Protein Kinase Inhibitors: all 15,766 studies that test it

Page 137 of 158. Open to participants first (2,605), then studies with results posted, then the rest; newest registration first within each.

• Fulvestrant With or Without AZD6244 in Treating Patients With Advanced Breast Cancer That Progressed After Aromatase Inhibitor TherapyCompletedNCT01160718Phase 2
• Study of Sorafenib Maintenance in Patients With ED-SCLC After Response to Induction ChemotherapyTerminatedNCT01159327Phase 2
• Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid LeukemiaTerminatedNCT01159301Phase 1
• Sorafenib. ICORG 06-41, V4CompletedNCT01158287Phase 2
• Everolimus and LongActing Octreotide Trial in Polycystic LiversCompletedNCT01157858Phase 2
• Phase 1 Nilotinib in Steroid Dependent/Refractory Chronic Graft Versus Host DiseaseCompletedNCT01155817Phase 1
• Bioavailability and Food Effect Study of TKI258 (CSF Capsule vs. FMI Tablet) in Adult Patients With Advanced Solid TumorsCompletedNCT01155713Phase 1
• A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor PatientsCompletedNCT01155453Phase 1
• Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid TumorsCompletedNCT01155258Phase 1
• Everolimus MICE-regimen in Treating Older Patients With Newly Diagnosed Acute Myeloid LeukemiaCompletedNCT01154439Phase 1
• A Study to Evaluate Pazopanib Tablets in Patients Who Have Neovascular Age-related Macular DegenerationCompletedNCT01154062Phase 1
• Efficacy of Imatinib and 5-FU/Leucovorin in Patients With Advanced Carcinoma of the Gallbladder and Bile DuctCompletedNCT01153750Phase 2
• A Study to Evaluate the Effect on 24-hour, Intragastric pH of RAB ER 50-mg Capsules Compared With Esomeprazole (Nexium) 40 mg Capsules and Rabeprazole (Aciphex) 20-mg TabletsCompletedNCT01153659Phase 1
• PF-00299804 Monotherapy in Patients With HER-2 Positive Advance Gastric CancerCompletedNCT01152853Phase 2
• Study of RAD001 in Adenoid Cystic CarcinomaCompletedNCT01152840Phase 2
• RAD001 in Pheochromocytoma or Nonfunctioning CarcinoidCompletedNCT01152827Phase 2
• Safety of RAD001 in Chinese Patients With Metastatic Renal Cell CancerCompletedNCT01152801Phase 1
• Study of ARQ 197 MonotherapyCompletedNCT01152645Phase 2
• Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Reference in Subjects With Advanced Solid TumorsCompletedNCT01149720Phase 1
• Preventive Effect of Enoxaparin, Pentoxifylline and Ursodeoxycholic Acid to Radiation Induced Liver ToxicityCompletedNCT01149304Phase 2
• Gemcitabine/Oxaliplatin (GEMOX) With or Without Erlotinib (Tarceva) in Advanced Biliary Tract CarcinomaCompletedNCT01149122Phase 3
• A Study of Foretinib in Patients With Recurrent/Metastatic Breast CancerCompletedNCT01147484Phase 2
• Dose Defining Study For MK-2206 Combined With Gefitinib In Non Small Cell Lung Cancer (NSCLC)Status unknownNCT01147211Phase 1
• MEK Inhibitor and Thoracic Radiotherapy TrialCompletedNCT01146756Phase 1
• Japanese Phase 1 Study of BMS-844203 (CT322)WithdrawnNCT01146171Phase 1
• A Study of AT9283 in Patients With Relapsed or Refractory Multiple MyelomaCompletedNCT01145989Phase 2
• Trial of Lapatinib Versus Lapatinib With Capecitabine in Her2+ Metastatic Gastro-Esophageal CancerTerminatedNCT01145404Phase 2
• Study of Bafetinib as Treatment for Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL)CompletedNCT01144260Phase 2
• A Study To Estimate The Amount Of CP-690,550 (Study Drug) That Is Absorbed Into The Blood Of Healthy Subjects Following Oral Administration Of CP-690,550 In Tablet FormCompletedNCT01143805Phase 1
• A Study of RO5212054 (PLX3603) in Participants With BRAF V600-Mutated Advanced Solid TumorsCompletedNCT01143753Phase 1
• Cholestatic Drug-induced Liver InjuryStatus unknownNCT01141322Phase 4
• Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid CancerActive, not recruitingNCT01141309Phase 2
• Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refractory Solid TumorsCompletedNCT01141244Phase 1
• A Study of Axitinib in Patients With Advanced Angiosarcoma and Other Soft Tissue SarcomasCompletedNCT01140737Phase 2
• Safety Study of the Combination of Panitumumab, Irinotecan and Everolimus in the Treatment of Advanced Colorectal CancerCompletedNCT01139138Phase 1/2
• Study of Foretinib in Combination With Lapatinib in Patients With Metastatic Breast CancerCompletedNCT01138384Phase 1/2
• Safety, Pharmacokinetics (PK) of AKT and MEK CombinationCompletedNCT01138085Phase 1
• Study of a Focal Adhesion Kinase Inhibitor in Subjects With Solid TumorsCompletedNCT01138033Phase 1
• A Phase II, Randomized, Open-label Study of Lapatinib Plus Chemotherapy Versus Trastuzumab Plus Chemotherapy in HER2-positive and p95HER2-positive Metastatic Breast CancerWithdrawnNCT01137994Phase 2
• Study to Evaluate Imatinib in Desmoid TumorsCompletedNCT01137916Phase 2
• Study of Vinblastine and Sirolimus in Children With Recurrent/Refractory Solid Tumours Including CNS TumoursCompletedNCT01135563Phase 1
• Study to Compare Selective Internal Radiation Therapy (SIRT) Versus Sorafenib in Locally Advanced Hepatocellular Carcinoma (HCC)Status unknownNCT01135056Phase 3
• A Study in Myeloproliferative DisordersCompletedNCT01134120Phase 1
• Preoperative Chemotherapy With Paclitaxel, Gemcitabine, and Lapatinib (Tykerb®) (PGT)CompletedNCT01133912Phase 1
• Trial of S-1 in Combination With Sorafenib for Patients With Advanced Hepatocellular CarcinomaCompletedNCT01131689Phase 1
• A Chinese Randomized Crossover Study of Erlotinib Versus Docetaxel/Cisplatin in Previously Untreated Stage IIIB/IV Lung Adenocarcinoma With EGFR MutationsStatus unknownNCT01131429Phase 2
• Gamma-Secretase Inhibitor RO4929097 and Cediranib Maleate in Treating Patients With Advanced Solid TumorsCompletedNCT01131234Phase 1
• The Continuation of ErlotinibStatus unknownNCT01130779Phase 2
• Efficacy of Erlotinib in Neoadjuvant Setting in Patients With Stage IIIA, N2-positive Non-Small Cell Lung CancerCompletedNCT01130753Phase 2
• A Phase I Study of Pazopanib as a Single Agent for Children With Refractory Solid TumorsWithdrawnNCT01130623Phase 1
• Sorafenib Plus S-1 in Advanced Solid TumorsCompletedNCT01128998Phase 1
• A Study of Nilotinib in Adult Patients With Imatinib Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic PhaseCompletedNCT01126892Phase 3
• A Study of Imatinib With Reinduction Chemotherapy Using Mitoxantrone, Etoposide and Cytarabine in Patients With Relapsed/Refractory C-kit Positive (AML) Acute Myeloid LeukemiaCompletedNCT01126814Phase 1/2
• A Study To Investigate The Taste Of Crizotinib Liquid In Trained Healthy Adult VolunteersCompletedNCT01125904Phase 1
• Dose Escalation Study of Gemcitabine and ON 01910.Na in Solid TumorsCompletedNCT01125891Phase 1
• Epirubicin Hydrochloride, Cisplatin, and Fluorouracil or Capecitabine With or Without Lapatinib Ditosylate as First-Line Therapy in Treating Patients With Stomach Cancer or Gastroesophageal Junction CancerTerminatedNCT01123473Phase 2
• Sunitinib Plus Temsirolimus in Patients With Renal Cell Cancer (RCC)CompletedNCT01122615Phase 1
• Study of RAD001 + AMG479 for Patients With Advanced Solid TumorsCompletedNCT01122199Phase 1
• Treatment of Polycythemia Vera With GleevecCompletedNCT01120821Phase 2
• Dose Escalation Study of MLN0128 in Relapsed or Refractory Multiple Myeloma or Waldenstrom MacroglobulinemiaCompletedNCT01118689Phase 1
• Aurora B/C Kinase Inhibitor GSK1070916A in Treating Patients With Advanced Solid TumorsCompletedNCT01118611Phase 1
• Everolimus in Treating Patients With Progressive or Recurrent, Unresectable, or Metastatic Thyroid CancerStatus unknownNCT01118065Phase 2
• Sunitinib Malate in Treating Patients With Locally Recurrent, Locally Advanced, Unresectable, or Metastatic Urinary Tract CancerStatus unknownNCT01118039Phase 2
• Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative TreatmentCompletedNCT01116843Phase 1/2
• Erlotinib (Tarceva) and Bexarotene (Targretin) Oral Capsules in Advanced Cancers of the Aerodigestive TractCompletedNCT01116622Phase 1
• Phase I Chemoprevention Trial With Green Tea Polyphenon E & Erlotinib in Patients With Premalignant Lesions of the Head & NeckCompletedNCT01116336Phase 1
• Study of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With ColorecCompletedNCT01116271Phase 2
• Bevacizumab, Pemetrexed Disodium, and Cisplatin or Erlotinib Hydrochloride and Bevacizumab in Treating Patients With Stage IV Non-Small Cell Lung Cancer. A Multicenter Phase II Trial Including Biopsy at Progression (BIO-PRO Trial).CompletedNCT01116219Phase 2
• Dasatinib in Combination With Melphalan and Prednisone to Treat Relapsed and Refractory Multiple Myeloma PatientsTerminatedNCT01116128Phase 2
• A Phase 1 Study in Participants With Advanced CancerCompletedNCT01115790Phase 1
• A Study in Patients With Advanced or Metastatic CancerCompletedNCT01115751Phase 1
• A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Linifanib (ABT-869)CompletedNCT01114191Phase 1
• PF-00299804 in Adult Patients With Relapsed/Recurrent GlioblastomaCompletedNCT01112527Phase 2
• Study to Assess Safety, Tolerability and PK of AZD1480 in Patients With Solid TumoursTerminatedNCT01112397Phase 1
• Temsirolimus in Myelodysplastic Syndrome (MDS)TerminatedNCT01111448Phase 2
• Trial of PD 0332991 Plus Bortezomib in Patients With Relapsed Mantle Cell LymphomaTerminatedNCT01111188Phase 1
• Evaluation of Nilotinib In Patients With Advanced Gastrointestinal Stromal Tumor (GIST)CompletedNCT01110668Phase 2
• ABT-348 as Monotherapy or Combination With Carboplatin or Docetaxel to Treat Advanced Solid TumorsCompletedNCT01110486Phase 1
• ABT-348 as Monotherapy and in Combination With Azacitidine to Treat Advanced Hematologic MalignanciesCompletedNCT01110473Phase 1
• First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid TumorsTerminatedNCT01110083Phase 1
• Efficacy Study in Lumbosacral RadiculopathyCompletedNCT01110057Phase 2
• Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib TreatmentTerminatedNCT01108705Phase 3
• Pilot Study of Neo-Adjuvant Everolimus to Treat Advanced Renal Cell Carcinoma - Analysis of BiomarkersCompletedNCT01107509Not applicable
• A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of GDC-0623 in Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT01106599Phase 1
• Study of Oral ENMD-2076 Administered to Patients With Ovarian CancerCompletedNCT01104675Phase 2
• Trastuzumab or Lapatinib Ditosylate in Treating Women With Early Breast CancerActive, not recruitingNCT01104571Phase 3
• Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant GliomaTerminatedNCT01103375Phase 1
• CP-690,550 Pharmacokinetics In Healthy Chinese SubjectsCompletedNCT01101919Phase 1
• A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCCTerminatedNCT01101906Phase 2
• A Drug-Drug Interaction Study of the Effects of XL184 (Cabozantinib) on Rosiglitazone in Subjects With Solid TumorsCompletedNCT01100619Phase 1
• Study of Sunitinib Before and During Radiotherapy in Newly Diagnosed Biopsy-only Glioblastoma PatientsCompletedNCT01100177Phase 2
• Study of Pazopanib Monotherapy in Patients With Unresectable, Metastatic Neuroendocrine TumorCompletedNCT01099540Phase 2
• A Trial of RAD001/Capecitabine in Refractory Gastric CancerCompletedNCT01099527Phase 1/2
• Study of Nilotinib in Metastatic Melanoma With KIT AberrationsCompletedNCT01099514Phase 2
• AS703569 and Gemcitabine Combination in Advanced MalignanciesCompletedNCT01097512Phase 1
• Perifosine Plus Capecitabine Versus Placebo Plus Capecitabine in Patients With Refractory Advanced Colorectal CancerCompletedNCT01097018Phase 3
• A Study to Explore Efficacy and Safety of ASP015K in Subjects With Moderate to Severe PsoriasisCompletedNCT01096862Phase 2
• A Study of TS-1, Cisplatin (CDDP) and RAD001 (Everolimus)TerminatedNCT01096199Phase 1
• Phase I Study of BAY73-4506 in Chinese Patients With Advanced, Refractory Solid TumorsCompletedNCT01096030Phase 1
• Late Chronic Phase Chronic Myelogenous LeukemiaCompletedNCT01092741Phase 2

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