Tyrosine Kinase Inhibitors: all 10,744 studies that test it
Page 88 of 108. Open to participants first (1,949), then studies with results posted, then the rest; newest registration first within each.
- Phase II Study of Dovitinib for FGFR1 Amplified Squamous Non-small Cell Lung CancerStatus unknownNCT01861197Phase 2
- Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid TumorsCompletedNCT01859858Phase 1
- A Phase I/IB Trial of MEK162 in Combination With Erlotinib in NSCLC Harboring KRAS or EGFR MutationCompletedNCT01859026Phase 1
- Safety Study of Itacitinib (INCB039110) in Combination With Gemcitabine and Nab-Paclitaxel in Subjects With Advanced Solid TumorsCompletedNCT01858883Phase 1/2
- Nilotinib 300 mg BID in Newly Diagnosed CP-CML Patients to Verify Disappearance of CD34+/Lin-Ph+ CellsCompletedNCT01856283Phase 2
- Second-line Treatment With Icotinib in Esophageal Carcinoma Patients With EGFR Overexpression (IHC 3+) or Positive FISHCompletedNCT01855854Phase 2
- Regorafenib in Subjects With Metastatic Colorectal Cancer (mCRC) Who Have Progressed After Standard TherapyCompletedNCT01853319Phase 3
- Sorafenib and Temsirolimus in Treating Patients With Metastatic, Recurrent, or Unresectable MelanomaWithdrawnNCT01851408Phase 2
- Sequential Use of Low-dose Sunitinib With Chemotherapy in Advanced NSCLC After Failure of Conventional RegimenStatus unknownNCT01850147Phase 2
- Phase I Dose Escalation Study of VS-4718 in Subjects With Metastatic Non-Hematologic MalignanciesTerminatedNCT01849744Phase 1
- Phase I Study With Sorafenib in Addition to Vinflunine in Metastatic Transitional Cell Carcinoma of the Urothelial TractCompletedNCT01844947Phase 1
- Neoadjuvant Therapy of Icotinib in Epidermal Growth Factor Receptor Mutated NSCLC PatientsStatus unknownNCT01843647Phase 2
- Ibrutinib in Treating Patients With Relapsed Hairy Cell LeukemiaActive, not recruitingNCT01841723Phase 2
- Sorafenib Plus Doxorubicin in Patients With Advanced Hepatocellular Carcinoma With Disease Progression on SorafenibActive, not recruitingNCT01840592Phase 2
- Effect of SAR302503 on ECG Activity in Patients With Solid TumorsCompletedNCT01836705Phase 1
- Afatinib In Combination With Cisplatin Or Carboplatin + Pemetrexed In Patients With EGFR-Mutant Lung Cancers Undergoing Definitive ChemoradiationWithdrawnNCT01836341Phase 1
- First-in-Human Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of Janus Kinase-1 Inhibitor PF-04965842 in Healthy Western and Japanese SubjectsCompletedNCT01835197Phase 1
- Cabozantinib-S-Malate and Vemurafenib in Treating Patients With Solid Tumors or Melanoma That is Metastatic or That Cannot Be Removed By SurgeryTerminatedNCT01835184Phase 1
- Tivozanib + Gemcitabine in Metastatic RCCWithdrawnNCT01834183Phase 2
- A Phase I Study of Anlotinib on Tolerance and PharmacokineticsCompletedNCT01833923Phase 1
- Preoperative Gefitinib for EGFR Mutant II-IIIa NSCLC (ECTOP-1001)CompletedNCT01833572Phase 2
- Effect of Oral Supplementation With Curcumin (Turmeric) in Patients With Proteinuric Chronic Kidney DiseaseCompletedNCT01831193Phase 3
- A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid ArthritisCompletedNCT01830985Phase 2/3
- A Study of Famitinib in Patients With Advanced Metastatic Renal Cell CancerCompletedNCT01829841Phase 2
- Rituximab, Lenalidomide, and Ibrutinib in Treating Patients With Previously Untreated Stage II-IV Follicular LymphomaActive, not recruitingNCT01829568Phase 1
- Study of Dasatinib, Androgen Deprivation Therapy and RadiationWithdrawnNCT01826838Phase 1
- Sunitinib® in Patients With Recurrent Ovarian Clear Cell CarcinomaCompletedNCT01824615Phase 2
- Vandetanib in Advanced NSCLC With RET RearrangementCompletedNCT01823068Phase 2
- A Study to Determine the Effect of Food on the Pharmacokinetics of PCI-32765CompletedNCT01820936Phase 1
- NOV120101 (Poziotinib) for 1st Line Monotherapy in Patients With Lung AdenocarcinomaTerminatedNCT01819428Phase 2
- Low-dose Nilotinib and Imatinib Combination in Chronic Myeloid Leukemia Patients, With Failure, Suboptimal Response or Treatment IntoleranceCompletedNCT01819389Phase 3
- Phase II Study of the Optimal Scheme of Administration of Pazopanib in Thyroid CarcinomaCompletedNCT01813136Phase 2
- Curcumin and Yoga Therapy for Those at Risk for Alzheimer's DiseaseStatus unknownNCT01811381Phase 2
- Phase I/II for Safety and Efficacy of Nilotinib in a Population Steroid-refractory/or Steroid-dependent cGVHDCompletedNCT01810718Phase 1
- De- Escalation and Stopping Treatment of Imatinib, Nilotinib or sprYcel in Chronic Myeloid LeukaemiaCompletedNCT01804985Phase 2
- A Long-term Extension Study of PCI-32765 (Ibrutinib)Active, not recruitingNCT01804686Phase 3
- Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid TumorsTerminatedNCT01804530Phase 1
- Phase II Open Label, Non-randomized Study of Sorafenib and Everolimus in Relapsed and Non-resectable OsteosarcomaCompletedNCT01804374Phase 2
- Docetaxel With or Without Low-dose, Short Course Sunitinib in Refractory Solid TumorsStatus unknownNCT01803503Phase 2
- Dasatinib in Patients With Chronic Myeloid Leukemia in Chronic PhaseStatus unknownNCT01802450Phase 2
- A Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) Plus Sorafenib in Patients With Unresectable Hepatocellular Carcinoma (HCC)WithdrawnNCT01801163Phase 1
- A Phase I, Open Interaction Study Between GLPG0634 and Midazolam in Healthy SubjectsCompletedNCT01798979Phase 1
- A Phase II Study of Axitinib in Metastatic Non-clear Cell Renal Cell Carcinoma Patients Previously Treated With TemsirolimusCompletedNCT01798446Phase 2
- Pazopanib Maintenance for SCLCCompletedNCT01797874Phase 2
- A Study To Assess Absorption Of Study Drug Dacomitinib (PF-00299804), Given As An Oral Tablet Compared To An Intravenous Infusion In Healthy VolunteersCompletedNCT01796327Phase 1
- Proof-of-Concept Study of AZD4547 in Patients With FGFR1 or FGFR2 Amplified TumoursStatus unknownNCT01795768Phase 2
- JAK2 Inhibitors RUXOLITINIB in Patients With MyelofibrosisCompletedNCT01795677Phase 2
- 1st-line Activity of Dovitinib and Correlation With Genetic Changes in RCCStatus unknownNCT01791387Phase 2
- Nintedanib(BIBF1120) in Thyroid CancerCompletedNCT01788982Phase 2
- Ruxolitinib Phosphate and Azacytidine in Treating Patients With Myelofibrosis or Myelodysplastic Syndrome/Myeloproliferative NeoplasmCompletedNCT01787487Phase 2
- Second-line FOLFOX With or Without Regorafenib in mCRC Patients Failed to First-line Irinotecan Plus FluoropyrimidinesWithdrawnNCT01786538Phase 3
- Efficacy Study of Sunitinib and Everolimus (Rotational vs Sequential Arm) in Pats. With m Clear Cell Renal CancerTerminatedNCT01784978Phase 2
- Gefitinib Versus Pemetrexed for Previously Treated NSCLC PatientsCompletedNCT01783834Phase 2
- Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS MetastasisCompletedNCT01783756Phase 1/2
- A Phase II Study of Imatinib Versus Interferon as Adjuvant Therapy in KIT-mutated MelanomaStatus unknownNCT01782508Phase 2
- A Study of PCI-32765 (Ibrutinib) in Patients With Refractory Follicular LymphomaCompletedNCT01779791Phase 2
- Clinical Study of Oral IGF-1R Inhibitor in Subjects With Advanced Refractory Solid TumorsSuspendedNCT01779336Phase 1
- Phase I/Ib Study of Paclitaxel in Combination With VS-6063 in Patients With Advanced Ovarian CancerCompletedNCT01778803Phase 1
- An Adaptive Phase II Study to Evaluate the Efficacy, Pharmacodynamics, Safety and Tolerability of GSK2586184TerminatedNCT01777256Phase 2
- Multicenter Single-arm Pilot Study Evaluating Efficacy of Nilotinib in CML Patients With Molecular Relapse After Glivec Discontinuation Within the Context of the STIM Trials (STIM and STIM2)CompletedNCT01774630Phase 2
- Phase I Study of the Volitinib (HMPL-504) in Patients With Advanced Solid TumorsCompletedNCT01773018Phase 1
- Phase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung CancerCompletedNCT01772797Phase 1
- Tivozanib Before Surgery in Treating Patients With Localized Kidney CancerWithdrawnNCT01769885Not applicable
- A Phase II Study of Single-agent DOVitinib in Advanced Malignant PlEural Mesothelioma Which Has Progressed Following Prior Platinum-Antifolate ChemotherapyTerminatedNCT01769547Phase 2
- A Study to Evaluate the Pharmacokinetics of PCI-32765 in Participants With Varying Degrees of Hepatic ImpairmentCompletedNCT01767948Phase 1
- A Phase IB Study Of The BTKi CC-292 Combined With Lenalidomide In Adults Patients With Relapsed/Refractory B-Cell LymphomaCompletedNCT01766583Phase 1
- Safety,PK/PD, Food Effect Study of Orally Administered HM71224 in Healthy Adult Male VolunteersCompletedNCT01765478Phase 1
- A Study of KX2-391 With Paclitaxel in Patients With Solid TumorsStatus unknownNCT01764087Phase 1/2
- Open Label Pharmacokinetic Study of SAR302503 in Subjects With Renal ImpairmentCompletedNCT01763190Phase 1
- A Study to Assess the Effect of Rifampin on the Pharmacokinetics of PCI-32765 in Healthy ParticipantsCompletedNCT01763021Phase 1
- Open Label Pharmacokinetic Study of SAR302503 in Subjects With Hepatic ImpairmentCompletedNCT01762462Phase 1
- A Study of Famitinib in Patients With Advanced Colorectal CancerCompletedNCT01762293Phase 2
- A Phase I Study of Famitinib Malate in Patients With Solid TumorCompletedNCT01762280Phase 1
- Sorafenib Combined With Chemotherapy for Renal Collecting Duct CarcinomaCompletedNCT01762150Phase 2
- A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal FunctionCompletedNCT01761773Phase 1
- Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the LungTerminatedNCT01759303Phase 2
- Gefitinib or Docetaxel as Second Line Therapy for Wild-type Epidermal Growth Factor Receptor (EGFR) NSCLCStatus unknownNCT01755923Phase 2
- A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 InhibitorCompletedNCT01754935Phase 2
- A Drug Interaction Study to Evaluate the Pharmacokinetics of ASP015K and Methotrexate in Patients With Rheumatoid ArthritisCompletedNCT01754805Phase 1
- Paclitaxel Plus Radiation With Erlotinib to Treat Esophageal Squamous CarcinomaStatus unknownNCT01752205Phase 3
- A Clinical Trial to Compare the Pharmacokinetics of Imatinib Mesylate Tablet 400mg (1 Tablet) and Glivec Film-coated Tablet 100mg (4 Tablets)(Phase I)CompletedNCT01751919Phase 1
- Ruxolitinib in Treating Participants With Chronic Myeloid Leukemia With Minimal Residual Disease While on Therapy With Tyrosine Kinase InhibitorsTerminatedNCT01751425Phase 1
- Efficacy and Safety Curcumin in DepressionCompletedNCT01750359Phase 4
- Tivantinib and Bevacizumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryCompletedNCT01749384Phase 1
- Vinorelbine-ifosfamide Versus Gefitinib for EGFR Gene Mutation Negative Non-small Cell Lung Cancer PatientsStatus unknownNCT01749072Phase 2
- Safety and Efficacy of Oncoxin Plus Surafineb in Hepatocellular CarcinomaStatus unknownNCT01747642Phase 2/3
- A Phase I-II Study of HM781-36B Combined With Paclitaxel and Trastuzumab in HER-2 Positive Advanced Gastric CancerCompletedNCT01746771Phase 1/2
- Adjuvant Afatinib in Stage I-III NSCLC With EGFR MutationStatus unknownNCT01746251Phase 2
- Icotinib at Different Doses in Second-line Treatment for Non-small Cell Lung Cancer Patients With Wild Type EGFRStatus unknownNCT01744925Phase 2
- Dasatinib and Crizotinib in Advanced CancerCompletedNCT01744652Phase 1
- Safety Study of CC-292 and Rituximab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic LymphomaCompletedNCT01744626Phase 1
- Pazopanib in Advanced and Cisplatin-resistant Germ Cell TumorsCompletedNCT01743482Phase 2
- Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the InvestigatorCompletedNCT01742299Phase 4
- A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494CompletedNCT01741493Phase 1
- Dovitinib(TKI258) in Patients With Castration-resistant Prostate CancerCompletedNCT01741116Phase 2
- Ipilimumab and Imatinib Mesylate in Advanced CancerCompletedNCT01738139Phase 1
- Efficacy and Safety Study of Sorafenib to Treat Advanced Medullary Thyroid CarcinomaWithdrawnNCT01736878Phase 2
- Safety Study of CC-292 and Lenalidomide in Subjects With Chronic Lymphocytic Leukemia/ Small Lymphocytic LymphomaCompletedNCT01732861Phase 1
- The Safety and Effects of Gefitinib in Triple-negative,EGFR Positive Metastatic Breast CancerStatus unknownNCT01732276Phase 2
- A Study of Sunitinib Versus Placebo in Combination With Lanreotide in Patients With Progressive Advanced/Metastatic Midgut Carcinoid TumorsStatus unknownNCT01731925Phase 2