BiologicalDrug
VRC07-523LS clinical trials
Also written VRC07-523LS.
- studies test it
- 22
- open now
- 4
- in phase 3
- 0
- first study started
- 2015
Keep track of what changes. Save the VRC07-523LS studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Combined with it in one product
Studies by the year they started
22 studies that test it; most in 2018 (3)
| Year | Studies |
|---|---|
| 2015 | 2 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 3 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 2 |
| 2026 | 3 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 18
- Phase 2
- 8
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 20
National Institute of Allergy and Infectious Diseases (NIAID) (15) · TaiMed Biologics Inc. (1) · David Ho (1) · Boris Juelg, MD PhD (1) · Gilead Sciences (1) · International AIDS Vaccine Initiative (1) · University of North Carolina, Chapel Hill (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1)
Often tested with
Tested in the same studies.
PGDM1400LS (5) · PGT121.414.LS (3) · Ad26.Mos4.HIV (2) · PGT-121 (2) · VRC-01LS (2) · VRC-01 (2) · TMB-365 (1) · Ibalizumab (1)
Studies
Open first, then newest update. How each study uses VRC07-523LS is read from its arms, and is right about nine times in ten.
Testing it · 22
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 InfectionNot yet recruitingPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT06987318Written as VRC07-523LS
- Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV RemissionRecruitingPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT02140255Written as VRC07-523LS
- A Study of Safety and Drug Levels of ePGT121v1-LS, PGDM1400LS, and VRC07-523LS in Adult Participants Without HIV-1RecruitingPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT07390955Written as VRC07-523LS (IV)
- Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1RecruitingPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT06517693Written as VRC07-523LS
- The Tatelo Plus StudyActive, not recruitingPhase 1/2National Institute of Allergy and Infectious Diseases (NIAID)NCT06508749Written as VRC07-523LS
- A Study of VRC07-523LS, PGT121.414.LS, and PGDM1400LS Broadly Neutralizing Monoclonal Antibodies Given Intravenously in Adult Participants Without HIVActive, not recruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT06812494Written as VRC07-523LS 400mg
- HIV-1 Virologic Suppression With TMB-365 and TMB-380 Antibodies StudyActive, not recruitingPhase 2TaiMed Biologics Inc.NCT07215468Written as TMB-380
- 10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected AdultsActive, not recruitingPhase 1David HoNCT05890963Written as VRC07-523LS
- Safety, Immunogenicity, Efficacy of Ad26.Mos4.HIV, MVA-BN-HIV and PGT121, PGDM1400, and VRC07-523LS in HIV-1-Infected AdultsCompletedPhase 1/2Boris Juelg, MD PhDNCT04983030Written as VRC07-523LS
- Study of VRC07-523LS, CAP256V2LS, and Vesatolimod, in Early Antiretroviral-treated HIV-1 Clade C-infected WomenCompletedPhase 2Gilead SciencesNCT05281510Written as VRC07523LS
- Evaluating the Safety and Pharmacokinetics of VRC07-523LS in the Sera and Mucosae of Healthy, HIV-Uninfected Adult ParticipantsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03735849Written as VRC07-523LS
- Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1CompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT03739996Written as VRC07-523LS
- A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult ParticipantsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT05184452Written as VRC07-523LS (20mg/kg, IV)
- Phase 1, Open-label, Single Dose Study to Examine Safety, Tolerability, Pharmacokinetics and Virologic Impact of VRC01LS or VRC07-523LS in HIV-infected Viremic AdultsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT02840474Written as VRC-HIVMAB075-00-AB
- Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of the Monoclonal Antibody PGT121.414.LS Administered Alone and in Combination With VRC07-523LS Via Intravenous or Subcutaneous Infusions in Healthy, HIV-uninfected Adult ParticipantsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT04212091Written as VRC07-523LS
- Safety and Efficacy of Neutralizing Antibodies and Vaccination for Induction of HIV RemissionWithdrawnPhase 1Henry M. Jackson Foundation for the Advancement of Military MedicineNCT05769569Written as VRC07-523LS
- Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected AdultsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03387150Written as VRC07-523LS
- Evaluating the Safety and Pharmacokinetics of VRC01, VRC01LS, and VRC07-523LS, Potent Anti-HIV Neutralizing Monoclonal Antibodies, in HIV-1-Exposed InfantsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT02256631Written as VRC07-523LS
- A Phase 1/2a Study of PGT121, VRC07-523LS and PGDM1400 Monoclonal Antibodies in HIV-uninfected and HIV-infected AdultsCompletedPhase 1/2International AIDS Vaccine InitiativeNCT03721510Written as PGT121 + VRC07-523LS
- Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected PersonsCompletedPhase 1University of North Carolina, Chapel HillNCT03803605Written as VRC07-523LS
See all 22 studies that test VRC07-523LS →
Given in every arm · 4 — VRC07-523LS is usual care beside what is tested
- A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV RemissionRecruitingPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT05719441Written as VRC07-523LS
- RV630 - Approach to Control HIV With Immune Enhancement and Vaccination (ACHIEVRecruitingPhase 1Henry M. Jackson Foundation for the Advancement of Military MedicineNCT06484335Written as VRC07-523LS
- Safety, Tolerability, and Efficacy of IL-15 Superagonist (N-803) With and Without Combination Broadly Neutralizing Antibodies to Induce HIV-1 Control During Analytic Treatment InterruptionActive, not recruitingPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT04340596Written as VRC07-523LS
- Evaluating the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Combinations of Monoclonal Antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS Administered Via Intravenous Infusion in Healthy, HIV-uninfected Adult ParticipantsCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT03928821Written as VRC07-523LS