Tyrosine Kinase Inhibitors: all 10,479 studies that test it
Page 73 of 105. Open to participants first (1,915), then studies with results posted, then the rest; newest registration first within each.
- Osimertinib In EGFR Mutant Lung CancerActive, not recruitingNCT03586453Phase 2
- CVM-1118 and Sorafenib Combination in Subjects With Advanced Hepatocellular CarcinomaTerminatedNCT03582618Phase 2
- Copanlisib With Ibrutinib for Patients With Recurrent/ Refractory Primary Central Nervous System Lymphoma (PCNSL)CompletedNCT03581942Phase 1/2
- Apatinib in Neoadjuvant Therapy for Patients With Breast CancerStatus unknownNCT03580395Phase 2/3
- Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube CancerActive, not recruitingNCT03579316Phase 2
- SECOX as Neoadjuvant Therapy in Patients With Locally Advanced HCCCompletedNCT03578874Phase 2
- Single-Center Study Evaluating Systemic Exposure and Safety of KX2-391 Ointment 1% on the Face or Balding Scalp in Subjects With Actinic KeratosisCompletedNCT03575780Phase 1
- Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity StudyCompletedNCT03575598Early Phase 1
- Phase II Umbrella Study Directed by Next Generation SequencingStatus unknownNCT03574402Phase 2
- A Study to Evaluate the Safety and Efficacy of Lenvatinib in Participants With Refractory Differentiated Thyroid CancerCompletedNCT03573960Phase 4
- Persistence of MR3 in Chronic Myeloid Leukemia (CML) After a 2nd Stop of TKI TreatmentStatus unknownNCT03573596Phase 2
- A Combination of Acalabrutinib With R-CHOP for Patient Diffuse Large B-cell Lymphoma (DLBCL)CompletedNCT03571308Phase 1/2
- Does Cediranib With Paclitaxel, or Cediranib and Olaparib, Treat Advanced Endometrial Cancer Better Than Paclitaxel?Status unknownNCT03570437Phase 2
- A Study of the Combination of Osimertinib, Platinum and Etoposide for Patients With Metastatic EGFR Mutant Lung CancersActive, not recruitingNCT03567642Phase 1
- Nexavar for Neoadjuvant Treatment of Anaplastic Thyroid CancerCompletedNCT03565536Phase 2
- Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC).CompletedNCT03564938Phase 4
- Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALLStatus unknownNCT03564470Phase 2/3
- Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML)CompletedNCT03564288Phase 1
- Continuation of Nintedanib After Single Lung Transplantation in IPF SubjectsTerminatedNCT03562416Phase 2
- Dasatinib Combined With Chemotherapy in Relapsed t(8;21) Acute Myeloid Leukemia With KIT D816 MutationWithdrawnNCT03560908Phase 1
- The Role of Ruxolitinib in Secondary Acute Myelogenous Leukemia Evolving From Myeloproliferative NeoplasmStatus unknownNCT03558607Phase 1/2
- Masitinib in Combination With FOLFIRI in Third or Fourth Line of Treatment of Patients With Metastatic Colorectal CancerCompletedNCT03556956Phase 2/3
- Clinical Trial to Evaluate the Safety and Effects of Ethnicity and Food on Pharmacokinetics of YH25448CompletedNCT03556436Phase 1
- Food-effect, Drug-Drug Interaction (DDI), and Formulation Bridging StudyCompletedNCT03555617Phase 1
- A Prospective, Single-center, One-arm Clinical Study of Apatinib Combined With Chemotherapy for Pretreated Patients With Advanced Small Cell Lung CancerCompletedNCT03547804Phase 2
- Clinical Study of Apatinib in the Treatment of Advanced Ovarian Cancer After the Failure of Standard ChemotherapyStatus unknownNCT03547375Phase 2
- A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD)-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid CancersCompletedNCT03547037Phase 1
- Apatinib Treating Patients With Advanced Cervical Cancer After Radiotherapy and First-line Chemotherapy.Status unknownNCT03546855Phase 2
- Safety and Efficacy of Anlotinib in Combination With Irinotecan in Patients With Pretreated Advanced Colorectal CancerStatus unknownNCT03545711Phase 1/2
- Apatinib as First -Line Treatment for Advanced Esophagus CancerStatus unknownNCT03542422Phase 2
- Cabozantinib or Sunitinib Malate in Treating Participants With Metastatic Variant Histology Renal Cell CarcinomaActive, not recruitingNCT03541902Phase 2
- An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram EffectsCompletedNCT03541564Phase 1
- Radiotherapy Concurrent With Apatinib in Advanced Soft Tissue and Bone Sarcomas of Head and Neck--RASS StudyStatus unknownNCT03539172Phase 2
- Bioequivalency Study of Ensartinib Capsules in Healthy VolunteersCompletedNCT03536481Phase 1
- Apatinib Combined With Oral Etoposide in Metastatic HER2 Negative Breast CancerCompletedNCT03535961Phase 2
- Osimertinib With Stereotactic Radiosurgery (SRS) in Brain Metastases From EGFR Positive NSCLCCompletedNCT03535363Phase 1
- Phase III Study of Nazartinib (EGF816) Versus Erlotinib/Gefitinib in First-line Locally Advanced / Metastatic NSCLC With EGFR Activating MutationsWithdrawnNCT03529084Phase 3
- Study of Anlotinib in Patients With Primary Malignant Bone TumorsStatus unknownNCT03527888Phase 2
- Ibrutinib and Nivolumab in Treating Participants With Metastatic Solid TumorsCompletedNCT03525925Phase 1
- A Study of Second-line Treatment With Apatinib for Advanced Intrahepatic CholangiocarcinomaStatus unknownNCT03521219Phase 2
- Phase 1 Study of the Combination of Rogaratinib With Copanlisib in Patients With Fibroblast Growth Factor Receptor (FGFR)-Positive, Locally Advanced or Metastatic Solid TumorsCompletedNCT03517956Phase 1
- Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual DiseaseActive, not recruitingNCT03516279Phase 2
- EGF816 and Trametinib in Patients With Non-small Cell Lung Cancer Harboring Activating EGFR MutationsCompletedNCT03516214Phase 1
- A Phase 2 Study of Brivanib in Chinese Patients With Previously Treated Advanced HCCCompletedNCT03516071Phase 2
- Venetoclax and Ibrutinib in Treating in Participants With Chronic Lymphocytic Leukemia and Ibrutinib Resistance MutationsActive, not recruitingNCT03513562Phase 2
- Nintedanib and Azacitidine in Treating Participants With HOX Gene Overexpression Relapsed or Refractory Acute Myeloid LeukemiaActive, not recruitingNCT03513484Phase 1
- The Study of The Treatment of Postoperative Adjuvant Apatinib vs. TACE in Hepatocellular Carcinoma PatientsStatus unknownNCT03511703Phase 2
- Efficacy and Safety of Apatinib Combined With TACE in Patients With Hepatocellular CarcinomaStatus unknownNCT03510416Phase 2
- Pharmacokinetic and Safety Study of MRX-2843 in Adults With Relapsed/Refractory Advanced and/or Metastatic Solid TumorsCompletedNCT03510104Phase 1
- A Study of Oral Lorlatinib in Patients With Relapsed ALK Positive LymphomaCompletedNCT03505554Phase 2
- Risk of Tuberculous and Other Infections in Patients of Spondyloarthritis Treated With Tofacitinib in BangladeshStatus unknownNCT03504072Phase 4
- Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of ASK120067 in Locally Advanced and Metastatic Non Small Cell Lung CancerStatus unknownNCT03502850Phase 1/2
- Study of Trametinib + Ceritinib in Patients With Unresectable MelanomaCompletedNCT03501368Phase 1
- Phase 1b of ASLAN001 (Varlitinib) in Patients With Advanced/ Metastatic Hepatocellular Carcinoma (HCC)Status unknownNCT03499626Phase 1/2
- Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese SubjectsCompletedNCT03497273Phase 1
- A Study to Evaluate ICP-022 in Patients With R/R Mantle Cell Lymphoma (MCL)CompletedNCT03494179Phase 1/2
- A Study to Evaluate ICP-022 in Patients With CLL/ SLLStatus unknownNCT03493217Phase 1/2
- Phase I Study of SHR9146 + SHR-1210 +/- Apatinib in Patients With Advanced Solid TumorsStatus unknownNCT03491631Phase 1
- Afatinib Plus Chemotherapy Against Esophageal or Lung Squamous Cell CarcinomaStatus unknownNCT03486509Phase 2
- Gefitinib and Berberine in the First-line Treatment of Lung Adenocarcinoma With EGFR MutationStatus unknownNCT03486496Phase 2
- Rogaratinib (BAY1163877) Human Mass Balance StudyCompletedNCT03484585Phase 1
- Phase I Study of HMPL-523+Azacitidine in Elderly Patients With Acute Myeloid LeukemiaTerminatedNCT03483948Phase 1
- Safety, Tolerability and Efficacy of Vaginal Suppositories for Treatment of the EndometriosisWithdrawnNCT03481842Phase 1/2
- Study of PAN-90806 Eye Drops, Suspension for Neovascular AMDCompletedNCT03479372Phase 1/2
- Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin LymphomaActive, not recruitingNCT03479268Phase 1
- Phase II Palbociclib +Ibrutinib in Mantle Cell LymphomaActive, not recruitingNCT03478514Phase 2
- Study on the Adverse Drug Reactions (ADRs) of Apatinib and Their Biomarker CorrelationsStatus unknownNCT03475589Phase 4
- A Study to Try to Bring Back Radioiodine Sensitivity in Patients With Advanced Thyroid Cancer.TerminatedNCT03469011Phase 1
- Study to Evaluate the Safety and Anti-tumor Activity of SCC244CompletedNCT03466268Phase 1
- Safety and Pharmacokinetics of Zanubrutinib (BGB-3111) in Healthy Subjects and Those With Impaired Liver FunctionCompletedNCT03465059Phase 1
- A Study of CaBozantinib in Patients With Advanced or Unresectable Renal cEll cArcinomaCompletedNCT03463681Phase 2
- Pembrolizumab and Sunitinib Malate in Treating Participants With Refractory Metastatic or Unresectable Thymic CancerActive, not recruitingNCT03463460Phase 2
- Randomized Comparative Study of Erlotinib and Pemetrexed in the Maintenance Treatment of Advanced Lung Cancer Patients.TerminatedNCT03460678Phase 4
- Osimertinib as First-line Therapy for Patients With Late-stage Lung CancerStatus unknownNCT03460275Phase 2
- A Study of Anlotinib in Patients With Gastroenteropancreatic Neuroendocrine Tumor G3Status unknownNCT03457844Phase 2
- A Phase I Study of SCC244 in Patients with Advanced MET Alterations Solid TumorsCompletedNCT03457532Phase 1
- Clinical Study of Apatinib Combined With SBRT Therapy in the Treatment of Oligometastasis of Breast CancerStatus unknownNCT03457467Phase 2
- S-1 Plus Gefitinib Versus Gefitinib Monotherapy in Patients With EGFR-sensitive Mutation Advanced Non-squamous NSCLCStatus unknownNCT03457337Phase 2
- A Study of BNC105P Combined With IbrutinibCompletedNCT03454165Phase 1
- Efficacy and Safety of Alflutinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer Patients With T790MTerminatedNCT03452592Phase 2
- D-0316 First Time in Patients Ascending Dose StudyCompletedNCT03452150Phase 1
- Assessing an Oral Janus Kinase Inhibitor, AZD4205, in Combination With Osimertinib in Patients Who Have Advanced Non-small Cell Lung CancerCompletedNCT03450330Phase 1/2
- Trial of Sunitinib in Patients With Type B3 Thymoma or Thymic Carcinoma in Second and Further Lines (Style Trial)Status unknownNCT03449173Phase 2
- Daratumumab and Ibrutinib in Treating Patients With Symptomatic Chronic Lymphocytic LeukemiaCompletedNCT03447808Phase 1
- A Study of ZN-e4 in Subjects With Epidermal Growth Factor Receptor Mutated Non-Small Cell Lung CancerCompletedNCT03446417Phase 1
- To Evaluate the Safety, Tolerability and Pharmacokinetics of K0706 in Plasma and Cerebrospinal Fluid in Healthy VolunteersCompletedNCT03445338Phase 1
- Extended Access of Momelotinib in Adults With MyelofibrosisActive, not recruitingNCT03441113Phase 2
- Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell LymphomaCompletedNCT03440567Phase 1
- PF-06463922 for Crizotinib Pretreated ROS1 Positive Non-small-cell Lung CancerStatus unknownNCT03439215Phase 2
- Prior Axitinib as a Determinant of Outcome of Renal SurgeryActive, not recruitingNCT03438708Phase 2
- Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK)CompletedNCT03436394Phase 1
- A Two-Part Phase 1 Study to Investigate the Safety and Tolerability of Supratherapeutic Dose of Zanubrutinib and Effect of Zanubrutinib on Cardiac Repolarization in Healthy SubjectsCompletedNCT03432884Phase 1
- A Study of Poziotinib in Combination With T-DM1 in HER2-Positive Breast CancerTerminatedNCT03429101Phase 1
- Apatinib for Advanced Biliary CarcinomaStatus unknownNCT03427242Phase 2
- Niraparib in Combination with Cabozantinib (XL184) in Patients with Advanced Urothelial Cancer (NICARAGUA)CompletedNCT03425201Phase 1/2
- Uncommon EGFR AZD9291Status unknownNCT03424759Phase 2
- A Study to Evaluate the Food-Effect of H3B-6527CompletedNCT03424577Phase 1
- A Retrospective Clinical Study of Apatinib in Combination With Radiotherapy / Chemotherapy Second-line and Above in the Treatment of Recurrent / Metastatic Head and Neck Squamous Cell CarcinomaStatus unknownNCT03424291Phase 2
- INCB050465 in Combination With Rituximab, Bendamustine and Rituximab, or Ibrutinib in Participants With Previously Treated B-Cell Lymphoma (CITADEL-112)CompletedNCT03424122Phase 1
- Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic DermatitisCompletedNCT03422822Phase 3