Tyrosine Kinase Inhibitors: all 10,744 studies that test it
Page 87 of 108. Open to participants first (1,949), then studies with results posted, then the rest; newest registration first within each.
- Combined Modality Treatment of Sarcomas of the ExtremitiesCompletedNCT01985295Phase 1
- A Study of Tucatinib (ONT-380) Combined With Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2+ Breast CancerCompletedNCT01983501Phase 1
- Improved Oral Bioavailability of Curcumin Incorporated Into MicellesCompletedNCT01982734Early Phase 1
- Genistein as a Possible Treatment for Alzheimer's Disease.CompletedNCT01982578Not applicable
- A Study of LY2801653 in Healthy ParticipantsCompletedNCT01981408Phase 1
- A Study of the Elimination, Pharmacokinetics, and Metabolism of RO5424802CompletedNCT01981005Phase 1
- IRCI Gynae Sarcomas, High Grade Uterine SarcomaCompletedNCT01979393Phase 2
- Efficacy and Safety Study of CC-292 Versus Placebo as Co-therapy With Methotrexate in Active Rheumatoid ArthritisCompletedNCT01975610Phase 2
- Pilot Study of Curcumin for Women With Obesity and High Risk for Breast CancerCompletedNCT01975363Not applicable
- A Phase Ib Study of Fruquintinib in 3rd Line mCRCCompletedNCT01975077Phase 1/2
- Safety and Pharmacokinetics of Regorafenib and Cetuximab in CombinationCompletedNCT01973868Phase 1
- Study of Icotinib Hydrochloride in Treating Patients With Recurrent or Metastatic Esophageal Cancer After Failure of Conventional ChemotherapyCompletedNCT01973725Phase 2
- Dovitinib (TKI258) in the Treatment of Patients With Relapsed GlioblastomaStatus unknownNCT01972750Phase 1
- A Pharmacokinetic Study in Healthy Participants to Assess the Pharmacokinetics and Safety of a Supratherapeutic Dose of PCI-32765 (Ibrutinib) Capsule and Solution Formulations Administered With FoodCompletedNCT01969266Phase 1
- Low Dose Daily Erlotinib in Combination With High Dose Twice Weekly Erlotinib in Patients With EGFR-Mutant Lung CancerCompletedNCT01967095Phase 1
- Pilot Study of Ruxolitinib in Relapsed or Refractory Hodgkin Lymphoma and Primary Mediastinal Large B-cell LymphomaCompletedNCT01965119Phase 2
- A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-38877618 in Healthy Male ParticipantsCompletedNCT01964872Phase 1
- Effect of Antioxidant Intake on Cardiovascular RiskCompletedNCT01964846Not applicable
- Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular CarcinomaWithdrawnNCT01964235Phase 2
- An Open-label, Multicenter, Phase II Study of LDK378 in Patients With Non-small Cell Lung Cancer Harboring ROS1 RearrangementCompletedNCT01964157Phase 2
- An Open-label, Multicenter, Phase II Study of Dovitinib in Advanced Thyroid CancerCompletedNCT01964144Phase 2
- Evaluation of the High Dose of Icotinib in Advanced Lung Cancer Patients After Failure of Target TherapyStatus unknownNCT01963195Phase 2
- A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-42756493 in Patients With Advanced or Refractory Solid Tumors or LymphomaCompletedNCT01962532Phase 1
- Phase I Trial of Cabozantinib in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT01961765Phase 1
- Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal CancerWithdrawnNCT01960023Phase 1/2
- Drug-Drug Interaction Study Evaluating Effects of ASP015K on RosuvastatinCompletedNCT01959399Phase 1
- A Study of Safety and Effectiveness of JNJ-54781532 in Patients With Moderately to Severely Active Ulcerative ColitisCompletedNCT01959282Phase 2
- Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin LymphomaActive, not recruitingNCT01955499Phase 1
- Erlotinib 100mg qd Versus Gefitinib 250mg qd for EGFR Mutant NsclcStatus unknownNCT01955421Phase 2
- Food Effect Study of Single Dose of Fruquintinib (HMPL-013) in Healthy SubjectsCompletedNCT01955304Phase 1
- A Two-part Study to Investigate the Interaction and Pharmacokinetics of GSK2586184CompletedNCT01953835Phase 1
- To Determine the Maximum Tolerated Dose (MTD) of BIBF 1120 in Patients With Solid TumoursCompletedNCT01951846Phase 1
- Phase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung CancerCompletedNCT01951690Phase 2
- To Determine the Relative Bioavailability of Different Formulations of AZD9291 and the Effect of Food.CompletedNCT01951599Phase 1
- Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung CancerStatus unknownNCT01951469Phase 3
- Effect of Hepatic Impairment on LDK378 PharmacokineticsCompletedNCT01950481Phase 1
- Study to Determine the Efficacy of Regorafenib in Metastatic Colorectal Cancer Patients and to Discover BiomarkersStatus unknownNCT01949194Phase 2
- Debio 1347-101 Phase I Trial in Advanced Solid Tumours With Fibroblast Growth Factor Receptor (FGFR) AlterationsTerminatedNCT01948297Phase 1
- Dabrafenib and Lapatinib in Treating Patients With Refractory Thyroid Cancer That Cannot Be Removed by SurgeryActive, not recruitingNCT01947023Phase 1
- Phase I Trial of Vandetanib Combined With 131I-mIBG to Treat Patients With Advanced Phaeochromocytoma and ParagangliomaWithdrawnNCT01941849Phase 1
- A Dose Escalation Study to Assess Safety of GSK2256098 (FAK Inhibitor) in Combination With Trametinib (MEK Inhibitor) in Subjects With Advanced Solid TumorsCompletedNCT01938443Phase 1
- Study of Pyrotinib in Patients With Human Epidermalgrowth Factor Receptor 2 (HER2) Positive Advanced Breast CancerCompletedNCT01937689Phase 1
- Third-line Treatment of Gefitinib in NSCLC PatientsCompletedNCT01933347Phase 2
- Sorafenib in Liver Function Impaired Advanced Hepatocellular CarcinomaCompletedNCT01932385Phase 2/3
- A Phase Ib Study of Selatinib Ditosilate Tablets in Patients With Advanced Breast CancerStatus unknownNCT01931943Phase 1
- Safety Study of Two Oral Formulations of MGCD265 Administered in Healthy Subjects in the Fasting StateCompletedNCT01930006Phase 1
- Regorafenib Assessment in Refractory Advanced Colorectal Cancer(RegARd-C)CompletedNCT01929616Phase 2
- A Study to Assess the Relative Bioavailability Between Two ASP015K Tablets and the Food Effect of a New Tablet in Healthy Adult SubjectsCompletedNCT01929577Phase 1
- Icotinib as Adjuvant Therapy in Treating Non-small-cell Lung Cancer Patients With Positive EGFR MutationStatus unknownNCT01929200Phase 2
- Phase 1b Trial of BGJ398/BYL719 in Solid TumorsCompletedNCT01928459Phase 1
- Pemetrexed Disodium and Carboplatin or Cisplatin With or Without Erlotinib Hydrochloride in Treating Patient With Stage IV Non-Small Cell Lung Cancer Resistant to First-Line Therapy With Erlotinib Hydrochloride or GefitinibWithdrawnNCT01928160Phase 2
- Adjunctive Curcumin for Symptomatic Adolescents With Bipolar Disorder: Brain and Body ConsiderationsTerminatedNCT01928043Phase 2
- Icotinib With Whole Brain Radiation Therapy in NSCLC Patients With Brain MetastasesStatus unknownNCT01926171Phase 4
- Oral Bioavailability of Curcumin From Micronized Powder and Liquid Micelles in Healthy Young Women and MenCompletedNCT01925287Early Phase 1
- Phase II Study of Anlotinib in Patients With Advanced Non-small Cell Lung Cancer（ALTER0302）CompletedNCT01924195Phase 2
- To Determine the Maximum Tolerated Dose of Oral CEP-37440 in Patients With Advanced or Metastatic Solid TumorsCompletedNCT01922752Phase 1
- Dovitinib Plus Docetaxel in Gastric CancerCompletedNCT01921673Phase 1/2
- ARRY-380 + Trastuzuamab for Breast w/ Brain MetsCompletedNCT01921335Phase 1
- Radiosensitizing and Radioprotectve Effects of Curcumin in Prostate CancerCompletedNCT01917890Not applicable
- OPTIM DASATINIB (Optimized Tyrosine Kinase Inhibitors Monotherapy)CompletedNCT01916785Phase 2
- Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC)CompletedNCT01915602Phase 2
- Phase I/II Study of Nilotinib/Ruxolitinb Therapy for TKI Resistant Ph-LeukemiaCompletedNCT01914484Phase 1/2
- INC280 and Erlotinib Hydrochloride in Treating Patients With Non-small Cell Lung CancerCompletedNCT01911507Phase 1
- Study of INCB040093 in Subjects With Previously Treated B-Cell MalignanciesCompletedNCT01905813Phase 1
- A Study of BI 853520 in Japanese and Taiwanese Patients With Various Types of Advanced or Metastatic CancerCompletedNCT01905111Phase 1
- Randomized Trial Sorafenib-Pravastatin Versus Sorafenib Alone for the Palliative Treatment of Child-Pugh A Hepatocellular CarcinomaCompletedNCT01903694Phase 3
- Phase II Study of Regorafenib in Metastatic Soft Tissue SarcomaCompletedNCT01900743Phase 2
- Imatinib Mesylate and Mycophenolate Mofetil for Steroid-Refractory Sclerotic/Fibrotic cGVHD in ChildrenTerminatedNCT01898377Phase 2
- A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular CarcinomaCompletedNCT01897038Phase 1
- Ruxolitinib for Patients With Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS)CompletedNCT01895842Phase 1
- Study to Evaluate a Pharmacokinetic of HM61713 in Healthy Male SubjectsCompletedNCT01894399Phase 1
- Sorafenib and Radioembolization With Sir-Spheres® for the Treatment of Metastatic Ocular MelanomaCompletedNCT01893099Phase 1
- Study of Tivantinib (ARQ 197) Plus Cetuximab in EGFR Inhibitor-Resistant MET High SubjectsCompletedNCT01892527Phase 2
- Ponatinib in the Treatment of FGFR Mutation Positive Recurrent or Persistent Endometrial CarcinomaWithdrawnNCT01888562Not applicable
- Phase Ⅲ Trial of WBRT Versus Erlotinib Concurrent Whole-brain Radiation Therapy as first-line Treatment for Patients With Multiple Brain Metastases From Non-small-cell Lung Cancer(ENTER): a Multicentre, Open-label, Randomised StudyCompletedNCT01887795Phase 3
- Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young AdultsTerminatedNCT01887522Phase 2
- Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaCompletedNCT01886859Phase 1
- Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male SubjectsCompletedNCT01886209Phase 1
- Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young AdultsCompletedNCT01884922Phase 1
- Ibrutinib and Rituximab in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Older Patients With Newly Diagnosed Mantle Cell LymphomaActive, not recruitingNCT01880567Phase 2
- A Phase II Study of Anlotinib in STS PatientsCompletedNCT01878448Phase 2
- A Phase II Study of Oral JAK1/JAK2 Inhibitor INC424 in Adult Patients With Relapsed/Refractory Classical Hodgkin's LymphomaCompletedNCT01877005Phase 2
- Defining the HER2 Positive (+) Breast Cancer Kinome Response to Trastuzumab, Pertuzumab, Combination Trastuzumab +Pertuzumab, or Combination Trastuzumab + LapatinibCompletedNCT01875666Early Phase 1
- Regorafenib in Frail and/or Unfit for Chemotherapy Patients With Metastatic Colorectal CancerCompletedNCT01875380Phase 2
- A Phase II Study of Anlotinib in MTC PatientsCompletedNCT01874873Phase 2
- Masitinib in Patients With Mild to Moderate Alzheimer's DiseaseCompletedNCT01872598Phase 3
- Combination of Dasatinib and Peg-Interferon Alpha 2b in First Line for Chronic Myeloid Leukemia in Chronic PhaseCompletedNCT01872442Phase 2
- Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified ChemotherapyActive, not recruitingNCT01871766Phase 2
- CIK Cell Transfusion Plus Gefitinib As Second Or Third-Line Treatment for Advanced Adenocarcinoma Non-Small Cell Lung CancerTerminatedNCT01871480Phase 2
- A Phase I Study of Nilontinib and Cetuximab in Patients With Solid TumorsTerminatedNCT01871311Phase 1
- Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural MesotheliomaTerminatedNCT01870609Phase 2
- Nilotinib Plus Pegylated Interferon-α2b in CMLTerminatedNCT01866553Phase 2
- A Study to Assess the Absolute Bioavailability of Oral PCI-32765 and the Effect of Grapefruit Juice on the Bioavailability of PCI-32765 in Healthy ParticipantsCompletedNCT01866033Phase 1
- Combination of Metformin With Gefitinib to Treat NSCLCCompletedNCT01864681Phase 2
- Safety and Tolerability of AZD0530 (Saracatinib) in Alzheimer's DiseaseCompletedNCT01864655Phase 1
- Phase 1 Study of CM082 (X-82) Tablets in Advanced Cancer Patients in ChinaCompletedNCT01863485Phase 1
- Phase I/II Trial of Antagonism of HER in GI CancerCompletedNCT01862003Phase 2
- A Trial Comparing Two Medications as First Treatment in Elderly Patients With Metastatic or Advanced Soft Tissue SarcomaCompletedNCT01861951Phase 2
- Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid LeukemiaActive, not recruitingNCT01861314Phase 1
- Afatinib Plus Nimotuzumb for NSCLCStatus unknownNCT01861223Phase 1/2