Reverse Transcriptase Inhibitors: all 1,328 studies that test it

Page 4 of 14. Open to participants first (42), then studies with results posted, then the rest; newest registration first within each.

• Optimizing Pediatric HIV-1 Treatment in Infants With Prophylactic Exposure to Nevirapine, Nairobi, KenyaTerminatedNCT00427297Phase 3Results posted
• Safety and Effectiveness of Short-Term Anti-HIV Drug Therapy for Recent HIV-1 InfectionCompletedNCT00414518Not applicableResults posted
• Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant VirusCompletedNCT00410202Phase 3Results posted
• Entecavir Plus Tenofovir Combination Therapy Versus Entecavir Monotherapy in Naive Subjects With Chronic Hepatitis BCompletedNCT00410072Phase 3Results posted
• Study of Adefovir Dipivoxil for Korean Patients With Chronic Hepatitis B(CHB) Who Have Completed ADF 103814CompletedNCT00403585Phase 4Results posted
• Safety, Tolerability and Pharmacokinetics of Efavirenz in HIV-Infected ChildrenCompletedNCT00364793Phase 1/2Results posted
• An Open-label Trial With TMC125 in Patients Who Have Virologically Failed in a DUET Trial (TMC125-C206 or TMC125-C216).CompletedNCT00359021Phase 3Results posted
• Safety and Efficacy of Tenofovir DF in HIV-1 Infected Adolescents Failing Their Current Antiretroviral TherapyCompletedNCT00352053Phase 3Results posted
• Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive ParticipantsCompletedNCT00350272Phase 2Results posted
• Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or CirrhosisCompletedNCT00347009Phase 4Results posted
• Antiretroviral Therapy for Advanced HIV Disease in South AfricaCompletedNCT00342355Phase 4Results posted
• ALTAIR - Alternative Antiretroviral Strategies : a Comparison of Three Initial RegimensCompletedNCT00335322Phase 4Results posted
• Pharmacokinetics of Atazanavir/Ritonavir in HIV-1 Infected Pregnant WomenCompletedNCT00326716Phase 1Results posted
• Adefovir Dipivoxil Tablets (10mg) In Chinese Subjects With HBe Antigen Negative Chronic Hepatitis BCompletedNCT00324961Phase 4Results posted
• Peripheral Body Fat Distribution After Switching Zidovudine and Lamivudine to TruvadaCompletedNCT00324649Phase 4Results posted
• TOTEM: Switch From Other Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to Once Daily TruvadaCompletedNCT00323492Phase 4Results posted
• Adefovir Dipivoxil In Compensated Chronic Hepatitis B PatientsCompletedNCT00316719Phase 3Results posted
• Treatment of Persistent Viremia (Virus in Blood) in Chronic Hepatitis B Subjects Already Receiving Adefovir DipivoxilCompletedNCT00307489Phase 2Results posted
• Antiviral Responses to NNRTI-Based vs. PI-Based ARV Therapy in HIV Infected Infants Who Have or Have Not Received Single Dose NVP for Prevention of Mother-to-Child Transmission of HIVCompletedNCT00307151Phase 2Results posted
• Study Comparing Tenofovir Disoproxil Fumarate (TDF), Emtricitabine (FTC)/TDF, and Entecavir (ETV) in the Treatment of Chronic HBV in Subjects With Decompensated Liver Disease.CompletedNCT00298363Phase 2Results posted
• Trizivir Vs. Kaletra and Combivir for the Prevention of Mother-to-Child Transmission of HIVCompletedNCT00270296Phase 2Results posted
• Viral Dynamics and Pharmacokinetics of Abacavir and TenofovirCompletedNCT00214890Phase 2Results posted
• Pharmacokinetics of Efavirenz in HIV-1 Infected Subjects With Hepatic ImpairmentCompletedNCT00162097Phase 1Results posted
• Extended Safety Study of Tenofovir Disoproxil Fumarate (TDF) Among HIV-1 Negative MenCompletedNCT00131677Phase 2Results posted
• A Study With TMC125 in Human Immunodeficiency Virus (HIV) Type 1 Infected Patients, Who Were Treated With TMC125 Arm in a Sponsor-Selected TMC125 StudyCompletedNCT00128830Phase 2Results posted
• Bangkok Tenofovir Study, an HIV Pre-exposure Prophylaxis Trial, Bangkok, ThailandCompletedNCT00119106Phase 2/3Results posted
• Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive AdultsCompletedNCT00118898Phase 3Results posted
• Tenofovir Disoproxil Fumarate/Emtricitabine/Efavirenz Versus Combivir/Efavirenz in Antiretroviral-Naive HIV-1 Infected SubjectsCompletedNCT00112047Phase 3Results posted
• A Study of TMC278 in Human Immunodeficiency Virus Type 1 Infected Patients, Who Are Not Treated With Antiretroviral MedicinesCompletedNCT00110305Phase 2Results posted
• Anti-HIV Drugs for Treating Infants Who Acquired HIV Infection at BirthCompletedNCT00102960Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of an Investigational Drug in HIV Infected Patients (0518-004)(COMPLETED)CompletedNCT00100048Phase 2Results posted
• Comparison of Three Anti-HIV Regimens to Prevent Nevirapine Resistance in Women Who Take Nevirapine During PregnancyCompletedNCT00099632Phase 2Results posted
• Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV TransmissionCompletedNCT00099359Phase 3Results posted
• Trial of Maraviroc (UK-427,857) in Combination With Zidovudine/Lamivudine Versus Efavirenz in Combination With Zidovudine/LamivudineCompletedNCT00098293Phase 3Results posted
• Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B InfectionCompletedNCT00096785Phase 3Results posted
• Safety and Efficacy of Adefovir Dipivoxil in Children and Adolescents With Chronic Hepatitis BCompletedNCT00095121Phase 3Results posted
• Nine Month Course of Anti-HIV Medications for People Recently Infected With HIVTerminatedNCT00090779Phase 2Results posted
• NNRTI vs PI Regimens for HIV Infected Women After They Have Taken Nevirapine to Prevent Mother-To-Child HIV TransmissionCompletedNCT00089505Phase 3Results posted
• Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited SettingsCompletedNCT00084136Phase 4Results posted
• Preventing Sexual Transmission of HIV With Anti-HIV DrugsCompletedNCT00074581Phase 3Results posted
• Using Nevirapine to Prevent Mother-to-Child HIV Transmission During BreastfeedingCompletedNCT00074412Phase 3Results posted
• Atazanavir (BMS-232632) in Combination With Ritonavir or Saquinavir, and Lopinavir/Ritonavir, Each With Tenofovir and a Nucleoside in Subjects With HIVCompletedNCT00035932Phase 3Results posted
• Lamivudine and Adefovir to Treat Chronic Hepatitis BCompletedNCT00023309Phase 2Results posted
• Safety and Effectiveness of Emtricitabine, Efavirenz, and Didanosine in HIV Infected Children Who Have Taken Few or No Anti-HIV DrugsCompletedNCT00016718Phase 1/2Results posted
• Studies of the Ocular Complications of AIDS (SOCA)--Foscarnet-Ganciclovir CMV Retinitis Trial (FGCRT)CompletedNCT00000136Phase 3Results posted
• Studies of the Ocular Complications of AIDS (SOCA)--Cytomegalovirus Retinitis Retreatment Trial (CRRT)CompletedNCT00000134Phase 3Results posted
• A Clinical Trial of MK-4646 With Bictegravir/Emtricitabine/Tenofovir Alafenamide and Dolutegravir in Healthy Adult Participants (MK-4646)CompletedNCT07532304Phase 1
• A Clinical Study of Ulonivirine (MK-8507) With Atorvastatin and Metformin in Healthy Adults (MK-8507-018)CompletedNCT07530289Phase 1
• A Study of [14C]Ulonivirine ([14C]MK-8507) in Healthy Adults (MK-8507-006)CompletedNCT07334886Phase 1
• A Clinical Trial to Evaluate the Effect of Ulonivirine (MK-8507) on Heart Rhythm in Healthy Adults (MK-8507-012)CompletedNCT07305831Phase 1
• Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore StudyActive, not recruitingNCT07210528Phase 1
• A Study of Doravirine/Islatravir in Healthy Lactating Females (MK-8591A-061)CompletedNCT07086079Phase 1
• A Study of Exercise and Pharmacologic Intervention on Systemic InflammationActive, not recruitingNCT07058974Phase 1
• Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIVActive, not recruitingNCT07055451Phase 1
• Utilizing Private Pharmacies to Initiate High-risk Young Individuals on PrEP in South AfricaActive, not recruitingNCT07006246Phase 4
• A Clinical Study of the Interactions Between Azvudine Tablets (FNC) and Rilpivirine Tablets (RPV)CompletedNCT07001488Phase 1
• A Study of Islatravir (ISL) and Ulonivirine (ULO) Once Weekly (QW) in Virologically Suppressed Adults With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8591B-060)Active, not recruitingNCT06891066Phase 2
• A Study of Emtricitabine/Tenofovir Disoproxil Fumarate (FTC/TDF) and MK-8527 in Healthy ParticipantsCompletedNCT06816043Phase 1
• A Clinical Study of Islatravir and Its Interaction With Lamivudine (MK-8591-058)CompletedNCT06811246Phase 1
• Clinical Trial of Gammora® Plus Antiretroviral Treatment for HIVActive, not recruitingNCT06799650Phase 2
• A Study of the Effect Efavirenz on the Plasma Levels of MK-7602 in Healthy Participants (MK-7602-005)CompletedNCT06797674Phase 1
• A Study of Doravirine and Islatravir as a Single Entity or Combination Therapy and the Effect of Food in Healthy Adult Participants (MK-8591A-055)CompletedNCT06719570Phase 1
• A Study of the Effect of Efavirenz on the Plasma Levels of Nemtabrutinib (MK-1026-014)CompletedNCT06698016Phase 1
• Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1Active, not recruitingNCT06630286Phase 3
• A Study of MK-8507 and Islatravir (MK-8591) in Healthy Adult Participants (MK-8507-016)CompletedNCT06619678Phase 1
• A Single-center, Self-controlled, Prospective Case Series Pilot Study to Assess the Effect of Lamivudine (3TC) on Neurocognitive Impairment Biomarkers and Type-I IFN (Interferon)-Stimulated Genes in the Plasma of Patients With Mild Cognitive Impairment (MCI)Active, not recruitingNCT06519357Phase 2
• Study of Lenacapavir Taken Twice a Year for HIV Pre-Exposure Prophylaxis (PrEP)Active, not recruitingNCT06513312Phase 2
• Lamivudine for Solid TumorsActive, not recruitingNCT06494579Phase 1/2
• B/F/TAF to DTG/3TC Switch StudyActive, not recruitingNCT06444620Phase 3
• Optimizing PrEP Regimens for Pregnant Women in Sub-Saharan Africa (O-PrEP Study) - Stage 1CompletedNCT06435026Phase 2
• Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With BiktarvyActive, not recruitingNCT06333808Phase 3
• TGRX-326 Pharmacokinetic Drug InteractionCompletedNCT06294561Phase 1
• Study of Bictegravir/Emtricitavine/Tenofovir Alafenamide in HIV-1 Infected naïve Patients Using Test and Treat Stategy Rapid-initiation Model of Care: BIC-NOW Clinical Trial (BIC-NOW)CompletedNCT06177574Phase 4
• To Evaluate the Safety and Pharmacokinetic Characteristics After the Administration of JC-001 and JLP-1901CompletedNCT06171880Phase 1
• Acceptability and Feasibility of Injectable Cabotegravir Pre-exposure Prophylaxis (PrEP) Versus Oral PrEP in Routine Care up to 15 Months in Private Pharmacies in South AfricaActive, not recruitingNCT06138600Phase 3
• Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) for Prevention of HIV in People Who Inject Drugs (HPTN 103)Active, not recruitingNCT06101342Phase 2
• Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)Active, not recruitingNCT06101329Phase 2
• Lamivudine and Plasma Markers of Inflammation in Retinal DetachmentTerminatedNCT06056596Early Phase 1
• UNIVERSAL 1: Pharmacokinetic Study of a Novel DTG/FTC/TAF Dose Ratio for ChildrenCompletedNCT05993767Phase 2
• A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral TherapyActive, not recruitingNCT05979311Phase 3
• A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral TherapyCompletedNCT05917509Phase 3
• A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)Active, not recruitingNCT05766501Phase 3
• The COMBAT HBV Feasibility TrialCompletedNCT05705427Phase 4
• DOR/ISL in HIV-1 Antiretroviral Treatment-naïve Participants (MK-8591A-053)Active, not recruitingNCT05705349Phase 3
• A Trial of DDI Between SHR1459 and Efavirenz With Healthy SubjectsCompletedNCT05560360Phase 1
• Telehealth as a Modality to Increase the Uptake of PrEP Services in Black and Latino: "e-PrEP"CompletedNCT05528653Phase 4
• Project Engage: Oral PrEP AcceptabilityCompletedNCT05458765Phase 2
• Doravirine and Weight Gain in Antiretroviral NaiveWithdrawnNCT05457530Phase 3
• Efficacy of Tenofovir Disoproxil on Mother-to-child Transmission of HBV in Tokombéré, Cameroon in Pregnant WomenActive, not recruitingNCT05403047Phase 4
• Efficacy and Safety of Ricovir® in Maintaining Durability of Viral Response in Chronic Hepatitis B Patients Who Have Been Treated With Viread® and Have Undetectable HBV DNA in SerumCompletedNCT05355467Phase 4
• Drug-drug Interaction Study of Ganaplacide and Lumefantrine With EfavirenzCompletedNCT05330273Phase 1
• Dolutegravir-Lamivudine as Dual Therapy in naïve HIV-Infected Patients With Documented M184V Mutation:A Pilot StudyWithdrawnNCT05295394Phase 4
• Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis BCompletedNCT05286346Phase 4
• A phase4 Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis BCompletedNCT05282407Phase 4
• Triumeq in Amyotrophic Lateral SclerosisTerminatedNCT05193994Phase 3
• Study to Assess Switching to B/F/TAF in Treatment Experienced People With HIV Who Are at Least 65 Years of AgeStatus unknownNCT05147740Phase 4
• A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy SubjectsCompletedNCT05137548Phase 1
• A Study of Islatravir (MK-8591) in Trans and Gender Diverse Participants (MK-8591-035)WithdrawnNCT05130086Phase 2
• Switching From TDF-based Antiretroviral Therapy Regimens to B/F/TAF in Virally Suppressed Adults With HIV-1 InfectionActive, not recruitingNCT05122754Phase 4
• Radiopaque Matrix MK-8591 Implant in Participants at Low-Risk for Human Immunodeficiency Virus Type 1 (HIV-1) Infection (MK-8591-043)WithdrawnNCT05115838Phase 2

← Reverse Transcriptase Inhibitors overview