AstraZeneca: Asthma trials

The registry lists 359 Asthma studies with AstraZeneca as lead sponsor. 19 are open to participants now and 129 have results posted.

Phase 1 46Phase 2 52Phase 3 123Phase 4 23No phase 117(a study in two phases counts in both)

Studies

Page 3 of 4. Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Evaluation of AZD8154 Concentrations in BloodTerminatedNCT04480879Phase 1
• ChAracterisation of ItaliaN Severe Uncontrolled Asthmatic patieNts Key Features When Receiving BenralizumabCompletedNCT04272463
• Patient-reported Outcomes in Real-world Use of Benralizumab in Patients With Severe Eosinophilic Asthma in BelgiumCompletedNCT04221802
• Real-life First Dose Effect of Fasenra in Patients With Severe Uncontrolled AsthmaCompletedNCT04200326
• A Study to Evaluate the Effect of AZD8154 Administered Via Nebulizer Once Daily in Subjects With Mild Allergic Asthma Challenged With an Inhaled AllergenWithdrawnNCT04187508Phase 2
• Change in Patient-Reported Outcomes in Severe Eosinophilic Asthma Patients Treated With Benralizumab Under Real-life ConditionsCompletedNCT04184284
• A Study to Evaluate the Amount of Drug That Becomes Available to the Blood Circulation When Inhaled by a Nebulizer and Dry Powder Inhaler in Healthy Subjects.CompletedNCT04072562Phase 1
• Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594CompletedNCT04002427Phase 1
• A Study to Evaluate the Pharmacokinetics of Tezepelumab After Being Delivered by an Accessorized Pre Filled Syringe or Autoinjector Compared With Vial and Syringe in Healthy Adult SubjectsCompletedNCT03989544Phase 1
• A Study to Assess the Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of 2-Week Treatment With Inhaled AZD7594 in Adolescents (12 to 17 Years) With AsthmaCompletedNCT03976869Phase 1
• Retrospective Analysis to Describe Patient Profiles, Current Treatment Patterns and Economic Burden for Asthma Patients in UAE. A Descriptive Analysis of the Asthma Patient Population in the Emirate of Dubai With Respect to Healthcare Resource Utilization, Costs, and Asthma-related Treatment PatternCompletedNCT03963141
• Benralizumab Airway Remodeling Study in Severe Eosinophilic AsthmaticsCompletedNCT03953300Phase 4
• Prevalence of the Eosinophilic Phenotype Among Severe Asthma PatientsCompletedNCT03931954
• BRazilian Asthmatics Patients EOSinophilic Profile (BRAEOS)CompletedNCT03925415
• Study to Assess Effect of Device and Formulation on Pharmacokinetics (PK) of AZD1402CompletedNCT03921268Phase 1
• Prevalence of Asthma and Allergies Among Children in UAECompletedNCT03878680
• SABINA INTERNATIONALCompletedNCT03857178
• Assessment of Asthma Control Level in Primary Care Setting in MalaysiaCompletedNCT03804632
• Benralizumab Pregnancy Exposure StudyTerminatedNCT03794999
• Characterisation of Patients With Severe Asthma in Primary and Secondary Care Settings in Europe Reported to be Eligible for Biological TherapyCompletedNCT03629782
• FASENRA SCEI for Long-term UseCompletedNCT03588546
• A Study to Evaluate the Safety, Tolerability and Absorption to the Blood After Administration of Single and Multiple Doses of AZD8154 in Healthy Participants.CompletedNCT03436316Phase 1
• Assessment of Treatment Patterns of Severe Asthmatic Patients Across the Gulf Region - SevEos StudyCompletedNCT03387722
• Observational Study of Characteristics, Treatment and Outcomes With Severe Asthma in the United States (CHRONICLE)CompletedNCT03373045
• Assessment of Asthma Control Level in MalaysiaCompletedNCT03295331
• To Assess the Pharmacokinetics, Safety and Tolerability of Abediterol Administered Once Daily for 9 Days, in Patients With Asthma on Inhaled CorticosteroidsCompletedNCT03273127Phase 1
• Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of AZD8871 in Healthy Male Japanese SubjectsCompletedNCT03159442Phase 1
• A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of AZD9898TerminatedNCT03140072Phase 1
• A Study to Evaluate the Disposition of Drug in Body and Safety After Administration of Single Inhaled Doses of Drugs Abediterol and AZD7594 Administered Alone, in Fixed Dose Combination and in Free Combination Using the Dry Powder Inhaler in Healthy Male ParticipantsCompletedNCT02967159Phase 1
• A Study to Assess How Much Drug Reaches the Blood When Given From Symbicort pMDI With Spacer Compared to That of Symbicort pMDI Without Spacer in Healthy VolunteersCompletedNCT02934607Phase 1
• A Study to Assess the Effect of Particle Size of AZD7594 on Pharmacokinetics (PK) After a Single Inhaled Dose When Administered Using the Dry Powder Inhaler in Healthy VolunteersCompletedNCT02928354Phase 1
• Non-interventional Study of COPD Patients With Asthma Overlap Syndrome in Viet Nam and TaiwanCompletedNCT02878252
• Observational Study of Obstructive Lung Disease (NOVELTY)CompletedNCT02760329
• Asthma Control, Quality of Life and Emotional Feelings in a Real Life SettingCompletedNCT02640742
• Multicentric, Transversal, Descriptive, Epidemiological Study on the Management of Asthma in Asthmatic Middle East Adult PopulationCompletedNCT02153411
• The Severity of Newly Diagnosed Asthma Patients and the Result of Initial 12 Weeks Treatment in ChinaCompletedNCT02143739
• Study to Investigate Relative Bioavailability of up to Five Different Formulations of AZD5069CompletedNCT01989520Phase 1
• Acid-suppressing Drugs Pregnancy Asthma Offspring StudyCompletedNCT01787435
• The Asthma Control Rate Achieved by Budesonide/Formoterol in Clinical Practice in ChinaCompletedNCT01785901
• Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.CompletedNCT01735240Phase 1
• Clinical Experience Investigation of Symbicort Turbuhaler as Maintenance Therapy and Reliever TherapyCompletedNCT01711840
• Asthma Comparative Effectiveness StudyCompletedNCT01623544
• Observational Study to Evaluate the Correctness of the Use of Inhaler Device in Patients With Asthma or Chronic ObstructCompletedNCT01426893
• The Predictors for Asthma Control by Stepwise Treatment During 6 Months in Korean ElderlyCompletedNCT01370577
• Outcome Study Following Reimbursement Changes in the Use of Fixed Combination Inhalers in Patients With Asthma or Chronic Obstructive Pulmonary DiseaseCompletedNCT01369810
• A Study to Evaluate the Effect of Roflumilast on Airway Inflammation and Function Following Allergen Challenge in Subjects With Allergic AsthmaCompletedNCT01365533Phase 2
• A Study to Assess Selected Biomarkers in Subjects Requiring Daily Inhaled Corticosteroids for Persistent AsthmaCompletedNCT01334853
• Utilization of Fixed Combination (Budesonide/Formoterol and Salmeterol/Fluticasone and Beclomethasone/Formoterol) in Treatment of Asthma PatientsCompletedNCT01327001
• A Study in Healthy Subjects and Mild Asthmatics to Investigate Pharmacokinetics of AZD5423 When Administered in Different WaysCompletedNCT01310322Phase 1
• Asthma Control Study 2011CompletedNCT01298739
• Asthma in ChildrenCompletedNCT01286532
• Non-interventional Retrospective Multicenter Study of Patients With Bronchial Asthma During a Routine Visit to Out of Patients' ClinicsCompletedNCT01273363
• To Investigate the Effects of AZD1981 on the QT IntervalCompletedNCT01265641Phase 1
• Symbicort Turbuhaler 30/60 Clinical Experience InvestigationCompletedNCT01232348
• Symbicort Turbuhaler 30/60 Specific Clinical Experience InvestigationCompletedNCT01232335
• Pulmicort Respules 0.25/0.5 Specific Clinical Experience InvestigationCompletedNCT01232322
• Pulmicort Turbuhaler 100/200 Specific Clinical Experience InvestigationCompletedNCT01203904
• Pharmacokinetics in AdolescentsCompletedNCT01196689Phase 1
• ATEM (Alvesco Non-interventional Study)CompletedNCT01147224
• Estimating the Use of Resources and the Costs of Treating Patients With Asthma in the Autonomous Community of ValenciaCompletedNCT01114906
• Effect of a Pharmaceutical Intervention on the Level of Control of the Asthmatic PatientCompletedNCT01085474
• Economic Evaluation of Heart Failure Management in Colombian ClinicsCompletedNCT01084564
• Evaluation of the Frequency of Limitation of Activity in Patients With Persistent AsthmaCompletedNCT01078688
• A Study for the Assessment of the Words Used by Patients and Physicians to Express Asthma SymptomsCompletedNCT00986219
• Symbicort SMART Satisfaction From Patient Perspective 2009CompletedNCT00946452
• Cost-effectiveness Study of Symbicort as Maintenance and Reliever Therapy (SMART)CompletedNCT00937066
• Asthma Control and Clinical Practice in Hungary 2009CompletedNCT00900861
• A 6 Months NIS to Evaluate the Use of Rescue Medication and Quality of Life in Adult Asthmatic Subjects Treated With Symbicort® SMART®CompletedNCT00884689
• Evaluation of the Control Level of Asthmatic Patients With Seasonal Increase of Respiratory Symptoms (High and/or Low)CompletedNCT00882128
• Ciclesonide for the Treatment of Airway HyperresponsivenessCompletedNCT00826969Phase 4
• Symbicort Usage in Asthma Treatment and Impact of a New Therapeutic Strategy on Compliance and Asthma Control in FranceCompletedNCT00812357
• Asthma Control Among Patients Receiving Inhaled Corticosteroids in ThailandCompletedNCT00800904
• Budesonide/Formoterol for Maintenance and Reliever Therapy Among Asthma Patients in ThailandCompletedNCT00800241
• NIS-observe Treatment Efficacy in Maintaining Symptoms Control in Moderate/Severe Asthma With Symbicort SMARTCompletedNCT00785733
• Real Life Effectiveness in Patients With Not Optimally Controlled AsthmaCompletedNCT00784953
• Evaluating the Symbicort Turbuhaler (Formoterol/Budesonide) Maintenance and Reliever Therapy for Asthma in Daily PracticeCompletedNCT00782314
• National Survey on AsthmaCompletedNCT00770250
• CARE - Quality Improvement in Asthma Secondary Prevention in Primary Care, Through Delegation of Consultations to the Nurse.CompletedNCT00714038
• Does Tailored Education in Asthma Care Help Improve Patient Satisfaction, Adherence, and Quality of Life (TEACH) TrialCompletedNCT00687310Phase 4
• Asthma Patient Survey Study to Assess Asthma Effect and Medication in FinlandCompletedNCT00681382
• Utilization Patterns of Pulmicort in Real Life PracticeCompletedNCT00660569
• A Study to Evaluate the Safety, Tolerability and Effects of MEDI-563 in Adults With AsthmaCompletedNCT00659659Phase 1
• Relative Bronchodilating Effects of Formoterol When Administered Via Symbicort Pressurized Metered-dose Inhaler (pMDI) or Oxis TurbuhalerCompletedNCT00658255Phase 2
• Efficacy of Symbicort pMDI Administered Once Daily in Adolescents and Adults During 12 Weeks - STEMCompletedNCT00652392Phase 3
• Efficacy of Symbicort Versus Its Monocomponents - SPRUCE 160/4.5CompletedNCT00652002Phase 3
• Titratable Dosing in Moderate to Severe AsthmaticsCompletedNCT00651768Phase 3
• Efficacy of Symbicort Versus Its Monocomponents - SPRUCE 80/4.5CompletedNCT00651651Phase 3
• Symbicort in Asthmatic Children - SEEDLINGCompletedNCT00651547Phase 3
• Symbicort Onset of Action 1CompletedNCT00646620Phase 3
• Atlantis SymbicortCompletedNCT00646594Phase 3
• Long-Term Safety of Symbicort in Asthmatic Children - SAPLINGCompletedNCT00646529Phase 3
• Gemini Symbicort pMDICompletedNCT00646516Phase 3
• Efficacy of Symbicort pMDI Administered Once Daily in Children and Adolescents During 12 Weeks - SPROUTCompletedNCT00646321Phase 3
• Symbicort Onset of Action 2CompletedNCT00646009Phase 3
• New Version Pulmicort Turbuhaler USA AdultsCompletedNCT00642187Phase 3
• New Version Pulmicort Turbuhaler USA ChildrenCompletedNCT00642161Phase 3
• Adults With Moderate to Severe AsthmaCompletedNCT00642122Phase 3
• Inhaled Steroid Treatment as Regular Therapy in Early AsthmaCompletedNCT00641914Phase 4
• Pulmicort Respules(Budesonide Inhalation Suspension) vs Singulair, ChildrenCompletedNCT00641472Phase 4
• Varicella Vaccination With PulmicortCompletedNCT00641446Phase 4