Tyrosine Kinase Inhibitors: all 10,479 studies that test it
Page 75 of 105. Open to participants first (1,915), then studies with results posted, then the rest; newest registration first within each.
- Protocol GELLC-7: Ibrutinib Followed by Ibrutinib Consolidation in Combination With OfatumumabStatus unknownNCT03280160Phase 2
- Study Evaluating the Efficacy of Maintenance Olaparib and Cediranib or Olaparib Alone in Ovarian Cancer PatientsStatus unknownNCT03278717Phase 3
- Apatinib in Combination With S-1 as Second-Line Treatment in Patients With Advanced Gastric CancerStatus unknownNCT03276156Phase 1
- Clinical Trial of the Use of the Nasal Spray of Patients With Recurrence of GlioblastomaWithdrawnNCT03275558Phase 1
- Effect of Ruxolitinib on Tumor Infiltrating Myeloid CellsWithdrawnNCT03274778Not applicable
- Efficacy and Safety of Apatinib for Recurrent or Metastatic Esophageal Squamous Cell CarcinomaCompletedNCT03274011Phase 2
- Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive Breast CancerStatus unknownNCT03273595Phase 2
- Apatinib Versus Bevacizumab in Second-line Therapy for Colorectal Cancer(ABST-C)Status unknownNCT03271255Phase 2
- A Study of Apatinib Combined With S1 in Patients With Advanced Gastric CancerStatus unknownNCT03271073Phase 2
- A Study of Apatinib and Tegafur Gimeracil Oteracil in Locally Advanced Squamous Cell Carcinoma of the Head and NeckCompletedNCT03267121Phase 2
- The Effect of BMS-986195 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female PatientsCompletedNCT03262740Phase 1
- The Effect of BMS-986165 Combined With an Oral Contraceptive (Ethinyl Estradiol/Norethindrone) in Healthy Female PatientsCompletedNCT03262727Phase 1
- Efficacy and Safety of Apatinib As Third Line Therapy in Patients With Advanced Ovarian CancerStatus unknownNCT03262545Phase 2
- Adjuvant Therapy With Apatinib for HCC Patients With PVTT Who Underwent Radical ResectionStatus unknownNCT03261791Phase 2
- Study to Evaluate the Safety, Preliminary Efficacy and Pharmacokinetics of 3810Status unknownNCT03260179Phase 1
- Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AMLCompletedNCT03258931Phase 3
- IMRT and Timing in Combination With EGFRTKI for Stage IV Non-small-cell Lung CancerStatus unknownNCT03258671Not applicable
- A Study to Investigate the Effect of Single Dose of AZD6094 (600 mg) on Cardiac Repolarization in Healthy VolunteersCompletedNCT03258515Phase 1
- A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic DermatitisCompletedNCT03257644Phase 1
- Study of AZD9291 in NSCLC Patients Harboring T790M Mutation Who Failed EGFR TKI and With Brain and/or LMSStatus unknownNCT03257124Phase 2
- Compare Apatinib Plus Chemotherapy Drug Versus Chemotherapy Drug as Second-line Treatment in NSCLCTerminatedNCT03256721Phase 2
- Clinical Study on Treatment of Apatinib Mesylate in First-line Maintenance of Advanced Gastric CancerStatus unknownNCT03255811Not applicable
- Study of SHR0302 Tablets (SHR0302) as Monotherapy in Active Rheumatoid Arthritis (RA) PatientsCompletedNCT03254966Phase 2
- A Study to Evaluate BMS-986165 Tablet Formulation Relative to BMS-986165 Capsule Formulation and the Effect of a High-Fat/ High-Calorie Meal and Increased Gastric pH on the BMS-986165 Tablet FormulationCompletedNCT03254784Phase 1
- Vinorelbine Plus Apatinib Versus Vinorelbine in Advanced Triple-Negative Breast CancerCompletedNCT03254654Phase 2
- A Study of Second-line Treatment With Apatinib in Patients With Advanced Intrahepatic CholangiocarcinomaCompletedNCT03251443Phase 2
- Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell CarcinomaTerminatedNCT03251417Phase 2
- Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AMLCompletedNCT03250338Phase 3
- Absorption, Metabolism, Excretion and Absolute BioavailabilityCompletedNCT03250039Phase 1
- A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Neovascular (Wet) Age-related Macular DegenerationCompletedNCT03249740Phase 1
- Sorafenib, Busulfan and Fludarabine in Treating Patients With Recurrent or Refractory Acute Myeloid Leukemia Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03247088Phase 1/2
- A Study of DBPR112 in Patients With Head and Neck Cancer and EGFR Mutated Lung CancerTerminatedNCT03246854Phase 1
- A Study of BMS-986195 in Healthy Male SubjectsCompletedNCT03245515Phase 1
- A Study To Test The Effect Of Apatinib On P450 EnzymesStatus unknownNCT03245307Phase 1
- Phase I Study of the Combination of Apatinib and POFStatus unknownNCT03244774Phase 1
- Low-dose Apatinib Combined With Neoadjuvant Chemotherapy in the Treatment of Early Triple Negative Breast CancerCompletedNCT03243838Phase 2
- Tolerability, Safety, Pharmacokinetics and Efficacy of HS-10241 Single Agent or Combined With Apatinib in Patients With Advanced Solid TumorsStatus unknownNCT03243643Phase 1
- The Efficacy and Safety of Induction-Maintenance Protocol for Patients With Chronic Myelogenous LeukaemiaStatus unknownNCT03241199Phase 2
- Impact of Changing the Dosing Regimen on the PK Profile of ODM-203CompletedNCT03240445Phase 1
- Study of Oral cMET Inhibitor INC280 in Chinese Patients With EGFR Wild-type Advanced Non-small Cell Lung Cancer (NSCLC)WithdrawnNCT03240393Phase 2
- Efficacy and Safety of Precision Therapy in Refractory TumorStatus unknownNCT03239015Phase 2
- Safety and Pharmacokinetic Study of PF-06700841 in Japanese Healthy VolunteersCompletedNCT03236493Phase 1
- A Safety and Tolerability Study of Pemigatinib in Japanese Subjects With Advanced Malignancies - (FIGHT-102)CompletedNCT03235570Phase 1
- Safety and Pharmacokinetic Study of PF-06651600 in Japanese Healthy VolunteersCompletedNCT03232905Phase 1
- Ibrutinib Plus Rituximab and Lenalidomide in Treating Elderly Participants With Newly Diagnosed Mantle Cell LymphomaWithdrawnNCT03232307Phase 2
- HMPL-813 in Treating Patients With GlioblastomaStatus unknownNCT03231501Phase 1
- Varlitinib Plus Capecitabine in Chinese Patients With Advanced or Metastatic Biliary Tract CancerCompletedNCT03231176Phase 2
- Extended Treatment Protocol for Subjects Continuing to Benefit From Ibrutinib.Active, not recruitingNCT03229200Phase 4
- Apatinib Plus XELOX as Neoadjuvant Therapy in Locally Advanced Gastric CancerStatus unknownNCT03229096Phase 2
- Nilotinib Versus Imatinib in Treatment of Patients With Newly Diagnosed Chronic Myeloid LeukemiaStatus unknownNCT03228303Early Phase 1
- Olmutinib Trial in T790M (+) NSCLC Patients Detected by Liquid Biopsy Using BALF Extracellular Vesicular DNACompletedNCT03228277Phase 2
- Apatinib for Resectable Colorectal CancerWithdrawnNCT03228043Not applicable
- Evaluation of Trastuzumab in Combination With Lapatinib or Pertuzumab in Combination With Trastuzumab-Emtansine to Treat Patients With HER2-positive Metastatic Colorectal CancerStatus unknownNCT03225937Phase 2
- Study of Entospletinib (ENTO) in Newly Diagnosed DLBCL Patients With aaIPI>=1 Treated by ChemiotherapyTerminatedNCT03225924Phase 1/2
- Apatinib Combined With Chemotherapy for Esophageal Squamous Cell Cancer After the Failure of Standard TreatmentStatus unknownNCT03224221Phase 2
- A Phase III Study of Fruquintinib in Combination With Paclitaxel in Second Line Gastric Cancer(FRUTIGA)CompletedNCT03223376Phase 3
- Study of Icotinib Hydrochloride Cream in Patients With Mild to Moderate PsoriasisTerminatedNCT03222622Phase 2
- Patient-Derived Xenografts in Personalizing Treatment for Patients With Relapsed/Refractory Mantle Cell LymphomaCompletedNCT03219047Early Phase 1
- Low-dose Dasatinib as First-line Treatment for Chronic Myeloid LeukemiaStatus unknownNCT03216070Phase 4
- X-396 Capsule in Patients With ALK-positive Non-small Cell Lung Cancer Previously Treated With CrizotinibActive, not recruitingNCT03215693Phase 2
- A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat CancerCompletedNCT03215511Phase 1
- Apatinib in Treating Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma (NPC)Status unknownNCT03213587Phase 2
- Clinical Study of Apatinib and 5-Fu Combination Regimen to Treat Advanced Colorectal Cancer PatientsStatus unknownNCT03210064Phase 2
- Study of ASN-002 to Treat Basal Cell Carcinomas (BCCs) in Individuals With Basal Cell Nevus Syndrome (BCNS)SuspendedNCT03208296Phase 1/2
- Phase II Study Testing the Tolerability and the Efficacy of Bosutinib in Chronic Phase CML PatientsStatus unknownNCT03205267Phase 2
- A Phase IB/II Study of Alectinib Combined With Cobimetinib in Advanced ALK-Rearranged (ALK+) NSCLCActive, not recruitingNCT03202940Phase 1/2
- Apatinib Combine With Platinum-Based Doublet Chemotherapy for First-line Treatment of Advanced NSCLCStatus unknownNCT03201146Phase 1/2
- Cabometyx and Avelumab in Patients With Metastatic Renal Cell Carcinoma (mRCC)CompletedNCT03200587Phase 1
- A Clinical Study of Apatinib in Patients With Local Progressive/Metastatic Refractory Thyroid CancerStatus unknownNCT03199677Phase 2
- Study of FF-10101-01 in Patients With Relapsed or Refractory Acute Myeloid LeukemiaCompletedNCT03194685Phase 1
- Study of Crenolanib With Ramucirumab and Paclitaxel for Advanced Esophagogastric AdenocarcinomaCompletedNCT03193918Phase 1
- Safety and Efficacy Study of Chemotherapy Plus Apatinib as Second-line Therapy in Metastatic Colorectal CancerWithdrawnNCT03193814Phase 2
- Apatinib Combined With Docetaxel in the Treatment of Advanced Esophageal Squamous Cell CarcinomaStatus unknownNCT03193424Phase 2
- KISS Study: Kinase Inhibition With Sprycel Start upActive, not recruitingNCT03193281Phase 2
- Apatinib in Refractory Colorectal CancerCompletedNCT03190616Phase 2
- Efficacy and Safety of Maintenance Apatinib Combined With Pemetrexed in Advanced Non-squamous Non-small Cell Lung Cancer PatientsWithdrawnNCT03190239Phase 2
- A Phase I Study of ICP-022 in Healthy SubjectsCompletedNCT03189017Phase 1
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GDC-0853 in Healthy Japanese and Caucasian ParticipantsCompletedNCT03188783Phase 1
- Single-dose Study of [14C]Lorlatinib (PF-06463922) Metabolism In Healthy Male VolunteersCompletedNCT03184168Phase 1
- The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) TrialStatus unknownNCT03182634Phase 2
- Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid TumorsTerminatedNCT03182257Phase 1
- Maintenance Therapy of Apatinib After Chemoradiotherapy in Metastatic Nasopharyngeal CarcinomaCompletedNCT03180476Phase 2
- A Study to Evaluate the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Participants With Non-Small Cell Lung Cancer (NSCLC)Active, not recruitingNCT03178552Phase 2/3
- Daratumumab or FMS Inhibitor JNJ-40346527 Before Surgery in Treating Patients With High-Risk, Resectable Localized or Locally Advanced Prostate CancerCompletedNCT03177460Phase 1
- Telatinib Safety and Pharmacokinetics Study in China Patients With Advanced Solid TumorsCompletedNCT03175497Phase 1
- A Drug-Drug Interaction Study Between GDC-0853 and Midazolam, Itraconazole, Rosuvastatin, and SimvastatinCompletedNCT03174041Phase 1
- The Efficiency of CAMS (Chinese Academy of Medical Sciences)-2016 Trial for Pediatric Acute Myeloid LeukemiaStatus unknownNCT03173612Not applicable
- Study of Nivolumab and Axitinib in Patients With Advanced Renal Cell CarcinomaActive, not recruitingNCT03172754Phase 1/2
- POETIG Trial - POnatinib After rEsisTance to Imatinib in GISTStatus unknownNCT03171389Phase 2
- Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid TumorsActive, not recruitingNCT03170960Phase 1
- Combination of Sorafenib and Omacetaxine Mepesuccinate in Newly Diagnosed or Relapsed/Refractory AML Carrying FLT3-ITDCompletedNCT03170895Phase 2
- Apatinib Treatment for Advanced Esophagus CancerStatus unknownNCT03170310Phase 2
- Exploratory Study of Drug Sensitivity Prediction Software (IRCR-DReSS) With Patient-derived Tumor Cells of Metastatic Gastric CancerCompletedNCT03170180Phase 2
- Phase II Study of Single Agent LenvatinibStatus unknownNCT03168074Phase 2
- Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid CarcinomaStatus unknownNCT03167385Phase 2
- A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia MyelofibrosisActive, not recruitingNCT03165734Phase 3
- APatinib Plus Chemotherapy vErsus Chemotherapy As First-line Treatment for Advanced NSCLCWithdrawnNCT03164694Phase 2
- A Trial of Epigenetic Priming in Patients With Newly Diagnosed Acute Myeloid LeukemiaActive, not recruitingNCT03164057Phase 2
- Apatinib Second Line Treatment for Advanced Osteosarcoma and Soft Tissue Sarcomas ,Openting ,Single Center, One-armed Clinical Study.Status unknownNCT03163381Phase 2
- A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)Active, not recruitingNCT03162536Phase 1/2