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PLX8394 clinical trials

Also written Plixorafenib, FORE8394 and PLX8394.

studies test it
6
open now
3
in phase 3
0
first study started
2014

How each study uses PLX8394 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

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Approvals

The first approval found in each region, with its record

United States
Not in FDA's approval records
European Union
Not in EMA's list of EU-wide authorisations

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Development codes

FORE8394
3
PLX8394
2

Other names

Plixorafenib
4

Studies by the year they started

5 studies that test it; most in 2014 (1); 1 more planned to start later

Studies that test PLX8394, by start year
YearStudies
20141
20151
20231
20241
20251

By phase

A phase 1/2 study counts in both.

Early Phase 1
2
Phase 1
3
Phase 2
2

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Glioblastoma
1
Melanoma
1

Who runs them

Industry 4 · Other 2

Fore Biotherapeutics (4) · Olivia Newton-John Cancer Research Institute (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)

Often tested with

Tested in the same studies.

Cobicistat (1) · Larotrectinib (1) · Cadonilimab (1)

Related medicines

As reviewed, each with the page that says it.

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Reaching primary completion within a year · 1

Studies that test PLX8394.

Studies

Open first, then newest update. How each study uses PLX8394 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 6

Codes

What other systems call PLX8394 · ClinicalTrials.gg INT000341

  • UNII (FDA) J2L7Z273SGPLIXORAFENIBConfirmed FDA, Wikidata
  • Wikidata Q27088419PLX8394Confirmed FDA, Wikidata
  • DrugBank DB16038One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.