DrugBiological
Four-factor Prothrombin Complex Concentrate clinical trials
Keep track of what changes. Save the Four-factor Prothrombin Complex Concentrate studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
9 studies that test it; most in 2008 (1)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2009 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2020 | 1 |
| 2023 | 1 |
| 2025 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 5 · Other 4
CSL Behring (4) · Janssen Research & Development, LLC (1) · HealthPartners Institute (1) · Thomas Jefferson University (1) · University of Maryland, Baltimore (1) · University of Utah (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses Four-factor Prothrombin Complex Concentrate is read from its arms, and is right about nine times in ten.
Testing it · 9
- Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)RecruitingPhase 3CSL BehringNCT07094087Written as BE1116
- Evaluation of BE1116 in Patients With Traumatic Injury and Acute Major Bleeding to Improve Survival ( TAP Study )TerminatedPhase 3CSL BehringNCT05568888Written as BE1116
- A Study to Assess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy ParticipantsCompletedPhase 1Janssen Research & Development, LLCNCT04543383Written as 4-Factor Prothrombin Complex Concentrate (4F-PCC)
- Administration of Prothrombin Complex Concentrate vs. Standard Transfusion During/After Heart TransplantationTerminatedPhase 3University of Maryland, BaltimoreNCT03341156Written as Kcentra
- Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin ReversalCompletedPhase 4HealthPartners InstituteNCT03064035Written as 4-factor prothrombin complex concentrate (4FPCC)
- FFP Versus PCC in Intracranial HemorrhageWithdrawnNot applicableUniversity of UtahNCT02429453Written as Four Factor Prothrombin Complex Concentrate
- Reversibility of Apixaban Anticoagulation With the Four Factor Prothrombin Complex Concentrate KcentraCompletedPhase 1Thomas Jefferson UniversityNCT02270918Written as Kcentra
- An Open-label, Randomized, Multicenter Phase IIIb Study to Assess the Efficacy, Safety and Tolerance of BERIPLEX® P/N (Kcentra) Compared With Plasma for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Subjects Requiring an Urgent Surgical ProcedureCompletedPhase 3CSL BehringNCT00803101Written as Beriplex® P/N (Kcentra)
- Efficacy and Safety Study of BERIPLEX® P/N (Kcentra) Compared With Plasma in Patients With Acute Major Bleeding Caused by Anticoagulant TherapyCompletedPhase 3CSL BehringNCT00708435Written as Beriplex® P/N (Kcentra)