Dornase alfa: all 32 studies that test it
Page 1 of 1. Open to participants first (4), then studies with results posted, then the rest; newest registration first within each.
- Dornase Alfa and Cisplatin in Refractory Germ Cell Cancer.RecruitingNCT07121322Phase 2
- Reduction of SystemiC Inflammation After Ischemic Stroke by Intravenous DNase Administration (ReSCInD)RecruitingNCT05880524Phase 2
- Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory FailureRecruitingNCT04445285Phase 2
- Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe TraumaRecruitingNCT03368092Phase 3
- rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host DiseaseTerminatedNCT02702518Phase 1/2Results posted
- Efficacy of Percussive Ventilation Therapy (MetaNeb ®) Compared With Mucolytic Agents for Atelectasis in the Mechanically Ventilated Pediatric PatientCompletedNCT02168387Phase 4Results posted
- Preliminary Study of Dornase Alfa to Treat Chest Infections Post Lung Transplant.CompletedNCT01952470Phase 2Results posted
- A Study of the Comparable Efficacy and Safety of Pulmozyme (Dornase Alfa) Delivered by the eRapid Nebulizer System in Patients With Cystic FibrosisCompletedNCT01712334Phase 4Results posted
- Dornase Alfa Therapy for Ventilator Associated Lung Infections in the Neonatal Intensive Care Unit (NICU)CompletedNCT01356147Phase 4Results posted
- A Study of Pulmozyme® (Dornase Alpha) in 3- to 5-Year-Old Patients With Cystic FibrosisTerminatedNCT00680316Phase 4Results posted
- Dornase Alpha Versus Hypertonic Saline for Lung Atelectasis in Non-Cystic Fibrosis PatientsCompletedNCT00671723Not applicableResults posted
- A Trial of Pulmozyme Withdrawal on Exercise Tolerance in Cystic Fibrosis Subjects With Severe Lung Disease (TOPIC)TerminatedNCT00434278Phase 4Results posted
- Treatment of Clogged Tympanostomy Tubes: An Off-Label Use of Dornase Alfa (Pulmozyme®)CompletedNCT00419380Phase 4Results posted
- Nasally Delivered Pulmozyme for Sinusitis in Cystic FibrosisCompletedNCT00416182Phase 2Results posted
- Effectiveness of Pulmozyme in Infants With Cystic FibrosisCompletedNCT00179998Phase 2Results posted
- Combination of Inhaled DNase, Baricitinib and Tocilizumab in Severe COVID-19Status unknownNCT05279391Not applicable
- Improving Early Reperfusion With Adjuvant Dornase Alfa in Large Vessel Ischemic Stroke (EXTEND-IA DNase)CompletedNCT05203224Phase 2
- Usefulness of DORNASE in COVID-19 on HFNOTerminatedNCT05139901Phase 4
- I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill PatientsActive, not recruitingNCT04488081Phase 2
- Dornase Alpha for the Treatment of COVID-19Status unknownNCT04432987Phase 2
- DISmantling COvid iNduced Neutrophil ExtraCellular Traps (DISCONNECT-1)CompletedNCT04409925Phase 1
- Pulmozyme to Improve COVID-19 ARDS OutcomesStatus unknownNCT04402944Phase 2
- The Safety and Tolerability of Intra-abdominal t-PA and DNase on Peritonitis in Peritoneal Dialysis PatientsTerminatedNCT01478698Phase 1
- Impact of Nebulized Dornase Alpha on Mechanically Ventilated PatientsCompletedNCT01095276Not applicable
- RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis SputumCompletedNCT00843817Phase 4
- The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic FibrosisCompletedNCT00557089Phase 4
- Pilot Study of Pulmozyme (rhDNase) in Patients With Head and Neck Cancers Treated With Radiation Therapy + ChemotherapyStatus unknownNCT00536952Early Phase 1
- Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic RhinosinusitisCompletedNCT00534079Phase 3
- Dornase Alfa and Urokinase for Kids With Pleural EmpyemaStatus unknownNCT00502632Phase 2/3
- Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic RhinosinusitisCompletedNCT00265434Phase 3
- Time of Ventilation and Lung Function of Ventilated Patients Under Therapy With Dornase AlfaStatus unknownNCT00204685Phase 2/3
- Study of Pulmozyme to Treat Severe Asthma EpisodesCompletedNCT00169962Phase 2