
• A Study to Find an Efficacious and Safe Dose of CHF10067 (Zampilimab) in Participants With Idiopathic Pulmonary FibrosisRecruitingNCT07516951Phase 2
• Fixed Triple Inhaled Combination in Asthmatic Patients in a Real-life Setting (STRENGTH)RecruitingNCT07489911
• Real-World Effectiveness of a Triple Combination BDP/FF/GB Extrafine in a Single Pressurised Metered Dose Inhaler in Brazilian COPD PatientsRecruitingNCT07406048
• Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate AsthmaRecruitingNCT07301736Phase 2
• Treatment of Angioedema Attacks in Pediatric (Ages 2-11) Post-Trial and Naive Patients With HAE With SebetralstatAvailableNCT07216378
• Evaluation of Safety, Side Effects and How the Drug CHF6467 Administered Via Intranasal Route is Absorbed, Modified and Removed in Healthy SubjectsRecruitingNCT07163182Phase 1
• Observational Study on Long-term Use of Pegunigalsidase Alfa in Fabry Patients in a Real-world SettingRecruitingNCT07109375
• Bedside Ultrasound to Monitor Lung Function and Blood Flow in Newborns Treated With SurfactantNot yet recruitingNCT07070167
• Real-word Study of the de NOVO Extended-release tacrolimuS in Kidney Transplantation Using an ARTificial IntelligenceNot yet recruitingNCT06960824
• Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and BreastfeedingRecruitingNCT06941025
• A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis BullosaRecruitingNCT06917690Phase 3
• Efficacy of a Smart add-on Device in Combination With a Triple Treatment in Asthma Patients on Inhaler Technique and AdherenceRecruitingNCT06908421
• The Importance of Tailored Education And Device Handling for Asthmatic PatientsNot yet recruitingNCT06840522
• Tacrolimus and Risk Factors for Glucose Metabolism Disorders in Kidney Transplant PatientsRecruitingNCT06833463
• Utilising Hull Lung Health Study Data to Investigate the Performance of TidalSense Diagnostic Algorithms to Identify COPD and Pre-COPD Among Participants in the FRONTIER Programme.Not yet recruitingNCT06788613
• Open-label Extension Study to Evaluate Metreleptin in Patients With Partial LipodystrophyRecruitingNCT06679270Phase 3
• Investigation of Fixed Triple Inhaled Combination in Asthmatic Patients, in a Real-life SettingRecruitingNCT06678191
• A Multi-Country Observational Study of Safety and Effectiveness of Elfabrio® in Fabry PatientsRecruitingNCT06663358
• TriMaximize: A Multicentre, Prospective, Non-interventional Trial in Asthma PatientsRecruitingNCT06567977
• Open-label Study to Evaluate Metreleptin in Patients With Partial LipodystrophyRecruitingNCT06484868Phase 4
• A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving FilsuvezRecruitingNCT06423573
• A Study to Learn About the Safety and Effects of the Study Drug PRX-102 in Children and Adolescents With Fabry DiseaseRecruitingNCT06328608Phase 2/3
• Analysis of Velmanase Alfa (Lamzede®)'s Effects in the Body of Children With Alpha-Mannosidosis Under the Age 3RecruitingNCT06184503
• Impact of Fixed TRIple Therapy With Beclometasone/Formoterol/Glycopyrronium DPI (Trimbow® in NEXThaler Device) in Chronic Obstructive PulmoNary Disease in rEal-world Settings: Health-related Quality of Life Patient' eXpectations and characterisTics: the TriNEXT StudyRecruitingNCT05948891
• Assessment of the Pharmacokinetic Profile of Tacrolimus Medications and Their Relation to Effectiveness and Safety in Liver Transplant PatientsRecruitingNCT05744635
• A Multicentre, Prospective, Non-interventional Trial Monitoring Therapy Pathways of Asthma Patients Treated With an Extra-fine ICS/LABA/LAMA Single-inhaler Triple Therapy in a Real-world Setting and Characterizing the Effects on Health-related OutcomesRecruitingNCT05728749
• Study to Evaluate the Safety, PK, PD, and Efficacy of PRX-102 in Japanese Patients With Fabry DiseaseRecruitingNCT05710692Phase 2/3
• PASS to Assess Cardiovascular and Cerebrovascular Events in COPD Patients Initiating Fixed Triple Therapy (DPI or pMDI)RecruitingNCT05652439
• Expanded Access to Velmanase AlfaAvailableNCT04959240
• MEASuRE: Metreleptin Effectiveness And Safety RegistryRecruitingNCT02325674
• Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or IICompletedNCT06467084Phase 3Results posted
• Study to Assess the Effect of the New HFA-152a Propellant on Mucociliary ClearanceCompletedNCT05875025Phase 1Results posted
• A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Monoclonal Antibody (mAb) in Patients With IPF (SAD).CompletedNCT05513950Phase 1Results posted
• A Study to Compare the Effects of Two Propellants in Adults With Mild AsthmaCompletedNCT05472662Phase 2Results posted
• A Study Testing the Superiority of CHF 1535 pMDI 800/24µg Total Daily Dose Compared With CHF 718 pMDI 800µg Total Daily Dose in Adults With Asthma on Medium or High-Dose Inhaled CorticosteroidCompletedNCT05292586Phase 3Results posted
• A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)CompletedNCT05259917Phase 3Results posted
• A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or IITerminatedNCT05055258Phase 2Results posted
• Study in Adult Patients With Moderate to Severe AsthmaCompletedNCT04886999Phase 3Results posted
• Functional Respiratory Imaging Study (DARWiIN)CompletedNCT04876677Phase 3Results posted
• Evaluation of the Absolute Bioavailability and Mass Balance of CHF6001 (Tanimilast) in Healthy SubjectsCompletedNCT04756960Phase 1Results posted
• Efficacy and Safety of Lomitapide in Paediatric Patients With Homozygous Familial Hypercholesterolaemia (HoFH)CompletedNCT04681170Phase 3Results posted
• Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)TerminatedNCT04502433Phase 2Results posted
• A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or IICompletedNCT04208412Phase 2Results posted
• CHF6563 in Babies With Neonatal Opioid Withdrawal SyndromeTerminatedNCT04104646Phase 2Results posted
• Immunogenicity of Metreleptin in Patients With Generalized LipodystrophyCompletedNCT04026178Phase 4Results posted
• Foster® pMDI (CHF 1535) Versus Symbicort® Turbohaler in COPD Patient (FORSYYN)CompletedNCT03888131Phase 3Results posted
• Registry Study of Revcovi Treatment in Patients With ADA-SCIDCompletedNCT03878069Results posted
• Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron OverloadCompletedNCT03802916Phase 2Results posted
• Efficacy and Safety of CUSA-081 in the Restoration of Central Venous Access Device (CVAD) FunctionalityTerminatedNCT03594175Phase 3Results posted
• Safety and Efficacy of Early Treatment With Deferiprone in Infants and Young ChildrenCompletedNCT03591575Phase 4Results posted
• Open Label Extension Study of 1 mg/kg Pegunigalsidase Alfa Every 2 Weeks in Patients With Fabry DiseaseCompletedNCT03566017Phase 3Results posted
• Study of the Intravitreal Plasma Kallikrein Inhibitor, KVD001, in Subjects With Center-involving Diabetic Macular Edema (ciDME)CompletedNCT03466099Phase 2Results posted
• Foster 100/6 mg NEXThaler Versus Foster 100/6mg Pressurized Metered-dose Inhaler (pMDI) in Patients With Controlled Asthma.CompletedNCT03453112Phase 3Results posted
• Efficacy and Safety of Octreotide Capsules (MYCAPSSA) in AcromegalyStatus unknownNCT03252353Phase 3Results posted
• Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) (TRIVERSYTI)CompletedNCT03197818Phase 3Results posted
• A Dose Ranging Study With CHF 1531 in Subjects With Asthma (FLASH)CompletedNCT03086460Phase 2Results posted
• A 6-week Dose Ranging Study of CHF 5259 pMDI in Subjects With Chronic Obstructive Pulmonary DiseaseCompletedNCT03084796Phase 2Results posted
• An 8-week Dose Ranging Study of CHF 718 pMDI in Asthmatic SubjectsCompletedNCT03084718Phase 2Results posted
• Phase III Efficacy and Safety Study of Oleogel-S10 in Epidermolysis BullosaCompletedNCT03068780Phase 3Results posted
• A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional AdministrationTerminatedNCT02772081Phase 3Results posted
• Study of Parkinson's Early Stage With DeferiproneCompletedNCT02728843Phase 2Results posted
• Comparison of Oral Octreotide Capsules to Injectable Somatostatin Analogs in AcromegalyCompletedNCT02685709Phase 3Results posted
• TRIple in Asthma hiGh strenGth vErsus Ics/Laba hs and tiotRopium (TRIGGER)CompletedNCT02676089Phase 3Results posted
• TRIple in asthMA With uncontRolled pAtient on Medium streNgth of ICS + LABACompletedNCT02676076Phase 3Results posted
• Comparison of Deferiprone Extended Release Tablets and Ferriprox Immediate Release Tablets in Healthy VolunteersCompletedNCT02465489Phase 1Results posted
• A Double Blind, Randomized, Controlled Study to Evaluate CHF 5633 (Synthetic Surfactant) and Poractant Alfa in Neonates With Respiratory Distress Syndrome (RDS) (POC)CompletedNCT02452476Phase 2Results posted
• Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other AnemiasTerminatedNCT02443545Phase 4Results posted
• Comparison of Deferiprone Delayed Release Tablets and Deferiprone Oral Solution in Healthy VolunteersCompletedNCT02442310Phase 1Results posted
• Efficacy of LAMA Added to ICS in Treatment of Asthma (ELITRA)CompletedNCT02296411Phase 2Results posted
• Pilot Study of the Pharmacokinetic Profile of Deferiprone Sustained-Release Formulation in Healthy VolunteersCompletedNCT02189941Phase 1Results posted
• Long-term Deferiprone Treatment in Patients With Pantothenate Kinase-Associated NeurodegenerationCompletedNCT02174848Phase 3Results posted
• Efficacy and Safety of Lomitapide in Japanese Patients With HoFH on Concurrent Lipid-Lowering TherapyCompletedNCT02173158Phase 3Results posted
• Triple in Asthma Dose FindingCompletedNCT02127866Phase 2Results posted
• Evaluate the Effect of Ethinyl Estradiol/Norgestimate on the Pharmacokinetics of Lomitapide in Healthy Female SubjectsCompletedNCT02080468Phase 1Results posted
• Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Lomitapide in Healthy Subjects.CompletedNCT02080455Phase 1Results posted
• A Comparative Bioavailability Study of Lomitapide 20 mg Intact vs SprinkledCompletedNCT02044419Phase 1Results posted
• Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other AnemiasTerminatedNCT02041299Phase 4Results posted
• Effect of OC000459 on Moderate to Severe Atopic DermatitisCompletedNCT02002208Phase 2Results posted
• A Blinded, Placebo-Controlled Study of the Safety and Pharmacokinetics of Single Doses of Intravenous Deferiprone in Healthy VolunteersCompletedNCT01989455Phase 1Results posted
• Assessment of Efficacy, Safety and Dosing of Clevidipine in Pediatric Participants Undergoing Surgery (PIONEER)TerminatedNCT01938547Phase 4Results posted
• Efficacy of Fixed Combination of Beclometasone + Formoterol + Glycopyrrolate Versus Foster® in COPDCompletedNCT01917331Phase 3Results posted
• Study to Determine the Intra-subject Variability of Pharmacokinetics of Lomitapide in Healthy SubjectsCompletedNCT01915771Phase 1Results posted
• Evaluation of Whether Deferiprone Affects QT Interval in Healthy SubjectsCompletedNCT01860703Phase 4Results posted
• Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell DiseaseCompletedNCT01835496Phase 1Results posted
• Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSG-12)CompletedNCT01807650Phase 3Results posted
• Single Dose Bronchodilatory Study in AsthmaCompletedNCT01805687Phase 4Results posted
• An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild, Moderate, Severe, or No Renal ImpairmentCompletedNCT01770652Phase 4Results posted
• An Open-label, Non-randomized, Parallel Group Study in Subjects With Mild and Moderate Hepatic Insufficiency and Healthy VolunteersCompletedNCT01767103Phase 4Results posted
• Phase I Study of the Safety, Tolerability, PK & PD of Lomitapide in Japanese and Caucasian Subjects With Elevated LDL-CCompletedNCT01760187Phase 1Results posted
• Efficacy and Safety Study of Deferiprone in Patients With Pantothenate Kinase-associated Neurodegeneration (PKAN)CompletedNCT01741532Phase 3Results posted
• Oleogel-S10 in Wound Healing of Split-Thickness Skin Graft Donor Sites (BSH-12)CompletedNCT01657305Phase 3Results posted

← Chiesi Farmaceutici S.p.A. overview and focus areas