Dupilumab: all 174 studies that test it

Page 1 of 2. Open to participants first (33), then studies with results posted, then the rest; newest registration first within each.

• This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring HospitalizationRecruitingNCT07587658Phase 4
• Comparison of Eohilia With Dupixent on Esophagus Diameter in Patients With Eosinophilic Esophagitis.Enrolling by invitationNCT07358234Early Phase 1
• Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
• A Study to Evaluate Efficacy and Safety of IBI356 in Participants With Moderate to Severe Atopic DermatitisRecruitingNCT07330934Phase 2
• Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver MetastasesRecruitingNCT07277322Phase 1/2
• A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic EsophagitisRecruitingNCT07112378Phase 3
• Dupilumab Therapy in Nephrotic Syndrome in ChildrenRecruitingNCT07091175Phase 2
• A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.RecruitingNCT07053423Phase 4
• Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung CancerRecruitingNCT06743581Not applicable
• Dupilumab Versus Topical Corticosteroid Effectiveness - Comparison in the Treatment of Stenotic EoERecruitingNCT06705387Phase 2
• Effect of Dupilumab on the Muscle Function of the Esophagus (food Pipe) in Participants with Eosinophilic Esophagitis (EoE)RecruitingNCT06665971Phase 4
• Neoadjuvant Dupilumab, Pembrolizumab, Paclitaxel, and Carboplatin in Locally Advanced Triple Negative Breast CancerRecruitingNCT06637306Early Phase 1
• Immunologic Impact of Dupilumab in Patients Suffering From Asthma and Chronic Rhinosinusitis With PolypsNot yet recruitingNCT06556264Phase 4
• Dupilumab as Add-On Therapy for Hypereosinophilic Syndrome With Partial Clinical Response to Eosinophil-Depleting Biologic AgentsRecruitingNCT06477653Phase 2
• Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and EndotypingRecruitingNCT06385236Phase 4
• A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥6 Months to <18 Years of Age With Prurigo NodularisRecruitingNCT06293053Phase 3
• Dupixent in Adults With Refractory Post-Burn Pruritus in an Ambulatory ClinicRecruitingNCT06226610Phase 2
• Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)Enrolling by invitationNCT06191315Phase 3
• Neoadjuvant Dupilumab and Cemiplimab in Patients With Early-stage Resectable NSCLCRecruitingNCT06088771Phase 1/2
• DUPIlumab Dose REDUCtion in Patients With Controlled Atopic EczemaRecruitingNCT06004986Phase 4
• PD-1 +/- IL-4 Inhibition in ER+ Breast CancerNot yet recruitingNCT05967884Phase 2
• Dupilumab in the Treatment of Pediatric Alopecia AreataRecruitingNCT05866562Phase 2
• Molecular Signatures of Cutaneous Dupilumab ResponseRecruitingNCT05858619Phase 4
• Repurposing Dupilumab for Management of Pruritic Genetic Inflammatory Skin DisordersRecruitingNCT05649098Early Phase 1
• Regeneron AA Multicenter (Dupilumab)RecruitingNCT05551793Phase 2
• Dupixent and Narrowband UVB for Atopic DermatitisRecruitingNCT05285839Phase 4
• Ethnic Differences in Mechanisms of Action of DupilumabRecruitingNCT05268107Phase 4
• Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)RecruitingNCT05263206Phase 3
• Interleukin-4Ra Blockade by Dupilumab Decreases Staphylococcus Colonization and Increases Microbial Diversity in CRSwNPRecruitingNCT05094570Phase 4
• Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic DermatitisRecruitingNCT05042258Phase 4
• Measuring the Effect of Dupilumab Treatment on Mucociliary Clearance (MCC) in Subjects With Moderate to Severe AsthmaRecruitingNCT04743791Phase 4
• Viral Infection in Asthma (VIA) StudyRecruitingNCT04380038Phase 4
• Evaluation of Dupilumab in Patients With Atopic Keratoconjunctivitis (AKC)RecruitingNCT04296864Phase 2
• Mechanisms of Smell Improvement With Dupilumab.CompletedNCT05964465Phase 4Results posted
• Dupilumab in Chinese Adult Participants With CRSwNPCompletedNCT05878093Phase 3Results posted
• A Study to Evaluate Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Adolescent and Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT05601882Phase 3Results posted
• Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema TrialCompletedNCT05590585Phase 4Results posted
• Add-on Dupilumab for AFRS as Postoperative Therapy (ADAPT)TerminatedNCT05545072Phase 3Results posted
• A Study to Investigate the Pharmacokinetics and Safety of Dupilumab in Participants ≥2 Years to <12 Years of Age With Uncontrolled Chronic Spontaneous Urticaria (CSU) (LIBERTY-CSU CUPIDKids)CompletedNCT05526521Phase 3Results posted
• Longitudinal Endotyping Of Atopic Dermatitis Through Transcriptomic Skin AnalysisCompletedNCT05436535Phase 4Results posted
• Efficacy of Dupilumab on Facilitated Food Introduction in Eosinophilic EsophagitisCompletedNCT05247866Phase 4Results posted
• Study to Assess Efficacy and Safety of Dupilumab in the Treatment of KeloidsCompletedNCT05128383Phase 2Results posted
• Dupilumab in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyp (SINUS-M52)CompletedNCT05049122Phase 4Results posted
• Effects of Interleukin (IL)- 4R-alpha Inhibition on Respiratory Microbiome and Immunologic Correlates in Severe AsthmaCompletedNCT05036733Phase 4Results posted
• EValuating trEatment RESponses of Dupilumab Versus Omalizumab in Type 2 PatientsCompletedNCT04998604Phase 4Results posted
• Safety and Efficacy of Dupilumab for Treatment of Hospitalized COVID-19 PatientsCompletedNCT04920916Phase 2Results posted
• Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic DermatitisCompletedNCT04823130Phase 4Results posted
• Dupilumab-PEdiatric Skin Barrier Function and LIpidomics STudy in Patients With Atopic DermatitisCompletedNCT04718870Phase 4Results posted
• Dupilumab in Allergic Fungal Rhinosinusitis (AFRS)CompletedNCT04684524Phase 3Results posted
• Dupilumab in CRSsNPCompletedNCT04678856Phase 2Results posted
• Grass Pollen Immunotherapy Plus Dupilumab for Tolerance InductionCompletedNCT04502966Phase 2Results posted
• A Phase 4, Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study of the Effect of Dupilumab on Sleep Disturbance in Patients With Uncontrolled Persistent AsthmaCompletedNCT04502862Phase 4Results posted
• Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate to Severe COPD With Type 2 InflammationCompletedNCT04456673Phase 3Results posted
• Dupilumab Skin Barrier Function Study in Atopic DermatitisCompletedNCT04447417Phase 4Results posted
• Investigating Treatment With Dupilumab in Patients With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)CompletedNCT04442269Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Moderate-to-Severe Atopic Hand and Foot Dermatitis (Liberty-AD-HAFT)CompletedNCT04417894Phase 3Results posted
• The Effect of Dupilumab on Lung Inflammation and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe AsthmaCompletedNCT04400318Phase 4Results posted
• Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE)CompletedNCT04394351Phase 3Results posted
• Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic PruritusCompletedNCT04256759Phase 2Results posted
• A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous PemphigoidCompletedNCT04206553Phase 2/3Results posted
• A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With AsthmaCompletedNCT04203797Phase 4Results posted
• Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (PRIME2)CompletedNCT04202679Phase 3Results posted
• Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (LIBERTY-PN PRIME)CompletedNCT04183335Phase 3Results posted
• Dupilumab and Milk OIT for the Treatment of Cow's Milk AllergyTerminatedNCT04148352Phase 2Results posted
• SAR231893-LPS15497- "Dupilumab Effect on Sleep in AD Patients"CompletedNCT04033367Phase 4Results posted
• The Effects of Dupilumab on Allergic Contact DermatitisActive, not recruitingNCT03935971Phase 4Results posted
• Pivotal Study to Assess the Efficacy, Safety and Tolerability of Dupilumab in Patients With Moderate-to-severe COPD With Type 2 InflammationCompletedNCT03930732Phase 3Results posted
• Evaluation of Dupilumab in Chinese Adult Patients With Moderate to Severe Atopic DermatitisCompletedNCT03912259Phase 3Results posted
• Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate CancerTerminatedNCT03886493Phase 2Results posted
• Study to Evaluate Dupilumab Monotherapy in Pediatric Patients With Peanut AllergyCompletedNCT03793608Phase 2Results posted
• A Study to Compare Safety and Efficacy of Upadacitinib to Dupilumab in Adult Participants With Moderate to Severe Atopic DermatitisCompletedNCT03738397Phase 3Results posted
• Efficacy and Safety of REGN3500 Monotherapy and Combination of REGN3500 Plus Dupilumab in Adult Patients With Moderate-to-Severe Atopic DermatitisTerminatedNCT03736967Phase 2Results posted
• Study in Pediatric Subjects With Peanut Allergy to Evaluate Efficacy and Safety of Dupilumab as Adjunct to AR101 (Peanut Oral Immunotherapy)CompletedNCT03682770Phase 2Results posted
• Clinical Study Using Biologics to Improve Multi OIT Outcomes (COMBINE)CompletedNCT03679676Phase 2Results posted
• Dupilumab in Eosinophilic GastritisCompletedNCT03678545Phase 2Results posted
• The Impact of Dupilumab on Quality of Life in Moderate to Severe Atopic Dermatitis PatientsCompletedNCT03667014Phase 4Results posted
• Study to Determine the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Eosinophilic Esophagitis (EoE)CompletedNCT03633617Phase 3Results posted
• Continuation of TRAVERSE- LTS12551 Evaluating Dupilumab Safety in Patients With Asthma (Long-Term Follow-Up)CompletedNCT03620747Phase 3Results posted
• Assessment of the Safety and Efficacy of Dupilumab in Children With Asthma (Liberty Asthma Excursion)CompletedNCT03560466Phase 3Results posted
• Dupilumab As An Adjunct For Subcutaneous Grass ImmunotherapyCompletedNCT03558997Phase 2Results posted
• Effect of Dupilumab (Anti-IL4Rα) on the Host-Microbe Interface in Atopic DermatitisTerminatedNCT03389893Phase 4Results posted
• Evaluation of SAR440340 and as Combination Therapy With Dupilumab in Moderate-to-Severe Asthma ParticipantsCompletedNCT03387852Phase 2Results posted
• Treatment of Alopecia Areata (AA) With Dupilumab in Patients With and Without Atopic Dermatitis (AD)CompletedNCT03359356Phase 2Results posted
• Safety, Pharmacokinetics and Efficacy of Dupilumab in Patients ≥6 Months to <6 Years With Moderate-to-Severe Atopic Dermatitis (Liberty AD PRESCHOOL)CompletedNCT03346434Phase 2/3Results posted
• Study to Investigate the Efficacy and Safety of Dupilumab Administered With Topical Corticosteroids (TCS) in Participants ≥6 to <12 Years With Severe Atopic Dermatitis (AD)CompletedNCT03345914Phase 3Results posted
• Immunogenetic Profiling of Dupilumab for the Treatment of Atopic DermatitisCompletedNCT03293030Phase 4Results posted
• Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic DermatitisCompletedNCT03054428Phase 3Results posted
• Evaluation of Dupilumab in Children With Uncontrolled AsthmaCompletedNCT02948959Phase 3Results posted
• A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal PolypsCompletedNCT02912468Phase 3Results posted
• Controlled Clinical Study of Dupilumab in Patients With Nasal PolypsCompletedNCT02898454Phase 3Results posted
• A Study to Assess the Efficacy and Safety of Dupilumab in Participants With Severe Atopic Dermatitis (AD) That Are Not Controlled With Oral Cyclosporine A (CSA) or for Those Who Cannot Take Oral CSA Because it is Not Medically AdvisableCompletedNCT02755649Phase 3Results posted
• Evaluation of Dupilumab in Patients With Severe Steroid Dependent AsthmaCompletedNCT02528214Phase 3Results posted
• Evaluation of Dupilumab in Patients With Persistent Asthma (Liberty Asthma Quest)CompletedNCT02414854Phase 3Results posted
• A Study to Determine the Safety and Tolerability of Dupilumab (REGN668/SAR231893) in Patients Aged ≥6 to <18 Years With Atopic Dermatitis (Eczema)CompletedNCT02407756Phase 2Results posted
• A Study to Confirm the Efficacy and Safety of Different Dupilumab Dose Regimens in Adults With Atopic Dermatitis (AD)CompletedNCT02395133Phase 3Results posted
• Study of Dupilumab in Adult Participants With Active Eosinophilic Esophagitis (EoE)CompletedNCT02379052Phase 2Results posted
• Study of Dupilumab (REGN668/SAR231893) Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic DermatitisCompletedNCT02277769Phase 3Results posted
• Study of Dupilumab Monotherapy Administered to Adult Patients With Moderate-to-Severe Atopic DermatitisCompletedNCT02277743Phase 3Results posted
• Study to Assess the Efficacy and Long-term Safety of Dupilumab (REGN668/SAR231893) in Adult Participants With Moderate-to-Severe Atopic DermatitisCompletedNCT02260986Phase 3Results posted
• Study of Dupilumab and Immune Responses in Adults With Atopic Dermatitis (AD)CompletedNCT02210780Phase 2Results posted

← Dupilumab overview