Drug
Olverembatinib clinical trials
Also written HQP1351.
- studies test it
- 27
- open now
- 18
- in phase 3
- 4
- first study started
- 2018
Keep track of what changes. Save the olverembatinib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Studies by the year they started
26 studies that test it; most in 2022 (6); 1 more planned to start later
| Year | Studies |
|---|---|
| 2018 | 1 |
| 2019 | 5 |
| 2022 | 6 |
| 2023 | 3 |
| 2024 | 6 |
| 2025 | 4 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 8
- Phase 2
- 15
- Phase 3
- 4
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 18
Ascentage Pharma Group Inc. (9) · Institute of Hematology & Blood Diseases Hospital, China (6) · M.D. Anderson Cancer Center (3) · The First Affiliated Hospital of Soochow University (3) · First Affiliated Hospital of Zhejiang University (1) · Nanfang Hospital, Southern Medical University (1) · Xijing Hospital (1) · Chen Suning (1)
Often tested with
Tested in the same studies.
Venetoclax (6) · Blinatumomab (3) · Dexamethasone (2) · Inotuzumab Ozogamicin (1) · Decitabine (1) · Lisaftoclax (1) · Allogeneic Anti-CD19 T-cells ThisCART19A (1) · Chimeric Antigen Receptor T-cells (1)
Studies
Open first, then newest update. How each study uses olverembatinib is read from its arms, and is right about nine times in ten.
Testing it · 27
- Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)Not yet recruitingPhase 2M.D. Anderson Cancer CenterNCT07178912Written as olverembatinib
- Phase II Study Assessing the Efficacy and Toxicity of Olverembatinib Monotherapy in Patients With Chronic Myeloid Leukemia in Chronic Phase After Failing One Prior Therapy With a Second Generation Tyrosine Kinase Inhibitor or AsciminibRecruitingPhase 2M.D. Anderson Cancer CenterNCT06817720Written as olverembatinib
- Immunotargeted Therapy Plus Low-Dose Chemotherapy in Newly Diagnosed Adult Ph+ B-ALLNot yet recruitingPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT07840976Written as olverembatinib
- A Phase I Study of Decitabine, Lisaftoclax, and Olverembatinib in Patients With Advanced Chronic Myeloid Leukemia and Philadelphia Chromosome-Positive Acute Myeloid LeukemiaRecruitingPhase 1M.D. Anderson Cancer CenterNCT06401603Written as Olverembatinib
- Study for Safety and Efficacy of Olverembatinib Combined With APG-2575 in Children With Relapsed/Refractory Ph + ALLRecruitingPhase 1Institute of Hematology & Blood Diseases Hospital, ChinaNCT05495035Written as Olverembatinib, APG-2575, Dexamethasone
- A Study of Olverembatinib in SDH-deficient GIST.RecruitingPhase 3Ascentage Pharma Group Inc.NCT06640361Written as Olverembatinib
- Efficacy, Safety, and Pharmacokinetics of ThisCART19A Combined With Olverembatinib in Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.RecruitingEarly Phase 1The First Affiliated Hospital of Soochow UniversityNCT07074496Written as Olverembatinib
- A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)RecruitingPhase 3Ascentage Pharma Group Inc.NCT06051409Written as Olverembatinib
- A Study of HQP1351 in Patients With GIST or Other Solid TumorsRecruitingPhase 1Ascentage Pharma Group Inc.NCT03594422Written as HQP1351
- Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALLRecruitingNot applicableInstitute of Hematology & Blood Diseases Hospital, ChinaNCT06481228Written as Olverembatinib
- Pharmacokinetics of Olverembatinib in Participants With Hepatic ImpairmentRecruitingPhase 1Ascentage Pharma Group Inc.NCT07282093Written as Olverembatinib 20mg
- Newly-diagnosed Pediatric Ph-positive B-ALL ProtocolRecruitingPhase 3Institute of Hematology & Blood Diseases Hospital, ChinaNCT07152041Written as olverembatinib
- Olverembatinib Combined With Venetoclax and Azacitidine in Blast Phase Ph Chromosome-positive CMLRecruitingPhase 1/2Institute of Hematology & Blood Diseases Hospital, ChinaNCT06757855Written as Olverembatinib
- Venetoclax Combined With Olverembatinib and Predinisone in Treating Ph+ B-ALLRecruitingPhase 2First Affiliated Hospital of Zhejiang UniversityNCT06754267Written as Olverembatinib
- A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALLRecruitingPhase 2Nanfang Hospital, Southern Medical UniversityNCT06220487Written as Prednisone, Olverembatinib, Blinatumomab, Chidamide
- Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic LeukemiaRecruitingPhase 1/2Xijing HospitalNCT06082934Written as Olverembatinib plus venetoclax and dexamethasone
- A Study of Olverembatinib Combined With Blinatumomab in the Treatment of Ph+ ALLNot yet recruitingPhase 2The First Affiliated Hospital of Soochow UniversityNCT05931757Written as Olverembatinib
- Olverembatinib for FGFR1-rearranged NeoplasmsRecruitingPhase 2The First Affiliated Hospital of Soochow UniversityNCT05521204Written as Olverembatinib
- Olverembatinib Combined With Reduced-Intensity Chemotherapy and Venetoclax for de Novo Ph+ ALLCompletedPhase 2Institute of Hematology & Blood Diseases Hospital, ChinaNCT05594784Written as Olverembatinib
- A Pivotal Study of HQP1351 in Patients With Chronic Myeloid Leukemia in Chronic PhaseCompletedPhase 2Ascentage Pharma Group Inc.NCT04126681Written as HQP1351
See all 27 studies that test olverembatinib →
Given in every arm · 4 — olverembatinib is usual care beside what is tested
- Study of Olverembatinib (HQP1351) in Patients With CML-CPRecruitingPhase 3Ascentage Pharma Group Inc.NCT06423911Written as olverembatinib
- Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALLRecruitingNot applicableInstitute of Hematology & Blood Diseases Hospital, ChinaNCT07493161Written as Olverembatinib
- ABL/JAK Inhibitors With Chemotherapy and Venetoclax for Ph-like ALLRecruitingNot applicableInstitute of Hematology & Blood Diseases Hospital, ChinaNCT07454226Written as Olverembatinib
- Study of Lisaftoclax (APG-2575) Single Agent and Combination With Therapy in Patients Relapsed/Refractory AMLRecruitingPhase 1/2Ascentage Pharma Group Inc.NCT04501120Written as olverembatinib
Codes
What other systems call olverembatinib · ClinicalTrials.gg INT006263
- MeSH (NLM) C579813olverembatinibConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) KV1M7Q3CBPOLVEREMBATINIBConfirmed FDA, NLM, Wikidata
- Wikidata Q123846205olverembatinibConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C165549OlverembatinibOne source FDA
- DrugBank DB16185One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C579813 | olverembatinib | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | KV1M7Q3CBP | OLVEREMBATINIB | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q123846205 | olverembatinib | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C165549 | Olverembatinib | One source FDA |
| DrugBank | DB16185 | — | One source Wikidata |
Also registered as olverembatinib dimesylate (UNII NPJ9AW8AZR).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.