Denatonium clinical trials
Includes 5 studies of Denatonium acetate monohydrate.
How each study uses denatonium is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Name
- Denatonium Benzoate
- 2
Studies by the year they started
7 studies that test it; most in 2022 (2)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2019 | 1 |
| 2021 | 1 |
| 2022 | 2 |
| 2024 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 5 · Other 2
Aardvark Therapeutics, Inc. (5) · Universitaire Ziekenhuizen KU Leuven (2)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses denatonium is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 7
- A Study of Oral ARD-101 in Patients With Prader-Willi SyndromeCompletedPhase 2Aardvark Therapeutics, Inc.NCT05153434Written as ARD-101
- ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective TrialTerminatedPhase 3Aardvark Therapeutics, Inc.NCT06828861Written as ARD-101
- The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) TrialTerminatedPhase 3Aardvark Therapeutics, Inc.NCT07197034Written as ARD-101
- Study to Evaluate ARD-101 in Adults Receiving Bariatric SurgeryCompletedPhase 2Aardvark Therapeutics, Inc.NCT05215847Written as ARD-101
- Study to Evaluate ARD-101 in Adults With ObesityCompletedPhase 2Aardvark Therapeutics, Inc.NCT05121441Written as ARD-101
- Bitter Tastants and RefluxCompletedNot applicableUniversitaire Ziekenhuizen KU LeuvenNCT03777787Written as Denatonium Benzoate
- The Effect of Bitter Taste Receptor Agonists on The Gastrointestinal Tract, Hunger and Food IntakeStatus unknownNot applicableUniversitaire Ziekenhuizen KU LeuvenNCT02759926Written as Denatonium benzoate
Codes
What other systems call denatonium · ClinicalTrials.gg INT003173
- MeSH (NLM) C043414denatoniumConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) 4IK22DF4OUDENATONIUMConfirmed FDA, NLM, Wikidata
- RxNorm 1546417Confirmed FDA, Wikidata
- Wikidata Q27167097denatoniumConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C83659DenatoniumOne source FDA
- DrugBank DB18588One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C043414 | denatonium | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | 4IK22DF4OU | DENATONIUM | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1546417 | — | Confirmed FDA, Wikidata |
| Wikidata | Q27167097 | denatonium | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C83659 | Denatonium | One source FDA |
| DrugBank | DB18588 | — | One source Wikidata |
Also registered as denatonium benzoate (UNII 4YK5Z54AT2 · RxNorm 1313232) and denatonium chloride (UNII 0W5171805N).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.