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CompletedNCT00758251Updated Dec 10, 2010

Observation of Change in Clinical Global Impression Scores in Schizophrenia Patients Receiving Seroquel XR Treatment

An observational study in Schizophrenia, sponsored by AstraZeneca. Completed at 15 sites in Latvia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2010-12-10.

Sponsored by AstraZeneca · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
80
Ages
18 Years and older
Sex
All
01

Study summary

The purpose of this study is to assess severity of illness in schizophrenia patients in routine clinical practice at the time of entry in the study and after the treatment with Seroquel XR for 8 weeks.

PLEASE NOTE: Seroquel SR and Seroquel XR refer to the same formulation. The SR designation was changed to XR after consultation with FDA.

02

Conditions studied

  • Schizophrenia

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Keywords

  • Schizophrenia
  • Seroquel XR
  • CGI
03

In context

Schizophrenia

3,471 studies on the registry are indexed under Schizophrenia; 472 are open to participants now.

This study's planned enrollment of 80 is below the median of 178 across 491 observational studies indexed under Schizophrenia.

Browse Schizophrenia studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

primary care clinics

Inclusion criteria

  • Adult patients with Schizophrenia prescribed on Seroquel XR according to the approved product information before inclusion in this non-interventional study
  • Signed and dated Patient Informed Consent (ICF)

Exclusion criteria

Exclusion Criteria:

  • Hypersensitivity to the active substance or to any of the excipients of Seroquel XR
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
80 participants (estimated)

Groups and cohorts

  • 1

    Adult schizophrenia patients already on Seroquel XR therapy

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What researchers measure

Primary outcomes

  1. Improvement in CGI scores and BPRS comparing visits 1 and 3.

    Time frame: twice with 4 week interval

Secondary outcomes

  1. To evaluate compliance to therapy

    Time frame: twice with 4 week interval

07

Study locations

15 sites
  • Research Site
    Bauska, Latvia
  • Research SIte
    Cesis, Latvia
  • Research Site
    Daugavpils, Latvia
  • Research Site
    Dobele, Latvia
  • Research Site
    Jekabpils, Latvia
  • Research Site
    Jelgava, Latvia
  • Research Site
    Jurmala, Latvia
  • Research Site
    Kuldiga, Latvia
  • Research Site
    Liepaja, Latvia
  • Research Site
    Riga, Latvia
  • Research Site
    Saldus, Latvia
  • Research Site
    Strenci, Latvia
  • Research Site
    Talsi, Latvia
  • Research Site
    Tukums, Latvia
  • Research Site
    Valmiera, Latvia
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 10, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00758251
Lead sponsor
AstraZeneca
First posted
Sep 25, 2008
Start date
Sep 2008
Primary completion
Mar 2009
Completion
Mar 2009
Last update
Dec 10, 2010

Study contacts

Agrita Hartmane
study director · AstraZeneca Latvia

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2010. You cannot join it, but the record below documents what was studied.

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