Biogen: all 548 studies

Page 1 of 6. Open to participants first (27), then studies with results posted, then the rest; newest registration first within each.

• A Study to Learn About the Effects of Felzartamab on the Kidneys of Adults With Immunoglobulin A Nephropathy (IgAN)Not yet recruitingNCT07889362Phase 2
• A Study to Learn More About Friedrich's Ataxia in People Living in the Gulf Cooperation Council (GCC) Region of the WorldNot yet recruitingNCT07887828
• A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07855211Phase 1/2
• A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years OldRecruitingNCT07722546Phase 2
• A Study to Learn More About the Safety of a Single Dose of BIIB144 and How it is Processed in the Body of Healthy Adult Participants Ages 18 to 55 Years Old as Compared to a PlaceboRecruitingNCT07662148Phase 1
• A Study to Learn About the Safety of Diroximel Fumarate (DRF) and Dimethyl Fumarate (DMF) and Their Effects on Relapses in Pediatric Participants With Relapsing Forms of Multiple Sclerosis (RMS)Not yet recruitingNCT07483632Phase 3
• A Study to Learn More About the Long-Term Safety and Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Antibody-Mediated Rejection (AMR) or Microvascular Inflammation (MVI) (TRANSCEND/TRANSPIRE LTE)Enrolling by invitationNCT07444489Phase 3
• A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With RisdiplamRecruitingNCT07444476Phase 3
• A Study to Learn About the Safety and Effects of Salanersen (BIIB115) When Given to Babies With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene AbeparvovecRecruitingNCT07444450Phase 3
• A Long-Term Study of Patient-Reported Changes in Postpartum Depression Symptoms in People Starting ZuranoloneRecruitingNCT07398469
• A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Participants With Superoxide Dismutase 1 (SOD-1) Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07259980
• A Study to Learn More About the Safety of BIIB145 and How it is Processed in the Body of Healthy Adult ParticipantsRecruitingNCT07225517Phase 1
• A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA)RecruitingNCT07221669Phase 3
• A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular InflammationRecruitingNCT07219043Phase 2
• A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular DegeneratioRecruitingNCT07215390Phase 2
• A Sequential Phase 2/3 Study of APL2 in Patients With Focal Segmental GlomerulosclerosisRecruitingNCT07213960Phase 2/3
• A Study to Learn About the Safety of BIIB142 and How it is Processed in the Body of Healthy Adult Participants Aged 18 to 55 Years OldRecruitingNCT07133828Phase 1
• A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)RecruitingNCT06962800Phase 3
• A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)RecruitingNCT06935357Phase 3
• A Study to Learn How BIIB141 (Omaveloxolone) Affects the Health of Participants With Friedrich's Ataxia Who Took it During Pregnancy and/or During Breastfeeding and About the Health of Their BabiesRecruitingNCT06628687
• A Study to Learn More About the Long-Term Safety of BIIB141 (Omaveloxolone) in Participants With Friedreich's Ataxia Who Are Prescribed it by Their Own DoctorsRecruitingNCT06623890
• A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)RecruitingNCT06555419Phase 1
• A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus ErythematosusEnrolling by invitationNCT06044337Phase 3
• A Study to Learn How Nusinersen (Spinraza) Affects Participants With Spinal Muscular Atrophy (SMA) Who Took it Before or During Pregnancy And About The Health of Their BabiesRecruitingNCT05789758
• Pregnancy Exposure Registry for Vumerity (Diroximel Fumarate)RecruitingNCT05658497
• A Study to Learn More About the Long-Term Safety of Litifilimab (BIIB059) Injections and it's Effects on Symptoms in Adults With Systemic Lupus Erythematosus (SLE)Enrolling by invitationNCT05352919Phase 3
• A Study of Pegcetacoplan in Pediatric Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)RecruitingNCT04901936Phase 2
• A Study to Evaluate the Pharmacokinetics, Safety and Immunogenicity of BIIB800 Subcutaneously (SC) Compared to Actemra® in Healthy Male ParticipantsCompletedNCT06262477Phase 1Results posted
• A Study of RTA 901 (BIIB143) in Participants With Diabetic Peripheral Neuropathic PainTerminatedNCT05895552Phase 2Results posted
• A Study to Assess if BIIB122 Tablets Are Safe and Can Slow Worsening of Early-Stage Parkinson's Disease in Participants With Specific LRRK2 Genetic Variants Between the Ages of 30 and 80 Using the Movement Disorder Society-Unified Parkinson's Disease Rating ScaleTerminatedNCT05418673Phase 3Results posted
• A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's DiseaseTerminatedNCT05310071Phase 3Results posted
• A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple SclerosisTerminatedNCT05265728Phase 3Results posted
• A Study of Diroximel Fumarate (DRF) in Adult Participants From the Asia-Pacific Region With Relapsing Forms of Multiple Sclerosis (RMS)CompletedNCT05083923Phase 3Results posted
• Phase III Study Assessing the Efficacy and Safety of Pegcetacoplan in Patients With C3 Glomerulopathy or Immune-Complex Membranoproliferative GlomerulonephritisCompletedNCT05067127Phase 3Results posted
• Clinical Trial to Assess Efficacy and Safety of the Human Anti-CD38 Antibody Felzartamab (MOR202) in IgA NephropathyCompletedNCT05065970Phase 2Results posted
• A Trial of Bardoxolone Methyl in Patients With CKD at Risk of Rapid Progression (MERLIN)CompletedNCT04702997Phase 2Results posted
• MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04579666Phase 2Results posted
• Study Assessing the Safety and Efficacy of Pegcetacoplan in Post-Transplant Recurrence of C3G or IC-MPGNCompletedNCT04572854Phase 2Results posted
• A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic MutationTerminatedNCT04494256Phase 1/2Results posted
• A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive DisorderCompletedNCT04476030Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of SAGE-217 in Participants With Severe Postpartum Depression (PPD)CompletedNCT04442503Phase 3Results posted
• A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)CompletedNCT04442490Phase 3Results posted
• A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19CompletedNCT04402060Phase 1/2Results posted
• A Study to Evaluate Safety and Tolerability of Aducanumab in Participants With Alzheimer's Disease Who Had Previously Participated in the Aducanumab Studies 221AD103, 221AD301, 221AD302 and 221AD205TerminatedNCT04241068Phase 3Results posted
• Trial to Assess Safety and Efficacy of MOR202 in Anti-PLA2R + Membranous Nephropathy (aMN)CompletedNCT04145440Phase 1/2Results posted
• Study of Nusinersen (BIIB058) in Participants With Spinal Muscular AtrophyCompletedNCT04089566Phase 3Results posted
• A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Patients With PNHCompletedNCT04085601Phase 3Results posted
• A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive DisorderTerminatedNCT04007367Phase 3Results posted
• A Trial of Bardoxolone Methyl in Patients With ADPKD - FALCONTerminatedNCT03918447Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Dimethyl Fumarate (Tecfidera) and Peginterferon Beta-1a (Plegridy) for the Treatment of Relapsing-Remitting Multiple Sclerosis in Pediatric ParticipantsTerminatedNCT03870763Phase 3Results posted
• A Study to Evaluate SAGE-217 in Adult Participants With Major Depressive Disorder (MDD)CompletedNCT03864614Phase 3Results posted
• A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and InsomniaTerminatedNCT03771664Phase 3Results posted
• An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)TerminatedNCT03749447Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS)CompletedNCT03745820Phase 2Results posted
• A Study to Evaluate SAGE-217 in Participants With Bipolar I/II Disorder With a Current Major Depressive EpisodeCompletedNCT03692910Phase 2Results posted
• A Study to Evaluate Efficacy, Safety, and Tolerability of EID of Natalizumab (BG00002) in Participants With RRMS Switching From Treatment With Natalizumab SID in Relation to Continued SID Treatment- Followed by Extension Study Comprising SC and IV Natalizumab AdministrationCompletedNCT03689972Phase 3Results posted
• A Study to Evaluate the Efficacy of SAGE-217 in the Treatment of Adult Participants With Major Depressive DisorderCompletedNCT03672175Phase 3Results posted
• A Study of Aducanumab in Participants With Mild Cognitive Impairment Due to Alzheimer's Disease or With Mild Alzheimer's Disease Dementia to Evaluate the Safety of Continued Dosing in Participants With Asymptomatic Amyloid-Related Imaging AbnormalitiesTerminatedNCT03639987Phase 2Results posted
• A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNHCompletedNCT03593200Phase 2Results posted
• An Efficacy and Safety Study of BG00011 in Participants With Idiopathic Pulmonary FibrosisTerminatedNCT03573505Phase 2Results posted
• A Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525613Phase 3Results posted
• Study to Compare the Efficacy and Safety of Intravitreal APL-2 Therapy With Sham Injections in Patients With Geographic Atrophy (GA) Secondary to Age-Related Macular DegenerationCompletedNCT03525600Phase 3Results posted
• A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111CompletedNCT03507686Phase 2Results posted
• Study to Evaluate the Efficacy and Safety of APL-2 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)CompletedNCT03500549Phase 3Results posted
• Efficacy and Safety of BIIB111 for the Treatment of ChoroideremiaCompletedNCT03496012Phase 3Results posted
• Pegcetacoplan (APL-2) in Neovascular AMDTerminatedNCT03465709Phase 1/2Results posted
• Phase II Study Assessing Safety and Efficacy of APL-2 in GlomerulopathiesCompletedNCT03453619Phase 2Results posted
• A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIXCompletedNCT03366337Phase 2Results posted
• Phase 2 Study of BIIB092 in Participants With Early Alzheimer's DiseaseTerminatedNCT03352557Phase 2Results posted
• Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of BIIB054 in Participants With Parkinson's DiseaseTerminatedNCT03318523Phase 2Results posted
• Phase 2 Efficacy, Safety, and Tolerability Study of Natalizumab in Focal EpilepsyCompletedNCT03283371Phase 2Results posted
• Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With Warm Type Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)CompletedNCT03226678Phase 2Results posted
• Efficacy and Safety of BIIB033 (Opicinumab) as an Add-on Therapy to Disease-Modifying Therapies (DMTs) in Relapsing Multiple Sclerosis (MS)TerminatedNCT03222973Phase 2Results posted
• A Clinical Trial of Retinal Gene Therapy for X-linked Retinitis Pigmentosa Using BIIB112CompletedNCT03116113Phase 1/2Results posted
• A Tolerability Study of ALKS 8700 in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS) EVOLVE-MS-2CompletedNCT03093324Phase 3Results posted
• Long-Term Evaluation of BIIB067 (Tofersen)CompletedNCT03070119Phase 3Results posted
• Study of BIIB092 in Participants With Progressive Supranuclear PalsyTerminatedNCT03068468Phase 2Results posted
• Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGERTerminatedNCT03068130Phase 3Results posted
• A Phase 2/3 Trial of the Efficacy and Safety of Bardoxolone Methyl in Patients With Alport Syndrome - CARDINALCompletedNCT03019185Phase 2/3Results posted
• A Study to Evaluate SAGE-217 in Participants With Parkinson's DiseaseCompletedNCT03000569Phase 2Results posted
• A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive DisorderCompletedNCT03000530Phase 2Results posted
• A Study to Evaluate SAGE-217 in Participants With Essential TremorCompletedNCT02978781Phase 2Results posted
• A Study to Evaluate SAGE-217 in Participants With Severe Postpartum DepressionCompletedNCT02978326Phase 3Results posted
• Efficacy and Safety of Daclizumab in Participants With RRMS Switching From NatalizumabTerminatedNCT02881567Phase 3Results posted
• A Study To Evaluate The Safety And Efficacy Of PF-04958242 In Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS)TerminatedNCT02855411Phase 2Results posted
• Study to Evaluate BIIB059 (Litifilimab) in Cutaneous Lupus Erythematosus (CLE) With or Without Systemic Lupus Erythematosus (SLE)CompletedNCT02847598Phase 2Results posted
• Safety and Efficacy of Intravenous Natalizumab in Acute Ischemic StrokeCompletedNCT02730455Phase 2Results posted
• Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy VolunteersCompletedNCT02691702Phase 1Results posted
• Long-Term Assessment of Remyelinating TherapyCompletedNCT02657915Phase 2Results posted
• Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYSTTerminatedNCT02657356Phase 3Results posted
• A Study of ALKS 8700 in Adults With Relapsing Remitting Multiple Sclerosis (MS) EVOLVE-MS-1CompletedNCT02634307Phase 3Results posted
• An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02623699Phase 3Results posted
• A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational StudiesCompletedNCT02594124Phase 3Results posted
• Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects.CompletedNCT02588833Phase 1Results posted
• Plegridy Satisfaction Study in ParticipantsCompletedNCT02587065Phase 4Results posted
• Extension Study of BG00012 in Pediatric Subjects With Relapsing Remitting Multiple Sclerosis (RRMS)CompletedNCT02555215Phase 3Results posted
• Effect of BG00012 on Lymphocyte Subsets and Immunoglobulins in Subjects With Relapsing Remitting Multiple Sclerosis (RRMS).CompletedNCT02525874Phase 3Results posted
• Study of Pegcetacoplan (APL-2) Therapy in Patients With Geographic AtrophyCompletedNCT02503332Phase 2Results posted
• 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's DiseaseTerminatedNCT02484547Phase 3Results posted
• 221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's DiseaseTerminatedNCT02477800Phase 3Results posted

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