Baylor College of Medicine: Hookworm Infections trials

The registry lists 11 Hookworm Infections studies with Baylor College of Medicine as lead sponsor. 1 are open to participants now and 4 have results posted.

Phase 1 10Phase 2 1(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Experimental Infection of Hookworm-naïve Adults With Dermally-applied Infectious Necator Americanus Hookworm LarvaeRecruitingNCT01940757Phase 1
• Efficacy of Na-GST-1/Alhydrogel Hookworm Vaccine Assessed by Controlled Challenge InfectionCompletedNCT03172975Phase 2Results posted
• Study of Co-administered Na-APR-1 (M74) and Na-GST-1 in Gabonese ChildrenCompletedNCT02839161Phase 1Results posted
• Safety and Immunogenicity Study of Na-GST-1 With or Without CpGCompletedNCT02143518Phase 1Results posted
• Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With Different Doses of a Novel AdjuvantCompletedNCT01385189Phase 1Results posted
• Na-GST-1/Alhydrogel With or Without CpG 10104 in Gabonese AdultsCompletedNCT03373214Phase 1
• Study of Na-APR-1 (M74)/Alhydrogel® Co-administered With Na-GST-1/Alhydrogel in Brazilian AdultsCompletedNCT02476773Phase 1
• Safety and Immunogenicity of Co-Administered Hookworm Vaccine Candidates Na-GST-1 and Na-APR-1 in Gabonese AdultsCompletedNCT02126462Phase 1
• Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy AdultsCompletedNCT01717950Phase 1
• Safety and Immunogenicity of a Human Hookworm Candidate Vaccine With or Without Additional Adjuvant in Brazilian AdultsCompletedNCT01261130Phase 1
• Study of Na-ASP-2 Human Hookworm Vaccine in Healthy Adults Without Evidence of Hookworm InfectionCompletedNCT00120081Phase 1