Fostamatinib: all 53 studies that test it

Page 1 of 1. Open to participants first (5), then studies with results posted, then the rest; newest registration first within each.

• Syk Inhibition in MItigating Lung Allograft Rejection (SIMILAR): A Trial to Evaluate the Safety and Tolerability of Fostamatinib in Lung Transplant Patients With Donor-Specific AntibodiesRecruitingNCT06948097Phase 1
• Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized AdultsNot yet recruitingNCT06564207Phase 2
• Ruxolitinib Plus Fostamatinib for Steroid Refractory cGvHDRecruitingNCT06233110Phase 1
• Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseRecruitingNCT05904093Phase 1
• A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic AnemiaEnrolling by invitationNCT04138927Phase 3
• International Sites: Novel Experimental COVID-19 Therapies Affecting Host ResponseTerminatedNCT05593770Phase 2/3Results posted
• Using Fostamatinib to Treat Post-Hematopoietic Stem Cell Transplant Immune-mediated CytopeniasTerminatedNCT05502783Phase 2Results posted
• Novel Experimental COVID-19 Therapies Affecting Host ResponseCompletedNCT04924660Phase 2/3Results posted
• Fostamatinib for Hospitalized Adults With COVID-19CompletedNCT04579393Phase 2Results posted
• A Clinical Study in Patients With Chronic Idiopathic Thrombocytopenic Purpura in R788CompletedNCT04132050Phase 3Results posted
• A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHACompletedNCT03764618Phase 3Results posted
• Clinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian CancerCompletedNCT03246074Phase 1Results posted
• Safety and Efficacy Study of Fostamatinib to Treat Immunoglobin A (IgA) NephropathyCompletedNCT02112838Phase 2Results posted
• Randomised Double-Blind, Placebo-Controlled, Parallel Group Study in Patients With Active Rheumatoid Arthritis:Magnetic Resonance Imaging Sub-StudyTerminatedNCT02092961Phase 2Results posted
• Open Label Study of R788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)CompletedNCT02077192Phase 3Results posted
• A Efficacy and Safety Study of Fostamatinib in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)CompletedNCT02076412Phase 3Results posted
• A Efficacy and Safety Study of R935788 in the Treatment of Persistent/Chronic Immune Thrombocytopenic Purpura (ITP)CompletedNCT02076399Phase 3Results posted
• A Long Term Study to Assess the Safety of Fostamatinib in Patients in Asia With Rheumatoid ArthritisTerminatedNCT01640054Phase 2Results posted
• Evaluation of Safety and Effectiveness of Fostamatinib Compared to Placebo in Patients in Asia With Rheumatoid ArthritisTerminatedNCT01569074Phase 2Results posted
• Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid ArthritisCompletedNCT01563978Phase 2Results posted
• Study to Learn if 200mg Test Drug (Fostamatinib) Helps People With Large B-Cell Lymphoma,a Type of Blood CancerCompletedNCT01499303Phase 2Results posted
• Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)TerminatedNCT01242514Phase 3Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate and Have Had Inadequate Response to Single TNF-alpha AntagonistCompletedNCT01197755Phase 3Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Disease Modifying Anti-rheumatic Drug (DMARD) But Not Responding.CompletedNCT01197534Phase 3Results posted
• Evaluation of Effectiveness of Two Dosing Regimens of Fostamatinib Compared to Placebo in Patients With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Not Responding.CompletedNCT01197521Phase 3Results posted
• A Broad Multi-histology Phase II Study of the Multi-Kinase Inhibitor R935788 (Fostamatinib Disodium) in Advanced Colorectal, Non-small Cell Lung, Head and Neck Hepatocellular and Renal Cell Carcinomas, and Pheochromocytoma and Thyroid Tumors (Multi-H...CompletedNCT00923481Phase 2Results posted
• Open-Label, Multicenter Extension Study for Patients Completing Treatment Phase of a Rigel-Sponsored R935788 StudiesTerminatedNCT00805467Phase 2Results posted
• Efficacy and Safety Study of Fostamatinib Disodium Tablets to Treat T-Cell LymphomaCompletedNCT00798096Phase 2Results posted
• Pilot Study of Fostamatinib Disodium/R935788 for the Treatment of Adult Refractory Immune Thrombocytopenic Purpura (ITP)CompletedNCT00706342Phase 2Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid ArthritisCompletedNCT00665925Phase 2Results posted
• Efficacy and Safety Study of R935788 Tablets to Treat Rheumatoid Arthritis (Taski-3)CompletedNCT00665626Phase 2Results posted
• Efficacy and Safety Study of Fostamatinib Tablets to Treat B-cell LymphomaCompletedNCT00446095Phase 1/2Results posted
• Extension Study (Extended Access) of Syk-inhibition Using Fostamatinib to Treat Posttransplant Immune-mediated CytopeniasWithdrawnNCT05509582Phase 2
• Study of the Effect of Fostamatinib Upon Cutaneous Inflammation in the Setting of Hidradenitis SuppurativaCompletedNCT05040698Phase 2
• Fostamatinib for the Treatment of Lower-risk Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia Who Have Failed Therapy with Hypomethylating AgentsCompletedNCT05030675Phase 1
• Inflammatory Signal Inhibitors for COVID-19 (MATIS)CompletedNCT04581954Phase 1/2
• Fostamatinib in the Treatment of Chronic Active Antibody Mediated RejectionActive, not recruitingNCT03991780Phase 1/2
• A Safety and Efficacy Study of R935788 in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (AIHA)CompletedNCT02612558Phase 2
• Evaluation of Fostamatinib in Patients With cGVHD After Allogeneic Stem Cell TransplantCompletedNCT02611063Phase 1
• Open Label Study of Fostamatinib in the Treatment of IgA NephropathyWithdrawnNCT02433236Phase 2
• Assess the Pharmacokinetics of Rosuvastatin and Simvastatin When Administered Alone or in Combination With FostamatinibCompletedNCT01725230Phase 1
• A Single and Multiple Dose Study to Assess Blood and Urine Drug Levels of Fostamatinib in Healthy Japanese SubjectsCompletedNCT01608542Phase 1
• Study in Healthy Males to Assess Bioavailability of Single Fostamatinib With iv Micro Tracer DoseCompletedNCT01598571Phase 1
• Study in Healthy Males to Assess the Bioavailability of 4 Different Fostamatinib TabletsCompletedNCT01387308Phase 1
• Effects of Administration of Fostamatinib on Blood Concentrations of Digoxin in Healthy SubjectsCompletedNCT01355354Phase 1
• Effects of Administration of Fostamatinib on Blood Concentrations of Warfarin in Healthy SubjectsCompletedNCT01311622Phase 1
• Effects of Administration of Fostamatinib on Blood Concentrations of Pioglitazone in Healthy SubjectsCompletedNCT01309854Phase 1
• Effects of Administration of Fostamatinib on Blood Concentrations of an Oral Contraceptive in Healthy Female SubjectsCompletedNCT01276262Phase 1
• A Study of Fostamatinib in Subjects With Impaired Kidney FunctionCompletedNCT01245790Phase 1
• A Study of Fostamatinib in Subjects With Impaired Hepatic (Liver) FunctionCompletedNCT01222455Phase 1
• Study in Healthy Males to Assess Bioavailability of 4 Different Fostamatinib TabletsCompletedNCT01208155Phase 1
• Efficacy and Safety Study of R935788 Tablets to Treat Systemic Lupus ErythematosusWithdrawnNCT00752999Phase 2
• Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)CompletedNCT00326339Phase 2

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