Protein Kinase Inhibitors: all 15,147 studies that test it

Page 125 of 152. Open to participants first (2,533), then studies with results posted, then the rest; newest registration first within each.

• Icotinib as First-line and Maintenance Treatment in EGFR Mutated Patients With Lung AdenocarcinomaStatus unknownNCT01665417Phase 4
• Effects of the Use of "de Novo" Everolimus in Renal Tranplant PopulationStatus unknownNCT01663805Phase 4
• Gemcitabine Hydrochloride, Dasatinib, and Erlotinib Hydrochloride in Treating Patients With Pancreatic Cancer That Is Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT01660971Phase 1
• A Phase 2, Single-Arm, Open-Label Study Evaluating the Efficacy and Safety of Single Agent GS 1101 (CAL 101) as Therapy for Previously Treated Chronic Lymphocytic LeukemiaWithdrawnNCT01659047Phase 2
• A Study to Look at the Electrical Activity of the Heart in Subjects With Solid Tumor Cancers, Before and After Receiving the Study Treatment, GSK1120212CompletedNCT01658553Phase 1
• Phase II Study of Docetaxel +/- Nintedanib in Breast CancerCompletedNCT01658462Phase 2
• ErbB2 Positive Metastatic Breast CancerTerminatedNCT01658358Phase 1/2
• Study Of PF-04691502 (PI3K/mTOR Inhibitor) In Combination With Exemestane Compared With Exemestane Alone In Patients With Advanced Breast CancerWithdrawnNCT01658176Phase 2
• Pilot Study Of Sirolimus Plus Multiagent Chemotherapy For Relapsed/Refractory Acute Lymphoblastic Leukemia/LymphomaTerminatedNCT01658007Early Phase 1
• Study of XL888 With Vemurafenib for Patients With Unresectable BRAF Mutated Stage III/IV MelanomaCompletedNCT01657591Phase 1
• Phase I, Dose Escalation of SAR125844 in Asian Solid Tumor PatientsCompletedNCT01657214Phase 1
• A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic MelanomaCompletedNCT01656642Phase 1
• Study of ARQ 197 in Hepatocellular Carcinoma (HCC)CompletedNCT01656265Phase 1
• Tivantinib and Topotecan Hydrochloride in Treating Patients With Advanced or Metastatic Solid TumorsCompletedNCT01654965Phase 1
• A Phase 2a, Efficacy and Safety Study of Duvelisib in Mild Asthmatic SubjectsCompletedNCT01653756Phase 2
• A Study of Famitinib Malate in HER2-negative Metastatic Breast CancerCompletedNCT01653574Phase 2
• A Study of Apatinib in Non-triple-negative Metastatic Breast CancerCompletedNCT01653561Phase 2
• STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell LymphomaStatus unknownNCT01653067Phase 2
• Certican (Everolimus) for Recipients of Kidney From HLA-identical Living DonorsCompletedNCT01653041Phase 4
• A Study of Dinaciclib in Combination With Rituximab in Participants With Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (P07974)CompletedNCT01650727Phase 1
• Study of Erlotinib and Metformin in Triple Negative Breast CancerCompletedNCT01650506Phase 1
• A Study to Evaluate the Efficacy and Safety of ASP015K in Moderate to Severe Rheumatoid Arthritis SubjectsCompletedNCT01649999Phase 2
• Exercise and Low-Dose Rapamycin in Older Adults With CAD:Cardiac Rehabilitation And Rapamycin in Elderly (CARE) TrialCompletedNCT01649960Phase 1
• A Study of MEK162 and Paclitaxel in Patients With Epithelial Ovarian, Fallopian Tube or Peritoneal CancerCompletedNCT01649336Phase 1
• Study of Everolimus Treatment in Newly-diagnosed Patients With Advanced Gastrointestinal Neuroendocrine TumorsTerminatedNCT01648465Phase 2
• Relative Bioavailibilty for Pediatric Powder for Suspension (PfOS) FormulationCompletedNCT01647659Phase 1
• First-line Treatment With Icotinib in Elder NSCLC EGFR Mutated PatientsStatus unknownNCT01646450Phase 4
• Phase I Study of Fruquintinib(HMPL-013) in Patients With Advanced Solid TumorsCompletedNCT01645215Phase 1
• Weekly Paclitaxel With or Without Pazopanib in Platinum Resistant or Refractory Ovarian CancerCompletedNCT01644825Phase 2
• Lenalidomide and Idelalisib in Treating Patients With Recurrent Follicular LymphomaCompletedNCT01644799Phase 1
• Study of the Combination of Crizotinib and Dasatinib in Pediatric Research Participants With Diffuse Pontine Glioma (DIPG) and High-Grade Glioma (HGG)CompletedNCT01644773Phase 1
• Phase 1b Safety and Efficacy Study of TRU-016TerminatedNCT01644253Phase 1
• Ruxolitinib and Pomalidomide Combination Therapy in Patients With Primary and Secondary MFCompletedNCT01644110Phase 1/2
• Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic MalignanciesTerminatedNCT01643603Phase 1
• Dasatinib and Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumors or Other Sarcomas That Cannot Be Removed by Surgery or Are MetastaticCompletedNCT01643278Phase 1
• Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG CriteriaTerminatedNCT01642017Phase 1
• Phase II Front-line Ponatinib in Adult Philadelphia+/BCR-ABL+ Acute Lymphoblastic Leukemia.CompletedNCT01641107Phase 2
• Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney TransplantationCompletedNCT01640743Not applicable
• Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients With Advanced Breast and Gastrointestinal TumorsCompletedNCT01640665Phase 1
• Phase I Study of MLN8237 and Pazopanib in Patients With Solid TumorsCompletedNCT01639911Phase 1
• Phase 2 Study - Aurora + Angiogenic Kinase Inhibitor ENMD-2076 in Previously Treated Locally Advanced + Metastatic TNBCCompletedNCT01639248Phase 2
• Cetuximab and Everolimus in Treating Patients With Metastatic or Recurrent Colon Cancer or Head and Neck CancerCompletedNCT01637194Phase 1
• Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.CompletedNCT01636908Not applicable
• Study of Vemurafenib, Carboplatin, and PaclitaxelCompletedNCT01636622Phase 1
• Dovitinib in Neuroendocrine TumorsCompletedNCT01635907Phase 2
• A Randomized, Open Label Study to Compare the Current Phase II and Planned Phase III Capsule Formulation of AZD6244CompletedNCT01635023Phase 1
• Study of Safety and Preliminary Efficacy for LDK378 in Japanese Patients With Genetic Alterations in Anaplastic Lymphoma Kinase (ALK)CompletedNCT01634763Phase 1
• A Study of Escalating Doses of Itacitinib Administered Orally in Patients With Plaque PsoriasisCompletedNCT01634087Phase 2
• Phase Ib of Abiraterone Acetate Plus BEZ235 or BKM120 in Castration-resistant Prostate Cancer (CRPC) PatientsCompletedNCT01634061Phase 1
• An Open Label Study of Itacitinib Administered Orally in Patients With MyelofibrosisCompletedNCT01633372Phase 2
• The Vienna RAP Pilot StudyCompletedNCT01632605Not applicable
• A Dose Escalation Trial of PR610 Treating Patients With Solid TumorsTerminatedNCT01631279Phase 1/2
• A Single-Dose Study of Tivozanib in Subjects With Hepatic Impairment and Normal Hepatic FunctionCompletedNCT01631097Phase 1
• Renal Transplantation in the Elderly - nEverOld StudyStatus unknownNCT01631058Phase 4
• PGL5001 Proof of Concept Study in Inflammatory EndometriosisCompletedNCT01630252Phase 2
• Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop TrialStatus unknownNCT01627132Phase 2
• A Study to Assess the Effect of Ketoconazole on the Pharmacokinetics of Ibrutinib in Healthy ParticipantsCompletedNCT01626651Phase 1
• A Study Exploring the Safety, Tolerability, and Efficacy of a 28 Day Course Followed by an Additional 56 Day Course of Itacitinib in Subjects With Active Rheumatoid ArthritisCompletedNCT01626573Phase 2
• 4EVER - Efficacy, Safety, Health Economics, Translational Research of Postmenopausal Women With Estrogen Receptor Positive Locally Advanced or Metastatic Breast CancerCompletedNCT01626222Phase 3
• A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid TumorsCompletedNCT01626209Phase 1
• Tivantinib and Temsirolimus in Treating Patients With Solid Tumors That is Metastatic or Cannot be Removed by SurgeryCompletedNCT01625156Phase 1
• Dinaciclib and Epirubicin Hydrochloride in Treating Patients With Metastatic Triple-Negative Breast CancerCompletedNCT01624441Phase 1
• Sorafenib Tosylate Following a Liver Transplant in Treating Patients With Liver CancerCompletedNCT01624285Phase 2
• Phase I Study of the Oral PI3kinase Inhibitor BKM120 or BYL719 and the Oral PARP Inhibitor Olaparib in Patients With Recurrent Triple Negative Breast Cancer or High Grade Serous Ovarian CancerCompletedNCT01623349Phase 1
• Rapamune Improves Outcomes of Severe H1N1 PneumoniaCompletedNCT01620307Phase 2
• Radiation Therapy With Sorafenib for TACE-Resistant Hepatocellular CarcinomaWithdrawnNCT01618253Phase 1
• Study of PX-866 and Vemurafenib in Patients With Advanced MelanomaTerminatedNCT01616199Phase 1/2
• A Clinical Trial Evaluating the Effect of ASLAN001 in Patients With Recurrent/Metastatic Gastric Cancer Whose Tumors Are Either HER-2 Amplified or Co-expressing HER-1 and HER-2CompletedNCT01614522Phase 2
• PI3K Inhibitor BYL719 in Combination With the HSP90 Inhibitor AUY922 in Patients With Advanced or Metastatic Gastric CancerCompletedNCT01613950Phase 1
• Phase III Sequential Open-label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Pazopanib Versus Pazopanib Followed by Sorafenib in the Treatment of Advanced / Metastatic Renal Cell Carcinoma (SWITCH-II)CompletedNCT01613846Phase 3
• Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical CancerWithdrawnNCT01613677Phase 2
• Study of TAK-733 in Combination With Alisertib in Adult Patients With Advanced Nonhematologic MalignanciesWithdrawnNCT01613261Phase 1
• Effects of Zortress® + Tacrolimus vs. Standard Immunosuppression on Progression of Coronary Artery Calcifications and Bone Disease in de Novo Renal Transplant RecipientsWithdrawnNCT01612299Not applicable
• Leflunomide+Vemurafenib in V600 Mutant Met. MelanomaTerminatedNCT01611675Phase 1
• A Phase 1 Open-Label Study to Evaluate the Metabolism and Excretion of CC-223 and the Effect of Food on the Pharmacokinetics of CC-223 in Healthy Male Adult SubjectsCompletedNCT01611467Phase 1
• Study With Temsirolimus Added to Standard Chemotherapy for Patients Over 60 Years With Acute Myeloblastic LeukemiaCompletedNCT01611116Phase 2
• Low Dose Cyclophosphamide +/-- Nintedanib in Advanced Ovarian CancerCompletedNCT01610869Phase 2
• Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin LymphomaTerminatedNCT01609816Phase 1
• Study of Everolimus in de Novo Renal Transplant RecipientsTerminatedNCT01609673Not applicable
• The Role of EGFR Mutations in Pancreatic Cancer Patients Receiving Gemcitabine With or Without ErlotinibStatus unknownNCT01608841Phase 2
• A Single and Multiple Dose Study to Assess Blood and Urine Drug Levels of Fostamatinib in Healthy Japanese SubjectsCompletedNCT01608542Phase 1
• A Clinical Trial to Assess the Efficacy and Safety of the Conversion to EverolimusStatus unknownNCT01608412Phase 4
• Study of Curcumin, Vorinostat, and SorafenibWithdrawnNCT01608139Phase 1
• [18F]Fluciclatide-PET, Pazopanib and Paclitaxel in Ovarian CancerCompletedNCT01608009Phase 1
• Trial Evaluating Nilotinib as Treatment for Newly Diagnosed CML Patients in Accelerated Phase.WithdrawnNCT01605981Phase 4
• A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid MalignanciesSuspendedNCT01604863Phase 1
• Philadelphia Chromosome Positive CML Patients Without Optimal Response or Tolerance to Bcr-Abl TKICompletedNCT01602952Phase 1/2
• Relative Bioavailability StudyCompletedNCT01602887Phase 1
• A Study of LY2875358 in Japanese Participants With Advanced CancerCompletedNCT01602289Phase 1
• Clinical Trial Comparing Gemcitabine and Vandetanib Therapy With Gemcitabine Alone in Pancreatic CarcinomaCompletedNCT01601808Phase 2
• OSI-906 With Gemcitabine and Erlotinib for Metastatic Ductal Adenocarcinoma of the PancreasWithdrawnNCT01600807Phase 1/2
• A Study to Evaluate the Efficacy and Safety of Ibrutinib, in Patients With Mantle Cell Lymphoma Who Progress After Bortezomib TherapyCompletedNCT01599949Phase 2
• Tofacitinib Bioequivalence Study Comparing Tablets And CapsulesCompletedNCT01599377Phase 1
• Study in Healthy Males to Assess Bioavailability of Single Fostamatinib With iv Micro Tracer DoseCompletedNCT01598571Phase 1
• A Study of JNJ-40346527 in Patients With Active Rheumatoid Arthritis Despite Disease-modifying Antirheumatic Drug TherapyCompletedNCT01597739Phase 2
• Pharmacokinetic Drug-drug Interaction Study of Dovitinib (TKI258) in Patients With Advanced Solid TumorsCompletedNCT01596647Phase 1
• A Study of the Safety and Pharmacokinetics of SAR245409 Tablets in Patients With Solid Tumors or LymphomaCompletedNCT01596270Phase 1
• Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced CancerCompletedNCT01596140Phase 1
• Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME)CompletedNCT01595984Phase 3
• Sirolimus Use in Angioplasty for Vascular Access ExtensionCompletedNCT01595841Phase 2

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