P2Y12 inhibitors: all 610 studies that test it
Page 4 of 7. Open to participants first (61), then studies with results posted, then the rest; newest registration first within each.
- Impact of Antiretroviral Treatment on Pharmacokinetics and Pharmacodynamics of Thienopyridines in Healthy Volunteers and HIV PatientsTerminatedNCT03054207Phase 1
- Platelet Aggregation in Patients With Coronary Artery Disease and Kidney Dysfunction Taking Clopidogrel or TicagrelorCompletedNCT03039205Phase 2
- A Single Center Study to Evaluate Ticagrelor Mechanism of Action in Inhibiting Juvenile Platelet ADP ResponseWithdrawnNCT03027934Phase 4
- Different Dosage of Domestic and Imported Clopidogrel on the Platelet Inhibition Ratio in Patients Undergoing PCIStatus unknownNCT03006835Phase 4
- Reversal of the Antiplatelet Effects of Ticagrelor in Combination With Aspirin, Using Normal PlateletsStatus unknownNCT03005704Not applicable
- A Trial to Assess the Safety and Efficacy of Prophylactic TicagrelOr With Acetylsalicylic Acid Versus CLopidogrel With Acetylsalicylic Acid in the Development of Cerebrovascular EMbolic Events During TAVICompletedNCT02989558Phase 3
- Randomized Comparison of Cangrelor, Tirofiban and Prasugrel in Patients With STEMI Referred for Primary PCI.CompletedNCT02978040Phase 4
- Half Dose of Prasugrel and Ticagrelor in Acute Coronary Syndrome (HOPE-TAILOR)CompletedNCT02944123Phase 3
- Cangrelor Following Ticagrelor Loading vs Ticagrelor Loading Alone in STEMICompletedNCT02943369Phase 4
- Optimal Duration of Antiplatelet Therapy After Bioresorbable Vascular Scaffold Implantation to Reduce Late Coronary Arterial Thrombotic EventsCompletedNCT02939872Phase 4
- Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With MorphineCompletedNCT02939248Phase 4
- Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With MorphineCompletedNCT02939235Phase 4
- Migraine Prophylaxis With Clopidogrel TrialStatus unknownNCT02938182Phase 4
- Drug-Drug Interaction Study to Assess the Effects of Multi Dose Clopidogrel on the Pharmacokinetics of Single-Dose K-877 in Healthy Adult VolunteersCompletedNCT02922465Phase 1
- Effects of Different Doses of Ticagrelor on Platelet Aggregation and Endothelial Function in Diabetic Patients With Stable Coronary Artery DiseaseStatus unknownNCT02889549Phase 2/3
- Antiplatelet Therapy in Acute Mild-Moderate Ischemic StrokeCompletedNCT02869009Phase 3
- Safety Profile Evaluation of TICagrelor Alone Compared to a Combination of Lysine Acetylsalicylate-Clopidogrel in the Context of Transcatheter Aortic Valve Implantation (TAVI)TerminatedNCT02817789Phase 3
- Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial InfarctionCompletedNCT02808767Phase 4
- Effects of Ticagrelor on No-reflow in Patients With Acute ST-segment Elevation Myocardial InfarctionStatus unknownNCT02798874Not applicable
- Ticagrelor Versus Clopidogrel in Myocardial Salvage in Patients With STEMI Undergoing Primary PCIStatus unknownNCT02792712Phase 4
- Clopidogrel for Acute Ischaemia of Recent OnsetCompletedNCT02776540Phase 4
- The Success of Opening Single CTO Lesions to Improve Myocardial Viability Study (SOS-comedy)CompletedNCT02767401Phase 4
- Cangrelor Neonatal PK/PD and Safety StudyCompletedNCT02765633Phase 1
- Post-operative Treatment of Diabetic Peripheral Arterial Disease Guided by Platelet Reactivity UnitStatus unknownNCT02762864Not applicable
- Platelet Inhibition of Ticagrelor Versus Clopidogrel in Type 2 Diabetic Patients After Elective Percutaneous Coronary InterventionCompletedNCT02748330Phase 4
- COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome TrialsWithdrawnNCT02723981Phase 4
- Genotyping Influences Outcome of Coronary Artery StentingCompletedNCT02707445Not applicable
- High On-treatment Platelet Reactivity Identified by Multiple Platelet Function AssayCompletedNCT02699008Not applicable
- Comparison Between Effect of Enoxaparin and Clopidogrel on Improving Pregnancy Rate in ICSIStatus unknownNCT02696330Phase 4
- Ticagrelor Versus Clopidogrel in Carotid Artery StentingCompletedNCT02677545Phase 2
- Ticagrelor vs Clopidogrel for Platelet Inhibition in Stenting for Cerebral AneurysmCompletedNCT02675205Phase 3
- A Randomized, Pharmacodynamic Comparison of Low Dose Ticagrelor to Clopidogrel in Patients With Prior Myocardial InfarctionCompletedNCT02663713Phase 4
- Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVICompletedNCT02640794Phase 4
- Rapid P2Y12 Receptor Inhibition Attenuates Inflammatory Cell Infiltration in Thrombus Aspirated From the STEMI PatientsCompletedNCT02639143Phase 4
- Patent Versus Generic Clopidogrel in Acute Coronary SyndromeStatus unknownNCT02628587Phase 4
- The Effect of Ticagrelor on 15-Epi-Lipoxin A4 and InflammationWithdrawnNCT02626169Phase 4
- Comparing Ticagrelor Versus Clopidogrel on MicrocirculationCompletedNCT02618733Not applicable
- Assessment of Loading With the P2Y12 Inhibitor Ticagrelor or Clopidogrel to Halt Ischemic Events in Patients Undergoing Elective Coronary StentingCompletedNCT02617290Phase 3
- Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic StudyCompletedNCT02612116Phase 4
- Zainidip in Renal Artery StenosisCompletedNCT02594410Phase 4
- Hunting for the Off-Target Properties of Ticagrelor on Endothelial Function in Humans (HI-TECH)CompletedNCT02587260Phase 4
- The Effect of Ticagrelor or Clopidogrel on Endothelial Function During Acute and Chronic TreatmentCompletedNCT02580149Phase 4
- COmparison of the Pharmacodynamics and Pharmacokinetics Ticagrelor Versus Clopidogrel in Patients With CKD and NSTE-ACSStatus unknownNCT02578537Phase 4
- Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy SubjectsCompletedNCT02560688Phase 1
- ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNtsCompletedNCT02519608Phase 2
- Safety and Efficacy of Low-dose Ticagrelor in Chinese Patients With Stable Coronary Artery DiseaseStatus unknownNCT02514642Phase 4
- Evaluation of Antiplatelet Effects and Safety of Intraoperative Administration of Ticagrelor Versus ClopidogrelStatus unknownNCT02513004Phase 4
- Ticagrelor vs. Prasugrel Effects on Infarct SizeWithdrawnNCT02507323Phase 2
- Platelet Reactivity in Acute Non-disabling Cerebrovascular EventsCompletedNCT02506140Phase 2/3
- TIcagrelor in Rotational Atherectomy to Reduce TROPonin EnhancementCompletedNCT02505399Phase 4
- Ticagrelor Monotherapy After 3 Months in the Patients Treated With New Generation Sirolimus Stent for Acute Coronary Syndrome (TICO Study)Status unknownNCT02494895Phase 4
- Short-Term Dual Antiplatelet and Maintenance CloPidogrel Therapy After Drug-Eluting Stent ImplantationTerminatedNCT02494284Phase 4
- Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Coronary StentingCompletedNCT02487732Phase 4
- Peripheral Endothelial Function Assessment of Patients on Ticagrelor vs. Clopidogrel Who Have Undergone PCICompletedNCT02469740Phase 4
- Comparison of TIcagrelor and Clopidogrel in Patients With Coronary Artery diseaSe and Type 2 Diabetes Mellitus (TICS-DM)Status unknownNCT02457130Phase 4
- Plasma and Platelet microRNAs in Clopidogrel Low Response PatientsStatus unknownNCT02447809Phase 4
- Efficacy and Safety of BiomatrixTM Stent and 5mg-Maintenance Dose of Prasugrel in Patients With Acute Coronary SyndromeStatus unknownNCT02446730Phase 4
- CV004-007 Thrombosis Chamber StudyCompletedNCT02439190Phase 1
- Dose Adaptation to Offset the Interaction Between Ticagrelor and Ritonavir by Population-based PK ModelingCompletedNCT02435563Phase 2
- Short vs Long Duration Dual Antiplatelet Therapy in Patients Undergoing Lower Extremity Endovascular RevascularizationWithdrawnNCT02433587Phase 3
- A Multicenter Trial to Assess the MIcrovascular Integrity and Left Ventricular Function Recovery After Clopidogrel or TicagrelOr Administration, in Patients With STEMI Treated With Thrombolysis - The 'MIRTOS' StudyCompletedNCT02429271Phase 3
- Role of Immune Responses After Acute Myocardial InfarctionStatus unknownNCT02428374Phase 4
- Reducing Micro Vascular Dysfunction in Acute Myocardial Infarction by TicagrelorStatus unknownNCT02422888Phase 4
- Safety and Efficacy of Low-Dose Ticagrelor in Chinese Patients With NSTE-ACSStatus unknownNCT02415803Phase 3
- The Dynamic Effect of Non-cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized and Cytochrome P450 Isoenzyme 3A4（CYP3A4）-Metabolized Statins on Clopidogrel Resistance in Patients With Cerebral InfarctionStatus unknownNCT02411903Phase 4
- Ticagrelor and Peripheral Arterial DiseaseTerminatedNCT02407314Phase 4
- Ticagrelor and Anti-inflammatory EffectsStatus unknownNCT02406911Phase 3
- Safety and Efficacy of Clopidogrel in Locally Advanced and Metastatic Pancreatic Adenocarcinoma Treated With ChemotherapyTerminatedNCT02404363Phase 3
- Genotype and Platelet Reactivity in Patients on HemodialysisStatus unknownNCT02394145Phase 3
- Reversal of the Anti-platelet Effects of TicagrelorCompletedNCT02383771Phase 4
- Effect of Ticagrelor Versus Clopidogrel on Endothelial Dysfunction and Vascular InflammationStatus unknownNCT02379676Phase 4
- The Effect Of Ticagrelor On Saphenous Vein Graft Patency In Patients Undergoing Coronary Artery Bypass Grafting SurgeryStatus unknownNCT02352402Phase 3
- Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary SyndromeCompletedNCT02341729Phase 4
- Prevention of Venous Obstruction After Implantation of Cardiac Pacemaker and DefibrillatorStatus unknownNCT02331511Not applicable
- A Single-center, Prospective,Randomized Study of Antiplatelet Effects of Ticagrelor Versus Clopidogrel in Patients With Dual Anti-platelet Therapy After Coronary Artery Bypass GraftingCompletedNCT02330640Phase 4
- Comparison of Low-Dose, Standard-Dose Ticagrelor and Clopidogrel for Inhibition of Platelet Reactivity in Patients With Acute Coronary SyndromesCompletedNCT02319941Phase 2
- Ticagrelor or Prasugrel Versus Clopidogrel in Elderly Patients With an Acute Coronary Syndrome and a High Bleeding Risk: Optimization of Antiplatelet Treatment in High-risk ElderlyCompletedNCT02317198Phase 4
- Pharmacokinetics of Antiplatelet Drugs in Diabetic pAtientsWithdrawnNCT02302508Phase 4
- Ticagrelor in Patients With ST Elevation Myocardial Infarction Treated With Pharmacological ThrombolysisCompletedNCT02298088Phase 3
- High "on Treatment" Platelet Reactivity in the Intensive Care UnitStatus unknownNCT02285751Phase 2
- Effect of Ticagrelor on Adenosine-Induced Coronary Flow Reserve in Patients With Microvascular AnginaStatus unknownNCT02284048Phase 4
- Influence of Clopidogrel on the Pharmacodynamics and Safety of Fradafiban in Healthy Male SubjectsCompletedNCT02265289Phase 1
- Relative Bioavailability of Telmisartan and SR26334 After Co-administration Compared to the Bioavailability of Telmisartan and SR26334 After Administration of Telmisartan and Clopidogrel Alone in Healthy Male and Female SubjectsCompletedNCT02262650Phase 1
- Ticagrelor and Endothelial FunctionStatus unknownNCT02261922Phase 4
- Antiplatelet Therapy for Patients Undergoing Transcatheter Aortic Valve ImplantationCompletedNCT02247128Phase 4
- Ticagrelor and Clopidogrel on Reperfusion in Patients With AMIStatus unknownNCT02233790Phase 4
- Ticagrelor Versus Clopidogrel in Left Ventricular Remodeling After ST-segment Elevation Myocardial InfarctionStatus unknownNCT02224534Phase 4
- Study of Antiplatelet Therapy for Intracranial Aneurysm Stent-assisted CoilingStatus unknownNCT02224131Phase 4
- Platelet Reactivity After TAVI: A Multicenter Pilot StudyCompletedNCT02224066Phase 4
- Influence of Clopidogrel on the Pharmacodynamics and Safety of Terbogrel in Healthy Male SubjectsCompletedNCT02222987Phase 1
- Arachidonic Acid-induced Platelet Aggregation Rate in Patients With Stable CAD Treated With Ticagrelor MonotherapyCompletedNCT02219412Phase 4
- Sampling P2Y12 Receptor Inhibition With Prasugrel and Ticagrelor in Patients Submitted to ThrombolysisCompletedNCT02215993Phase 4
- TIcaGrEloR and ABSORB Bioresorbable Vascular Scaffold Implantation for Recovery of Vascular Function After Successful Chronic Total Occlusion RecanalizationCompletedNCT02211066Phase 4
- Safety of "Ticagrelor+ Warfarin"in Comparison With "Clopidogrel+Aspirin+Warfarin"CompletedNCT02206815Phase 4
- Efficacy of Ticagrelor vs Clopidogrel in High-risk NSTE-ACS Patients Undergoing Early PCIStatus unknownNCT02201667Phase 4
- Investigation of the Impact of Concomitant Use of Multiple Doses of Clopidogrel With Multiple Doses of Dabigatran Etexilate on the Pharmacokinetic and Pharmacodynamic Parameters in Healthy Male SubjectsCompletedNCT02171598Phase 1
- Is Efficacy of PLAtelet Aggregation Inhibition by Ticagrelor Mediated P2Y12 Blockade Dependent Upon Endogenous Endothelial Nitric OXide?CompletedNCT02169596Phase 4
- ONSET and OFFSET of Ticagrelor in ESRDCompletedNCT02163954Phase 3
- Optical Coherence Tomography to Evaluate Ticagrelor and ClopidogrelCompletedNCT02140801Phase 4
- Comparison of Ticagrelor And Clopidogrel on Inflammatory Biomarkers And Vascular Endothelial FunctionStatus unknownNCT02123004Phase 4