Taurolidine clinical trials
Includes 1 study of Taurolidine citrate.
How each study uses taurolidine is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- 15 Nov 2023 · DEFENCATH · NDA 214520 (FDA, Drugs@FDA; in a combination)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
8 studies that test it; most in 2001 (2)
| Year | Studies |
|---|---|
| 2001 | 2 |
| 2006 | 1 |
| 2012 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2019 | 1 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 2 · Other 6
Geistlich Pharma AG (2) · Memorial Sloan Kettering Cancer Center (2) · Oman Ministry of Health (1) · Stanley Dudrick's Memorial Hospital (1) · Radboud University Medical Center (1) · Hospital de Clinicas de Porto Alegre (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses taurolidine is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 8
- Antimicrobial Locks for Hemodialysis Catheter InfectionsCompletedPhase 2Oman Ministry of HealthNCT07074821Written as Taurolidine citrate 4% and heparin 500
- Trial to Evaluate Safety, Tolerability, Efficacy of PerioSept® as Adjunct to SRP in Subjects With PeriodontitisCompletedPhase 2Geistlich Pharma AGNCT04093895Written as PerioSept(r)
- A Phase I/II Study to Evaluate the Safety and Efficacy of PerioSept® as Adjunct to SRP in Subjects With PeriodontitisCompletedPhase 1/2Geistlich Pharma AGNCT02313883Written as PerioSept(r)
- Heparin Versus Taurolidine to Bloodstream Infection Prevention Related in Central Venous Catheter in ChildrenStatus unknownPhase 4Hospital de Clinicas de Porto AlegreNCT02515201Written as Taurolidine
- Taurolidine Lock in Long Term Parenteral NutritionCompletedPhase 4Stanley Dudrick's Memorial HospitalNCT02009189Written as 1.35% Taurolidine
- Taurolidine in Treating Patients With Recurrent or Progressive GliomaCompletedPhase 1Memorial Sloan Kettering Cancer CenterNCT00022360Written as taurolidine
- Taurolidine in Treating Patients With Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal CancerCompletedPhase 1Memorial Sloan Kettering Cancer CenterNCT00021034Written as taurolidine
- The AOT (Acridine Orange and Taurolidine) TrialCompletedPhase 3Radboud University Medical CenterNCT00321165Written as taurolidine
Codes
What other systems call taurolidine · ClinicalTrials.gg INT002553
- MeSH (NLM) C012566taurolidineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 8OBZ1M4V3VTAUROLIDINEConfirmed FDA, NLM, Wikidata
- Wikidata Q3981568taurolidineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C2639TaurolidineOne source FDA
- DrugBank DB12473One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C012566 | taurolidine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 8OBZ1M4V3V | TAUROLIDINE | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q3981568 | taurolidine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C2639 | Taurolidine | One source FDA |
| DrugBank | DB12473 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.