Brigham and Women's Hospital: Heart Failure trials

The registry lists 33 Heart Failure studies with Brigham and Women's Hospital as lead sponsor. 7 are open to participants now and 5 have results posted.

Phase 2 3Phase 3 2Phase 4 4No phase 24(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• N-of-1 Trial to Promote Beta-Blocker Titration in Heart FailureEnrolling by invitationNCT07489352Not applicable
• CORTISHOCK-P: Trial of Corticosteroids in Inflammation-Enriched Heart Failure Cardiogenic ShockNot yet recruitingNCT07461961Phase 2
• Targeted Artificial Intelligence Language mOdel Recommendations for Heart Failure (TAILOR-HF)RecruitingNCT07337577Not applicable
• Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language ModelsRecruitingNCT06588452
• Care Transitions App for Patients With Multiple Chronic ConditionsRecruitingNCT06051058Not applicable
• Advancing Health Information Exchange (HIE) During Inter-hospital Transfer (IHT) to Improve Patient OutcomesEnrolling by invitationNCT05443321Not applicable
• Home Hospital for Suddenly Ill AdultsRecruitingNCT03524222Not applicable
• Advance Care Planning in the Emergency DepartmentCompletedNCT05209880Not applicableResults posted
• The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep ApneaTerminatedNCT03745898Phase 3Results posted
• Pulmonary Artery Pressure Reduction With ENTresto (Sacubitril/Valsartan)TerminatedNCT02788656Phase 4Results posted
• INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart FailureCompletedNCT02787044Phase 4Results posted
• Intervention With Vitamin D and Omega-3 Supplements and Incident Heart FailureCompletedNCT02271230Phase 3Results posted
• Serum Potassium Prediction Using Machine Learning and Single-lead ECGWithdrawnNCT07493798
• Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)CompletedNCT07390110
• Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection FractionActive, not recruitingNCT06980623
• Augmented Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for PESuspendedNCT06310018
• COPILOT-HF: Cooperative Program for ImpLementation of Optimal Therapy in Heart FailureCompletedNCT05734690Phase 4
• Rural Hospital-Level Care at Home for Acutely Ill AdultsCompletedNCT05256303Not applicable
• Prediction of Patient Deterioration Using Machine LearningCompletedNCT05045742
• Prediction of 30-Day Readmission Using Machine LearningCompletedNCT04849312
• Prediction of Expected Length of Hospital Stay Using Machine LearningWithdrawnNCT04784351
• Prospective Monitoring of Angiotensin Receptor Neprilysin Inhibitor in Older Adults With Heart Failure and FrailtyStatus unknownNCT04743063
• Replication of the PARADIGM-HF Heart Failure Trial in Healthcare Claims Data.CompletedNCT04736433
• Reducing Structural Inequities in Heart Failure Management: An Approach to Improve the Quality of Heart Failure Care on the General Medicine Service: Longitudinal Equity Action Plan (LEAP)CompletedNCT03942978Not applicable
• Comparing ARNI With ACE Inhibitor on Endothelial FunctionWithdrawnNCT03119623Phase 4
• Hospitalization at Home: The Acute Care Home Hospital Program for AdultsCompletedNCT02864420Not applicable
• Focused Palliative Care Intervention in Advanced Heart FailureCompletedNCT02805712Not applicable
• Improving Quality by Maintaining Accurate Problems in the EHRCompletedNCT02596087Not applicable
• Study of an Intervention to Improve Problem List Accuracy and UseStatus unknownNCT01105923Not applicable
• Melatonin Supplementation to Improve Sleep in Patients With Heart FailureWithdrawnNCT00869869Phase 2
• Evaluating the Relationship Between Fatty Acids and Heart DiseaseCompletedNCT00404872
• Ventricular-Vascular Coupling in Heart FailureCompletedNCT00207220
• Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal DysfunctionCompletedNCT00119691Phase 2