Tyrosine Kinase Inhibitors: all 10,744 studies that test it
Page 89 of 108. Open to participants first (1,949), then studies with results posted, then the rest; newest registration first within each.
- Lapatinib+Vinorelbine vs Vinorelbine HER2 Positive Metastatic Breast Cancer Progressed After Lapatinib/TrastuzumabStatus unknownNCT01730677Phase 2
- A Study to Find the Maximum Tolerated Dose of the Experimental Combination of the Drugs INC424 and BKM120 in Patients With Primary or Secondary MyelofibrosisTerminatedNCT01730248Phase 1
- Gemcitabine Plus Erlotinib in RASH-positive Patients With Metastatic Pancreatic CancerStatus unknownNCT01729481Phase 2
- Afatinib as Cancer Therapy for Exocrine Pancreatic TumoursStatus unknownNCT01728818Phase 2
- Dacomitinib (PF-00299804) in Advanced/Metastatic Squamous Cell Carcinoma of the PenisCompletedNCT01728233Phase 2
- A Phase I/II Study of Tivozanib and Erlotinib as Initial Treatment for Metastatic Non-small Cell Lung Cancer Assigned by VeriStrat® Serum Proteomic EvaluationWithdrawnNCT01728181Phase 1/2
- Study of REGN1400 Alone and in Combination With Erlotinib or Cetuximab in Patients With Certain Types of CancerCompletedNCT01727869Phase 1
- A Study to Assess the Effect of Food on the Bioavailability of the IGF-1R Inhibitor AXL1717 in Patients With Advanced Malignant TumorsCompletedNCT01725555Phase 1
- Assess the Pharmacokinetics of Rosuvastatin and Simvastatin When Administered Alone or in Combination With FostamatinibCompletedNCT01725230Phase 1
- Tivantinib in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT01725191Phase 1
- Study of Frontline Dasatinib Plus Chemotherapy in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (PH+ALL)CompletedNCT01724879Phase 2
- Icotinib or Whole Brain Irradiation in EGFR-mutant Lung CancerCompletedNCT01724801Phase 3
- Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM)CompletedNCT01724606Phase 1
- A Phase I Multiple Ascending Dose Study of ASLAN002 in Subjects With Advanced or Metastatic Solid TumoursCompletedNCT01721148Phase 1
- Increased Dose of Icotinib in Advanced None Small Cell Lung Cancer Patients After Routine Gefitinib TherapySuspendedNCT01720901Phase 4
- Dovitinib for Gastric Cancer With FGFR2 Amplification: GASDOVI-1CompletedNCT01719549Phase 2
- Icotinib Versus First-line Chemotherapy Plus Maintenance Treatment in EGFR Positive Lung Adenocarcinoma PatientsCompletedNCT01719536Phase 3
- Docetaxel, Gemcitabine and Pazopanib as Treatment for Soft Tissue SarcomaCompletedNCT01719302Phase 1/2
- NOV120101 Phase 2 Study in NSCLC Patients With Aquired Resistance to 1st Generation EGFR Tyrosine Kinase InhibitorsCompletedNCT01718847Phase 2
- A Study of Sunitinib in Patients With Advanced CholangiocarcinomaCompletedNCT01718327Phase 2
- Trial of Panitumumab Cisplatin, Fluourouracil and Docetaxel in Locally Advanced or Metastatic Gastric CancerTerminatedNCT01716546Phase 1/2
- Pazopanib Plus Cetuximab for Incurable Head and Neck Squamous Cell Carcinoma (HNSCC)CompletedNCT01716416Phase 1
- Dose Escalation Study Investigating Everolimus and Dovitinib in Metastatic Clear Cell Renal CancerCompletedNCT01714765Phase 1
- Dabrafenib and Pazopanib Hydrochloride in Treating Patients With Advanced Malignant TumorsCompletedNCT01713972Phase 1
- Pazopanib in Relapsed and Refractory Small Cell Lung CancerCompletedNCT01713296Phase 2
- A Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With CrizotinibCompletedNCT01712217Phase 1/2
- A Study to Evaluate the Long-term Safety and Efficacy of ASP015K in Subjects Previously Enrolled in a Phase 2 ASP015K Rheumatoid Arthritis StudyCompletedNCT01711814Phase 2
- Icotinib in Combination With Chemotherapy Versus Chemotherapy Alone in Patients Progressed After Icotinib TreatmentStatus unknownNCT01707329Phase 2
- Akt Inhibitor MK2206, Lapatinib Ditosylate, and Trastuzumab in Treating Patients With Locally Advanced or Metastatic HER2-Positive Breast , Gastric, or Gastroesophageal Cancer That Cannot Be Removed By SurgeryTerminatedNCT01705340Phase 1
- A Study to Evaluate the Bruton's Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Patients With Recurrent Mature B-Cell NeoplasmsCompletedNCT01704963Phase 1
- A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Adult Participants With Advanced or Refractory Solid Tumors or LymphomaCompletedNCT01703481Phase 1
- Activity of Sorafenib in Salivary Gland CancerCompletedNCT01703455Phase 2
- Evaluation Of The Potential Effect That The Administration Of Food Or Antacid Medication May Have In The Oral Absorption Of Dacomitinib (PF-00299804)CompletedNCT01702506Phase 1
- Phase I Study to Assess the Safety, Tolerability, and Pharmacokinetics of Orally Administered CUDC-101 in Cancer PatientsTerminatedNCT01702285Phase 1
- Ruxolitinib in Combination With Nilotinib in Chronic Myeloid Leukemia (CML) PatientsCompletedNCT01702064Phase 1
- Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid Tumors.CompletedNCT01700270Phase 1
- Trial of Lapatinib and Weekly Paclitaxel for Advanced Urothelial CancerWithdrawnNCT01700010Phase 2
- Effect of Tivantinib on the QTC Interval in Cancer SubjectsCompletedNCT01699061Phase 1
- A Phase I Study of Oral BGJ398 in Asian PatientsCompletedNCT01697605Phase 1
- Masitinib in Patients With Gastrointestinal Stromal Tumour After Progression With ImatinibCompletedNCT01694277Phase 3
- Phase 2 Study in Japanese Patients With Intermediate-2 or High Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, Post-Essential Thrombocythemia Myelofibrosis With SplenomegalyCompletedNCT01692366Phase 2
- Safety and Pharmacokinetics of AVL-292 Following Multiple Doses and the Effect of Food on the Single-dose Pharmacokinetics of AVL-292CompletedNCT01692184Phase 1
- Dose Escalation of Icotinib in Advanced Non-small Cell Lung Carcinoma (NSCLC) Patients Evaluated as Stable DiseaseStatus unknownNCT01690390Phase 2
- Nilotinib-Chemotherapy in CML Myeloid BP or Bcr-abl(+) AMLStatus unknownNCT01690065Phase 2
- Phase II Trial of Double Dose of Icotinib in Treating Brain Metastases From Non-small Cell Lung CancerStatus unknownNCT01688713Phase 2
- A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of GSK2586184 and the Effect of Food and GenderCompletedNCT01687309Phase 1
- A Phase I Study to Compare 3 Different Strengths of an Extended Release Formulation of ASP015K to an Immediate Release Formulation of ASP015KCompletedNCT01686217Phase 1
- Abiraterone Acetate and Prednisone With or Without Dasatinib in Treating Patients With Metastatic Hormone-Resistant Prostate CancerStatus unknownNCT01685125Phase 2
- Pazopanib Hydrochloride and Bevacizumab in Treating Patients With Previously Untreated Metastatic Kidney CancerActive, not recruitingNCT01684397Phase 1/2
- An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Vinorelbine in Elderly Patients With Advanced Non Small Lung Cell Cancer - Stage IV (VENUS-1)CompletedNCT01684111Phase 1
- An Dose Escalation Trial of Oral BIBF 1120 in Combination With Intravenous Carboplatin and Vinorelbine in Elderly Patients With Advanced Non-Small Cell Lung Cancer - Stage IV (VENUS-2)CompletedNCT01683682Phase 1
- Erlotinib in Post Radical Operation NSCLC Patients With EGFR MutationStatus unknownNCT01683175Phase 2
- Sorafenib and Topotecan in Refractory/Recurrent Pediatric MalignanciesCompletedNCT01683149Phase 1
- Dovitinib Combined With Bortezomib and Dexamethasone for Relapsed/Refractory Multiple MyelomaWithdrawnNCT01680796Phase 1
- A Phase II Study of Dovitinib in Recurrent and/or Metastatic Adenoid Cystic Carcinoma of the Salivary GlandsCompletedNCT01678105Phase 2
- A Study to Determine the Absorption, Metabolism, and Routes of Excretion of (14C) Radiolabeled Ibrutinib in Healthy Male ParticipantsCompletedNCT01674322Phase 1
- Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous LeukemiaWithdrawnNCT01670084Phase 2
- Dose-ranging Study With GLPG0634 in Methotrexate-refractory Active Rheumatoid Arthritis PatientsCompletedNCT01668641Phase 2
- A Phase I Study of AZD0424 Alone and in Combination in Advanced Solid TumoursTerminatedNCT01668550Phase 1
- Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver CancerCompletedNCT01666756Phase 1
- NOA-12: BIBF1120 and R-RT in GlioblastomaTerminatedNCT01666600Phase 1/2
- Single-center Investigator Initiated Pilot Study Investigating the Tumor Response of Squamous Cell Carcinoma Lesions in Patients Under Lapatinib TreatmentTerminatedNCT01666431Phase 2
- Pilot Study Investigating the Metabolic Activity and Transcriptional Profiling in Vivo in Tumor Biopsies in Melanoma Patients During Treatment With Pazopanib Alone and in Combination With PaclitaxelCompletedNCT01666418Phase 2
- Single and Multiple Dose Pharmacokinetics of GLPG0634 in Elderly Healthy SubjectsCompletedNCT01665924Phase 1
- Icotinib as First-line and Maintenance Treatment in EGFR Mutated Patients With Lung AdenocarcinomaStatus unknownNCT01665417Phase 4
- Effects of Genistein in Postmenopausal Women With Metabolic SyndromeCompletedNCT01664650Phase 2/3
- Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT01660971Phase 1
- Phase II Study of Docetaxel +/- Nintedanib in Breast CancerCompletedNCT01658462Phase 2
- ErbB2 Positive Metastatic Breast CancerTerminatedNCT01658358Phase 1/2
- Phase I, Dose Escalation of SAR125844 in Asian Solid Tumor PatientsCompletedNCT01657214Phase 1
- Study of ARQ 197 in Hepatocellular Carcinoma (HCC)CompletedNCT01656265Phase 1
- Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid TumorsCompletedNCT01654965Phase 1
- A Study of Famitinib Malate in HER2-negative Metastatic Breast CancerCompletedNCT01653574Phase 2
- A Study of Apatinib in Non-triple-negative Metastatic Breast CancerCompletedNCT01653561Phase 2
- Study of Erlotinib and Metformin in Triple Negative Breast CancerCompletedNCT01650506Phase 1
- A Study to Evaluate the Efficacy and Safety of ASP015K in Moderate to Severe Rheumatoid Arthritis SubjectsCompletedNCT01649999Phase 2
- First-line Treatment With Icotinib in Elder NSCLC EGFR Mutated PatientsStatus unknownNCT01646450Phase 4
- Phase I Study of Fruquintinib(HMPL-013) in Patients With Advanced Solid TumorsCompletedNCT01645215Phase 1
- Weekly Paclitaxel With or Without Pazopanib in Platinum Resistant or Refractory Ovarian CancerCompletedNCT01644825Phase 2
- Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)CompletedNCT01644773Phase 1
- Phase 1b Safety and Efficacy Study of TRU-016TerminatedNCT01644253Phase 1
- Ruxolitinib and Pomalidomide Combination Therapy in Patients With Primary and Secondary MFCompletedNCT01644110Phase 1/2
- Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic MalignanciesTerminatedNCT01643603Phase 1
- Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are MetastaticCompletedNCT01643278Phase 1
- Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG CriteriaTerminatedNCT01642017Phase 1
- Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.CompletedNCT01641107Phase 2
- Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients With Advanced Breast and Gastrointestinal TumorsCompletedNCT01640665Phase 1
- Phase I Study of MLN8237 and Pazopanib in Patients With Solid TumorsCompletedNCT01639911Phase 1
- Phase 2 Study - Aurora + Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced + Metastatic TNBCCompletedNCT01639248Phase 2
- Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.CompletedNCT01636908Not applicable
- Dovitinib in Neuroendocrine TumorsCompletedNCT01635907Phase 2
- Study of Safety and Preliminary Efficacy for LDK378 in Japanese Patients With Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)CompletedNCT01634763Phase 1
- A Study of Escalating Doses of Itacitinib Administered Orally in Patients With Plaque PsoriasisCompletedNCT01634087Phase 2
- An Open Label Study of Itacitinib Administered Orally in Patients With MyelofibrosisCompletedNCT01633372Phase 2
- A Dose Escalation Trial of PR610 Treating Patients With Solid TumorsTerminatedNCT01631279Phase 1/2
- A Single-Dose Study of Tivozanib in Subjects With Hepatic Impairment and Normal Hepatic FunctionCompletedNCT01631097Phase 1
- Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop TrialStatus unknownNCT01627132Phase 2
- A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Ibrutinib in Healthy ParticipantsCompletedNCT01626651Phase 1
- A Study Exploring the Safety, Tolerability, and Efficacy of a 28 Day Course Followed by an Additional 56 Day Course of Itacitinib in Subjects With Active Rheumatoid ArthritisCompletedNCT01626573Phase 2
- Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by SurgeryCompletedNCT01625156Phase 1