Combination productDrug
Hydroquinone clinical trials
How each study uses hydroquinone is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- 18 Jan 2002 · TRI-LUMA · NDA 021112 (FDA, Drugs@FDA; in a combination)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Name
- Hydroquinone
- 1
Studies by the year they started
3 studies that test it; most in 2014 (1)
| Year | Studies |
|---|---|
| 2014 | 1 |
| 2022 | 1 |
| 2023 | 1 |
Who runs them
Industry 1 · Other 2
Jinnah Postgraduate Medical Centre (1) · National Skin Centre (1) · Mesoestetic Pharma Group S.L. (1)
Often tested with
Tested in the same studies.
Related medicines
As reviewed, each with the page that says it.
- One of Antioxidants source
Studies
Open first, then newest update. How each study uses hydroquinone is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 3
- Efficacy of Eflornithine Hydrochloride Cream in the Treatment of Melasma: A Randomized, Double-blinded, Split-face Controlled StudyCompletedPhase 2National Skin CentreNCT06957834Written as Hydroquinone cream
- Comparison Of Efficacy Of Combination Of TAM Formula Vs Kligman Formula For Melasma.Active, not recruitingPhase 2Jinnah Postgraduate Medical CentreNCT06013540Written as TAM formula (hydroquinone 2%, tretinoin 0.05% and 5% vitamin C)
- Efficacy and Safety of a 4% Hydroquinone Cream for the Treatment of MelasmaCompletedPhase 3Mesoestetic Pharma Group S.L.NCT02095990Written as Hydroquinone
Given beside what is tested · 2 — hydroquinone is usual care or a partner of the new treatment
- Oral Tranexamic Acid and Topical Hydroquinone in the Treatment of MelasmaCompletedPhase 3Fakultas Kedokteran Universitas IndonesiaNCT03751163Written as Hydroquinone 4% Cream
- A Comparative Study for Efficacy and Safety Between 4% Hydroquinone Cream With or Without Fractional Picosecond 1,064 nm Laser for the Treatment of Dermal or Mixed Type MelasmaCompletedPhase 2Mae Fah Luang University HospitalNCT03049059Written as 4% hydroquinone cream
As the comparator · 14 — what is tested is compared with hydroquinone
- Prospective Evaluation of Topical Almond Oil vs HydroquinoneRecruitingPhase 4University of California, DavisNCT04875715Written as Hydroquinone Topical
- Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPESNot yet recruitingNot applicableDr.dr.Irma Bernadette, SpKK (K)NCT07121439Written as 2% hydroquinone cream
- Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of MelasmaCompletedPhase 4Pak Emirates Military HospitalNCT07508098Written as Hydroquinone 4% Cream
- Comparison of Efficacy of Metformin Gel 30% vs Triple Combination Cream (Hydroquinone 4%, Flucinolone Acetonide 0.01%, Tretinoin 0.025%) in Treatment of Melasma in Tertiary Care Hospital KarachiCompletedNot applicableJinnah Postgraduate Medical CentreNCT07345507Written as Triple combination cream (hydroquinone 2% + tretinoin 0.025% + fluocinolone acetonide 0.01%)
- A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee OsteoarthritisCompletedNot applicableNPO PetrovaxNCT06032442Written as Artra
- EFFICACY and TOLERABILITY of TESTED FORMULA VS. HYDROQUINONE 4% in the TREATMENT of FACIAL MELASMACompletedNot applicableCosmetique Active InternationalNCT06787846Written as Active Comparator: Group HQ: Hydroquinone 4%
- Randomized and Open Label Study for Safety and Efficacy of DBI-102 vs. Vehicle vs. Hydroquinone on Skin Pigmentation and LentigosCompletedPhase 2DermBiont, Inc.NCT05511948Written as Hydroquinone Cream
- Cysteamine Compared to Hydroquinone in MelasmaCompletedPhase 3China Medical University HospitalNCT05969587Written as hydroquinone cream group
- A Clinical Study to Evaluate the Effect of Facial Serum Q69 in Moderating the Appearance of Mild to Moderate MelasmaCompletedNot applicableUnilever R&DNCT05013801Written as 2% Hydroquinone
- Comparison of Topical Silymarin With Hydroquinone in the Treatment of MelasmaCompletedPhase 2Islamabad Medical and Dental CollegeNCT03982849Written as Hydroquinone 4% Cream
- Oral and Topical Tranexamic Acid for the Treatment of MelasmaStatus unknownPhase 3Centro Dermatológico Dr. Ladislao de la PascuaNCT03585179Written as 4% hydroquinone
- Evaluation of an Herbal-Based De-Pigmenting SystemCompletedPhase 4Sadick Research GroupNCT02138539Written as Hydroquinone
- Clinical Trial of Hydroquinone Versus Miconazol in MelasmaStatus unknownPhase 4Universidad Autonoma de San Luis PotosíNCT01661556Written as Hydroquinone
- Azelaic Acid Versus Hydroquinone in MelasmaStatus unknownPhase 4Callender Center for Clinical ResearchNCT00927771Written as hydroquinone cream
Codes
What other systems call hydroquinone · ClinicalTrials.gg INT002966
- MeSH (NLM) C031927hydroquinoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) XV74C1N1AEHYDROQUINONEConfirmed FDA, NLM, Wikidata
- RxNorm 5509Confirmed FDA, Wikidata
- Wikidata Q419164hydroquinoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29823HydroquinoneOne source FDA
- DrugBank DB09526One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C031927 | hydroquinone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | XV74C1N1AE | HYDROQUINONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5509 | — | Confirmed FDA, Wikidata |
| Wikidata | Q419164 | hydroquinone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29823 | Hydroquinone | One source FDA |
| DrugBank | DB09526 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.