Obeticholic acid: all 35 studies that test it

Page 1 of 1. Open to participants first (2), then studies with results posted, then the rest; newest registration first within each.

• Obeticholic Acid Among Chronic HBV Patients with Hepatic Steatosis : Clinical and Portal Doppler OutcomesNot yet recruitingNCT06691412Phase 3
• Obeticholic Acid for Prevention in Barrett's EsophagusRecruitingNCT04939051Phase 2
• Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomyTerminatedNCT06121375Phase 2/3Results posted
• Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBCCompletedNCT05239468Phase 2Results posted
• Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBCTerminatedNCT04594694Phase 2Results posted
• Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy SubjectsCompletedNCT04053023Phase 1Results posted
• Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic ImpairmentTerminatedNCT03633227Phase 4Results posted
• Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic SteatohepatitisCompletedNCT03439254Phase 3Results posted
• Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) SignalingCompletedNCT02654236Not applicableResults posted
• Combination Obeticholic Acid (OCA) and Statins for Monitoring of Lipids (CONTROL)CompletedNCT02633956Phase 2Results posted
• Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid TreatmentTerminatedNCT02548351Phase 3Results posted
• Phase 2 Study of Obeticholic Acid for Lipodystrophy PatientsCompletedNCT02430077Phase 2Results posted
• Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary CholangitisTerminatedNCT02308111Phase 4Results posted
• Obeticholic Acid (OCA) in Primary Sclerosing Cholangitis (PSC)CompletedNCT02177136Phase 2Results posted
• Trial of Obeticholic Acid in Patients With Moderately Severe Alcoholic Hepatitis (AH)TerminatedNCT02039219Phase 2Results posted
• Phase 2 Study on Effects of Obeticholic Acid (OCA) on Lipoprotein Metabolism in Participants With Primary Biliary CirrhosisCompletedNCT01865812Phase 2Results posted
• Obeticholic Acid in Bile Acid DiarrhoeaCompletedNCT01585025Phase 2Results posted
• Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary CirrhosisCompletedNCT01473524Phase 3Results posted
• The Farnesoid X Receptor (FXR) Ligand Obeticholic Acid in NASH Treatment Trial(FLINT)CompletedNCT01265498Phase 2Results posted
• Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)CompletedNCT00570765Phase 2Results posted
• Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)TerminatedNCT00550862Phase 2Results posted
• Study of INT-747 in Patients With Diabetes and Presumed NAFLDCompletedNCT00501592Phase 2Results posted
• Comparison of Effectiveness of Obeticholic Acid With Vitamin E in Patients of Non-alcoholic Fatty Liver DiseaseCompletedNCT07104786Phase 2
• Obeticholic Acid Versus Placebo, in Combination with Ursodeoxycholic Acid in Patients with Primary Biliary CirrhosisCompletedNCT06715319Phase 3
• The Effect of Obeticholic Acid in Healthy VolunteersStatus unknownNCT05740631Not applicable
• Comparative Study Between Obeticholic Acid Versus Vitamin E in Patients with Non-alcoholic SteatohepatitisActive, not recruitingNCT05573204Phase 2
• Testing Obeticholic Acid for Familial Adenomatous PolyposisTerminatedNCT05223036Phase 2
• Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult ParticipantsCompletedNCT05133830Phase 1
• Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)Status unknownNCT04956328Phase 3
• Role of Obeticholic Acid in the Patients of NAFLD With Raised ALTCompletedNCT03836937Not applicable
• Effect of Obeticholic Acid on Transport of Bile Acids in PBC Examined by 11C-cholyl-sarcosine PET/CTCompletedNCT03253276Early Phase 1
• Obeticholic Acid in Morbidly Obese Patients and Healthy VolunteersStatus unknownNCT02532335Phase 1
• Single Dose and Multiple Dose Trial to Assess Pharmacokinetics of Obeticholic Acid (OCA)CompletedNCT01933503Phase 1
• Hepatic Impairment Trial of Obeticholic AcidCompletedNCT01904539Phase 1
• Obeticholic Acid in Bariatric and Gallstone DiseaseCompletedNCT01625026Phase 2

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