Varenicline: all 249 studies that test it

Page 2 of 3. Open to participants first (19), then studies with results posted, then the rest; newest registration first within each.

• Safety And Efficacy Of 12 Weeks Of Varenicline For Smoking Cessation In Smokers With DepressionCompletedNCT01078298Phase 4Results posted
• Smoking Cessation Treatment for Methadone Maintenance PatientsCompletedNCT01027754Phase 4Results posted
• Distribution of Bupropion and Varenicline to Increase Smoking Cessation AttemptsCompletedNCT01023659Phase 4Results posted
• A Pilot Clinical Trial of Varenicline as a Treatment for Alcohol DependenceCompletedNCT01011907Not applicableResults posted
• Varenicline vs Placebo for the Treatment of Methamphetamine DependenceCompletedNCT01011829Phase 2Results posted
• Varenicline Treatment for Smoking Cessation in Patients With Bipolar DisorderCompletedNCT01010204Phase 4Results posted
• Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use DisordersCompletedNCT01000987Phase 2Results posted
• Measuring Smoking Behaviors While Using VareniclineCompletedNCT00948155Phase 4Results posted
• Relapse Prevention With VareniclineCompletedNCT00944554Phase 4Results posted
• Impact of Varenicline on Blood-Oxygen-Level Dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Activation on SmokersCompletedNCT00934024Not applicableResults posted
• Chantix in Adult Smokers With Attention Deficit Hyperactivity Disorder (ADHD)TerminatedNCT00907218Phase 4Results posted
• Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and GenotypeCompletedNCT00894166Phase 3Results posted
• A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned SurgeryCompletedNCT00889720Phase 4Results posted
• Varenicline for Smoking Cessation in Heavy Drinking SmokersCompletedNCT00860028Phase 2Results posted
• An Alternative Dosing Schedule of Varenicline for Smoking CessationCompletedNCT00835900Phase 2Results posted
• Long-term Varenicline Treatment for Smoking CessationCompletedNCT00828113Phase 4Results posted
• Varenicline for the Treatment of Smokeless TobaccoCompletedNCT00813917Not applicableResults posted
• Varenicline in Bipolar Depressed PatientsCompletedNCT00813800Not applicableResults posted
• Varenicline for Cognitive Deficits and Cigarette Smoking in Schizophrenia - Efficacy and PredictorsCompletedNCT00802919Phase 4Results posted
• Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) TrialCompletedNCT00794573Phase 3Results posted
• Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop SmokingCompletedNCT00790569Not applicableResults posted
• Use of Varenicline for 4-weeks Prior to QuittingCompletedNCT00789074Phase 3Results posted
• The Effect of Naltrexone and Varenicline on Alcohol-Mediated Smoking LapseCompletedNCT00773422Phase 2Results posted
• Varenicline and Motivational Advice for Smokers With Substance Use DisordersCompletedNCT00756275Not applicableResults posted
• Assessing Neuropsychiatric Symptoms Including Depression, Anxiety, Irritability, and Suicidal Thoughts or Behavior in Subjects Quitting Smoking on Varenicline Tartrate or PlaceboCompletedNCT00749944Phase 4Results posted
• Human Laboratory Study of Varenicline and Bupropion for Nicotine DependenceCompletedNCT00749658Phase 2/3Results posted
• Varenicline Effects on Cue Reactivity and Smoking Reward/ReinforcementCompletedNCT00747643Not applicableResults posted
• Evaluation of the Efficacy of Varenicline on Cognition, Safety, Tolerability and Pharmacokinetics in Subjects With Mild-to-Moderate Alzheimer's DiseaseCompletedNCT00744978Phase 2Results posted
• Effects of Varenicline on Cigarette Self AdministrationCompletedNCT00731055Phase 2Results posted
• Study Evaluating The Efficacy Of Varenicline In Cessation Of Oral Smokeless Tobacco UseCompletedNCT00717093Phase 4Results posted
• Human Laboratory Study Of Varenicline in SmokersCompletedNCT00709696Not applicableResults posted
• Varenicline (Chantix™) for the Treatment of Alcohol DependenceCompletedNCT00705523Phase 2Results posted
• Varenicline to Reduce Alcohol Consumption in Heavy DrinkersCompletedNCT00695500Phase 1/2Results posted
• Randomized Study Comparing the Efficacy and Safety of Varenicline Tartrate to Placebo in Smoking Cessation When Subjects Are Allowed to Set Their Own Quit DateCompletedNCT00691483Phase 4Results posted
• Endothelial Function and Autonomic Regulation After Short-term Smoking Cessation: Varenicline Versus PlaceboTerminatedNCT00673595Not applicableResults posted
• Menstrual Cycle Effects on Smoking Cessation and Cue ReactivityCompletedNCT00664755Phase 2Results posted
• Smoking Cessation Study for Patients With Schizophrenia or Schizoaffective DisorderCompletedNCT00644969Phase 3Results posted
• A Study of Varenicline for Prevention of Relapse to Smoking in Patients With Schizophrenia or Bipolar DisorderCompletedNCT00621777Phase 4Results posted
• Varenicline and Nicotine Interactions in Humans (VA)CompletedNCT00606892Not applicableResults posted
• Effects of Varenicline on Brain Activity During Nicotine AbstinenceCompletedNCT00602927Not applicableResults posted
• Efficacy of Varenicline in Ambivalent SmokersCompletedNCT00595868Phase 2Results posted
• Assessment of Safety and Efficacy of Varenicline in Patients That Wish to Stop SmokingCompletedNCT00594204Phase 4Results posted
• Chantix & Bupropion for Smoking CessationCompletedNCT00587769Phase 3Results posted
• The Effect of Varenicline (Chantix) and Bupropion (Zyban) on Smoking Lapse BehaviorCompletedNCT00580853Phase 2Results posted
• Do Treatments for Smoking Cessation Affect Alcohol Drinking?CompletedNCT00580645Phase 2Results posted
• Smoking Cessation Intervention for Thoracic PatientsCompletedNCT00580398Phase 1/2Results posted
• Efficacy of Varenicline in Methadone-Stabilized Cocaine UsersCompletedNCT00567320Not applicableResults posted
• Chantix for Treating Cocaine DependenceCompletedNCT00567008Phase 2Results posted
• Comparison of Varenicline and Placebo for Smoking Cessation in SchizophreniaCompletedNCT00554840Phase 2Results posted
• Varenicline Effects In Schizophrenic SmokersCompletedNCT00548470Phase 4Results posted
• Study of Mood Effects of Varenicline (Chantix) in Depressed Outpatient SmokersCompletedNCT00525837Not applicableResults posted
• Pharmacogenetics, Emotional Reactivity and SmokingCompletedNCT00507728Phase 2/3Results posted
• Varenicline Adjunctive Treatment in SchizophreniaCompletedNCT00492349Phase 4Results posted
• Study of the Effects of Mecamylamine and Varenicline in SchizophreniaCompletedNCT00455650Not applicableResults posted
• Efficacy and Safety of Varenicline in Smokers With Cardiovascular Disease Who Wish to Quit SmokingCompletedNCT00282984Phase 3Results posted
• A Study of Varenicline in the Treatment of Visceral SensationCompletedNCT06854406Phase 1
• Efficacy of Varenicline Tartrate in Treating Frequent Premature Ventricular ContractionsCompletedNCT06780215Phase 2
• Concurrent vs. Sequential Cessation of Dual Cigarette and E-cigarette UseCompletedNCT06027840Phase 1
• Off-Label Medications for Alcohol Use Disorder Among Patients With HIV: Pilot Study 2Active, not recruitingNCT06006143Phase 2
• Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye DiseaseCompletedNCT05576415Phase 1
• Evaluation of Tear Film Quality and Stability in Subjects With Dry Eye Disease Using OC-01 (Varenicline Solution) Nasal Spray 0.03 mg as Compared to Vehicle Control Nasal SprayCompletedNCT05514041Phase 4
• Clinical Trial to Evaluate the Efficacy and Safety of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT05378945Phase 3
• Varenicline for the Treatment of Cannabis and Tobacco Use Disorders in VeteransWithdrawnNCT05294263Phase 2
• Effectiveness of an Enhanced Tobacco Intervention Protocol Compared to Standard Treatment in Helping Head and Neck and Lung Cancer Patients Starting Treatment to Reduce Cigarette UseCompletedNCT04694846Not applicable
• Tobacco Treatment Optimization and Preferences During Concurrent Cancer TreatmentCompletedNCT04634071Phase 2
• Feasibility of Treatment for Vaping CessationWithdrawnNCT04317300Early Phase 1
• A Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HIP1502CompletedNCT04018378Phase 1
• Varenicline Versus Cytisine for Smoking Cessation in Primary Care SettingCompletedNCT04015414Phase 3
• Varenicline for Smoking Cessation in Hospitalized Patients With Psychiatric DisordersWithdrawnNCT03809897Phase 4
• A Trial of Directly Observed and Long-term VareniclineCompletedNCT03365362Phase 4
• Compare the Pharmacokinetic Characteristics and the Safety Between Zeropix and Champix in Healthy Adult Male Subjects.CompletedNCT03362008Phase 1
• Dopamine D2/D3 Receptor Upregulation by Varenicline in Methamphetamine UsersTerminatedNCT03059563Phase 1
• Treating Smokeless Tobacco Use in Rural VeteransStatus unknownNCT02994082Not applicable
• Combined Bio- and Neuro- Feedback vs. Varenicline Use for Smoking CessationCompletedNCT02991781Not applicable
• Smoking Cessation Intervention in Respiratory InpatientsCompletedNCT02922387Phase 4
• Varenicline for "Gradual" vs. "Abrupt" Smoking Cessation in Low-motivated COPD SmokersStatus unknownNCT02894957Phase 4
• Smoking Relapse Prevention Among COPD Ex-smokersTerminatedNCT02888444Phase 3
• Studying Partial-agonists for Ethanol and Tobacco Elimination in Russians With HIV (St PETER HIV)CompletedNCT02797587Phase 2/3
• Effect of Smoking Cessation on Clinical and Microbiological Outcomes of the Non-surgical Periodontal TherapyCompletedNCT02744417Not applicable
• Extended (6-Week) Varenicline Preloading: Does it Facilitate Smoking Reduction and Cessation?CompletedNCT02634281Phase 4
• Varenicline (Chantix) Treatment for Waterpipe Smoking CessationCompletedNCT02575183Phase 4
• Effects of Varenicline in Heavy Drinking SmokersWithdrawnNCT02488889Phase 4
• Varenicline Treatment for Excessive Daytime Sleepiness in Parkinson's DiseaseTerminatedNCT02473562Phase 4
• Effect of Smoking Reduction on Endothelial Glucocalyx and Vascular FunctionStatus unknownNCT02307045Phase 4
• Smoking Young Asthmatics: Change of Inflammation During Tobacco Cessation and Steroid TreatmentCompletedNCT02233231Phase 4
• Reward Sensitivity and Pharmacotherapy for Smoking CessationActive, not recruitingNCT02162849Phase 4
• The MATCH (Medication Aids for Tobacco Cessation and Health) StudyCompletedNCT02146911Not applicable
• Early In-hospital Initiation of Pharmacotherapy for Smoking Cessation, Patients After ACSStatus unknownNCT02106637Not applicable
• Effects of Varenicline on Plasticity in SchizophreniaCompletedNCT01934023Phase 2
• Effects of Varenicline on Smoking Lapse in Smokers With and Without SchizophreniaCompletedNCT01850953Phase 4
• The Canadian HIV Quit Smoking Trial: Tackling the Co-morbidities of Depression and Cardiovascular Disease in HIV+ SmokersStatus unknownNCT01800019Phase 3
• Efficacy of Varenicline on Smoking Cessation at the Acute Phase of an Exacerbation of Chronic Obstructive Pulmonary DiseaseCompletedNCT01694732Phase 3
• The Effect of Varenicline on D2/D3 Receptor Binding in SmokersCompletedNCT01632189Not applicable
• Varenicline on Reward Responses and Cognition in Adolescent SmokersCompletedNCT01624428Phase 1
• Reducing Cardiovascular Disease by Combining Smoking Cessation Pharmacotherapy and Behavioural CounselingCompletedNCT01623505Phase 4
• Varenicline as a Treatment for Methamphetamine DependenceCompletedNCT01571167Phase 1
• Smoking Habits and Smoking Cessation in Young AdultsCompletedNCT01531049Phase 2/3
• Sympathovagal Balance in Smoking CessationCompletedNCT01474265Phase 4
• Varenicline in Combination With Nicotine Replacement Therapy for Smoking CessationCompletedNCT01444131Phase 2
• Pilot Study of Varenicline to Treat Opioid DependenceCompletedNCT01436474Phase 1

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