NUC-1031 clinical trials
Also written NUC-1031, Acelarin and fosgemcitabine palabenamide.
How each study uses NUC-1031 is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
6 studies that test it; most in 2012 (1)
| Year | Studies |
|---|---|
| 2012 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2019 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 6
NuCana plc (2) · Imperial College London (1) · The Christie NHS Foundation Trust (1) · Imperial College Healthcare NHS Trust (1) · The Clatterbridge Cancer Centre NHS Foundation Trust (1)
Related medicines
As reviewed, each with the page that says it.
- One of Antimetabolites source
Studies
Open first, then newest update. How each study uses NUC-1031 is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 6
- NUC-1031 in Patients With Advanced Solid TumoursCompletedPhase 1Imperial College LondonNCT01621854Written as NUC-1031
- Comparing NUC-1031 Plus Cisplatin to Gemcitabine Plus Cisplatin in Patients With Advanced Biliary Tract CancerTerminatedPhase 3NuCana plcNCT04163900Written as NUC-1031
- ABC-08: Phase Ib Trial of Acelarin in Combination With Cisplatin in Locally Advanced/ Metastatic Biliary Tract CancersCompletedPhase 1The Christie NHS Foundation TrustNCT02351765Written as Acelarin
- Safety and Efficacy Study of Nuc-1031 and Carboplatin Combination to Treat Recurrent Ovarian CancerCompletedPhase 1Imperial College Healthcare NHS TrustNCT02303912Written as Nuc-1031 and Carboplatin
- NUC-1031 in Patients With Platinum-Resistant Ovarian CancerTerminatedPhase 2NuCana plcNCT03146663Written as NUC-1031 500 mg
- Acelarin First Line Randomised Pancreatic StudySuspendedPhase 2/3The Clatterbridge Cancer Centre NHS Foundation TrustNCT03610100Written as Acelarin