Reverse Transcriptase Inhibitors: all 1,328 studies that test it

Page 3 of 14. Open to participants first (42), then studies with results posted, then the rest; newest registration first within each.

• Evaluating the Safety and Tolerability of Etravirine in HIV-1 Infected Infants and ChildrenCompletedNCT01504841Phase 1/2Results posted
• Safety and Efficacy of E/C/F/TAF (Genvoya®) Versus E/C/F/TDF (Stribild®) in HIV-1 Infected, Antiretroviral Treatment-Naive AdultsCompletedNCT01497899Phase 2Results posted
• Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B Untreated With Nucleic Acid AnalogueCompletedNCT01480284Phase 3Results posted
• Phase 3 Study of GSK548470 in Patients With Compensated Chronic Hepatitis B With Poor Response to Other DrugsCompletedNCT01475851Phase 3Results posted
• A Key Link for Transmission PreventionCompletedNCT01450189Not applicableResults posted
• Effect of Tenofovir on Genital Herpes Simplex Virus (HSV) SheddingCompletedNCT01448616Phase 4Results posted
• Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative VolunteersCompletedNCT01427504Not applicableResults posted
• Bone, Immunologic, and Virologic Effects of a Antiretroviral RegimenCompletedNCT01400412Phase 2Results posted
• Trial to Assess the Impact of PrEP to Tenofovir Gel on the Efficacy of Tenofovir-containing ART on Viral SuppressionCompletedNCT01387022Not applicableResults posted
• Effect of Gender and HIV Infection on Zidovudine and Lamivudine PharmacokineticsCompletedNCT01386970Phase 4Results posted
• Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis BCompletedNCT01369212Phase 3Results posted
• Lactic Acidosis During Entecavir(ETV)TreatmentTerminatedNCT01354652Phase 4Results posted
• Study of Options for Second-Line Effective Combination Therapy (SELECT)CompletedNCT01352715Phase 3Results posted
• Antiretroviral Therapy (ART) Alone or With Delayed Chemo Versus ART With Immediate Chemo for Limited AIDS-related Kaposi's SarcomaCompletedNCT01352117Phase 3Results posted
• Drug Drug Interaction of BI 201335 and TenofovirCompletedNCT01340196Phase 1Results posted
• Evaluation of 3TC or FTC Mono-therapy Compared to Continuing HAART as a Bridging StrategyTerminatedNCT01338025Phase 4Results posted
• Study to Evaluate the Safety and Efficacy of a Single Tablet Regimen of Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate Compared With a Single Tablet Regimen of Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate in HIV-1 Infected, Antiretroviral Treatment-Naive AdultsCompletedNCT01309243Phase 3Results posted
• Efficacy and Safety of Tenofovir Disoproxil Fumarate (TDF) 300mg in Chinese Subjects With Chronic Hepatitis B (CHB)CompletedNCT01300234Phase 3Results posted
• Study to Evaluate Switching From a Regimen Consisting of the Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate Single-Tablet Regimen (STR) to the Emtricitabine/Rilpivirine/Tenofovir Disoproxil Fumarate STRCompletedNCT01286740Phase 2Results posted
• Comparative Safety Study of Two Vaginal Applicators With TenofovirCompletedNCT01283555Not applicableResults posted
• Efficacy & Safety of Tenofovir Disoproxil Fumarate (TDF) Plus Peginterferon α-2a (Peg-IFN) Versus TDF or Peg-IFN Monotherapy in Chronic Hepatitis BCompletedNCT01277601Phase 4Results posted
• Effects of Switching Efavirenz to Raltegravir on Vascular Function and Bone Markers in HIV-infected PatientsCompletedNCT01270802Phase 4Results posted
• A Trial With TMC278-TIDP6-C222 for Continued TMC278 Access in Patients Infected With Human Immunodeficiency Virus-1CompletedNCT01266902Phase 3Results posted
• Post-Exposure Prophylaxis in Health Care WorkersCompletedNCT01234116Phase 4Results posted
• Effects of Famotidine on the Pharmacokinetics of Atazanavir When Coadministered to Participants With HIV InfectionCompletedNCT01232127Phase 4Results posted
• Truvada Plus Raltegravir for Nonoccupational Post-exposure Prophylaxis (nPEP)CompletedNCT01214759Phase 4Results posted
• A Study of the Once Daily Combination of Etravirine and Darunavir/Ritonavir As Dual Therapy in Early Treatment-Experienced PatientsCompletedNCT01199939Phase 2Results posted
• Atripla to Raltegravir Switch Study for CNS ToxicityCompletedNCT01195467Phase 3Results posted
• Treatment Options for Protease Inhibitor-exposed ChildrenCompletedNCT01146873Phase 3Results posted
• Adefovir Plus Vaccination in Transplant Patients Without Hepatitis B That Receive a Core Antibody Positive LiverCompletedNCT01146808Phase 1/2Results posted
• Biobehavioral Interventions for HIV-negative, Stimulant Using Men Who Have Sex With MenCompletedNCT01140880Phase 2Results posted
• A Study of Pegylated Interferon Alfa-2a and Lamivudine in Patients With HBeAg-Negative Chronic Hepatitis B Virus (HBV)CompletedNCT01095835Phase 3Results posted
• Cryptococcal Optimal ART Timing TrialCompletedNCT01075152Phase 4Results posted
• Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous TreatmentCompletedNCT01063036Phase 3Results posted
• Evaluating Strategies to Reduce Mother-to-Child Transmission of HIV Infection in Resource-Limited CountriesCompletedNCT01061151Phase 3Results posted
• Drug Interaction Study With Ribavirin and Abacavir in Male Subjects With Hepatitis C Who Have Failed Ribavirin TreatmentCompletedNCT01052701Phase 1Results posted
• Triomune Bioequivalence With InnovatorsCompletedNCT01025830Phase 4Results posted
• HIV Persistence and Viral ReservoirsCompletedNCT01025427Phase 4Results posted
• Safety and Efficacy of Reduced Versus Standard Dose Efavirenz (EFV) Plus Two Nucleotides in Antiretroviral-naïve Adults.CompletedNCT01011413Phase 3Results posted
• Artery Elasticity After Switch From Epzicom to TruvadaTerminatedNCT00998582Phase 4Results posted
• TMC125-TiDP35-C239 - Continued Access to Etravirine (ETR) in Treatment Experienced HIV-1 Infected ParticipantsCompletedNCT00980538Phase 3Results posted
• HIV Protease Inhibitors for the Prevention of Malaria in Ugandan ChildrenCompletedNCT00978068Phase 3Results posted
• Efavirenz as Second-Line Therapy in Treating Patients With Metastatic Pancreatic CancerCompletedNCT00964171Phase 2Results posted
• Efavirenz in Treating Patients With Metastatic Prostate CancerCompletedNCT00964002Phase 2Results posted
• A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or BothCompletedNCT00962871Phase 1Results posted
• Switch From Combivir or Trizivir to Truvada - Mitochondrial EffectsCompletedNCT00960622Phase 4Results posted
• Evaluating Once Daily Etravirine in Treatment-Naive Adults With HIV InfectionCompletedNCT00959894Phase 2Results posted
• Interventions for HIV Negative Men and Women Who Have High-risk Suspected Exposure to HIVCompletedNCT00949234Phase 2Results posted
• Rollover Protocol Continued Access to Emtricitabine/Tenofovir Disoproxil Fumarate for Adults in United StatesCompletedNCT00936715Phase 2Results posted
• Evaluation of Three Strategies of Second-line Antiretroviral Treatment in Africa (Dakar - Bobo-Dioulasso - Yaoundé)CompletedNCT00928187Phase 3Results posted
• Treatment of Acute HIV With Emtricitabine, Tenofovir and Efavirenz (CID 0805)CompletedNCT00924898Phase 4Results posted
• A Study of PEGASYS (Peginterferon Alfa-2a (40KD)) in Combination With Adefovir or Entecavir in Patients With HBeAg-Positive Chronic Hepatitis BCompletedNCT00922207Phase 4Results posted
• A Phase I Multiple Dose Pharmacokinetic Study of Nevirapine Extended Release (XR) in HIV-1 Infected Children.CompletedNCT00905489Phase 1Results posted
• A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected PatientsCompletedNCT00903682Phase 2Results posted
• Immune Reconstitution as a Determinant of Adverse Effects to New Antiretroviral Therapy in Persons With Advanced HIV InfectionCompletedNCT00885664Phase 4Results posted
• Effects of Etravirine on Endothelial Function in HIV-uninfected Adults: A Pilot StudyCompletedNCT00871234Phase 1Results posted
• A Pilot Project of Virologic, Pharmacologic and Immunologic Correlates of Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution Following Maraviroc TherapyCompletedNCT00870363Phase 4Results posted
• Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in Healthy WomenCompletedNCT00869960Phase 4Results posted
• Contingency Management for Methamphetamine Abstinence and HIV Post-Exposure Prophylaxis in Men Who Have Sex With MenCompletedNCT00856323Phase 2Results posted
• HIV Viremia and Persistence in Acutely HIV-Infected Patients Treated With Darunavir/Ritonavir and EtravirineTerminatedNCT00855413Phase 4Results posted
• A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir and Ritonavir, Darunavir and Cobicistat, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant WomenCompletedNCT00855335Phase 3Results posted
• Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2CompletedNCT00810303Phase 1Results posted
• A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 YearsCompletedNCT00799864Phase 2Results posted
• Immune Reconstitution of Lopinavir/Ritonavir-Based vs Efavirenz-based HAART in Advanced HIV DiseaseTerminatedNCT00775606Phase 4Results posted
• Raltegravir vs. Atazanavir in Combination With Truvada® for the Treatment of Antiretroviral naïve HIV Infected PatientsCompletedNCT00762892Phase 4Results posted
• Rollover Study Protocol for Pediatric Patients in South Africa for Continued Access to EmtricitabineCompletedNCT00743340Phase 2Results posted
• Tenofovir Disoproxil Fumarate (Tenofovir DF) Versus Emtricitabine/Tenofovir DF in Subjects Resistant to LamivudineCompletedNCT00737568Phase 3Results posted
• A Study to Evaluate Tenofovir Disoproxil Fumarate (DF) in Asian-American Adults With Chronic Hepatitis B InfectionCompletedNCT00736190Phase 4Results posted
• Pilot Study of Raltegravir/Truvada Versus Efavirenz/Truvada for Adults With Acute IV-1 InfectionCompletedNCT00734344Not applicableResults posted
• Evaluation of Tenofovir Disoproxil Fumarate in Adolescents With Chronic Hepatitis B InfectionCompletedNCT00734162Phase 3Results posted
• A Study in Underrepresented Patient Population or Regimen Tolerability: SUPPoRTCompletedNCT00727597Phase 3Results posted
• Safety and Efficacy Study of Switching From Epzicom to TruvadaCompletedNCT00724711Phase 4Results posted
• Safety and Effectiveness of TFV 1% Gel, TDF Tablets, and FTC/TDF Tablets in Preventing HIV in WomenCompletedNCT00705679Phase 2Results posted
• TMC125-TiDP35-C213: Safety and Antiviral Activity of Etravirine (TMC125) in Treatment-Experienced, HIV Infected Children and AdolescentsCompletedNCT00665847Phase 2Results posted
• Pilot Project of Virologic and Immunologic Correlates of GALT Immune Reconstitution Following Raltegravir TherapyCompletedNCT00661960Not applicableResults posted
• Raltegravir + Lopinavir/Ritonavir or Emtricitabine/Tenofovir for HIV Treatment Naive SubjectsCompletedNCT00654147Phase 2Results posted
• The Effect of Raltegravir on HIV Decay During Primary and Chronic InfectionCompletedNCT00641641Not applicableResults posted
• FEM-PrEP (Truvada®): Study to Assess the Role of Truvada® in Preventing HIV Acquisition in WomenCompletedNCT00625404Phase 3Results posted
• Clinical Trial of CNS-targeted HAART (CIT2)CompletedNCT00624195Phase 2/3Results posted
• Determining the Effects of Observed and Self-Administered Drug Regimens in HIV Infected AdultsCompletedNCT00608569Not applicableResults posted
• A Phase IIIb Study to Compare Entecavir Plus Tenofovir vs. Adefovir Added to Continuing Lamivudine Therapy in Adult Patients With Lamivudine-Resistant Hepatitis B InfectionTerminatedNCT00605384Phase 3Results posted
• HIV Non Occupational Post-Exposure Prophylaxis (PEP)CompletedNCT00594646Phase 4Results posted
• Adherence and Acceptability to and Blood Levels of Tenofovir Gel and Tablets in HIV Uninfected WomenCompletedNCT00592124Phase 2Results posted
• VERxVE Study on Efficacy and Safety of Nevirapine XR in Comparison to Nevirapine IR With Truvada in Naive HIV+ PatientsCompletedNCT00561925Phase 3Results posted
• Pre-Exposure Prophylaxis to Prevent HIV-1 Acquisition Within HIV-1 Discordant CouplesCompletedNCT00557245Phase 3Results posted
• Nevirapine vs. Atazanavir Boosted With Ritonavir on a Background of Truvada in Human Immunodeficiency Virus (HIV) Infected Naive Patients (NEwArT)CompletedNCT00552240Phase 4Results posted
• KIVEXA Vs TRUVADA, Both Administered With Efavirenz, In ART-Naive SubjectsCompletedNCT00549198Phase 4Results posted
• TMC278-TiDP6-C215: A Clinical Trial in Treatment Naive HIV-subjects Patients Comparing TMC278 to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase InhibitorsCompletedNCT00543725Phase 3Results posted
• TMC278-TiDP6-C209: A Clinical Trial in Treatment Naive HIV-1 Patients Comparing TMC278 to Efavirenz in Combination With Tenofovir + Emtricitabine.CompletedNCT00540449Phase 3Results posted
• Optimizing Treatment for Treatment-Experienced, HIV-Infected PeopleCompletedNCT00537394Phase 3Results posted
• A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).CompletedNCT00534352Phase 2Results posted
• Safety and Efficacy of Switching From Stavudine or Zidovudine to Tenofovir DF in HIV-1 Infected ChildrenCompletedNCT00528957Phase 3Results posted
• Tenofovir Alone Versus Tenofovir With Emtricitabine to Treat Chronic Hepatitis BTerminatedNCT00524173Phase 2Results posted
• Enfuvirtide/Current Protease Inhibitor Switch to PREZISTA (Darunavir)/Ritonavir + TMC125 in HIV Patients With Enfuvirtide Side Effects.CompletedNCT00460746Phase 3Results posted
• Emtricitabine/Tenofovir Disoproxil Fumarate for HIV Prevention in MenCompletedNCT00458393Phase 3Results posted
• Mechanisms of Lipodystrophy in HIV-Infected PateintsCompletedNCT00457665Phase 4Results posted
• Botswana TDF/FTC Oral HIV Prophylaxis TrialCompletedNCT00448669Phase 2/3Results posted
• HIV Treatment Reinitiation in Women Who Received Anti-HIV Drugs to Prevent Mother-to-Child Transmission of HIVCompletedNCT00442962Phase 4Results posted
• Adefovir Dipivoxil For The Treatment Of Chinese Compensated Chronic Hepatitis B(CHB)PatientsCompletedNCT00441974Phase 4Results posted
• Induction/Simplification With Atazanavir + Ritonavir + Abacavir/Lamivudine Fixed-Dose Combination In HIV-1 InfectionCompletedNCT00440947Phase 3Results posted

← Reverse Transcriptase Inhibitors overview