CClinicalTrials.gg
CompletedNCT01214135SPINUpdated Jan 11, 2011

A Retrospective Non-interventional Study to Evaluate the Use of Seroquel Extended Release (XR) and Immediate Release (IR) in the Clinical Practice of Inpatients With Schizophrenia

An observational study in Schizophrenia, sponsored by AstraZeneca. Completed at 14 sites in Sweden. Open to participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2011-01-11.

Sponsored by AstraZeneca · Observational

Study type
Observational
Model
Case-control
Time perspective
Retrospective
Enrollment
300
Ages
18 Years to 65 Years
Sex
All
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Study summary

The primary objective of this non-interventional study is to investigate how Seroquel XR and Seroquel IR are used in the clinical practice of inpatients with schizophrenia. This will be done by a retrospective review of medical records to evaluate patients treated with Seroquel XR or Seroquel IR as primary antipsychotic treatment.

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Conditions studied

  • Schizophrenia

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Keywords

  • Mental disorder
  • antipsychotic treatment
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In context

Schizophrenia

3,471 studies on the registry are indexed under Schizophrenia; 472 are open to participants now.

This study's planned enrollment of 300 is above the median of 178 across 491 observational studies indexed under Schizophrenia.

Browse Schizophrenia studies →

Lead sponsor

AstraZeneca is the lead sponsor of 3,429 studies on the registry; 270 are open to participants now.

Of its 357 completed or terminated interventional studies of FDA-regulated products, 173 (48%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Approximately 300 patients with schizophrenia who have been hospitalized during the study period (1st of July 2009 - 30th of September 2010).

Inclusion criteria

  • Diagnosis of schizophrenia.
  • At least one dose of Seroquel XR or Seroquel IR during the study period (1st of July 2009 - 30th of September 2010).
  • Hospitalization due to psychotic symptoms at any time during the study period (1st of July 2009 - 30th of September 2010) and with admission and discharge dates available.

Exclusion criteria

Exclusion Criteria:

  • Participation in a clinical trial during the study period.
  • Treatment in forensic care according to LRV ("Lagen om Rättspsykiatrisk Vård").
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Study design

Observational model
Case-control
Time perspective
Retrospective
Enrollment
300 participants (estimated)

Groups and cohorts

  • 1

    Patients with a diagnosis of schizophrenia who have been hospitalized and received at least one dose of Seroquel XR or Seroquel IR during the study period (1st of July 2009 - 30th of September 2010).

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What researchers measure

Primary outcomes

  1. To investigate how Seroquel XR and Seroquel IR are used in the clinical practice of inpatients with schizophrenia

    Time frame: every day for the time period of 15 Oct to 31 Dec 2010

Secondary outcomes

  1. To investigate comorbidities of patients with schizophrenia receiving Seroquel XR and IR

    Time frame: every day for the time period of 15 Oct to 31 Dec 2010

  2. To investigate whether Seroquel XR and Seroquel IR are used to treat different types of inpatients with schizophrenia by evaluation of patient characteristics

    Time frame: every day for the time period of 15 Oct to 31 Dec 2010

  3. To investigate the treatment sequence of Seroquel XR and Seroquel IR in the clinical practice of patients with schizophrenia by evaluation of duration, dosage, reason for treatment, and, if applicable, reason for change, with Seroquel XR and Seroquel IR

    Time frame: every day for the time period of 15 Oct to 31 Dec 2010

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Study locations

14 sites
  • Research Site
    Falköping, Sweden
  • Research Site
    Gothenburg, Sweden
  • Research Site
    Helsingborg, Sweden
  • Research Site
    Karlskrona, Sweden
  • Research Site
    Karlstad, Sweden
  • Research Site
    Lund, Sweden
  • Research Site
    Malmö, Sweden
  • Research Site
    Mölndal, Sweden
  • Research Site
    Stockholm, Sweden
  • Research Site
    Trollhättan, Sweden
  • Research Site
    Umeå, Sweden
  • Research Site
    Uppsala, Sweden
  • Research Site
    Växjö, Sweden
  • Research Site
    Öjebyn, Sweden
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References and documents

Publications

  • Eriksson L, Hallerback T, Jorgensen L, Carlborg A. Use of quetiapine XR and quetiapine IR in clinical practice for hospitalized patients with schizophrenia: a retrospective study. Ther Adv Psychopharmacol. 2012 Dec;2(6):217-26. doi: 10.1177/2045125312453935. PubMed 23983980 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 11, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01214135
Lead sponsor
AstraZeneca
First posted
Oct 4, 2010
Start date
Oct 2010
Primary completion
Dec 2010
Completion
Dec 2010
Last update
Jan 11, 2011

Study contacts

Dr Eva Dencker Vansvik, MD
study director · AstraZeneca
Dr Lars Eriksson, MD
principal investigator · Rättspsykiatriska Vårdkedjan, Hisings-Backa, Sweden

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2011. You cannot join it, but the record below documents what was studied.

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