MYK-461: all 24 studies that test it
Page 1 of 1. Open to participants first (3), then studies with results posted, then the rest; newest registration first within each.
- Efficacy and Safety of an LVEF-Guided Mavacamten Dose Up-Titration Strategy in Chinese Patients With Symptomatic Obstructive Hypertrophic CardiomyopathyNot yet recruitingNCT07807384Phase 4
- Positron Emission Tomography to Assess the Effect of Camzyos on Ischaemia in HOCM: PEACH TrialRecruitingNCT07120776Not applicable
- The Therapeutic Value of Mavacamten in Hypertrophic Cardiomyopathy With Mid-to-Apical Left Ventricular ObstructionEnrolling by invitationNCT07103655Phase 4
- A Study of Mavacamten in Non-Obstructive Hypertrophic CardiomyopathyTerminatedNCT05582395Phase 3Results posted
- A Study of Mavacamten in Obstructive Hypertrophic CardiomyopathyCompletedNCT05414175Phase 3Results posted
- A Study to Evaluate the Efficacy and Safety of Mavacamten in Chinese Adults With Symptomatic Obstructive HCMCompletedNCT05174416Phase 3Results posted
- Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese SubjectsCompletedNCT05135871Phase 1Results posted
- A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnTCompletedNCT04766892Phase 2Results posted
- A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction TherapyCompletedNCT04349072Phase 3Results posted
- Extension Study of Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic Cardiomyopathy Previously Enrolled in PIONEERCompletedNCT03496168Phase 2Results posted
- Clinical Study to Evaluate Mavacamten (MYK-461) in Adults With Symptomatic Obstructive Hypertrophic CardiomyopathyCompletedNCT03470545Phase 3Results posted
- A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)CompletedNCT03442764Phase 2Results posted
- A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract ObstructionCompletedNCT02842242Phase 2Results posted
- A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)Active, not recruitingNCT07004972Phase 4
- Efficacy of Mavacamten in Patients With Symptomatic Latent Obstructive Hypertrophic CardiomyopathyActive, not recruitingNCT06947590Not applicable
- A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic CardiomyopathyActive, not recruitingNCT06253221Phase 3
- A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic CardiomyopathyActive, not recruitingNCT06112743Phase 4
- A Study to Evaluate the Effects of Mavacamten in Healthy ParticipantsCompletedNCT05719805Phase 1
- A Study to Evaluate the Effects on the Single-Dose Drug Levels of Mavacamten in Healthy ParticipantsCompletedNCT05362045Phase 1
- A Study to Evaluate the Effect of Activated Charcoal With Sorbitol on the Single-dose of Mavacamten in Healthy ParticipantsCompletedNCT05320094Phase 1
- A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCMCompletedNCT03723655Phase 2/3
- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Oral Doses of MYK-461 in Healthy VolunteersCompletedNCT02480296Phase 1
- Single Ascending Dose Study of MYK-461 in Healthy VolunteersCompletedNCT02356289Phase 1
- Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-461CompletedNCT02329184Phase 1