Thiazide diuretics: all 264 studies that test it

Page 2 of 3. Open to participants first (26), then studies with results posted, then the rest; newest registration first within each.

• Non-interaction Study of Chlorthalidone and Losartan in Fixed Combination, in Healthy Subjects, Under Fasting ConditionsCompletedNCT05090449Phase 1
• A Bioequivalence Study Between Capozide Versus ACE-Hemmer-ratiopharm in Healthy Adult Participants Under Fasting ConditionsWithdrawnNCT04964050Phase 1
• DAPAgliflozin Versus Thiazide Diuretic in Patients With Heart Failure and Diuretic RESISTanceStatus unknownNCT04860011Phase 3
• Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.CompletedNCT04757532Phase 1
• Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure ReductionActive, not recruitingNCT04676399Early Phase 1
• Study to Evaluate the Influence of Hydrochlorothiazide on Dermal Photosensitivity and DNA Stability - a Pilot Study (HCTox Study)CompletedNCT04654312Phase 1
• The Standardized Management of Hypertension in Rural ShaanxiCompletedNCT04371874Not applicable
• Phthalates Exposure in Type 2 Diabetic Patients and Diuretic TherapyStatus unknownNCT04242758Phase 4
• Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping ControlCompletedNCT04197622Phase 1
• Sequential Nephron Blockade in Acute Heart FailureStatus unknownNCT04163588Phase 3
• Efficacy of Chlorthalidone and Hydrochlorothiazide Combined With Amiloride on Blood Pressure in Primary Hypertension.Status unknownNCT03928145Phase 3
• Reversal of an Unfavorable Effect of Hydrochlorothiazide Compared to Angiotensin Converting Enzyme Inhibitor on Serum Uric Acid and Oxypurines Levels by Estrogen-progestin Therapy in Hypertensive Postmenopausal Women.CompletedNCT03921736Phase 4
• Protocol of Diuretics Use in Congestive Therapy in Heart FailureCompletedNCT03892148Phase 4
• A Study to Evaluate the Drug-drug Interaction Between Telmisartan, Amlodipine and HydrochlorothiazideCompletedNCT03889145Phase 1
• Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill PatientsStatus unknownNCT03658850Phase 2
• Fixed-Free HTN TrialStatus unknownNCT03578042Phase 4
• Prospective Comparison of Metolazone Versus Chlorothiazide for Acute Decompensated Heart Failure With Diuretic ResistanceTerminatedNCT03574857Phase 4
• Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two DrugsCompletedNCT03560804Not applicable
• Dapagliflozin Effect on Erythropoiesis and Physical FitnessWithdrawnNCT03423355Phase 4
• A Drug to Drug Interaction Study of Sotagliflozin With HydrochlorothiazideCompletedNCT03387657Phase 1
• A Study on Molecular Genetics of Drug Responsiveness in Essential HypertensionCompletedNCT03276598Phase 4
• Empagliflozin and Sympathetic Nerve TrafficCompletedNCT03254849Phase 4
• Pharmacogenomics of Hypertension Personalized Medicine (PGX-HT)Status unknownNCT03249285Phase 3
• The Effect of Diuretics on Mineral and Bone Disorder in Chronic Kidney Disease PatientsStatus unknownNCT03082742Not applicable
• Effect of Antihypertensive Agents on Diastolic Function in Patients With Sleep ApneaCompletedNCT02896621Phase 3
• DD-study: Diet or Diuretics for Salt-sensitivity in Chronic Kidney DiseaseCompletedNCT02875886Phase 4
• The Precision Hypertension Care StudyCompletedNCT02774460Phase 4
• N-of-1 Trials for Blood Pressure Medications in AdultsCompletedNCT02744456Early Phase 1
• Comparison of Three Combination Therapies in Lowering Blood Pressure in Black AfricansCompletedNCT02742467Phase 4
• Efficacy and Safety of TAH Combination in Comparison With Telmisartan/Amlodipine Combination for Essential Hypertension PatientsCompletedNCT02738632Phase 3
• Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine CalciumCompletedNCT02711670Not applicable
• Once-daily Fixed Combination of Three Antihypertensive DrugsStatus unknownNCT02710539Phase 4
• Benidipine and Hydrochlorothiazide in Fosinopril Treated Chronic Kidney Disease Patients With HypertensionStatus unknownNCT02646397Phase 4
• Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using TacrolimusCompletedNCT02644395Phase 3
• Diagnosing and Targeting Mechanisms of Diuretic Resistance in Heart FailureCompletedNCT02546583Phase 1
• Efficacy and Safety of Candesartan Associated With Chlorthalidone Versus Losartan Associated With Hydrochlorothiazide (Hyzaar®) in Essential Hypertension ControlWithdrawnNCT02521246Phase 3
• Efficacy and Safety of Candesartan Associated With Chlorthalidone in Essential Arterial Hypertension ControlWithdrawnNCT02521233Phase 3
• Comparing the Effects of Spironolactone With Chlortalidone on LV Mass in Patients With CKDStatus unknownNCT02502981Phase 4
• Efficacy and Safety of Fimasartan Alone or Combined With HCTZ in Mexican Patients With Essential HypertensionCompletedNCT02466490Phase 3
• Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic EdemaCompletedNCT02427880Phase 4
• Lowering Blood Pressure in Primary Care in ViennaCompletedNCT02377661Phase 4
• Mechanisms of Refractory Hypertension (Carvedilol)WithdrawnNCT02357004Not applicable
• Comparison of Single and Combination Diuretics in Low-Renin HypertensionStatus unknownNCT02351973Phase 4
• Bioequivalence of Telmisartan as Telmisartan 80 mg/HCTZ 12.5 mg Fixed-dose Combination Tablet or as Two Telmisartan 40 mg Tablets in Healthy Male VolunteersCompletedNCT02276391Phase 1
• Bioequivalence of Telmisartan/ HCTZ Fixed Dose Combination Compared With Its Monocomponents in Healthy Male Volunteers IICompletedNCT02262858Phase 1
• Telmisartan and Hydrochlorothiazide Antihypertensive Treatment Study in High Sodium Intake PopulationCompletedNCT02255253Not applicable
• A Clinical Trial to Evaluate Efficacy, Tolerability, and Pharmacokinetic-Pharmacodynamic Relationship of Fimasartan/HydrochlorothiazideCompletedNCT02222480Phase 2
• Treatment of Hypertension in Tibetan Adult PopulationStatus unknownNCT02217852Phase 4
• Treatment of HYpertension: Morning Versus EveningStatus unknownNCT02214498Phase 4
• Relative Oral Bioavailability of Telmisartan / Hydrochlorothiazide (HCTZ) Fixed Dose Combination (FDC) Compared With Its Monocomponents in Healthy SubjectsCompletedNCT02187523Phase 1
• Telmisartan Plus Hydrochlorothiazide in Subjects With Mild-to-moderate Hypertension Who Failed to Respond to Telmisartan MonotherapyCompletedNCT02177500Phase 3
• Safety Evaluation of Telmisartan Plus Hydrochlorothiazide in Patients With Mild-to-Moderate HypertensionCompletedNCT02177487Phase 3
• Telmisartan With or Without Hydrochlorothiazide in Patients With Mild-to-moderate HypertensionCompletedNCT02177435Phase 3
• Efficacy and Safety of Chronic Administration of Telmisartan as Monotherapy or in Combination With Hydrochlorothiazide or Other Antihypertensive Medications in Patients With Mild to Moderate HypertensionCompletedNCT02177422Phase 3
• Telmisartan/Hydrochlorothiazide (HCTZ) Fixed Dose Combination Compared to Its Monocomponents in Healthy SubjectsCompletedNCT02176512Phase 1
• Telmisartan With or Without Hydrochlorothiazide (HCTZ) Compared With Losartan With or Without HCTZ in Mild to Moderate Hypertensive PatientsCompletedNCT02172586Phase 4
• Drug-drug Interaction Study (Telmisartan, Amlodipine, Chlorthalidone)CompletedNCT02152969Phase 1
• Chlorthalidone and HCTZ Impacts on Platelet ActivationStatus unknownNCT02100462Phase 4
• A Prospective, Single-center, Randomized, Controlled, Open-label, Pilot Study to Compare the Effectiveness and Safety of DIuretics Add-On Strategy in Acute Decompensated Heart Failure Patients (DIOS II)WithdrawnNCT02047422Not applicable
• The Management of Resistant Hypertension in Kidney Transplant Patients Using ChlorthalidoneWithdrawnNCT02030314Phase 4
• Non-invasive Haemodynamic Assessment in HypertensionCompletedNCT01996085Not applicable
• Clinical Trial to Compare Effectiveness of Diuretics in Hemodialysis Patients With Residual Renal FunctionStatus unknownNCT01977430Phase 4
• Pharmacokinetic Interactions of Losartan and HydrochlorothiazideCompletedNCT01858623Not applicable
• Drug Interaction Between Irbesartan and HydrochlorothiazideCompletedNCT01858610Not applicable
• Efficacy/Safety Study of Valsartan and Chlorthalidone Conjugate Treatment Compared to Simple Treatment for HypertensionCompletedNCT01850160Phase 3
• Chlorthalidone Compared to Hydrochlorothiazide on Endothelial FunctionWithdrawnNCT01822860Phase 4
• Randomized, Open Labeled Clinical Trial to Compare the Effectiveness of Amlodipine/Valsartan vs Hydrochlorothiazide/Telmisartan on Glucose Tolerance in Patients With Hypertension With Metabolic SyndromeCompletedNCT01819220Phase 4
• A Prospective, Single-center, Open-label, Pilot Study to Compare the Effectiveness and Safety of Diuretics Add-On Strategy in Chronic Heart Failure Patients (DIOS 1)WithdrawnNCT01817803Not applicable
• Pharmacokinetic Interactions and Safety Study of Telmisartan and ChlorthalidoneCompletedNCT01806363Phase 1
• Pharmacokinetic Interactions of Valsartan and Hydrochlorothiazide (Double Doses)CompletedNCT01767298Not applicable
• Pharmacokinetic Interactions of Valsartan and HydrochlorothiazideCompletedNCT01767259Not applicable
• EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative NetworkWithdrawnNCT01748123Phase 4
• Crossover Bioequivalence Study of Irbesartan HCTZ 300/25 mg Tablets Under Fasted ConditionsCompletedNCT01712139Not applicable
• Crossover Bioequivalence Study of Irbesartan Hydrochlorothiazide 300/25 mg Tablets Under Fed ConditionsCompletedNCT01712126Not applicable
• Clinical Assessment Of Association Pharmacokinetics Atorvastatin + Losartana + HydrochlorothiazideCompletedNCT01692717Phase 1
• Safety and Efficacy of the Combination of Loop With Thiazide-type Diuretics in Patients With Decompensated Heart FailureCompletedNCT01647932Phase 3
• Comparison of Losartan Associated With Indapamide Versus Hyzaar® in the Hypertension TreatmentSuspendedNCT01620788Phase 3
• Aliskiren vs Hydrochlorothiazide in Hypertensive Type II Diabetic Patients on Resistance ArteriesWithdrawnNCT01480791Phase 2
• Combination of Nebivolol and Valsartan Given as Free Tablets for Stage 1 or Stage 2 HypertensionCompletedNCT01415505Phase 3
• Changes in Endothelial Function and Biomarkers in African Americans (AA) With Metabolic SyndromeStatus unknownNCT01271374Phase 4
• Hypertensive Ambulatory Trial to Compare the Efficacy of HCTZ and LisinoprilCompletedNCT01258764Not applicable
• Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fed ConditionsCompletedNCT01218724Phase 1
• Bioequivalence Study of Losartan Potassium and Hydrochlorothiazide (100 mg / 25 mg Tablet) [Test Formulation, Torrent Pharmaceuticals Ltd., India] Versus Hyzaar® (100 mg / 25 mg Tablet) [Reference Formulation, Merck & Co., Inc., USA] in Healthy Human Volunteers Under Fasting Conditions.CompletedNCT01218711Phase 1
• Recurrent Stroke Prevention Clinical Outcome StudyStatus unknownNCT01198496Phase 4
• Telmisartan, Amlodipine and Flow Mediated DilationStatus unknownNCT01180205Phase 4
• Indapamide Versus Hydrochlorothiazide in Elderly Hypertensive Patients With Renal InsufficiencyCompletedNCT01172431Phase 4
• Treatment of Adiposity Related hypErTension (TARGET)CompletedNCT01138423Phase 4
• Aliskiren in Combination With Amlodipine in Hypertensive Patients Not Responding to Angiotensin Receptor Blocker (ARB) Plus AmlodipineCompletedNCT01113047Phase 3
• Bioequivalency Study of Losartan Potassium/Hydrochlorothiazide 100 mg/25 mg Tablet Under Fasted ConditionsCompletedNCT01102478Not applicable
• Efficacy and Safety of Combination Therapy of Aliskiren/Amlodipine or Aliskiren/Amlodipine/Hydrochlorothiazide in Patients With Stage II HypertensionCompletedNCT01070030Phase 4
• A Clinical Study With Aliskiren Alone or in Combination Therapy With Diuretic Hctz in Venezuelan Hypertensive Patients.CompletedNCT01056731Phase 4
• Efficacy and Safety of Candesartan Cilexetil Plus Hydrochlorothiazide in Subjects With Severe HypertensionCompletedNCT01012479Phase 4
• Study to Determine the Effects of Nebivolol and Hydrochlorothiazide in African Americans With HypertensionCompletedNCT00999752Not applicable
• Monotherapy Versus Dual Therapy for Initial Treatment for HypertensionStatus unknownNCT00994617Phase 4
• A Comparison of Indapamide SR 1.5 mg With HCTZ 25 mg, in Combination With an ACE-inhibitor, in Patients With Mild to Moderate AHT and Type 2 DMCompletedNCT00980187Phase 4
• Hypertension Prevention in Pre-Hypertensive IndividualsCompletedNCT00970931Phase 3
• A Study to Evaluate the Safety and Pharmacokinetics After Oral Concurrent Administration of Fimasartan and Hydrochlorothiazide in Healthy Male VolunteersCompletedNCT00923533Phase 1
• Evaluation of the Additional Efficacy, and Safety of Olmesartan Medoxomil 20mg / Hydrochlorothiazide 12.5mg in the Treatment of Chinese Patients With Mild to Moderate Essential HypertensionCompletedNCT00872586Phase 3
• Renin Profiling in Selection of Initial Antihypertensive DrugCompletedNCT00834600Not applicable
• Reducing the Overall Risk Level in Patients Suffering From Metabolic SyndromeCompletedNCT00821574Phase 4

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