Dipeptidyl-Peptidase IV Inhibitors: all 899 studies that test it

Page 2 of 9. Open to participants first (28), then studies with results posted, then the rest; newest registration first within each.

• Effect of Chronic ACE and DPP4 Inhibition on Blood PressureCompletedNCT02130687Not applicableResults posted
• The Effect of Dipeptidyl Peptidase 4 Inhibition on Growth Hormone Secretion in Women With Polycystic Ovarian SyndromeCompletedNCT02122380Phase 4Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/750mg) Extended Release in Healthy SubjectsCompletedNCT02121509Phase 1Results posted
• Evaluate the Efficacy and Safety of Saxagliptin Added to Insulin Monotherapy or to Insulin Combined With Metformin in Chinese Subjects With Type 2 Diabetes Who Have Inadequate Glycaemic ControlCompletedNCT02104804Phase 3Results posted
• Ertugliflozin and Sitagliptin Co-administration Factorial Study (VERTIS FACTORAL, MK-8835-005)CompletedNCT02099110Phase 3Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (5mg/1000mg) Extended Release in Healthy SubjectsCompletedNCT02084082Phase 1Results posted
• Bioequivalence of a FDC Tablet of Linagliptin/Metformin (2.5mg/1000mg) Extended Release in Healthy Subjects.CompletedNCT02084056Phase 1Results posted
• Efficacy and Safety Study of Teneligliptin (MP-513) in Combination With Insulin in Patients With Type 2 DiabetesCompletedNCT02081599Phase 4Results posted
• ADA Linagliptin in Long Term CareCompletedNCT02061969Phase 4Results posted
• Use of Sitagliptin to Decrease MicroalbuminuriaTerminatedNCT02048904Phase 4Results posted
• Effect of Saxagliptin on EPCs as a Cellular Biomarker for Evaluating Endothelial Dysfunction in Early T2DM PatientsCompletedNCT02024477Phase 4Results posted
• Januvia (Sitagliptin) in Healing Chronic Diabetic Foot UlcersTerminatedNCT02015910Phase 4Results posted
• Glycemic Excursions in Type 2 Diabetic Patients With Vildagliptin and Metformin Versus Vildagliptin and GlimepirideCompletedNCT02007278Phase 4Results posted
• Linagliptin Inpatient TrialCompletedNCT02004366Phase 4Results posted
• Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM PatientsCompletedNCT02002221Phase 4Results posted
• Use of Sitagliptin for Stress Hyperglycemia or Mild Diabetes Following Cardiac SurgeryTerminatedNCT01970462Phase 4Results posted
• The Effect of Linagliptin on Mitochondrial and Endothelial FunctionCompletedNCT01969084Phase 4Results posted
• Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver DiseaseCompletedNCT01963845Phase 2Results posted
• Impact of Sitagliptin on Cardiovascular Exercise Performance in Type 2 DiabetesCompletedNCT01951339Not applicableResults posted
• Two-way Crossover Study in Healthy Male and Female Subjects to Evaluate the Bioequivalence of Jentadueto®.CompletedNCT01947153Phase 1Results posted
• Antidiabetic Effects of Adding a DPP-4 Inhibitor to Pre-Existing Treatment With an Incretin Mimetic in Patients With T2DCompletedNCT01937598Phase 3Results posted
• Efficacy Study of Sitagliptin to Prevent New-onset Diabetes After Kidney TransplantCompletedNCT01928199Phase 4Results posted
• Comparison of Vildagliptin vs. Glimepiride on Glucose Variability in Metformin Uncontrolled Type 2 Diabetic PatientsTerminatedNCT01910441Phase 4Results posted
• Efficacy and Safety of Switching From Sitagliptin to Liraglutide in Subjects With Type 2 Diabetes Not Achieving Adequate Glycaemic Control on Sitagliptin and MetforminCompletedNCT01907854Phase 4Results posted
• Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA)CompletedNCT01897532Phase 4Results posted
• Efficacy and Safety of Alogliptin and Metformin Fixed-Dose Combination in Participants With Type 2 DiabetesCompletedNCT01890122Phase 3Results posted
• Safety and Efficacy Study to Compare Vildagliptin to Pioglitazone as Adding on Metformin in Type 2 DiabetesCompletedNCT01882907Phase 4Results posted
• Effect of Chronic Incretin-based Therapy in Cystic FibrosisCompletedNCT01879228Not applicableResults posted
• Vildagliptin/Metformin in T2DM Patients Starting Basal InsulinCompletedNCT01871558Phase 3Results posted
• A Study to Evaluate the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus for Whom Metformin is Inappropriate (MK-3102-027)TerminatedNCT01863667Phase 3Results posted
• Effects of Sitagliptin on Endothelial Function in Type 2 Diabetes on Background Metformin TherapyCompletedNCT01859793Phase 4Results posted
• Sitagliptin Therapy in Hospitalized Patients With Type 2 DiabetesCompletedNCT01845831Phase 4Results posted
• Relative Bioavailability of 2 Fixed Dose Combinations of Linagliptin/Metformin Compared With Single TabletsCompletedNCT01845077Phase 1Results posted
• Study to Evaluate the Safety and Efficacy of the Addition of Omarigliptin (MK-3102) Compared With the Addition of Sitagliptin in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-026)CompletedNCT01841697Phase 3Results posted
• Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 DiabetesCompletedNCT01822548Phase 3Results posted
• A Study of the Safety and Efficacy of Omarigliptin (MK-3102) in ≥18 and <45 Year-Old Participants With Type 2 Diabetes Mellitus and Inadequate Glycemic Control (MK-3102-028)CompletedNCT01814748Phase 3Results posted
• A Comparative Effectiveness Study of Major Glycemia-lowering Medications for Treatment of Type 2 DiabetesCompletedNCT01794143Phase 3Results posted
• MARLINA - T2D : Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptinCompletedNCT01792518Phase 3Results posted
• Linagliptin as Add on Therapy to Empagliflozin 10 mg or 25 mg With Background Metformin in Patient With Type 2 DiabetesCompletedNCT01778049Phase 3Results posted
• A Pharmacokinetic Study of MK-3102 in Participants With Impaired Hepatic Function (MK-3102-031)CompletedNCT01767688Phase 1Results posted
• Early add-on Vildagliptin in Patients With Type 2 Diabetes Inadequately Controlled by MetforminCompletedNCT01766778Phase 4Results posted
• Mechanistic Assessment of the Properties of Saxagliptin in Subjects Undergoing Coronary Artery Bypass Graft SurgeryTerminatedNCT01765270Phase 4Results posted
• A Pooled Analysis of the Safety and Efficacy of MK-0431A and MK-0431A XR in Pediatric Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Therapy (Alone or in Combination With Insulin) (MK-0431A-170/MK-0431A-289)CompletedNCT01760447Phase 3Results posted
• A Study to Evaluate the Safety, Tolerability, and Efficacy of the Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Metformin Therapy (MK-3102-024)CompletedNCT01755156Phase 3Results posted
• Safety and Efficacy of the Combination of Empagliflozin and Linagliptin Compared to Linagliptin Alone Over 24 Weeks in Patients With Type 2 DiabetesCompletedNCT01734785Phase 3Results posted
• Multicenter Phase II of CD26 Using Sitagliptin for Engraftment After UBC TransplantCompletedNCT01720264Phase 2Results posted
• A Study to Assess the Safety and Efficacy of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (T2DM) and Inadequate Glycemic Control (MK-3102-011)CompletedNCT01717313Phase 3Results posted
• Study to Compare the Efficacy and Safety of Administration of the Fix Dose Combination of Linagliptin Plus Metformin in Drug naïve Type 2 PatientsCompletedNCT01708902Phase 3Results posted
• Addition of Omarigliptin (MK-3102) to Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control on Combination Therapy With Glimepiride and Metformin (MK-3102-022)CompletedNCT01704261Phase 3Results posted
• Trial to Assess the Influence of 4 Weeks' Treatment With Linagliptin as Compared to Glimepiride and Placebo on Endothelial Function in Patients With Type 2 Diabetes Using FMD (Flow-Mediated Vasodilation)CompletedNCT01703286Phase 1Results posted
• A Study to Assess Cardiovascular Outcomes Following Treatment With Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus (MK-3102-018)TerminatedNCT01703208Phase 3Results posted
• A Study to Assess the Safety and Tolerability of Sitagliptin/Simvastatin Fixed-dose Combination (FDC) in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-312)CompletedNCT01702298Phase 3Results posted
• A Study of Omarigliptin (MK-3102) in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019)CompletedNCT01698775Phase 3Results posted
• Omarigliptin (MK-3102) Clinical Trial - Add-on to Oral Antihyperglycemic Agent Study in Japanese Participants With Type 2 Diabetes Mellitus (MK-3102-015)CompletedNCT01697592Phase 3Results posted
• Vildagliptin vs Sitagliptin add-on to Insulin - Impact on Glycemic Profile and Correlation of Hypoglycemic Episodes and Heart FunctionCompletedNCT01686932Phase 4Results posted
• A Study of the Safety and Efficacy of Omarigliptin (MK-3102) Compared With Glimepiride in Participants With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Metformin (MK-3102-016)CompletedNCT01682759Phase 3Results posted
• A Study of the Efficacy and Safety of MK-0431D (a Fixed-dose Combination of Sitagliptin and Simvastatin) for the Treatment of Participants With Type 2 Diabetes Mellitus (T2DM) With Inadequate Glycemic Control on Metformin Monotherapy (MK-0431D-266)TerminatedNCT01678820Phase 3Results posted
• Roflumilast Plus Alogliptin Proof-of-Mechanism Study in Type2 DiabetesCompletedNCT01664624Phase 1Results posted
• Drug Interaction Study of Saxagliptin in Combination With Dapagliflozin in Healthy ParticipantsCompletedNCT01662999Phase 1Results posted
• A Single-dose Phase 1 Study of DBPR108 in Healthy Male SubjectsCompletedNCT01650324Phase 1Results posted
• Safety and Efficacy of Saxagliptin in Triple Therapy to Treat Subjects With Type 2 DiabetesCompletedNCT01619059Phase 3Results posted
• Contribution of Pancreatic αcells Function to Blood Glucose Regulation in Chinese Type 2 Diabetics- the Effect of Sitagliptin on Glucagon Secretion, Insulin Secretion and Insulin Resistance in Chinese Type 2 DiabeticsCompletedNCT01610154Phase 4Results posted
• The Efficacy and Safety Study in Patients With Type 2 Diabetes MellitusCompletedNCT01608724Phase 4Results posted
• Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 DiabetesCompletedNCT01606007Phase 3Results posted
• Sitagliptin Regulation of Intestinal and Hepatic Lipoprotein Particle and Hepatic Glucose Production in HumansCompletedNCT01600703Phase 2/3Results posted
• A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Insulin With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-254)CompletedNCT01590797Phase 3Results posted
• A Study in China Evaluating the Safety and Efficacy of Adding Sitagliptin to Stable Therapy With Sulfonylurea With or Without Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-253)CompletedNCT01590771Phase 3Results posted
• A Study Comparing the Pharmacokinetic and Pharmacodynamic Profiles for Sitagliptin, Saxagliptin and Vildagliptin in Participants With Type 2 Diabetes Mellitus (T2DM) (MK-0431-142)CompletedNCT01582308Phase 1Results posted
• Safety and Efficacy of Vildagliptin Plus Metformin (SPC) Treatment in Type 2 Diabetes Mellitus PatientsCompletedNCT01582243Phase 4Results posted
• Bioequivalence of Metformin Under Fed Conditions After Administration of Linagliptin / Metformin Fixed Dose Combination Tablet and Single TabletsCompletedNCT01581931Phase 1Results posted
• A Study to Assess the Pharmacokinetics and the Ability for Pediatric Participants With Type 2 Diabetes to Swallow MK-0431A XR Tablets (MK-0431A-296)CompletedNCT01557504Phase 1Results posted
• Effectiveness of Sitagliptin for HIV Insulin Resistance and InflammationCompletedNCT01552694Phase 3Results posted
• Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte InflammationTerminatedNCT01548651Phase 4Results posted
• Pharmacokinetics of Fixed Dose Combination (FDC) Tablets of Linagliptin /MetforminCompletedNCT01540487Phase 1Results posted
• Evaluation of Continuous Glucose Monitoring in Participants With Type 2 Diabetes Mellitus (MK-0000-258 AM2)CompletedNCT01537120Phase 1Results posted
• Sitagliptin Dose Determination StudyCompletedNCT01530178Phase 4Results posted
• Study of Saxagliptin, 5-Hydroxy Saxagliptin, and Metformin Concentrations/Levels in Pediatric Subjects With T2DMTerminatedNCT01525225Phase 1Results posted
• Treatment Intensification With Biphasic Insulin Aspart 30 in Subjects With Type 2 Diabetes Inadequately Controlled on Sitagliptin and MetforminCompletedNCT01519674Phase 4Results posted
• Treatment of Diabetes After Gastric Bypass With SitagliptinCompletedNCT01512797Not applicableResults posted
• Study to Assess Safety & Efficacy of Sitagliptin as Initial Oral Therapy for Treatment of Type 2 Diabetes Mellitus in Pediatric Participants. (MK-0431-083)CompletedNCT01485614Phase 3Results posted
• A Study of the Co-administration of Sitagliptin and Atorvastatin in Inadequately Controlled Type 2 Diabetes Mellitus (MK-0431E-211)TerminatedNCT01477853Phase 3Results posted
• DPP IV Inhibition Facilitates Healing of Chronic Foot Ulcers in Type 2 DiabetesCompletedNCT01472432Phase 4Results posted
• Study of Sitagliptin for the Treatment of Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Insulin (MK-0431-260)CompletedNCT01462266Phase 3Results posted
• Long-term Study of Alogliptin as an Add-on to Rapid-Acting Insulin Secretagogues in Type 2 DiabetesCompletedNCT01456130Phase 3Results posted
• Pharmacokinetics Study of Dipeptidyl Peptidase 4 Inhibitor to Control Type 2 Diabetes MellitusCompletedNCT01449747Phase 4Results posted
• Linagliptin in Combination With Metformin in Treatment Naive Patients With Type 2 Diabetes Mellitus and Insufficient Glycaemic ControlCompletedNCT01438814Phase 4Results posted
• A Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Saxagliptin (BMS-477118) in Combination With Metformin IR or Metformin XR in Pediatric Patients With Type 2 Diabetes Who Have Inadequate Glycemic Control on Metformin AloneCompletedNCT01434186Phase 3Results posted
• A Study of LY2189265 and Sitagliptin in Participants With Type 2 DiabetesCompletedNCT01408888Phase 1Results posted
• A Study of Omarigliptin (MK-3102) in Participants With Impaired Renal Function (MK-3102-009)CompletedNCT01407276Phase 1Results posted
• Dose Response Finding Study of MK-0431/ONO-5435 in Japanese Subjects With Impaired Glucose Tolerance (MK-0431-105)CompletedNCT01405911Phase 2Results posted
• Pharmacokinetics and Pharmacodynamics Study of Alogliptin in Healthy Korean ParticipantsCompletedNCT01391663Phase 1Results posted
• Dipeptidyl Peptidase-4 Inhibitor (Sitagliptin) Therapy in the Inpatients With Type 2 DiabetesCompletedNCT01378117Phase 4Results posted
• Changes in Bone Turnover With Increased Incretin Hormone ExposureTerminatedNCT01374568Phase 4Results posted
• Bioequivalence Study of Fixed-dose Combinations and Coadministered Individual Tablets of Saxagliptin/Metformin-BrazilCompletedNCT01365091Phase 1Results posted
• Finding a Safe and Effective Dose of Linagliptin in Pediatric Patients With Type 2 DiabetesCompletedNCT01342484Phase 2Results posted
• Study to Compare Sitagliptin Versus Sulfonylurea Treatment During Ramadan Fasting in Patients With Type 2 Diabetes (MK-0431-262)CompletedNCT01340768Phase 3Results posted
• Sitagliptin and Kinetics of Triglyceride-rich Lipoproteins Apolipoprotein B48 and B100 in Patients With Type 2 DiabetesCompletedNCT01334229Phase 3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Sulfonylurea or Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318135Phase 2/3Results posted
• Long-term Safety Study of Alogliptin Used in Combination With Thiazolidine in Participants With Type 2 Diabetes in JapanCompletedNCT01318122Phase 2/3Results posted
• Efficacy and Safety of Alogliptin Used Combination With Metformin in Participants With Type 2 Diabetes in JapanCompletedNCT01318109Phase 2/3Results posted

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