Protein Kinase Inhibitors: all 15,278 studies that test it
Page 73 of 153. Open to participants first (2,556), then studies with results posted, then the rest; newest registration first within each.
- A Study to Investigate the Effect of Capivasertib on the Pharmacokinetics of Oral Rosuvastatin in Healthy ParticipantsCompletedNCT07088913Phase 1
- Durvalumab and Tremelimumab With Lenvatinib as First-line Treatment in Patients With Unresectable Hepatocellular CarcinomaActive, not recruitingNCT07081633Phase 2
- Upadacitinib for Refractory Behcet's SyndromeCompletedNCT07080346Phase 2
- Trametinib Treatment for Complicated Vascular AnomaliesActive, not recruitingNCT07072403Phase 1/2
- A Study of Exercise and Pharmacologic Intervention on Systemic InflammationActive, not recruitingNCT07058974Phase 1
- A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and AnemiaActive, not recruitingNCT07052006Phase 2
- A Study to Evaluate the Relative Bioavailability of Two Tablet Formulations Compared to Capsule Formulation and the Effect of Food and Proton Pump Inhibitor on ZN-A-1041 Tablet(s) in Healthy ParticipantsCompletedNCT07051993Phase 1
- Intranasal Administration of Dodecyl Creatine Ester (CBT101) in Healthy Male SubjectsCompletedNCT07050316Phase 1
- Vorolanib Monotherapy or in Combination With Toripalimab as Adjuvant Therapy for Patients With Intermediate-high Risk of Recurrence in Renal Cell CarcinomaActive, not recruitingNCT07047001Phase 2
- Efficacy of Oral Tofacitinib in Combination of Narrow Band UVB in Treatment of VitiligoActive, not recruitingNCT07044141Phase 1
- A Phase 1 Study of ATV-1601 in Patients With Advanced Cancer That Have AKT1 E17K MutationsActive, not recruitingNCT07038369Phase 1
- Radiotherapy Plus Anlotinib in LA-NSCLC Intolerable to cCRTCompletedNCT07037680Phase 2
- Clinical Study of Neflamapimod in Patients With Primary Progressive AphasiaActive, not recruitingNCT07033481Phase 2
- A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.CompletedNCT07032272Phase 1
- A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia AreataActive, not recruitingNCT07023302Phase 3
- A Study of the Pharmacokinetic Interaction Between Pirfenidone, Nintedanib, and Nalbuphine Extended Release (NAL ER) in Healthy ParticipantsCompletedNCT07015398Phase 1
- A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell CarcinomaActive, not recruitingNCT07010120Phase 1/2
- Fortifying Healthy Behaviors, Optimizing Medical Therapies and Enhancing Cognitive Function in Older Adults-pilot StudyCompletedNCT07000734Phase 2
- Efficacy and Tolerability of Deucravacitinib in the Management of Palmoplantar PustulosisTerminatedNCT07000630Not applicable
- A Study of Food Effect and Esomeprazole on LY4064809 in Healthy Adult ParticipantsCompletedNCT06991179Phase 1
- Long-term Safety and Efficacy of Leniolisib in PIDs With Immune DysregulationActive, not recruitingNCT06990529Phase 2
- A Clinical Study to Investigate the Effect of Oral Neflamapimod on Motor Recovery After Acute Ischaemic StrokeActive, not recruitingNCT06987643Phase 2
- TGRX-678 Pharmacokinetic Mass BalanceCompletedNCT06986772Phase 1
- A Study Comparing Zasocitinib (TAK-279) With Deucravacitinib in Adults With Plaque PsoriasisCompletedNCT06973291Phase 3
- Zanzalintinib in Combination With Ipilimumab and Nivolumab in Patients With Metastatic Soft Tissue SarcomaSuspendedNCT06968988Phase 1
- A Study of Filgotinib 200 mg in Korean Participants With Moderately to Severely Active Ulcerative Colitis Under Routine Clinical PracticeActive, not recruitingNCT06964113Phase 4
- An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal FunctionCompletedNCT06962774Phase 1
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS1)Active, not recruitingNCT06959225Phase 3
- Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)Active, not recruitingNCT06958211Phase 3
- Sirolimus for Injection (Albumin-bound) in Combination With Endocrine Therapy for HR+/HER2- Advanced/Metastatic Breast Cancer Patients Who Have Failed Standard TherapyActive, not recruitingNCT06957379Phase 2
- An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver DamageCompletedNCT06952634Phase 1
- Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis NigricansCompletedNCT06940895Phase 2
- A Single-arm, Multicenter Exploratory Clinical Trial of Anlotinib Combined With TQB2450 and the SOX Regimen as First-line Treatment for Advanced Gastric Cancer With Low PD-L1 ExpressionActive, not recruitingNCT06939452Phase 2
- A Study to Evaluate the Effect of Ceralasertib on Drug X, Drug Y and Drug ZTerminatedNCT06929260Phase 1
- Hepatoprotective Measures for Children at High Risk of NAFLDActive, not recruitingNCT06918080Phase 4
- A Study to Evaluate the Effect of Food on the Single-Dose Pharmacokinetics and a Drug-Drug Interaction Evaluation of Itraconazole and Carbamazepine on INCB123667 When Administered Orally to Healthy Adult ParticipantsCompletedNCT06909162Phase 1
- Regorafenib and Yttrium-90 Radioembolization for Unresectable Hepatocellular CarcinomaWithdrawnNCT06902246Phase 2
- A Study of LY4064809 [14C]-STX-478 in Healthy Male ParticipantsCompletedNCT06901336Phase 1
- Exploratory Study of Inhaled Afatinib Dimaleate PK ProfileTerminatedNCT06897735Phase 1
- A Study to Learn if the Study Medicine Called Carbamazepine Changes How the Body Processes PF-07220060CompletedNCT06897683Phase 1
- Carboplatin/Cisplatin + Etoposide + Benmelstobart Sequential Benmelstobart Combined With Anlotinib Versus Carboplatin/Cisplatin + Etoposide + Tislelizumab Sequential Tislelizumab in the Treatment of Extensive Stage Small Cell Lung CancerTerminatedNCT06897579Phase 2
- Leniolisib for Immune Dysregulation in CVIDCompletedNCT06897358Phase 2
- Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine GliomaActive, not recruitingNCT06894979Phase 1
- A Study to Evaluate the Effect of a High-fat Meal on the Exposure of Pimicotinib Capsule in Healthy SubjectsActive, not recruitingNCT06884072Phase 1
- A Study of Roginolisib (IOA-244) in Combination With Dostarlimab With or Without Docetaxel in Metastatic Non Small-cell Lung Cancer (NSCLC) PatientsActive, not recruitingNCT06879717Phase 1/2
- Combination Therapy (Mirdametinib and Sirolimus) for RAS Mutated Relapsed Refractory Multiple MyelomaSuspendedNCT06876142Phase 1/2
- A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistaminesActive, not recruitingNCT06868212Phase 3
- Study of Adaptive Immunotherapy With VEGFR-TKI in Patients With Advanced RCCSuspendedNCT06860386Phase 2
- Neoadjuvant Therapy for Locally Advanced Rectal CancerActive, not recruitingNCT06853769Early Phase 1
- A Study to Evaluate the Bioequivalence Between Immediate Release Tablets and Minitablets of Deucravacitinib (BMS-986165), and the Effect of Food and pH on the Drug Levels of the Minitablets in Healthy AdultsCompletedNCT06851871Phase 1
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis SuppurativaActive, not recruitingNCT06840392Phase 3
- A Study to Investigate the Sequencing Strategy of Pirtobrutinib After Disease Progression on First-line Acalabrutinib Treatment for Adult Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic LymphomaWithdrawnNCT06839872Phase 2
- A Study to Assess the Efficacy and Safety of PG-011 Nasal Spray in Adults With Moderate to Severe Seasonal Allergic RhinitisCompletedNCT06837233Phase 2
- A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children and Adolescents (6 to <18 Years Old) With Moderate Atopic DermatitisActive, not recruitingNCT06832618Phase 3
- Combination of Vebreltinib and Osimertinib in Patients with EGFR 21 L858R Mutation Advanced NSCLCActive, not recruitingNCT06827145Phase 2
- Tazemetostat in Combination With Zanubrutinib and Anti-CD20 Monoclonal Antibody in Relapsed or Refractory B-cell Non-Hodgkin LymphomaActive, not recruitingNCT06824701Phase 1
- A Study on the Substance Balance of [14C]XY0206 in Healthy Adult Chinese MenCompletedNCT06823232Phase 1
- Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the BodyTerminatedNCT06820957Phase 2/3
- A Clinical Study of Neflamapimod in Patients With Dementia With Lewy BodiesCompletedNCT06815965Phase 2
- High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal MetastasisCompletedNCT06812871Phase 2
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)Active, not recruitingNCT06799000Phase 3
- Ritlecitinib (PF-06651600) in Participants With Chronic Spontaneous UrticariaWithdrawnNCT06795373Phase 2
- A Study of AL8326 in Non-Small Cell Lung CancerActive, not recruitingNCT06794957Phase 1
- A Study of Interaction of Zasocitinib (TAK-279) With Other Medicines in Healthy AdultsCompletedNCT06793943Phase 1
- A Trial of SHR0302Base in Patients With VitiligoActive, not recruitingNCT06790862Phase 2
- Everolimus and/or Exercise to Prevent Bone Loss in Postmenopausal WomenActive, not recruitingNCT06789900Phase 2
- A Study to Investigate The Effect of Pimicotinib on The Pharmacokinetics of Metformin, Fexofenadine and Rosuvastatin In Healthy SubjectsCompletedNCT06779253Phase 1
- A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid TumorsActive, not recruitingNCT06777316Phase 1/2
- Upadacitinib for Prurigo NodularisTerminatedNCT06773403Phase 4
- A Study to Evaluate the Effect of Food on Nemtabrutinib (MK-1026) in Healthy Participants (MK-1026-017)CompletedNCT06772818Phase 1
- A Study to Evaluate the Effect of Food on Nemtabrutinib (MK-1026) in Healthy Participants (MK-1026-016)CompletedNCT06772805Phase 1
- A Study to Evaluate QTc Prolongation With Quizartinib in Healthy Subjects Under Rapid Acceleration of Heart RateCompletedNCT06772246Phase 1
- CART123 + Ruxolitinib in Relapsed/Refractory AMLActive, not recruitingNCT06768476Phase 1
- A Phase IIIB Study to Evaluate the Use of Capivasertib in Combination With Fulvestrant in Patients With Advanced Breast Cancer Who Have Relapsed/Progressed on ET and CDK4/6 Inhibitor Reflecting Real World Clinical Practice in SpainActive, not recruitingNCT06764186Phase 3
- A Study of Different Forms of BGB-43395 and Food Effect in Healthy ParticipantsCompletedNCT06761898Phase 1
- Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic DiseaseActive, not recruitingNCT06760637Phase 3
- Use of Selective JAK Inhibitor in ILD and Skin Tightness of Systemic Sclerosis Versus MMFCompletedNCT06758947Phase 3
- Human ADME Study of [14C]-Ceralasertib (AZD6738) and Absolute Bioavailability of CeralasertibTerminatedNCT06754761Phase 1
- Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic AnemiaActive, not recruitingNCT06752694Phase 2
- A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease PatientsCompletedNCT06745583Phase 2
- A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia GravisActive, not recruitingNCT06744920Phase 3
- A Clinical Study on Neoadjuvant Treatment of Resectable Head and Neck Squamous Carcinoma With Immune-targeted Therapy and Lysogenic HSV VirusWithdrawnNCT06741982Phase 1
- Study to Assess the Effect of a CYP3A Weak Inducer Rufinamide on Quizartinib Pharmacokinetics in Healthy SubjectsCompletedNCT06740825Phase 1
- A Phase 2 Study of CAL101 in Patients With Idiopathic Pulmonary FibrosisActive, not recruitingNCT06736990Phase 2
- Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic CancerActive, not recruitingNCT06736717Phase 1/2
- Study to Evaluate the Pharmacokinetics and Pharmacodynamics of AZD4604 Given Via the Turbuhaler® Device in Adults With Mild Asthma.CompletedNCT06732882Phase 1
- Testing the Addition of AZD6738 (Ceralasertib) to Immunotherapy to Increase Time Without Cancer for Patients With Non-Small Cell Lung CancerActive, not recruitingNCT06732401Phase 3
- Tyrosine Kinase 2 (TYK2) for GA and CSWithdrawnNCT06725264Phase 2
- A Randomised Phase II Study of Roginolisib in Patients With Advanced/Metastatic Uveal MelanomaActive, not recruitingNCT06717126Phase 2
- A Clinical Gene Therapy Study With Hematopoietic Stem Cells for the Treatment, With Single Dose of Temferon, of Patients Suffering From Metastatic Renal Cell CarcinomaTerminatedNCT06716853Phase 1/2
- Evaluation of TQB3616 Capsules in a Phase II Clinical Trial for Recurrent/Metastatic Breast CancerActive, not recruitingNCT06702618Phase 2
- Safety and Efficacy of Upadacitinib in Combination With Topical Corticosteroids in Children From 2 to Less Than 12 Years of Age in Japan With Moderate to Severe Atopic DermatitisActive, not recruitingNCT06701331Phase 3
- Phase II Clinical Study of Adebrelimab Combined with Apatinib in the Treatment of Locally Advanced Non-small Cell Lung Cancer Patients with Radiation PneumonitisActive, not recruitingNCT06700421Phase 2
- A Study of the Effect of Efavirenz on the Plasma Levels of Nemtabrutinib (MK-1026-014)CompletedNCT06698016Phase 1
- TGRX-678 Phase I Oral Pharmacokinetic StudyCompletedNCT06697899Phase 1
- ONO-4059 Study in Patients With Steroid-resistant PemphigusActive, not recruitingNCT06696716Phase 3
- Upfront Ruxolitinib for Chronic Graft-vs-host DiseaseTerminatedNCT06695507Phase 1
- A Study to Evaluate the Relative Bioavailability of Two Different Pimicotinib Capsules in Healthy SubjectsCompletedNCT06694948Phase 1
- A Study to Test How Zongertinib is Taken up in the Blood of People With and Without Liver ProblemsCompletedNCT06692322Phase 1
- A Study of the Effects of Itraconazole on the Plasma Levels of Nemtabrutinib (MK-1026-013)CompletedNCT06688045Phase 1