Tyrosine Kinase Inhibitors: all 10,744 studies that test it
Page 93 of 108. Open to participants first (1,949), then studies with results posted, then the rest; newest registration first within each.
- Study of BKM120 or BYL719 and Capecitabine in Patients With Metastatic Breast CancerCompletedNCT01300962Phase 1
- Study of PHA-848125AC in Adult Patients With Advanced/Metastatic Solid TumorsCompletedNCT01300468Phase 1
- Imatinib in KIT-negative Systemic MastocytosisCompletedNCT01297777Phase 4
- A Study to Investigate the Safety and Efficacy of AT13387, Alone or in Combination With Imatinib, in Patients With GISTCompletedNCT01294202Phase 2
- Gefitinib Combined With Radiotherapy in Elderly Patients With Esophageal CancerStatus unknownNCT01291823Phase 2
- Exploratory Lapatinib (Positron Emission Tomography) PET Study in Subjects With Breast CancerCompletedNCT01290354Phase 1
- Apatinib in the Treatment of Advanced Non-squamous Non-small Cell Lung CancerStatus unknownNCT01287962Phase 3
- A Study of LY2875358 in Participants With Advanced CancerCompletedNCT01287546Phase 1
- A Pharmacokinetic Study to Access How the Body Absorbs and Removes Linifanib in Male Patients With Advanced Solid Tumors.TerminatedNCT01286974Phase 1
- Use of Individual Pharmacokinetically (PK)-Guided Sunitinib Dosing: A Feasibility Study in Patients With Advanced Solid TumorsCompletedNCT01286896Phase 1
- A Study of LY2801653 in Advanced CancerCompletedNCT01285037Phase 1
- Healthy Volunteers, Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] AZD8931CompletedNCT01284595Phase 1
- Study of an Investigational Drug, ASP3026, in Patients With Advanced Malignancies (Solid Tumors and B-Cell Lymphoma)CompletedNCT01284192Phase 1
- Study of Oral Lucitanib (E-3810), a Dual VEGFR-FGFR Tyrosine Kinase Inhibitor, in Patients With Solid TumorsCompletedNCT01283945Phase 1/2
- Lapatinib and RAD-001 for HER2 Positive Metastatic Breast CancerStatus unknownNCT01283789Phase 2
- Lapatinib Ditosylate and Akt Inhibitor MK2206 in Treating Women With Metastatic Breast CancerTerminatedNCT01281163Phase 1
- Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-KitTerminatedNCT01280565Phase 3
- Study to Evaluate Nilotinib in Adult Patients With Imatinib-resistant or Imatinib-intolerant Chronic Myelogenous Leukemia (CML), or Relapse/Refractory Ph+ Acute Lymphoblastic Leukemia (ALL) (Extension Study)CompletedNCT01279473Phase 1/2
- First-in-Human Single Ascending and Multiple Dose of GLPG0778CompletedNCT01278108Phase 1
- Effects of Administration of Fostamatinib on Blood Concentrations of an Oral Contraceptive in Healthy Female SubjectsCompletedNCT01276262Phase 1
- Sorafenib Tosylate and Stereotactic Radiosurgery in Treating Patients With Brain MetastasesCompletedNCT01276210Phase 1
- Neoadjuvant Combined Endocrine and HER2 Target Therapy in Postmenopausal Women With ER and Her2 Positive Breast CancerCompletedNCT01275859Phase 2
- Axitinib as Second-line Treatment for Advanced Hepatocellular CarcinomaCompletedNCT01273662Phase 2
- Glivec® Plus m-FOLFOX Avastin® in Advanced Colorectal CancerTerminatedNCT01271166Phase 1
- Safety of CHIR-258 (TKI258) in Advanced Solid TumorsTerminatedNCT01270906Phase 1
- Tasigna Neoadjuvant Gastrointestinal Stromal Tumor (GIST)WithdrawnNCT01270893Phase 2
- Whole Soy and Daidzein on Reduction of Blood Pressure in Postmenopausal Chinese WomenStatus unknownNCT01270737Not applicable
- A Study of Apatinib in Patients With Advanced Non-squamous and Non-small Cell Lung CancerCompletedNCT01270386Phase 2
- Efficacy of NF-kB Inhibition for Reducing Symptoms During Maintenance Therapy in Multiple Myeloma PatientsWithdrawnNCT01269203Phase 2
- Perioperative Imatinib Mesylate in Treating Patients With Locally Advanced Gastrointestinal Stromal TumorCompletedNCT01267695Phase 2
- Masitinib in Patients With Mastocytosis With Handicap and Bearing the D816V MutationCompletedNCT01266369Phase 2
- Study of Everolimus and Sorafenib in Patients With Advanced Thyroid Cancer Who Progressed on Sorafenib AloneStatus unknownNCT01263951Phase 2
- A Safety and Efficacy Study of SB1518 for the Treatment of Advanced Lymphoid MalignanciesCompletedNCT01263899Phase 2
- Cediranib as Palliative Treatment in Patients With Symptomatic Malignant Ascites or Pleural EffusionTerminatedNCT01262612Phase 2
- Study of Oxaliplatin and Sorafenib Combination to Treat Gastric Cancer Relapsed After a Cisplatin Based TreatmentCompletedNCT01262482Phase 2
- Evaluating Lapatinib + Capecitabine in Patients Aged 70 and Over With HER2 Metastatic Breast Cancer.CompletedNCT01262469Phase 2
- Clinical Trial Investigating Pazopanib in Patients With Platinum-resistant Advanced Ovarian CancerCompletedNCT01262014Phase 2
- Study of Nilotinib Efficacy in Pigmented Villo-Nodular Synovitis/ Tenosynovial Giant Cell Tumour (PVNS/TGCT)CompletedNCT01261429Phase 2
- Clinical Study of Sorafenib and Zoledronic Acid to Treat Advanced HCCStatus unknownNCT01259193Phase 2
- A Study of AMG 337 in Subjects With Advanced Solid TumorsCompletedNCT01253707Phase 1
- Nilotinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell TransplantationCompletedNCT01252017Phase 2
- A Study of ARQ 197 in Combination With ErlotinibCompletedNCT01251796Phase 1
- BIBF 1120 in Recurrent Glioblastoma MultiformeCompletedNCT01251484Phase 2
- Nasopharyngeal Carcinoma (NPC) AxitinibCompletedNCT01249547Phase 2
- A Study of Fostamatinib in Subjects With Impaired Kidney FunctionCompletedNCT01245790Phase 1
- A Phase 0 of Neoadjuvant Lapatinib in Infiltrative Bladder Carcinoma Before CystectomyTerminatedNCT01245660Early Phase 1
- Akt Inhibitor MK2206 in Combination With Lapatinib Ditosylate in Patients With Advanced or Metastatic Solid Tumors or Breast CancerCompletedNCT01245205Phase 1
- Study of FP-1039 in Subjects With Endometrial CancersWithdrawnNCT01244438Phase 2
- Sunitinib Malate and Bevacizumab in Treating Patients With Kidney Cancer or Advanced Solid MalignanciesCompletedNCT01243359Phase 1
- Study of Crenolanib for the Treatment of Patients With Advanced GIST With the D842-related Mutations and Deletions in the PDGFRA GeneCompletedNCT01243346Phase 2
- E7080 Food Effect Study in Healthy SubjectsCompletedNCT01240408Phase 1
- Phase I/II Study of Pazopanib and Cyclophosphamide in Patients With Platinum-resistant Recurrent Ovarian CancerCompletedNCT01238770Phase 1/2
- Sunitinib + Docetaxel as Second-line Treatment in Gastric CancerCompletedNCT01238055Phase 2
- Dose Finding Study for Combination of Capecitabine, Lapatinib and Vinorelbine in Metastatic Breast CancerTerminatedNCT01238029Phase 1
- Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)CompletedNCT01236638Phase 2
- A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome.CompletedNCT01236144Phase 1/2
- A Phase 1b, Open-label, Dose-finding Study of AMG 706 in Combination With Gemcitabine and Erlotinib to Treat Subjects With Solid TumorsCompletedNCT01235416Phase 1
- Dasatinib and Gemcitabine Hydrochloride or Gemcitabine Hydrochloride Alone in Treating Patients With Pancreatic Cancer Previously Treated With SurgeryCompletedNCT01234935Phase 2
- Bafetinib in Treating Patients With Recurrent High-Grade Glioma or Brain MetastasesCompletedNCT01234740Phase 1
- Bosutinib In Subjects With Renal ImpairmentCompletedNCT01233882Phase 1
- Carboplatin and Paclitaxel With or Without Cediranib Maleate in Treating Patients With Metastatic or Recurrent Cervical Cancer That Cannot Be Removed by SurgeryCompletedNCT01229930Phase 2
- Avastin and Chemotherapy Followed by a KRAS Stratified Randomization to Maintenance Treatment for First Line Treatment of Metastatic Colorectal Cancer.CompletedNCT01229813Phase 3
- Study of Crenolanib, a Selective and Potent Inhibitor of PDGFR, for the Treatment of Adult GliomasTerminatedNCT01229644Phase 2
- A Study Comparing Imatinib and Imatinib/Pegylated Interferon in Chronic Myeloid LeukemiaCompletedNCT01227356Phase 2
- Imatinib Mesylate With or Without Hydroxychloroquine in Treating Patients With Chronic Myeloid LeukemiaStatus unknownNCT01227135Phase 2
- A Study Of Tasocitinib In Dry Eye SubjectsWithdrawnNCT01226680Phase 2
- A Study of Linifanib (ABT-869) in Combination With Carboplatin/Paclitaxel in Japanese Subjects With Non-Small Cell Lung Cancer (NSCLC)CompletedNCT01225302Phase 1
- Single and Multiple Oral Administration Study of ASP015K in Healthy Nonelderly VolunteersCompletedNCT01225224Phase 1
- Curcumin to Prevent Complications After Elective Abdominal Aortic Aneurysm (AAA) RepairCompletedNCT01225094Phase 2/3
- To Evaluate the Effects of Multiple Doses of Nilotinib on the Pharmacokinetics and Metabolism of Midazolam in CML Patients With Additional Extension Phase to Evaluate the Safety of NilotinibCompletedNCT01223898Phase 1
- Cisplatin, Gemcitabine Hydrochloride, and Sorafenib Tosylate in Treating Patients With Transitional Cell Cancer of the BladderStatus unknownNCT01222676Phase 2
- A Study of Fostamatinib in Subjects With Impaired Hepatic (Liver) FunctionCompletedNCT01222455Phase 1
- Safety and Efficacy Study of Nilotinib Combined With Mitoxantrone, Etoposide, and High-dose Cytarabine Induction Chemotherapy Followed by Consolidation for Patients With C-kit Positive Acute Myeloid LeukemiaTerminatedNCT01222143Phase 1/2
- Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)SuspendedNCT01222013Phase 2
- Pazopanib/DCE-MRIs in Renal Cell Carcinoma (RCC)CompletedNCT01221506Early Phase 1
- Phase II Study for Safety and Efficacy Evaluation of Imatinib Mesylate in Children With Chronic Myeloid Leukemia (CML) Philadelphia Chromosome-positive (Ph+)Status unknownNCT01221376Phase 2
- Study of Erlotinib (Tarceva®) in Combination With OSI-906 in Patients With Advanced Non-small Cell Lung Cancer (NSCLC) With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) GeneCompletedNCT01221077Phase 2
- Determining the Maximum Tolerated Dose of Low Dose Interferon-alpha in Conjunction With Nilotinib in Pretreated Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP)CompletedNCT01220648Phase 1
- Trial Of Sunitinib In Advanced Non-Clear Cell Type Renal Cell CarcinomaStatus unknownNCT01219751Phase 2
- A Phase I Study of AZD1480 in Patients With Advanced Solid Malignancies and Advanced Hepatocellular Carcinoma in the Escalation Phase,Non-Small Cell Lung Cancer(NSCLC) and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour in the Expansion Phase.TerminatedNCT01219543Phase 1
- Lapatinib and WBRT for Patients With Brain Metastases From Lung or Breast TumorsCompletedNCT01218529Phase 2
- Intravitreal Pegaptanib in Treatment of Choroidal Neovascularisation Secondary to Pathologic MyopiaWithdrawnNCT01218230Not applicable
- Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START TrialActive, not recruitingNCT01217931Phase 2
- Erlotinib as Neoadjuvant Treatment in Patients With Stage ⅢA N2 NSCLC With Activating EGFR Mutation.CompletedNCT01217619Phase 2
- Trial of Single Agent Sunitinib for Patients With Chemo-refractory Metastatic MelanomaTerminatedNCT01216657Phase 2
- Resection of Pulmonary Metastasis in Clear Cell Renal Cell Carcinoma +/-Adjuvant Sunitinib Therapy (SMAT)TerminatedNCT01216371Phase 2
- An Exploratory Study of High-dose Glivec in Patients With CML-CP Using Molecular EndpointsCompletedNCT01216085Phase 2
- Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate CancerCompletedNCT01215799Phase 2
- Predictive Biomarkers of Response to Sunitinib in the Treatment of Poorly-differentiated NEURO-Endocrine TumorsTerminatedNCT01215578Phase 2
- Study of Sunitinib in Patients With Advanced/Inoperable Fibrolamellar CarcinomaTerminatedNCT01215565Phase 2
- Sorafenib in Urothelium Cancer of BladderTerminatedNCT01215266Phase 2
- Comparing Efficacy of Sorafenib Versus Sorafenib in Combination With Low-dose FP in Patients With Advanced HCCStatus unknownNCT01214343Phase 3
- Study to Assess Safety and Tolerability of AZD4547 in Japanese PatientCompletedNCT01213160Phase 1
- Standard Chemotherapy With of Without Axitinib in Malignant MesotheliomaCompletedNCT01211275Phase 1/2
- A Cardiac Safety Study of Tivozanib to Evaluate the Electrocardiogram and Pharmacokinetic-Electrocardiogram Dynamics in Subjects With Advanced Solid TumorsCompletedNCT01210846Phase 1
- Sunitinib as Maintenance Therapy in Treating Patients With Stage III or Stage IV Non-Small Cell Lung CancerStatus unknownNCT01210053Phase 2
- Study in Healthy Males to Assess Bioavailability of 4 Different Fostamatinib TabletsCompletedNCT01208155Phase 1
- Pazopanib Hydrochloride or a Placebo in Treating Patients With Non-Small Cell Lung Cancer Who Have Received First-Line ChemotherapyTerminatedNCT01208064Phase 2/3
- Tasigna in Glivec-resistant or Intolerant Patients in CMLCompletedNCT01206088Phase 4
- Lapatinib or Trastuzumab Given Prior to Surgery With Chemotherapy in Patients With Early Breast CancerWithdrawnNCT01205217Phase 2