P2Y12 inhibitors: all 610 studies that test it

Page 2 of 7. Open to participants first (61), then studies with results posted, then the rest; newest registration first within each.

• Comparative Efficacy of Ticagrelor Versus Aspirin on Blood Viscosity in Peripheral Artery Disease Patients With Type 2 DiabetesCompletedNCT02325466Phase 3Results posted
• A Study to Compare the Safety of Rivaroxaban Versus Acetylsalicylic Acid in Addition to Either Clopidogrel or Ticagrelor Therapy in Participants With Acute Coronary SyndromeCompletedNCT02293395Phase 2Results posted
• Study of Ticagrelor Versus Aspirin Treatment in Patients With Myocardial Injury Post Major Non-cardiac SurgeryTerminatedNCT02291419Phase 4Results posted
• Switching From Ticagrelor to Clopidogrel in Patients With Coronary Artery DiseaseCompletedNCT02287909Phase 4Results posted
• NIRS Ticagrelor EvaluationCompletedNCT02282332Phase 4Results posted
• Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb IschemiaTerminatedNCT02230527Phase 2/3Results posted
• Walking Effect of Long Term Ticagrelor in Subjects With PAD Who Have Undergone EVRTerminatedNCT02227368Phase 2Results posted
• Antiplatelet Therapy After Cardiac ArrestCompletedNCT02224274Phase 4Results posted
• Antiplatelet Strategy for Peripheral Arterial Interventions for Revascularization of Lower ExtremitiesCompletedNCT02217501Phase 3Results posted
• Different Antiplatelet Therapy Strategy After Coronary Artery Bypass Graft SurgeryCompletedNCT02201771Phase 4Results posted
• Reversing Ticagrelor's Effects With Fresh PlateletsCompletedNCT02201394Phase 4Results posted
• Clopidogrel Bioequivalence Study in Healthy SubjectsCompletedNCT02185534Phase 1Results posted
• Switch to Ticagrelor in Critical Limb Ischemia Anti-platelet StudyCompletedNCT02091921Phase 1/2Results posted
• In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated PatientsCompletedNCT02081443Not applicableResults posted
• Prasugrel and Ticagrelor in ST-segment Elevation Myocardial InfarctionTerminatedNCT02075125Phase 3Results posted
• A Pharmacodynamic Study Comparing Prasugrel Versus Ticagrelor in Patients Undergoing PCI With CYP2C19 Loss-of-function:CompletedNCT02065479Phase 4Results posted
• Ticagrelor China Pharmacokinetic/Pharmacodynamic StudyCompletedNCT02064985Phase 4Results posted
• Ticagrelor Antiplatelet Therapy to Reduce Graft Events and ThrombosisCompletedNCT02053909Phase 4Results posted
• Ticagrelor vs Clopidogrel in Non-ST Elevation Acute Coronary Syndrome Patients Undergoing PCI With Bivalirudin.TerminatedNCT02052635Phase 4Results posted
• Pharmacokinetics, Pharmacodynamics, and Safety Study of Ticagrelor in Hemodialysis Patients and Healthy SubjectsCompletedNCT02022748Phase 1Results posted
• Pharmacodynamic Evaluation of Switching From Prasugrel to TicagrelorCompletedNCT02016170Not applicableResults posted
• Ticagrelor in Severe Community Acquired PneumoniaTerminatedNCT01998399Phase 2Results posted
• [SOCRATES -Acute Stroke Or Transient IsChaemic Attack TReated With Aspirin or Ticagrelor and Patient OutcomES]CompletedNCT01994720Phase 3Results posted
• A Study Comparing Cardiovascular Effects of Ticagrelor Versus Placebo in Patients With Type 2 Diabetes MellitusCompletedNCT01991795Phase 3Results posted
• Different LD of Ticagrelor for Antiplatelet Effect in Patients With Non-ST-segment Elevation ACS Undergoing PCICompletedNCT01962428Phase 4Results posted
• Does Continued Use of Clopidogrel Into Surgery Cause Increased Perioperative Bleeding?CompletedNCT01960296Phase 2Results posted
• Ticagrelor and Eptifibatide Bolus-Only Versus Ticagrelor and Eptifibatide Bolus Plus Abbreviated InfusionCompletedNCT01919723Phase 2Results posted
• High Ticagrelor Loading Dose in STEMICompletedNCT01898442Phase 2Results posted
• Ranitidin Versus Omeprazole in Patients Taking ClopidogrelCompletedNCT01896557Phase 4Results posted
• Brilinta DaYu StudyCompletedNCT01870921Phase 4Results posted
• A Phase IV Study of the Onset and Maintenance of the Antiplatelet Effect of Ticagrelor Compared With Clopidogrel in Chinese Patients With ACSCompletedNCT01864005Phase 4Results posted
• Pharmacodynamic Effect of Prasugrel vs. Ticagrelor in DiabetesCompletedNCT01852214Not applicableResults posted
• Pharmacodynamic Effects of Prasugrel Compared With Ticagrelor in Patients With Coronary Artery DiseaseCompletedNCT01852175Not applicableResults posted
• Cangrelor Prasugrel Transition StudyCompletedNCT01852019Phase 2Results posted
• Ticagrelor Versus Clopidogrel in Type 2 Diabetic PatientsCompletedNCT01823510Phase 4Results posted
• Pharmacogenomics of Antiplatelet Response - ICompletedNCT01815008Phase 4Results posted
• Effect of Prasugrel Versus Clopidogrel on Platelet Function After Bivalirudin CessationCompletedNCT01789814Phase 4Results posted
• Cangrelor Ticagrelor Transition StudyCompletedNCT01766466Phase 2Results posted
• Platelet Inhibition in Patients With Systolic Heart FailureCompletedNCT01765400Phase 4Results posted
• Investigation of Drug-drug Interaction of Dabigatran and TicagrelorCompletedNCT01734772Phase 1Results posted
• A Study Comparing Cardiovascular Effects of Ticagrelor and Clopidogrel in Patients With Peripheral Artery DiseaseCompletedNCT01732822Phase 3Results posted
• Impact of Ticagrelor Re-load on Pharmacodynamic ProfilesCompletedNCT01731041Not applicableResults posted
• Antithrombotic Effects of Ticagrelor Versus ClopidogrelCompletedNCT01642238Phase 4Results posted
• Antiplatelet Therapy Guided by Thrombelastography in Patients With Acute Coronary Syndromes (TEGCOR Study)TerminatedNCT01612884Phase 4Results posted
• Ad Hoc Percutaneous Coronary Intervention Study in Acute Coronary Syndrome PatientsCompletedNCT01603082Phase 4Results posted
• Investigation of Pharmacodynamic Effects of Dabigatran and Ticagrelor and Assessment of Ticagrelor Interaction Potential With DabigatranCompletedNCT01595854Phase 1Results posted
• PROMUS Element Plus US Post-Approval StudyCompletedNCT01589978Phase 4Results posted
• Aspirin Resistance and Stroke Risk: Platelet Function Analysis in Patients With Ischemic EventsCompletedNCT01586975Phase 2/3Results posted
• A Pharmacodynamic Study With Ticagrelor in African American PatientsCompletedNCT01523392Phase 4Results posted
• A Pharmacodynamic Study With Ticagrelor in Hispanic PatientsCompletedNCT01523366Phase 4Results posted
• Pharmacogenomics of Anti-platelet Intervention-2 (PAPI-2) StudyTerminatedNCT01452152Phase 4Results posted
• A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)CompletedNCT01347580Phase 4Results posted
• Clopidogrel and Aspirin Interaction Study-2CompletedNCT01341964Phase 4Results posted
• Clopidogrel Pharmacogenetics (PGX) Bench to BedsideCompletedNCT01341600Not applicableResults posted
• Study to Assess Safety and Efficacy of Ticagrelor (AZD6140) Versus Clopidogrel in Asian/Japanese Patients With Non-ST or ST Elevation Acute Coronary Syndromes (ACS)CompletedNCT01294462Phase 3Results posted
• Investigation of the Athero-Protective Effects of ClopidogrelCompletedNCT01283282Phase 4Results posted
• A Pharmacokinetic Study on the Effect of LY2216684 on the Active Metabolite of ClopidogrelCompletedNCT01263093Phase 1Results posted
• Escalating Clopidogrel by Involving a Genetic Strategy - Thrombolysis In Myocardial Infarction 56CompletedNCT01235351Phase 2Results posted
• Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of AspirinCompletedNCT01225562Phase 3Results posted
• Aspirin and Plavix Following Coronary Artery Bypass GraftingTerminatedNCT01158703Phase 4Results posted
• A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)CompletedNCT01156571Phase 3Results posted
• Drug-Eluting Stents vs. Bare Metal Stents In Saphenous Vein Graft AngioplastyCompletedNCT01121224Phase 4Results posted
• An Asian Study to Assess the Properties and Profile of Ticagrelor in Patients With Stable Coronary Artery DiseaseCompletedNCT01118325Phase 2Results posted
• Clopidogrel to Prasugrel in Acute Coronary Syndrome (ACS) PatientsCompletedNCT01115738Phase 2Results posted
• Aspirin Resistance and Percutaneous Coronary Intervention (PCI)CompletedNCT01103440Phase 2Results posted
• Clopidogrel Pharmacogenomics ProjectCompletedNCT01097343Phase 2Results posted
• A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)CompletedNCT01012219Phase 1Results posted
• Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) TrialTerminatedNCT00991029Phase 3Results posted
• The Dual Antiplatelet Therapy Study (DAPT Study)CompletedNCT00977938Phase 4Results posted
• CYPRESS - CYPHER for Evaluating Sustained SafetyStatus unknownNCT00954707Phase 4Results posted
• A Study of the Effects of Multiple Doses of Dexlansoprazole, Lansoprazole, Omeprazole or Esomeprazole on the Pharmacokinetics and Pharmacodynamics of Clopidogrel in Healthy Participants.CompletedNCT00942175Phase 1Results posted
• Long Term Safety of Clopidogrel in Neonates/Infants With Systemic to Pulmonary Artery Shunt PalliationCompletedNCT00833703Phase 3Results posted
• The Impact of Grapefruit Juice on the Response to ClopidogrelCompletedNCT00817999Phase 4Results posted
• Determining Genetic Role in Treatment Response to Anti-Platelet Interventions (The PAPI Study)CompletedNCT00799396Phase 4Results posted
• Maintenance of Platelet Inhibition With CangrelorCompletedNCT00767507Phase 2Results posted
• The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac CatheterizationCompletedNCT00644657Not applicableResults posted
• A Study of the Antiplatelet Effects Comparing Ticagrelor (Ticag. - AZD6140) With Clopidogrel (Clop.) Responder and Non-respondersCompletedNCT00642811Phase 2Results posted
• PACT (Platelet Activity After Clopidogrel Termination)CompletedNCT00619073Not applicableResults posted
• A Study of the Onset and Offset of Antiplatelet Effects Comparing Ticagrelor, Clopidogrel, and Placebo With AspirinCompletedNCT00528411Phase 2Results posted
• Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt PalliationCompletedNCT00396877Phase 3Results posted
• A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary SyndromeCompletedNCT00391872Phase 3Results posted
• Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition.TerminatedNCT00385138Phase 3Results posted
• Trial in Subjects Undergoing Cardiac Catheterization With Planned Percutaneous Coronary Intervention With StentingCompletedNCT00357968Phase 2Results posted
• Clopidogrel Optimal Loading Dose Usage to Reduce Recurrent EveNTs/Optimal Antiplatelet Strategy for InterventionSCompletedNCT00335452Phase 3Results posted
• A Clinical Trial to Demonstrate the Efficacy of CangrelorTerminatedNCT00305162Phase 3Results posted
• A Study of the Effects of Inhibiting Platelet Function on Circulating Cancer Cells in Breast Cancer PatientsTerminatedNCT00263211Phase 2Results posted
• Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)CompletedNCT00249873Phase 3Results posted
• Trial of Clopidogrel After Surgery for Coronary Artery Disease (CASCADE Trial)CompletedNCT00228423Phase 2Results posted
• Combined Antiplatelet Strategy in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPRIME)CompletedNCT07844603Phase 2
• Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower Extremity RevascularizationActive, not recruitingNCT07597239Not applicable
• Investigation of Drug-drug Interaction of HRS-5965 With Clopidogrel and Clarithromycin in Healthy SubjectsCompletedNCT07040787Phase 1
• Evaluation of Platelet Aggregability in Patients with Non-small Cell Lung CarcinomasActive, not recruitingNCT06872541Phase 2/3
• A Drug-drug Interaction Study of YZJ-1139 Tablets and Ticagrelor Tablets in Healthy SubjectsCompletedNCT06671470Phase 1
• TISSARA Trial: Ticagrelor Intervention to Reduce Stent Thrombosis and Acute MI RiskCompletedNCT06667349Phase 4
• Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPrime)CompletedNCT06638151Phase 2
• Combining Aspirin With Cilostazol or Clopidogrel in Minor Stroke or TIAStatus unknownNCT06591299Phase 3
• A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy ParticipantsCompletedNCT06554821Phase 1
• TADCLOT- a Double Blind Randomized Controlled TrialCompletedNCT06318481Phase 3
• Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic StrokeCompletedNCT06316570Phase 3
• Clopidogrel Versus Cilostazol in Large-vessel Ischemic StrokeCompletedNCT06242145Phase 3

← P2Y12 inhibitors overview