Fibrinolytic Agents: all 366 studies that test it
Page 3 of 4. Open to participants first (56), then studies with results posted, then the rest; newest registration first within each.
- Tenecteplase Versus Alteplase for Stroke Thrombolysis Evaluation Trial in the AmbulanceCompletedNCT04071613Phase 2
- A PhaseⅡ of Injection for Recombinant Human Tissue Plasminogen Kinase Derivative in Treatment of Acute Ischemic Stroke.Status unknownNCT04028518Phase 2
- Efficacy and Safety of CUSA-081 in the Restoration of Dysfunctional Central Venous Access Device (CVAD) FunctionalityWithdrawnNCT03992443Phase 3
- Thrombolysis Endovascular Treatment of Pulmonary EmbolismCompletedNCT03966079Phase 3
- Pharmacokinetic and Metabolism of [14^C] BMS-986177 in Healthy Male ParticipantsCompletedNCT03939702Phase 1
- Alteplase Compared to Tenecteplase in Patients With Acute Ischemic StrokeCompletedNCT03889249Phase 3
- The Norwegian Tenecteplase Stroke Trial 2TerminatedNCT03854500Phase 3
- Low Dose Catheter Directed Thrombolysis for Acute Pulmonary EmbolismStatus unknownNCT03854266Phase 2
- Open-Label, Randomised, Active Controlled, Multi-Centre Phase 3 Study Safety and Efficacy of Danaparoid vs ArgatrobanTerminatedNCT03809481Phase 3
- Defibrotide in Sickle Cell Disease-Related Acute Chest SyndromeCompletedNCT03805581Phase 2
- A Study to Assess Administration of an Oral Anti-thrombotic With Antiplatelet Therapy in Healthy SubjectsCompletedNCT03698513Phase 1
- The Safety and Efficacy of Fibrinolysis in Patients With an Indwelling Pleural Catheter for Multi-loculated Malignant Pleural Effusion.WithdrawnNCT03678090Phase 2
- Intramyocardial Haemorrhage in Patients With Primary STEMICompletedNCT03677466Not applicable
- Study to Determine the Efficacy of Uproleselan (GMI-1271) in Combination With Chemotherapy to Treat Relapsed/Refractory Acute Myeloid LeukemiaTerminatedNCT03616470Phase 3
- A Study in Healthy Volunteers to Investigate How Much Test Medicine [14C]-Uproleselan is Taken up by the Body When Administered Directly Into the Vein (IV)CompletedNCT03606447Phase 1
- Peripheral Systemic Thrombolysis Versus Catheter Directed Thrombolysis for Submassive PEActive, not recruitingNCT03581877Phase 4
- Direct Intra-arterial Thrombectomy in Order to Revascularize AIS Patients With Large Vessel Occlusion Efficiently in Chinese Tertiary HospitalsCompletedNCT03469206Not applicable
- Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDSCompletedNCT03465085Phase 3
- Regisry of the Stroke Patients in Assiut University HospitalStatus unknownNCT03392792Not applicable
- A Study in MPS VI to Assess Safety and Efficacy of OdiparcilCompletedNCT03370653Phase 2
- Evaluate the Pharmacokinetics of BMS-986177 From Two Formulations in Healthy ParticipantsCompletedNCT03362437Phase 1
- Study of Sodium Bicarbonate in Restoring Blocked CathetersWithdrawnNCT03348826Phase 2
- An Investigational Study to Assess the Effect of BMS-986177 on Aspirin in Healthy ParticipantsCompletedNCT03341390Phase 1
- Determining the Optimal Dose of Tenecteplase Before Endovascular Therapy for Ischaemic Stroke (EXTEND-IA TNK Part 2)CompletedNCT03340493Phase 2
- Adjunctive, Low-dose tPA in Primary PCI for STEMICompletedNCT03335839Phase 3
- A Study to Assess the Effect of Ticlopidine on the Pharmacokinetics, Safety, and Tolerability of Intranasally Administered Esketamine in Healthy ParticipantsCompletedNCT03298906Phase 1
- To Evaluate the Safety and Pharmacokinetics of BMS-986177 in Healthy Japanese ParticipantsCompletedNCT03224260Phase 1
- A Phase III Randomized, Blind, Double Dummy, Multicenter Study Assessing the Efficacy and Safety of IV THrombolysis (Alteplase) in Patients With acutE Central retInal Artery OcclusionCompletedNCT03197194Phase 3
- Evaluate Pharmacokinetics and Safety of BMS-986177 in Participants With Normal Renal Function and With Moderate or Severe Renal ImpairmentCompletedNCT03196206Phase 1
- Study of Antithrombotic Treatment After IntraCerebral HaemorrhageTerminatedNCT03186729Phase 4
- Tenecteplase in Wake-up Ischaemic Stroke TrialStatus unknownNCT03181360Phase 3
- Evaluating Different Modalities for Pleural Adhesiolysis at Assuit University HospitalStatus unknownNCT03172052Phase 4
- Weight Adjusted Low Molecular Weight Heparin in Recurrent Implantation Failure: a Randomized Open Labeled TrialTerminatedNCT02991950Phase 3
- Single-dose Pharmacokinetics of BMS-986177 in Participants With Hepatic Impairment Compared to Healthy ParticipantsCompletedNCT02982707Phase 1
- A Study to Evaluate the Effect of Rifampin on the Single-dose Pharmacokinetics of BMS-986177 in Healthy SubjectsCompletedNCT02959060Phase 1
- A Study to Evaluate the Safety and Pharmacokinetics of BMS-986177 in Participants With End-stage Renal Dysfunction on Chronic Stable Hemodialysis TreatmentCompletedNCT02902679Phase 1
- Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot StudyStatus unknownNCT02894138Phase 3
- The Efficacy and Safety of rhTNK-tPA in Comparison With Alteplase(Rt-PA) as Fibrinolytic Therapy of Acute STEMICompletedNCT02835534Phase 4
- Alteplase-Tenecteplase Trial Evaluation for Stroke ThrombolysisCompletedNCT02814409Phase 3
- A Study to Determine the Efficacy, Safety and Pharmacokinetics of GMI-1271 as Adjunct to Standard of Care for the Treatment of Multiple MyelomaCompletedNCT02811822Phase 1
- A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Pharmacokinetics of BMS-986177 in Healthy SubjectsCompletedNCT02807909Phase 1
- Pediatric High-Risk Deep Venous Thrombosis Lytic Outcomes TrialWithdrawnNCT02767232Phase 3
- Study to Assess Safety, Tolerability, and Efficacy of GMI-1271 in Patients With Calf-level Deep Venous Thrombosis (DVT)TerminatedNCT02744833Phase 1/2
- A Study to Evaluate the PK, Safety and Tolerability of GMI-1271 With and Without Filgrastim in Healthy Adult SubjectsCompletedNCT02703051Phase 1
- Safety and Tolerability Study of BMS-986177 in Healthy SubjectsCompletedNCT02608970Phase 1
- Efficacy and Safety of Half Dose Alteplase Added to Heparine, in Patients With Moderate Pulmonary EmbolismWithdrawnNCT02604238Phase 3
- A Phase III Study of KCT-0809 in Dry Eye Patients With Sjögren's SyndromeCompletedNCT02503189Phase 3
- An Extension Study of KCT-0809 in Dry Eye Patients With Sjögren's SyndromeTerminatedNCT02503176Phase 3
- A Long-term Study of KCT-0809 in Dry Eye Patients With Sjögren's SyndromeCompletedNCT02503163Phase 3
- TOP-TRIAL Safety of Not Flushing Non-used PORT-A-CATH® in Cancer PatientsTerminatedNCT02492477Phase 1
- Intensive Versus Standard Hemodialysis CVC Dysfunction ProtocolCompletedNCT02474810Not applicable
- Dose-effect Relationship of Rt-PA on ICH EvacuationStatus unknownNCT02472574Phase 2
- Helping Stroke Patients With ThermoSuit CoolingTerminatedNCT02453373Not applicable
- Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic StrokeCompletedNCT02388061Phase 2
- Superiority of Rt-PA + Tenecteplase in Comparison With Rt-PA Only in Proximal Middle Cerebral Artery OcclusionWithdrawnNCT02338466Phase 2
- A Phase 1 Study of ProMetic Plasminogen (Human) Intravenous in Adults and Children With Plasminogen DeficiencyCompletedNCT02312180Phase 1
- Phase I Study to Assess Safety and Pharmacokinetics of GMI-1271 in Healthy Adult SubjectsCompletedNCT02271113Phase 1
- A Trial of Low-dose Adjunctive alTeplase During prIMary PCICompletedNCT02257294Phase 2
- Trial to Compare 1.0 Versus 2.0 mg Alteplase (tPA) Dosing in Restoring Hemodialysis Catheter FunctionStatus unknownNCT02225782Not applicable
- A Study to Investigate the Procoagulant Effect of Tenecteplase (TNK-tPA), Alteplase (Rt-PA) and Streptokinase (SK) Administered to Patients With Acute Myocardial Infarction (AMI)CompletedNCT02182011Phase 3
- Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN)WithdrawnNCT02180204Phase 2/3
- Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy VolunteersCompletedNCT02168595Phase 1
- Asia Africa Streptokinase TrialWithdrawnNCT02150785Phase 2
- Combination Tissue Plasminogen Activator (Tpa) and Dornase Alfa (Dnase) Administration Through Intrapleural Catheters for the Treatment of Loculated or Non-Draining Malignant Pleural EffusionsStatus unknownNCT02135588Phase 1
- Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary EmbolismCompletedNCT02132689Phase 4
- Penumbral Based Novel Thrombolytic Therapy in Acute Ischemic StrokeCompletedNCT02101606Phase 2
- THrombolysis for Acute Wake-up and Unclear-onset Strokes With Alteplase at 0.6 mg/kg Trial (THAWS)Status unknownNCT02002325Phase 3
- Use of Streptokinase for Enhancement of Percutaneous Drainage of Pancreatic NecrosisCompletedNCT01977118Phase 2/3
- Comparison of Low-Molecular-Weight Heparin (LMWH) and Unfractionated Heparin (UFH) in Combination With Thrombolytic Treatment of Acute Massive Pulmonary ThromboembolismStatus unknownNCT01956955Phase 4
- Study of Tenecteplase Versus Alteplase for Thrombolysis (Clot Dissolving) in Acute Ischemic StrokeCompletedNCT01949948Phase 3
- EARLY Routine Catheterization After Alteplase Fibrinolysis vs. PPCI in ST-Segment-Elevation MYOcardial InfarctionCompletedNCT01930682Phase 4
- A Late Phase II Study of KCT-0809 in Patients With Dry Eye SyndromesCompletedNCT01890941Phase 2
- Effect of Intraventricular tPA Following Aneurysmal Subarachnoid HemorrhageWithdrawnNCT01878136Phase 1/2
- Intravitreal tPA and C3F8 for the Treatment of Submacular Haemorrhage as a Complication of Neovascular AMDCompletedNCT01835067Phase 2/3
- Safety and Efficacy Study of PD-616 Plus Cytarabine to Treat Acute Myelogenous Leukemia or Myelodysplastic SyndromeTerminatedNCT01795924Phase 1/2
- A Parallel Group Phase II Study of KCT-0809 in Patients With Dry Eye SyndromesCompletedNCT01692145Phase 2
- Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PAStatus unknownNCT01670474Phase 4
- Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb IschemiaTerminatedNCT01638585Phase 3
- Efficacy, Safety, and Tolerability of Ancrod in Patients With Sudden Hearing LossCompletedNCT01621256Phase 1/2
- Intra-arterial Thrombolysis for Severe Recent Central Retinal Vein OcclusionCompletedNCT01581411Phase 1
- EXTEND (International): Extending the Time for Thrombolysis in Emergency Neurological Deficits (International)CompletedNCT01580839Phase 3
- Safety and Efficacy of the Use of Tissue Plasminogen Activator (tPA) in Intra-Abdominal Collections in Children - A Prospective StudyTerminatedNCT01576679Phase 3
- Local Thrombolytics Before Thrombectomy in STEMIStatus unknownNCT01568931Phase 4
- Low Dose Rt-PA for Acute Normotensive Pulmonary Embolism With RVDStatus unknownNCT01531829Phase 4
- Efficacy and Safety of MRI-based Thrombolysis in Wake-up StrokeCompletedNCT01525290Phase 3
- The Safety and Tolerability of Intra-abdominal t-PA and DNase on Peritonitis in Peritoneal Dialysis PatientsTerminatedNCT01478698Phase 1
- Alteplase-Tenecteplase Trial Evaluation for Stroke Thrombolysis- (ATTEST)CompletedNCT01472926Phase 2
- Wake up Symptomatic Stroke - Benefit of Intravenous Clot Busters or Endovascular InterventionStatus unknownNCT01455935Phase 2
- Comparison of Different TRansesophageal Echocardiography Guided thrOmbolytic Regimens for prosthetIc vAlve ThrombosisCompletedNCT01451320Not applicable
- Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy SubjectsCompletedNCT01451229Phase 1
- A Phase II Study of KCT-0809 in Patients With Dry Eye SyndromeCompletedNCT01427816Phase 2
- Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED)CompletedNCT01422616Phase 3
- Effect of NCX4016 on Walking Distance in Patients With Peripheral Arterial Occlusive Disease (PAOD)CompletedNCT01256775Phase 2
- Effect of Itraconazole and Ticlopidine on the Pharmacokinetics and Pharmacodynamics of Oral TramadolCompletedNCT01214941Phase 4
- A Study of KCT-0809 in Patients With Dry Eye SyndromesCompletedNCT01211951Phase 2
- Thrombolysis or Anticoagulation for Cerebral Venous ThrombosisTerminatedNCT01204333Phase 2/3
- Study for the Use of Alteplase in Patients Who Awaken With StrokeWithdrawnNCT01150266Phase 1
- Intrapleural Urokinase for Retained HemothoraxStatus unknownNCT01134237Phase 3
- Clinical Study of Desmoteplase in Japanese Patients With Acute Ischemic StrokeCompletedNCT01104467Phase 2
- Intraventricular Tissue Plasminogen Activator (tPA) in the Management of Aneurysmal Subarachnoid HemorrhageStatus unknownNCT01098890Phase 2