Praliciguat clinical trials
Also written IW-1973.
How each study uses praliciguat is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Development codes
- IW-1973
- 6
Studies by the year they started
8 studies that test it; most in 2017 (3)
| Year | Studies |
|---|---|
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 3 |
| 2018 | 1 |
| 2019 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 8 · Other 0
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 1
Studies that test praliciguat.
- Jun 2027A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)Phase 2 · Akebia Therapeutics
Studies
Open first, then newest update. How each study uses praliciguat is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 8
- A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)RecruitingPhase 2Akebia TherapeuticsNCT07268638Written as Praliciguat (Part A)
- A Study to Evaluate the Soluble Guanylate Cyclase (sGC) Stimulator IW-1973 in Diabetic Nephropathy / Diabetic Kidney Disease as Measured by AlbuminuriaCompletedPhase 2Akebia TherapeuticsNCT03217591Written as IW-1973
- A Study of the Effect of IW-1973 on the Exercise Capacity of Patients With Heart Failure With Preserved Ejection Fraction (HFpEF)CompletedPhase 2Akebia TherapeuticsNCT03254485Written as IW-1973
- Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC) in Patients With Stable Type 2 Diabetes and HypertensionCompletedPhase 2Cyclerion TherapeuticsNCT03091920Written as IW-1973
- A Phase 2 Trial of IW-1973, A Stimulator of Soluble Guanylate Cyclase (sGC), in Patients With Stable Type 2 Diabetes and HypertensionCompletedPhase 2Cyclerion TherapeuticsNCT02906579Written as IW-1973
- A Trial to Study the Absorption, Metabolism, and Excretion of [14C]-Praliciguat in Healthy Male VolunteersCompletedPhase 1Cyclerion TherapeuticsNCT03818295Written as [14C]-praliciguat
- A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy VolunteersCompletedPhase 1Cyclerion TherapeuticsNCT03499106Written as IW-1973
- Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy VolunteersCompletedPhase 1Cyclerion TherapeuticsNCT02616861Written as IW-1973
Codes
What other systems call praliciguat · ClinicalTrials.gg INT001105
- MeSH (NLM) C000631485praliciguatConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) R1S0H458SAPRALICIGUATConfirmed FDA, NLM, Wikidata
- Wikidata Q106029653praliciguatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C174906PraliciguatOne source FDA
- DrugBank DB16300One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C000631485 | praliciguat | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | R1S0H458SA | PRALICIGUAT | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q106029653 | praliciguat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C174906 | Praliciguat | One source FDA |
| DrugBank | DB16300 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.