Methenamine hippurate clinical trials
Also written Hiprex.
How each study uses methenamine hippurate is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Approvals
The first approval found in each region, with its record
- United States
- 5 Jul 1967 · UREX · NDA 016151 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
8 studies that test it; most in 2019 (2); 1 more planned to start later
| Year | Studies |
|---|---|
| 2014 | 1 |
| 2016 | 1 |
| 2018 | 1 |
| 2019 | 2 |
| 2021 | 1 |
| 2025 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 9
University of Oslo (1) · TriHealth Inc. (1) · University of Pennsylvania (1) · Endeavor Health (1) · University Hospitals of North Midlands NHS Trust (1) · Women and Infants Hospital of Rhode Island (1) · Atlantic Health System (1) · University of Texas Southwestern Medical Center (1)
Often tested with
Tested in the same studies.
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 3
Studies that test methenamine hippurate.
- Jan 2027Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA InjectionPhase 4 · Women and Infants Hospital of Rhode Island
- Jul 2027Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling As Effective As Antibiotic Prophylaxis?Not applicable · Atlantic Health System
- Aug 2027Vitamin C and Hiprex in rUTIEarly Phase 1 · University Hospitals of North Midlands NHS Trust
Studies
Open first, then newest update. How each study uses methenamine hippurate is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 9
- Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA InjectionRecruitingPhase 4Women and Infants Hospital of Rhode IslandNCT06953271Written as Methenamine Hippurate
- Vitamin C and Hiprex in rUTINot yet recruitingEarly Phase 1University Hospitals of North Midlands NHS TrustNCT06710899Written as Methenamine Hippurate 1g BD
- Is Methenamine Prophylaxis for Urinary Tract Infection After Midurethral Sling As Effective As Antibiotic Prophylaxis?RecruitingNot applicableAtlantic Health SystemNCT06810687Written as Methenamine Hippurate 1g BD
- Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections.TerminatedPhase 4University of Texas Southwestern Medical CenterNCT04709601Written as Hiprex
- The Effect of Methenamine Hippurate to Reduce Antibiotic Prescribing in Elderly Women With Recurrent UTICompletedPhase 4University of OsloNCT04077580Written as Methenamine Hippurate 1000 MG
- Urinary Track Infection Prevention After Urogynecological SurgeryCompletedPhase 2TriHealth Inc.NCT03818321Written as Methenamine Hippurate 1 g tablet
- Methenamine in a Non-antibiotic, Multimodal Approach to UTI PreventionWithdrawnPhase 4Washington University School of MedicineNCT03996057Written as Methenamine Hippurate 1000 MG
- Short-course Methenamine Hippurate for Prevention of Post-operative UTICompletedNot applicableUniversity of PennsylvaniaNCT02358993Written as methenamine hippurate
- Methenamine Hippurate Versus Trimethoprim in the Prevention of Recurrent UTIsCompletedPhase 4Endeavor HealthNCT03077711Written as Methenamine hippurate
Codes
What other systems call methenamine hippurate · ClinicalTrials.gg INT002526
- MeSH (NLM) C011481methenamine hippurateConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) M329791L57METHENAMINE HIPPURATEConfirmed FDA, NLM, Wikidata
- RxNorm 29652Confirmed FDA, Wikidata
- Wikidata Q27283414methenamine hippurateConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C47610Methenamine HippurateOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C011481 | methenamine hippurate | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | M329791L57 | METHENAMINE HIPPURATE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 29652 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27283414 | methenamine hippurate | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C47610 | Methenamine Hippurate | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.