Cyclooxygenase 2 Inhibitors: all 667 studies that test it

Page 3 of 7. Open to participants first (39), then studies with results posted, then the rest; newest registration first within each.

• The Seven Trial: Exploiting the Unfolded Protein ResponseTerminatedNCT06076837Phase 1
• CA102N Combined With TAS-102 Compared to Bevacizumab Combined With TAS-102 in Subjects With Metastatic Colorectal CancerSuspendedNCT06039202Phase 2
• Pain Treatment With Combinations of NSAIDsCompletedNCT05994287Not applicable
• Multimodal Pain Package vs. Regular Formulation for Pain Management in Ambulatory Spinal SurgeryWithdrawnNCT05965492Phase 3
• Role of Pentoxifylline and Celecoxib in ParkinsonismCompletedNCT05962957Phase 2
• Effect of Preemptive Etoricoxib and Dexamethasone on Wound Healing and Clinical Parameters After Third Molar SurgeryCompletedNCT05791721Phase 4
• Efficacy of Parecoxib Combined With Paracetamol in MastectomyStatus unknownNCT05757388Not applicable
• Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial CraniotomyCompletedNCT05681429Not applicable
• Multimodal and Unimodal Analgesia in CholecystectomyCompletedNCT05547659Phase 1/2
• Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in CombinationCompletedNCT05533073Phase 1
• Bioequivalence Study of Etoricoxib in Healthy Adult Subjects Under Fasting ConditionCompletedNCT05532280Phase 1
• The Effects of NSAIDs on Bone Metabolism Following ExerciseCompletedNCT05512013Phase 1
• Study to Assess the Effect of Co-Administration of AZD9833 on the Pharmacokinetics of Midazolam, of Omeprazole, of Celecoxib and of Dabigatran Etexilate in Healthy Postmenopausal Female VolunteersCompletedNCT05438303Phase 1
• A Multiple-Dose PK Study to Evaluate the Comparative Bioavailability of PrimeC Tablets to Ciprofloxacin Tablets Co-administered With Celecoxib Capsules, in Healthy Adult SubjectCompletedNCT05436678Phase 1
• Treating Immuno-metabolic Depression With Anti-inflammatory DrugsCompletedNCT05415397Phase 3
• Drug-Drug Interaction Study of "CG-651" in Healthy VolunteerCompletedNCT05370716Phase 1
• Possible Protective Effect of Celecoxib Against Capecitabine Induced Hand and Foot Syndrome in Patients With Colorectal CancerStatus unknownNCT05327751Phase 3
• Peri-Articular-Multimodal Drug and Oral Celecoxib in Management of Postoperative Pain of Total Knee ArthroplastyCompletedNCT05324995Phase 2
• Celecoxib in Postoperative Analgesia for Radius Fracture SurgeryCompletedNCT05288374Phase 4
• Chidamide + Celecoxib in Advanced Metastatic Colorectal Cancer (CCmCC)TerminatedNCT05281276Phase 1
• Evaluation of the Effects of Treatments Applied to Patients With Facial Myalgia on Occlusion ParametersCompletedNCT05261971Not applicable
• Safety and Efficacy of Celecoxib Plus Nucleos(t)Ide Analogues on the Hepatitis B Surface Antigen of Virally Suppressed Subjects With Chronic Hepatitis BStatus unknownNCT05256823Phase 2
• Biomarkers for Prediction of Analgesic Efficacy in Knee OA.CompletedNCT05256342Not applicable
• Study to Evaluate Pharmacokinetic Drug Interactions and Safety of Naproxen, Aceclofenac, Celecoxib and IlaprazoleCompletedNCT05237297Phase 1
• A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult SubjectsCompletedNCT05232461Phase 1
• Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery.CompletedNCT05150431Phase 4
• Comparison of the Anti-Inflammatory Efficacy of Preemptive Dexamethasone and EtoricoxibStatus unknownNCT05142098Early Phase 1
• Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting ConditionCompletedNCT05125588Phase 1
• A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.Active, not recruitingNCT05109312Phase 4
• Effectiveness of Premedication on the Success Rate of Inferior Alveolar Nerve BlockCompletedNCT05097768Not applicable
• Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)WithdrawnNCT05085574Phase 2
• LEAP-CT for Treatment of COVID-19 Patients (Master Protocol)CompletedNCT05077332Phase 2
• Efficacy and Safety of Fixed-dose Combination of Etoricoxib/Tramadol vs Acetaminophen/Tramadol for Acute Low Back PainCompletedNCT04968158Phase 3
• ECP-1014 Treatment for Patients With Solid Tumor CancersStatus unknownNCT04930354Phase 1
• HTX-011 in Spinal SurgeryCompletedNCT04911062Phase 2
• Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section.CompletedNCT04847024Not applicable
• Bioequivalence Study of Two Formulations of Etoricoxib Tablets 120 mg in Healthy Volunteers Under Fasting ConditionsStatus unknownNCT04830579Phase 1
• The Effect of Celecoxib on Neuroinflammation in MDDCompletedNCT04814355Phase 4
• Neuroinflammation in Patients With OCDSuspendedNCT04786548Phase 2
• Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?Status unknownNCT04725357Phase 3
• Rofecoxib Efficacy and Safety Evaluation Trial in Hemophilic ArthropathyTerminatedNCT04684511Phase 3
• Adjunctive Celecoxib in Childhood-onset OCD StudyStatus unknownNCT04673578Phase 2
• Pharmacokinetic Interaction Between Tegoprazan and NSAIDs After Multiple Oral Dosing in Healthy Male VolunteersCompletedNCT04639804Phase 1
• Prevention of Taxane-associated Acute Pain Syndrome With EtoricoxibCompletedNCT04565600Phase 2
• Lidocaine Spray Plus Oral Celecoxib for Pain Control During HysterosalpingographyCompletedNCT04505657Not applicable
• I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill PatientsActive, not recruitingNCT04488081Phase 2
• Effect of Pineapple Juice on the Pharmacokinetics of Celecoxib and Montelukast in HumansCompletedNCT04374981Phase 2
• Pregabalin Versus Celecoxib on Sevoflurane and Analgesic Consumption in Spine Fixation SurgeryCompletedNCT04342065Phase 2/3
• Pharmacokinetic and Tolerance Study of Meloxicam Eye Drops in Healthy VolunteersStatus unknownNCT04322175Phase 1
• Celecoxib vs. Acetaminophen/Codeine/Caffeine for Post-operative Analgesia in Rhinoplasty.Status unknownNCT04259333Phase 4
• Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer SurgeryTerminatedNCT04176419Phase 3
• Effect of Celecoxib on Postoperative Analgesia and Disease Severity in AERD Patients with CRSActive, not recruitingNCT04147013Phase 4
• Etoricoxib vs Aceclofenac in the Treatment of Patients With Rheumatoid ArthritisCompletedNCT04144101Phase 4
• Transition From Acute to Chronic Back Pain : Effect of L-dopa,Gender,and Associated Brain PlasticityWithdrawnNCT04082715Phase 2
• Anti-inflammatories and Adolescent SchizophreniaStatus unknownNCT04020588Phase 4
• The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee ArthroplastyCompletedNCT04003350Not applicable
• Pediatric Postoperative Analgesia Herniorrhaphy StudyWithdrawnNCT03922048Phase 2
• Effect of Intravenous Dynastat on Postoperative Sore ThroatStatus unknownNCT03915561Phase 2
• Neoadjuvant Celecoxib in Newly Diagnosed Patients With Endometrial CarcinomaStatus unknownNCT03896113Phase 2
• Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME TrialTerminatedNCT03878524Phase 1
• An Open Label Phase II Study Combining Nivolumab and Celecoxib in Patients With Advanced " Cold " Solid TumorsStatus unknownNCT03864575Phase 2
• Clinical Study to Evaluate Effect on QT/QTc Interval After Multiple Dose of CelecoxibCompletedNCT03822520Phase 1
• Nonopioid Analgesia After Arthroscopic Meniscus SurgeryCompletedNCT03820193Early Phase 1
• Parecoxib vs Paracetamol in the Treatment of Acute Renal ColicCompletedNCT03704623Phase 4
• Multimodal Analgesia in Shoulder ArthroplastyWithdrawnNCT03586934Phase 3
• Serum Creatinine Change / Renal Adverse Effect With Use of Non-steroidal Painkillers in Axial Spondyloarthritis PatientsCompletedNCT03582332Phase 4
• Safety and Activity of F14 for Management of Pain Following Total Knee ReplacementCompletedNCT03541655Phase 2
• Celecoxib Versus Hyoscine Butyl-bromide in Reducing Pain Associated With IUD.CompletedNCT03499743Not applicable
• The Efficacy of 20 mg Parecoxib as an Adjunct to 0.75% Ropivacaine in Supraclavicular Brachial Plexus Block for Upper Limb SurgeryCompletedNCT03480165Phase 3
• Can DFN-15 Terminate Migraine With Allodynia?CompletedNCT03472378Phase 2
• Celecoxib in Colposcopic Directed BiopsyCompletedNCT03464552Phase 4
• Bioequivalence Study of 120 mg Etoricoxib Film-coated TabletsCompletedNCT03422575Not applicable
• Trial to Evaluate Efficacy and Safety of Combination of Diacerein and Celecoxib Administered in Patients With Knee OAStatus unknownNCT03404479Phase 4
• Comparing Postoperative Pain Following COX-2 and Prostanoids ExpressionStatus unknownNCT03391570Not applicable
• Efficacy of Multimodal Analgesia Following Hip ArthroscopyCompletedNCT03351439Not applicable
• Celebrex Premedication in Teeth With Symptomatic Irreversible PulpitisStatus unknownNCT03339544Not applicable
• Radial Extracorporeal Shock Wave Therapy for Chronic Non-specific Low Back PainCompletedNCT03337607Not applicable
• Study on the Pharmacokinetics (PK) of DFN-15 vs Comparator and Food-effect on DFN-15 PK in Healthy Adult SubjectsCompletedNCT03282838Phase 1
• Effects of Nonsteroidal Anti-inflammatory Drug (NSAID) on Inflammatory Lesion of Axial SpondyloarthritisCompletedNCT03190603Phase 4
• Celecoxib Window of Opportunity Trial to Assess Tumor and Stroma ResponsesWithdrawnNCT03185871Phase 2
• Celebrex and Metformin for Postoperative Hepatocellular CarcinomaStatus unknownNCT03184493Phase 3
• Pain Management in Head and Neck Surgery PatientsWithdrawnNCT03121963Phase 4
• The Study to Evaluate Efficacy and Safety of Celecoxib Capsule in Hand Osteoarthritis PatientsCompletedNCT03067194Phase 4
• Efficacy and Safety in a Randomised Acute Pain Study of MR308: STARDOM2.CompletedNCT03062644Phase 3
• Parecoxib Versus Celecoxib Versus Oxycodone in Pain Control for Transcatheter Chemoembolization ProcedureCompletedNCT03059238Phase 3
• Bioavailability of DFN-15 at 3 Different Doses vs. Comparator and to Determine Dose-proportionality of DFN-15 in Fasting Healthy AdultsCompletedNCT03051685Phase 1
• Preventive Effect of Celecoxib on Sorafenib-related Hand Foot Syndrome, a Single Center, Randomized Controlled Clinical TrailCompletedNCT02961998Phase 4
• Celecoxib With Chemotherapy in Localized, Muscle-Invasive Bladder CancerCompletedNCT02885974Phase 1
• Analgesia in Inguinal Hernia Repair Using a Cyclooxygenase-2-specific InhibitorCompletedNCT02884986Not applicable
• Etodolac and Post-bleaching SensitivityCompletedNCT02881619Phase 4
• Effect of Low-Dose Celecoxib on SMN2 in Patients With Spinal Muscular AtrophyTerminatedNCT02876094Phase 2
• A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff RepairCompletedNCT02850211Phase 4
• Pre-Prostatectomy Celecoxib or PlaceboTerminatedNCT02840162Phase 2
• Tramadol Versus Celecoxib in Reducing Pain Associated With IUD InsertionStatus unknownNCT02827487Phase 4
• Perioperative Use of a Selective COX2 Inhibitor in Patients Undergoing Elective Colorectal Surgery: the Effect on Post-operative Bowel Motility and Post-operative PainStatus unknownNCT02790203Not applicable
• Study to Compare the Efficacy and Safety of CELBESTA® and CELEBREX® in Patients With Rheumatoid ArthritisCompletedNCT02780323Phase 4
• NSAIDs Added to Anti-TNF Therapy Versus Anti-TNF Therapy Alone on Progression of Structural Damage in Ankylosing SpondylitisCompletedNCT02758782Phase 4
• Early Parecoxib Usage to Decreases Narcotic Requirement and Length of Stay After Traumatic Rib FractureTerminatedNCT02749409Phase 3
• Concurrent Radiotherapy and/or Cisplatin With or Without Celecoxib in Patients With Primary Oral Squamous Cell CarcinomaStatus unknownNCT02739204Phase 2
• Tramadol Versus Celecoxib for Reducing Pain During Operative Office HysteroscopyStatus unknownNCT02736071Phase 3

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