Irinotecan: all 829 studies that test it
Page 5 of 9. Open to participants first (121), then studies with results posted, then the rest; newest registration first within each.
- A Study of PEP02 in Combination With 5-fluorouracil (5-FU) and Leucovorin (LV) in Advanced Solid TumorsCompletedNCT02884128Phase 1
- Apatinib and Irinotecan in Treating Patients With Recurrent High-grade GliomaStatus unknownNCT02848794Phase 1/2
- Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors With Sorafenib in Combination With IrinotecanWithdrawnNCT02747537Phase 2
- Irinotecan and Capecitabine as Second-line Treatment for Advanced/Metastatic Biliary Tract CancersWithdrawnNCT02720601Phase 2
- Phase II of BAX2398/5-FU/Calcium Levofolinate in Pancreatic CancerCompletedNCT02697058Phase 2
- Neoadjuvant Triplet Chemotherapy Regimen in Patients With Resectable Colorectal CancerStatus unknownNCT02688023Phase 2
- Irinotecan as 3rd Line Therapy in Gastric CancerStatus unknownNCT02662959Phase 2
- Apatinib and Irinotecan Combination Treatment in Esophageal Squamous Cell CarcinomaCompletedNCT02645864Phase 1
- A Dose Escalation Study of MM-398 Plus Irinotecan in Patients With Unresectable Advanced CancerCompletedNCT02640365Phase 1
- Liposomal Irinotecan and Veliparib in Treating Patients With Solid TumorsCompletedNCT02631733Phase 1
- Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid TumorsCompletedNCT02611024Phase 1/2
- Trial of Capecitabine With or Without Irinotecan Driven by UGT1A1CompletedNCT02605265Phase 3
- Prospective Pilot Trial to Assess a Multimodal Molecular Targeted Therapy in Children, Adolescent and Young Adults With Relapsed or Refractory High-grade PineoblastomaCompletedNCT02596828Phase 2
- A Study of Eribulin in Combination With Oral Irinotecan for Adolescent and Young Adult Patients With Relapsed or Refractory Solid TumorsCompletedNCT02596503Phase 1
- M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryActive, not recruitingNCT02595931Phase 1
- Irinotecan Hydrochloride With FOLFIRI and Cetuximab as First-Line Therapy in Treating Patients With RAS Wild-Type Colorectal CancerWithdrawnNCT02573220Phase 1
- A Randomized Phase III Trial Comparing Folfirinox to Gemcitabine in Locally Advanced Pancreatic CarcinomaCompletedNCT02539537Phase 3
- Study of Oxaliplatin, Irinotecan, and S-1 in Biliary Tract CancerStatus unknownNCT02527824Phase 2
- Study of Oxaliplatin, Irinotecan, and S-1 in Gastric CancerCompletedNCT02527785Phase 2
- Irinotecan Plus Thalidomide in Second Line Advanced Gastric CancerStatus unknownNCT02401971Phase 4
- Pharmacokinetics Study of Nimotuzumab in Patients With Solid TumorsCompletedNCT02395068Phase 1
- A Trial Assessing Several Schedules of Oral S-1 in Combination With a Fixed Dose of Oxaliplatin and IrinotecanCompletedNCT02387138Phase 1
- OXIRI [Oxaliplatin (O), Xeloda (X) and Irinotecan (I)] in Pancreatic AdenocarcinomaCompletedNCT02368860Phase 1
- Genetic Analysis-Guided Irinotecan Hydrochloride Dosing of mFOLFIRINOX in Treating Patients With Locally Advanced Gastroesophageal or Stomach CancerSuspendedNCT02366819Phase 4
- Irinotecan Plus Cisplatin Compared With Etoposide Plus Cisplatin for Extensive Stage Small-cell Lung CancerStatus unknownNCT02348450Phase 4
- Genetic Analysis-Guided Dosing of FOLFIRABRAX in Treating Patients With Advanced Gastrointestinal CancerCompletedNCT02333188Phase 1
- Phase II Study of Irinotecan and Cisplatin in Extensive-stage Small Cell Lung CancerCompletedNCT02323737Phase 2
- Irinotecan Plus S1 Versus S1 in Patients With Previously Treated Advanced Esophageal Cancer: ESWN 01 TrialStatus unknownNCT02319187Phase 3
- Rechallenge of Cetuximab Combined With Irinotecan as Third-line Chemotherapy in Patients With Metastatic Colorectal Cancer - Phase II StudyTerminatedNCT02316496Phase 2
- Activity Study of Bevacizumab With Temozolomide ± Irinotecan for Neuroblastoma in ChildrenCompletedNCT02308527Phase 2
- Cetuximab Rechallenge in Irinotecan-pretreated mCRC, KRAS, NRAS and BRAF Wild-type Treated in 1st Line With Anti-EGFR Therapy (CRICKET).Status unknownNCT02296203Phase 2
- Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal EsophagusTerminatedNCT02283359Phase 1
- Cisplatin/Irinotecan With Concurrent Radiation for Inoperable NSCLCTerminatedNCT02275806Phase 2
- Randomized Multicenter Phase II/III Study With Adjuvant Gemcitabine Versus Neoadjuvant / Adjuvant FOLFIRINOX for Resectable Pancreas CarcinomaCompletedNCT02172976Phase 2/3
- Study of Different Doses of Irinotecan and Cisplatin for First-line Extensive-stage Small-cell Lung Cancer TreatmentStatus unknownNCT02171325Phase 2
- Perioperative FOLFIRI VS Adjuvant FOLFIRI in Resectable Advanced CRC Failed to OxaliplatinStatus unknownNCT02087475Phase 3
- PERIOPERATIVE TREATMENT WITH COI-B (CAPECITABINE, OXALIPLATIN, IRINOTECAN AND BEVACIZUMAB) OF HIGH RISK OR BORDERLINE RESECTABLE COLORECTAL CANCER LIVER METASTASESCompletedNCT02086656Phase 2
- Efficacy and Tolerance of Maintenance Therapy in Patients With Incurable Advanced Colorectal CancerStatus unknownNCT02071069Phase 2
- Genetically Modified Stem Cells and Irinotecan Hydrochloride in Treating Patients With Recurrent High-Grade GliomasWithdrawnNCT02055196Phase 1
- PARP Inhibitor BMN-673 and Temozolomide or Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic Solid TumorsCompletedNCT02049593Phase 1
- Phase II Study of Zaltrap and Chemotherapy for Advanced Resectable Colorectal CancerWithdrawnNCT02046538Phase 2
- ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing SarcomaCompletedNCT02044120Phase 1
- A Phase II Study of Irinotecan in 3 Line or More Therapy in Local Recurrence or Metastatic Breast CancerStatus unknownNCT02030678Phase 2
- Study of Convection-Enhanced, Image-Assisted Delivery of Liposomal-Irinotecan In Recurrent High Grade GliomaCompletedNCT02022644Phase 1
- Evaluation of FDOPA-PET/MRI in Pediatric Patients With CNS TumorsCompletedNCT01999270Phase 1
- Borderline Pancreas Study: FOLFIRINOX +SBRTCompletedNCT01992705Early Phase 1
- Two Different Dosages of Irinotecan Combined With Cisplatin Scheme in Extensive Disease-Small Cell Lung CancerStatus unknownNCT01977235Phase 2
- Individualization of Dosage of Irinotecan in the FOLFIRI According to the Genetic Polymorphism of UGT1A1 in the First Line Treatment of Metastatic Colorectal CancerCompletedNCT01963182Phase 2
- A Pilot Study of Irinotecan in Patients With Breast Cancer and CNS MetastasesWithdrawnNCT01939483Not applicable
- Metformin Plus Irinotecan for Refractory Colorectal CancerStatus unknownNCT01930864Phase 2
- A Phase I Study of Aflibercept Plus FOLFIRI (Irinotecan, 5-Fluorouracil, and Leucovorin) in Chinese Patients With Advanced Solid MalignanciesCompletedNCT01930552Phase 1
- Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal CancerCompletedNCT01923337Phase 1
- A Phase I Study of TAS-102 in Patients With Advanced Gastrointestinal Tumors.CompletedNCT01916447Phase 1
- Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified ChemotherapyActive, not recruitingNCT01871766Phase 2
- Irinotecan and Temozolomide in Combination With Existing High Dose Alkylator Based Chemotherapy for Treatment of Patients With Newly Diagnosed Ewing SarcomaActive, not recruitingNCT01864109Phase 2
- Effect of Curcumin on Dose Limiting Toxicity and Pharmacokinetics of Irinotecan in Patients With Solid TumorsCompletedNCT01859858Phase 1
- GAMBIT Trial: Cisplatin Plus Irinotecan in the Treatment of Gallbladder or Biliary Tract CancerStatus unknownNCT01859728Phase 2
- Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Treatment Combining Cetuximab With FOLFOX or FOLFIRI in RAS and B-RAF WT TumorsTerminatedNCT01858662Phase 2
- Study Comparing Pathological Responses Observed on Colorectal Cancer Metastases Resected After Preoperative Bevacizumab With FOLFOX or FOLFIRI.CompletedNCT01858649Phase 2
- Evaluation of Low-dose Irinotecan and Cyberknife® SBRT to Treat Colorectal Cancer With Limited Liver MetastasisWithdrawnNCT01847495Not applicable
- Standard and High Dose Irinotecan Based on UGT1A1 Genotype for First-line Treatment of Locally Advanced Colon CancerStatus unknownNCT01826396Phase 2
- Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by SurgeryCompletedNCT01787500Phase 1
- Neoadjuvant CAPOXIRI Chemotherapy in the Treatment of Pancreatic Adenocarcinoma ProtocolTerminatedNCT01760252Phase 2
- S-1, Oxaliplatin, and Irinotecan for Advanced Gastrointestinal CancerCompletedNCT01693445Phase 1
- A Protocol of Irinotecan for Carcinoma of the LungWithdrawnNCT01654081Phase 2
- Genotype-guided Dosing of mFOLFIRINOX Chemotherapy in Patients With Previously Untreated Advanced Gastrointestinal MalignanciesCompletedNCT01643499Phase 1
- Intergroup Trial of Adjuvant Chemotherapy in Adenocarcinoma of the StomachCompletedNCT01640782Phase 3
- Study of Relationship Between UGT1A1 Gene Polymorphism and Toxicity and Efficacy of Irinotecan in Small Cell Lung CancerStatus unknownNCT01635400Phase 2
- Chemoembolisation With CPT11 Loaded DC Bead With Cetuximab and 5FU/LV in First Line in Patients With KRAS Wildtype mCRCWithdrawnNCT01631539Not applicable
- FOLFIRI or mFOLFOX6 in Adjuvant Chemotherapy in Advanced Colorectal CancerStatus unknownNCT01566942Phase 3
- Xeloxiri as First-line Treatment in Patients With Advanced Unresectable Pancreatic AdenocarcinomaCompletedNCT01558869Phase 2
- Metformin in Children With Relapsed or Refractory Solid TumorsCompletedNCT01528046Phase 1
- Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer PatientsCompletedNCT01523431Phase 2/3
- Safety Study of the Drug MM-151 in Patients With Advanced Solid Tumors Resisting Ordinary TreatmentCompletedNCT01520389Phase 1
- Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients With Solid TumorsCompletedNCT01518413Phase 1
- Irinotecan/Capecitabine Versus Capecitabine in Patients Treated With A/T for HER2 Negative Metastatic Breast CancerStatus unknownNCT01501669Phase 3
- Phase II Study of FOLFOXIRI in Patients With Locally Advanced or Metastatic Biliary Tract CancerStatus unknownNCT01494363Phase 2
- LDE225 With Fluorouracil, Leucovorin, Oxaliplatin, and Irinotecan for Untreated Advanced Pancreatic CancerCompletedNCT01485744Phase 1
- Genotype-driven Phase I Study of Irinotecan Administered in Neoadjuvant Chemoradiotherapy in Patients With Stage II/III Rectal CancerStatus unknownNCT01474187Phase 1
- Genotype-drive Study of Irinotecan-Cisplatin Combination for Advanced Gastric CancerCompletedNCT01444521Phase 2
- Chemotherapies Associated With Targeted Therapies on the Resection Rate of Hepatic MetastasesCompletedNCT01442935Phase 2
- Individualized Chemotherapy Based on BRCA1 and RRM1 mRNA for Advanced Non-small Cell Lung Cancer (NSCLC)Status unknownNCT01424709Phase 2
- Chemotherapy for Patients With Locally Advanced Pancreatic Cancer (LAPC) With Additional Chemo-radiotherapy (CRT) for Patients With Borderline Resectable TumoursCompletedNCT01397019Phase 2
- Sorafenib Tosylate, Bevacizumab, Irinotecan Hydrochloride, Leucovorin Calcium, and Fluorouracil in Treating Patients With Metastatic Colorectal CancerCompletedNCT01383343Phase 1
- Trial of Docetaxel and Irinotecan (DI) for Recurrent or Refractory Bone and Soft Tissue Sarcomas.Status unknownNCT01380275Phase 2
- Vincristine and Irinotecan With or Without Temozolomide in Children and Adults With Refractory/Relapsed RhabdomyosarcomaCompletedNCT01355445Phase 2
- Safety and Pharmacokinetics of Treating Liver Cancer With Drug-Eluting BeadsTerminatedNCT01336985Phase 1
- Study of Irinotecan Plus Capecitabine to Treat Advanced Colorectal CancerCompletedNCT01322152Phase 2
- Metronomic Temozolamide in Patients With Recurrent GlioblastomaStatus unknownNCT01308632Phase 2/3
- IXO+A in mCRC With Liver-only MetastasesWithdrawnNCT01293942Phase 2
- Simvastatin + Cetuximab/Irinotecan in K-ras Mutant Colorectal Cancer (CRC)CompletedNCT01281761Phase 2
- Study of REOLYSIN® in Combination With FOLFIRI and Bevacizumab in FOLFIRI Naive Patients With KRAS Mutant Metastatic Colorectal CancerCompletedNCT01274624Phase 1
- Investigation of Association Between UGT1A1 Polymorphisms and Irinotecan Toxicity in Korean PatientsStatus unknownNCT01271582Phase 4
- A Study of Neoadjuvant Chemoradiotherapy With 5-FU/Leucovorin (FL) vs. TS-1/Irinotecan in Patients With Locally Advanced Rectal CancerCompletedNCT01269216Phase 2
- Study of IRNEA (Irinotecan, Etoposide, Cytarabine) for Refractory or Relapsed Acute Leukemia in Children and AdolescentsStatus unknownNCT01239485Phase 1
- Study of NK012 and Carboplatin in Solid Tumors With Dose Expansion in Triple Negative Breast CancerCompletedNCT01238952Phase 1
- Study of NK012 and 5-FU/LV in Solid Tumors Followed by Dose Expansion in Colorectal CancerCompletedNCT01238939Phase 1
- Erbitux Study of CPT11, Oxaliplatin, UFToral Targeted TherapyCompletedNCT01225744Phase 2
- Efficacy Study of Paclitaxel Versus Irinotecan in Patients With Recurrent or Metastatic Gastric Cancer Who Progress Following First-line TherapyStatus unknownNCT01224652Phase 3
- RSHF in Colorectal CancerCompletedNCT01220063Phase 2